scholarly journals Determining Relation between Gallstone and Lipid Profile

2018 ◽  
Vol 3 (2) ◽  
pp. 418-422 ◽  
Author(s):  
Rabin Raj Singh ◽  
Sunil Chandra Adhikari ◽  
Ravi Bastakoti ◽  
Sunil Regmi ◽  
Ravindra Baskota ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Serum Cholesterol ◽  
Statistical Significance ◽  
Serum Triglyceride ◽  
P Value ◽  
Number Of Patients ◽  
Increased Risk ◽  
Group A ◽  
Group B ◽  
Low Serum

Introduction: Cholelithiasis is presence of stone in gallbladder. Female sex, obesity, pregnancy, fatty foods, all are associated with an increased risk of developing gallstones. There is paucity of information regarding relation of cholelithiasis and lipid profile. In this study the association of serum lipids to cholelithiasis has been tried to been elucidated.Objectives: The general objective was to determine the relation of Serum lipid in cholelithiasis. The specific objectives were to compare the relation between serum cholesterol, serum triglyceride, serum HDL and serum LDL in patients with and without gallstones.Methodology: A prospective, observational, hospital based study was conducted at Koshi Zonal Hospital from March 2017 to February 2018. Fifty four patients having gallstone (Group A) were compared with equal number of patients without gallstone (Group B). Data was entered into SPSS/MS Excel. Statistical Analysis was done by using Chi-square test. A 95% confidence interval was taken, and P value less than 0.05 was considered as statistically significant.Results: In Group A, 61%(33) patients were of age less than 45 years and 91%(49) were female. In group A, 3.7 %(2) and in group B, 7.4%(4) had raised serum cholesterol. Greater number of patient in group A had raised serum triglyclyceride and LDL as compared to group B. 18.5%(10) of group A had low serum HDL, and 9.3% (5) of group B had low serum HDL. Except for finding of gallstone more common in female, other findings had no statistical significance.Conclusion: There exists an inverse correlation between Serum Cholesterol and serum HDL with gallstone and positive association between serum Triglyceride and serum LDL with cholelithiasis. However the association could not reach the statistical significance.  BJHS 2018;3(2)6:418-422.

scholarly journals INTRAVENOUS REGIONAL ANESTHESIA (BIERS BLOCK);

2012 ◽  
Vol 19 (05) ◽  
pp. 710-714
Author(s):  
Muhammad ASGHER ◽  
ASIM GHAURI ◽  
MUHAMMAD ABDULLAH ◽  
Tariq Abassi
Keyword(s):  
Regional Anaesthesia ◽  
Military Hospital ◽  
P Value ◽  
Complete Evaluation ◽  
Intravenous Regional Anesthesia ◽  
Number Of Patients ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Intravenous Regional Anaesthesia

Objective: To compare the analgesic effects of combination of 0.5% Lidocaine plus Ketorolac in intravenous regionalanaesthesia technique with those of Lidocaine (0.5%) alone to prevent post operative pain after intravenous regional anaesthesia (Biersblock). Study design: Randomized Control Trial. Place and duration of study: The study was carried out at Department of Anaesthesiology,Intensive Care and pain management, Combined Military hospital, Rawalpindi from July 2008 to February 2009. Patients and Methods: Thestudy was conducted after complete evaluation of risk / benefit ratio to the patients. On the basis of random number method the patients weredivided into two equal groups (group A and group B). The number of patients in each group was 75. Group A was assigned Lidocaine in a dose of200mg 40ml of 0.5% solution and group B was assigned injection Ketorolac 30mg added to Lidocaine in a dose of 200mg 40ml of 0.5% solution.The patients were kept in post anaesthesia care unit for two hours and pain intensity was measured by visual analogue scale(VAS) on 15,30minutes,1hour, 1.5 and at 2 hours after the cuff deflation. The analgesic efficacy recorded on the basis of visual analog scale of two groups, wascompared using student’s t - test. p value of less than 0.05 was considered statistically significant. Results: In group A 33 males and 42 femaleswere enrolled for the study while in group B there were 38 males and 37 females. The mean age of the patients in group A was 34.31 ± 6.03years while in group B was 32.99 ± 6.08 years. Patients were also classified according to ASA classification in which 87 patients were classifiedas ASA – I and 63 patients as ASA – II. Group B which received Ketorolac in addition to Lidocaine for Bier’s block had low visual analogue scoresas compared to group A which received only Lidocaine for Bier’s block. P values obtained after the comparison of the mean VAS of two groupsat 15 minutes, 30 minutes, 1 hour, 1.5 hours and 2 hours were all less than 0.05 (0.002 for 15 minutes, 0.004 for 30 minutes, 0.001 for 1 hour,0.004 for 1.5 hours and 0.001 for 2 hours). Conclusions: Ketorolac improves the postoperative analgesia markedly when used with Lidocainein intravenous regional anaesthesia.

scholarly journals A study of lipid parameters among GDM and non GDM pregnant women: a hospital based study

2017 ◽  
Vol 6 (12) ◽  
pp. 5488 ◽  
Author(s):  
Bharathi K. R. ◽  
Vijayalakshmi S. ◽  
Shrunga R. P.
Keyword(s):  
Pregnant Women ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Statistical Significance ◽  
Serum Triglyceride ◽  
Normal Pregnancy ◽  
P Value ◽  
Case Group ◽  
Lipid Levels ◽  
Lipid Parameters

Background: Altered maternal lipid metabolism is common in pregnancy. In women with GDM physiological changes in insulin and lipid levels are exaggerated during pregnancy, leading to significant alterations in lipid levels compared to normal pregnancy. Assessment of raise in certain lipid parameters in pregnant women with GDM and non GDM.Methods: A hospital based case control study done in the Department of OBG AIMS Bellur, Mandya, Karnataka, with sample size of 100 pregnant women. 50 cases of GDM (confirmed by OGCT) and 50 controls (non GDM cases) pregnant women were taken during 1 year study period from June 2015 to June 2016. Mean age of presentation of women was 20-25 yrs. Ethical committee clearance was taken and consent from control and cases was taken. Fasting lipid profile was sent. Parameters obtained were analyzed using student t test for statistical significance.Results: There was no statistical difference in age and parity between control and case group. Triglyceride (cases- 286.4±77.60 mg/dl) (controls-166±26mg/dl), total cholesterol (cases-256.5±41.7 mg/dl) (controls -202.5±20.18mg/dl), VLDL (cases-53.4±13.2 mg/dl) (controls-46.6±13.1mg/dl) showed statistically significant values (p value<0.001). HDL and LDL values did not show any statistical significance (p value >0.5) among GDM and non GDM group. Lipid profile was performed predominately in women in II trimester.Conclusions: Serum triglyceride, total cholesterol and VLDL level are significantly higher among woman with GDM compared to non GDM pregnant women, where in the lipid profile can be used as predictor for gestational diabetes mellitus in future which needs further research.

Stereotactic radiosurgery for brain metastases: a case-matched study comparing treatment results for patients 80 years of age or older versus patients 65–79 years of age

2014 ◽  
Vol 121 (5) ◽  
pp. 1148-1157 ◽  
Author(s):  
Shinya Watanabe ◽  
Masaaki Yamamoto ◽  
Yasunori Sato ◽  
Takuya Kawabe ◽  
Yoshinori Higuchi ◽  
...  
Keyword(s):  
Brain Metastases ◽  
Stereotactic Radiosurgery ◽  
Statistical Significance ◽  
Disease Status ◽  
Competing Risk ◽  
Treatment Results ◽  
Number Of Patients ◽  
Group A ◽  
Group B ◽  
Matched Study

Object Recently, an increasing number of patients with brain metastases, even patients over 80 years of age, have been treated with stereotactic radiosurgery (SRS). However, there is little information on SRS treatment results for patients with brain metastases 80 years of age and older. The authors undertook this study to reappraise whether SRS treatment results for patients 80 years of age or older differ from those of patients who are 65–79 years old. Methods This was an institutional review board–approved, retrospective cohort study. Among 2552 consecutive brain metastasis patients who underwent SRS during the 1998–2011 period, we studied 165 who were 80 years of age or older (Group A) and 1181 who were age 65–79 years old (Group B). Because of the remarkable disproportion in patient numbers between the 2 groups and considerable differences in pre-SRS clinical factors, the authors conducted a case-matched study using the propensity score matching method. Ultimately, 330 patients (165 from each group, A and B) were selected. For time-to-event outcomes, the Kaplan-Meier method was used to estimate overall survival and competing risk analysis was used to estimate other study end points, as appropriate. Results Although the case-matched study showed that post-SRS median survival time (MST, months) was shorter in Group A patients (5.3 months, 95% CI 3.9–7.0 months) than in Group B patients (6.9 months, 95% CI 5.0–8.1 months), this difference was not statistically significant (HR 1.147, 95% CI 0.921–1.429, p = 0.22). Incidences of neurological death and deterioration were slightly lower in Group A than in Group B patients (6.3% vs 11.8% and 8.5% vs 13.9%), but these differences did not reach statistical significance (p = 0.11 and p = 0.16). Furthermore, competing risk analyses showed that the 2 groups did not differ significantly in cumulative incidence of local recurrence (HR 0.830, 95% CI 0.268–2.573, p = 0.75), rates of repeat SRS (HR 0.738, 95% CI 0.438–1.242, p = 0.25), or incidence of SRS-related complications (HR 0.616, 95% CI 0.152–2.495, p = 0.49). Among the Group A patients, post-SRS MSTs were 11.6 months (95% CI 7.8–19.6 months), 7.9 months (95% CI 5.2–10.9 months), and 2.8 months (95% CI; 2.4–4.6 months) in patients whose disease status was modified–recursive partitioning analysis (RPA) Class(es) I+IIa, IIb, and IIc+III, respectively (p < 0.001). Conclusions Our results suggest that patients 80 years of age or older are not unfavorable candidates for SRS as compared with those 65–79 years old. Particularly, even among patients 80 years and older, those with modified-RPA Class I+IIa or IIb disease are considered to be favorable candidates for more aggressive treatment of brain metastases.

Role of intraoperative neuromonitoring of the recurrent laryngeal nerves during thyroid reoperations of recurrent goiter

2017 ◽  
Vol 89 (3) ◽  
pp. 11-15 ◽  
Author(s):  
Jan Sopiński ◽  
Krzysztof Kuzdak ◽  
Masoud Hedayati ◽  
Krzysztof Kołomecki
Keyword(s):  
At Risk ◽  
Statistical Significance ◽  
Operation Time ◽  
Intraoperative Neuromonitoring ◽  
Number Of Patients ◽  
Recurrent Goiter ◽  
Group A ◽  
Procedure Duration ◽  
Recurrent Laryngeal Nerves ◽  
Group B

Reoperations of the thyroid gland are challenging to any surgeon. Such procedures are technically difficult and involve higher risk of complications than primary procedures. Recurrent laryngeal nerve (RLN) palsy is one of such complications The aim of the study was to evaluate the effectiveness of intraoperative neuromonitoring (IONM) in preventing RLN palsy during recurrent goiter operations. Material and methods. We retrospectively analyzed the results of thyroid reoperation performed at the Department of Endocrine, General and Vascular Surgery of Medical University of Lodz in the period from January 2014 to June 2016. The study included 80 patients, who were divided into 2 groups: group A consisted of 27 patients, who had undergone surgery with the use of IONM, while group B included 53 patients, in whom RLN was identified visually. During statistical analysis we took into account the number of nerves at risk, not the number of patients. There were 47 nerves at risk In group A and 86 in group B. We analyzed whether application of IONM had any effect on the frequency of RLN palsy and procedure duration. Results. The frequency of RLN palsy was 10.64% (5/47) in group A and 15.12% (13/86) in group B (no statistical significance, p=0,47). Mean operation time was shorter in group B 71.29 ± 17.125 minutes vs. 75.75 ± 17.94 minutes in group A (no statistical significance, p=0,377). Conclusion. Use of IONM did not significantly reduce the occurrence of RLN palsy and procedure duration.

scholarly journals Effect of a plant versus animal based diet on lipid profile of yoga practicing medical students: a pilot study

2018 ◽  
Vol 6 (4) ◽  
pp. 1207
Author(s):  
Sanasam Meetali ◽  
Shashikiran H. C. ◽  
Prashanth Shetty ◽  
Ganesh Prasad ◽  
Chandrakanth K. K.
Keyword(s):  
Lipid Profile ◽  
Serum Triglyceride ◽  
Gastrointestinal Diseases ◽  
Vegetarian Diet ◽  
Mean Value ◽  
Diet Group ◽  
The Body ◽  
Blood Cholesterol ◽  
Group A ◽  
Group B

Background: Foods play an important role in human health. An excess accumulation of cholesterol in the body is one of the main causes of cardio vascular disease, hypertension, type 2 diabetes mellitus, dyslipidemia and mortality. In the interests of food safety and public health, plants and their compounds are now re-emerging as an alternative approach to treat gastrointestinal diseases. The present study was designed to discuss changes in blood cholesterol levels after the consumption of animal based (non vegetarian) and plant based (vegetarian) food on yoga practising medical students.Methods: Of 81 subjects, a total of 60 subjects within the age group 18 to 22 years were selected for the study and were divided into two groups, non-vegetarian diet group (group A; n=30) and vegetarian diet group (group B; n=30). Subjects in the group A were given a non vegetarian diet and group B a vegetarian diet for a period of 10 days. Assessments were done at baseline and after 10 days.Results: There were no statistically significant changes seen in the lipid profiles of group B and group A after the application of a paired t test. In this study the mean value of total cholesterol, serum triglyceride, serum LDL and serum VLDL were found to be slightly higher in vegetarian group than the non-vegetarian group. Mean value of serum HDL was found to be higher in non-vegetarian group than the vegetarian.Conclusions: The present study concludes that there are more changes in the pre and post lipid profile assessments of the vegetarian group in comparison to the non-vegetarian group.

scholarly journals Comparative Study of Oral Clonidine and Midazolam as Premedication in Pediatric Patients Undergoing Tonsillectomy

2019 ◽  
Vol 4 (1) ◽  
Keyword(s):  
Statistical Significance ◽  
Anxiety Score ◽  
P Value ◽  
Parental Separation ◽  
Oral Clonidine ◽  
Oral Midazolam ◽  
Group A ◽  
Group B ◽  
Double Blinded ◽  
Induction Of Anaesthesia

Background and Aim: Anxiety and fear of operation, injections, physicians, operation theatre environment and parental separation are all traumatizing experiences in children. The aim of the study was to compare the effects of oral midazolam and oral clonidine as premedication in children undergoing tonsillectomy .The preoperative sedation, anxiolytic, acceptance of mask for induction of anaesthesia, intravenous cannulation and post-operative recoverywere assessed in both groups. Methods: Aprospective randomized double blinded study of 100 patients of age group 4 -12 yrs undergoing tonsillectomy under general anaesthesia were selected. They were divided into 2 groups of 50 patients each. Group A (oral clonidine) received 4 mcg/kg 90 minutes before induction. Group B (oral midazolam) received 0.5 mg/kg 90 minutes before induction. The sedation and anxiety score was noted at the time of parental separation. The reaction to IV cannulation was assessed by sedation and anxiety scoring at the same time all of them were taken under GA with controlled ventilation. The Mask acceptance was graded by 5 point scoring system .Grade 3,4 and 5 are satisfactory.They were monitored throughout the surgery for any complications. Post operative status was assessed by Modified Objective Pain score. Results: The sedation score and anxiety score at venipuncture was better with clonidine group with statistical significance (p< 0.000 and<0.003). The mask acceptance was better with clonidine group with statistical significance (p <0.000).Postoperative score was also better with clonidine group with statistical significance of p value <0.000. Conclusion: We concluded that oral clonidine and midazolam can be used as better premedicants to produce optimal sedation and emotional state.Clonidine 4 μg / kg has been shown to be a more effective premedication for children undergoing elective tonsillectomy than midazolam 0.5mg/kg

scholarly journals 1379. Comparison of Inpatient Tuberculosis Screening Methods and Their Effect on Patient Duration in Airborne Isolation

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S501-S501
Author(s):  
Mary Katherine. Theoktisto ◽  
Delvina Ford ◽  
Omar Khan ◽  
Kelly R Reveles ◽  
Jose Cadena
Keyword(s):  
Statistical Significance ◽  
Nucleic Acid Amplification ◽  
Health Concern ◽  
Smear Microscopy ◽  
Screening Methods ◽  
Number Of Patients ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Crude Analysis

Abstract Background Tuberculosis (TB) remains a significant public health concern, and exposure in healthcare settings is prevalent. Current guidelines recommend testing for TB by acid-fast bacilli (AFB) smear microscopy with 3 sputum samples and/or using nucleic acid amplification test (NAAT), and mycobacterium culture. The purpose of this project is to compare how different TB diagnostic tests affect the duration of stay in respiratory isolation. Methods This study was conducted at the Veteran Affairs South Texas hospital, which includes a total of 437 beds. Data were collected retrospectively from medical records. Eligibility included patients admitted to the hospital and placed in airborne isolation for TB screening and diagnosis, had 3 sputum samples collected 8 hours apart and/or had 2 PCR MTB/RIF. Patients were excluded if they had TB or were not undergoing evaluation for TB. Three time periods analyzed included, 3 AFB sputum samples analyzed in-house from December 2012 to January 2014 (Group A), 3 AFB sputum samples analyzed at outside facility during 2013 to 2014 as well as 2 months in 2012 (Group B), and 2 MTB PCR/RIF in house during 2017 and 2018 (Group C). Duration of isolation was compared between groups using the Kruskal–Wallis test. A total number of 815 patients were screened, leaving 105 patients for analysis after exclusion. There were 49 patients analyzed from Group A, 28 from Group B, and 28 from Group C. Results Crude analysis of the data showed numerical differences in the total number of days and hours in isolation between the 3 groups. The average (mean) days in isolation were 4.2 for Group A, 7.4 for Group B, and 5.5 for Group C. There was no statistically significant difference in either days or hours of airborne precautions by “rule out” method. Days of isolation in airborne precautions (median IQR) was 4 for all groups (P = 0.3313). Likewise, hours of airborne precautions had a median IQR of 96 for all groups P = 0.4347. Conclusion Although there was no statistical significance between the groups, crude analysis did show a numerical difference in the mean total airborne days and hours. Lack of statistical difference may be due to low number of patients, timing of order placement for in-house PCR, and longer than expected stay in airborne precautions. Disclosures All authors: No reported disclosures.

To compare the efficacy of Telmisartan and Ramipril in patients of essential hypertension with type 2 diabetes in controlling the blood pressure and improving lipid profile of the patients.

2020 ◽  
Vol 7 (3) ◽  
pp. 73-79
Author(s):  
Dr. Pallavi Vidyadhar Kulkarni ◽  
Dr. P. N. Khandelwal ◽  
Dr. M. D. Kulkarni ◽  
Dr. M. S. Baig
Keyword(s):  
Lipid Profile ◽  
Statistical Difference ◽  
Cardiovascular Complications ◽  
P Value ◽  
Comorbid Condition ◽  
Common Denominator ◽  
Contributing Factors ◽  
Significant Difference ◽  
Group A ◽  
Group B

Background: Hypertension is an extremely common comorbid condition in DM, affecting 20-60% patients with DM. As the common denominator of hypertensive diabetic target organ-disease is the vascular tree, the co-existence of hypertension and DM is devastating to cardiovascular and renal system. Lipids stand one of the major contributing factor in cardiovascular morbidity amongst these patients. Many drugs are available in the market to control this, we have studied the efficacy of Telmisartan and Ramipril in improving the lipid profile of these patients. Observation and Results:  Group A received Telmisartan while Group B received Ramipril. The baseline lab values of both the groups showed no any statistical difference showing the homogeneity of the groups. Similarly there was no any significant difference between the baseline Lipid profile values of TC, LDL, TG & HDL (All P > 0.05). The reduction in mean SBP & DBP was statistically significant over 12 weeks of therapy in both the groups. But there was no statistical difference inter group wise. It was observed that there was statistically significant difference in mean TC levels, mean LDL levels, when two groups are compared after 12 weeks of therapy. (P value < 0.05). While no significant difference was observed in the values of TG & HDL (P value > 0.05). Conclusion: Our study concludes that there is significant correlation between the use of Telmisartan and Ramipril in lowering the lipids in the patients of Diabetes with Hypertension. Lowering the lipids is very important to prevent any cardiovascular complications, which are one of the major contributing factors to the morbidity and mortality amongst these patients.

scholarly journals BENEFITS OF EARLY POST-ERCP LAPAROSCOPIC CHOLECYSTECTOMY: A SINGLE CENTRE PROSPECTIVE STUDY

2021 ◽  
Vol 12 (3) ◽  
Author(s):  
Farhan javed ◽  
Saira Saleem ◽  
Ayesha Rehman ◽  
Faiza Wattoo ◽  
Nadia Bano ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Hospital Stay ◽  
Operative Time ◽  
Statistical Tests ◽  
P Value ◽  
Cross Sectional ◽  
Increased Risk ◽  
Group A ◽  
Study Population ◽  
Group B

ABSTRACT: BACKGROUND & OBJECTIVE: Laparoscopic cholecystectomy (LC) following Endoscopic retrograde cholangiopancreatography (ERCP) is associated with an increased risk of complications. ERCP is associated with increased incidence of complications during LC. Surgery may be performed in same anesthesia with ERCP or up to 6 weeks later. We aimed to determine the benefits of performing LC within 72hrs of ERCP. METHODOLOGY: After institutional ethical approval this prospective cross-sectional study was performed at Madinah Teaching Hospital Faisalabad from April 2019 to June 2020. By performing convenience sampling, all patients undergoing LC after uneventful ERCP in our hospital were included. Study population was divided based on interval between ERCP and Cholecystectomy; Group-A had LC within 72hrs of ERCP, Group B had LC in same hospital stay after 72hrs and Group-C patients were discharged after ERCP and readmitted for LC. Data was collected using custom designed questionnaire, tabulated using Microsoft Excel 2016 and subjected to statistical tests to compare outcomes. Primary outcome was incidence of complications, while operative time, hospital stay and cost were considered as secondary outcomes. p-value of <0.05 was considered significant. RESULTS: Total 75 patients were included in study, 32 in Group-A, 20 in Group-B and 23 in Group-C. Average age was 44.987 ± 14.819 and study population was predominantly female (86.67%). Complication rate, duration of hospital stay and average cost were less in Group A as compared to other groups (p<0.05). Mean operative time in 3 groups was similar. CONCLUSION: LC within 72hrs after ERCP provides superior results in terms of fewer complications, shorter hospital stays and lesser cost.

scholarly journals A comparative study of low dose magnesium sulphate (Dhaka regime) and Pritchard regime for the management of impending eclampsia and eclampsia

2017 ◽  
Vol 6 (6) ◽  
pp. 2180
Author(s):  
. Ranjana ◽  
Abha Rani Sinha ◽  
Chandra Prakash
Keyword(s):  
Magnesium Sulphate ◽  
Low Dose ◽  
Statistical Significance ◽  
Perinatal Outcomes ◽  
P Value ◽  
Entire Treatment Period ◽  
Indian Women ◽  
Group A ◽  
Low Bmi ◽  
Group B

Background: Eclampsia is a common obstetrical emergency though preventable, yet remains a leading cause of maternal and perinatal morbidity and mortality in the developing world. Pritchard regime is most widely used magnesium sulphate regime for control of eclamptic fits but its dose related toxicity is a major concern among Indian women with low BMI and at peripheral institutions where the patients monitoring is limited. The objective was to study the efficacy of low dose MgSO4 regime (Dhaka regime) for control of convulsions in eclampsia and prevention of convulsions in impending eclampsia, to assess the magnesium related toxicity and to analyze the maternal and perinatal outcomes as compared to standard Pritchard regime.Methods: This prospective study was carried out in the Department of obstetrics and Gynaecology at Patna Medical College and Hospital, Patna. Study was done on 80 patients of eclampsia and impending eclampsia. Patients were divided into two groups A and B. Group A (n=40) received low dose MgSO4 regime (Dhaka regime) and Group B (n=40) received standard Pritchard regime. Results were analysed using statistical package of social sciences (SPSS) 21.0. Statistical significance was set at p ≤0.05.Results: In the present study, convulsions were controlled in 95% of eclampsia cases with low dose magnesium sulphate (Dhaka) regime. Recurrence of convulsion was seen in both groups. None of the patients with impending eclampsia in both the groups developed the seizure during entire treatment period. Signs of impending MgSO4 toxicity and the mean amount of magnesium sulphate received was found more in Pritchard regime group (22.5gms in Group A and 39gms in Group B) and was statistically significant with p value <0.001. There were 3 maternal deaths in present study.Conclusions: Low dose magnesium sulphate is as effective as standard Pritchard regime in controlling the eclamptic fits and preventing its recurrence with comparable maternal and perinatal outcome and less chances of magnesium toxicity. This regimen may be more suitable for use in Indian women with low BMI and in resource poor settings where clinical monitoring is limited.

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