scholarly journals A study of lipid parameters among GDM and non GDM pregnant women: a hospital based study

2017 ◽  
Vol 6 (12) ◽  
pp. 5488 ◽  
Author(s):  
Bharathi K. R. ◽  
Vijayalakshmi S. ◽  
Shrunga R. P.
Keyword(s):  
Pregnant Women ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Statistical Significance ◽  
Serum Triglyceride ◽  
Normal Pregnancy ◽  
P Value ◽  
Case Group ◽  
Lipid Levels ◽  
Lipid Parameters

Background: Altered maternal lipid metabolism is common in pregnancy. In women with GDM physiological changes in insulin and lipid levels are exaggerated during pregnancy, leading to significant alterations in lipid levels compared to normal pregnancy. Assessment of raise in certain lipid parameters in pregnant women with GDM and non GDM.Methods: A hospital based case control study done in the Department of OBG AIMS Bellur, Mandya, Karnataka, with sample size of 100 pregnant women. 50 cases of GDM (confirmed by OGCT) and 50 controls (non GDM cases) pregnant women were taken during 1 year study period from June 2015 to June 2016. Mean age of presentation of women was 20-25 yrs. Ethical committee clearance was taken and consent from control and cases was taken. Fasting lipid profile was sent. Parameters obtained were analyzed using student t test for statistical significance.Results: There was no statistical difference in age and parity between control and case group. Triglyceride (cases- 286.4±77.60 mg/dl) (controls-166±26mg/dl), total cholesterol (cases-256.5±41.7 mg/dl) (controls -202.5±20.18mg/dl), VLDL (cases-53.4±13.2 mg/dl) (controls-46.6±13.1mg/dl) showed statistically significant values (p value<0.001). HDL and LDL values did not show any statistical significance (p value >0.5) among GDM and non GDM group. Lipid profile was performed predominately in women in II trimester.Conclusions: Serum triglyceride, total cholesterol and VLDL level are significantly higher among woman with GDM compared to non GDM pregnant women, where in the lipid profile can be used as predictor for gestational diabetes mellitus in future which needs further research.

scholarly journals A study among the Gestational Diabetes Mellitus and Non-Gestational Diabetes Mellitus pregnant women highlighting the variations in lipid parameters attending ante natal clinics at Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha, India

2019 ◽  
Vol 8 (1) ◽  
pp. 30
Author(s):  
Sambit Das ◽  
Mahesh Rath ◽  
Lipsa Das ◽  
Kasturi Bharadwaj
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Statistical Significance ◽  
P Value ◽  
Lipid Levels ◽  
Medical College

Background: Wide variation in the lipid profile in pregnancy is quite common. Exaggerated changes in insulin and lipid levels in women with GDM during pregnancy, lead to significant alterations in lipid levels in comparison to normal pregnancy. Lipid metabolism during pregnancy has a significant role to play in the aetiology and pathogenesis of GDM as is indicated by various studies previously.Methods: A hospital-based case control study was conducted at Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha in the Department of Endocrinology. The sample size was 100 pregnant women. Study period was of one year from June 2018 to June 2019. In women of both the groups, i.e., with GDM and without GDM the mean age of presentation were 20-25 yrs. Out of the 100 cases, we took 50 patients of GDM in the cases group and 50 patients of non GDM pregnant women as control group. Fasting lipid profile was sent to the hospital laboratory analyzed by Tinder’s methods. The results thus obtained were analyzed using student ‘t’ test for statistical significance using SPSS version 20.Results: There was no statistical difference in age and parity between control and case group. Triglyceride (cases- 286.4±77.60 mg/dl) (controls-166±26mg/dl), total cholesterol (cases-256.5±41.7 mg/dl) (controls - 202.5±20.18mg/dl), VLDL (cases-53.4±13.2 mg/dl) (controls-46.6±13.1mg/dl) showed statistically significant values (p value<0.001). HDL and LDL values did not show any statistical significance (p value >0.5) among GDM and non GDM group. Lipid profile was performed predominately in women in II trimester.Conclusions: In comparison to non GDM women, it was observed that serum triglyceride, total cholesterol and VLDL level are significantly higher in woman with GDM. Whether lipid profile can be used as a predictor for gestational diabetes mellitus in future needs further research.

scholarly journals A Study of Serum Lipid Profile Changes in Children with Dengue Haemorrhagic Fever and its Correlation with Severity in a Tertiary Care Hospital

2020 ◽  
Author(s):  
A Prabhuraj ◽  
KS Kumaravel ◽  
V Anu Rekha ◽  
A Nithiyapriya ◽  
P Sampathkumar ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Serum Lipid ◽  
Pearson Correlation ◽  
Statistical Significance ◽  
Density Lipoprotein ◽  
Serum Levels ◽  
Denv Infection ◽  
Lipid Levels ◽  
Serum Lipid Levels

Introduction: Dengue Virus (DENV) infection now remains as the most rapidly spreading viral disease worldwide. Lower lipid level occurs in critically ill patients with DENV infection and is postulated as an independent predictor of the clinical outcome. Aim: To find the correlation between serum lipid levels and severity in children admitted with various grades of Dengue Haemorrhagic Fever (DHF) and secondarily to correlate serum lipid levels with factors like platelet count and duration of hospital stay. Materials and Methods: This was a prospective descriptive study done in the Paediatric ward from October 2019 to December 2019. Febrile Children with a platelet count of less than 1 lakh/cu.mm and positive for DENV IgM antibodies by Enzyme Linked Immuno Sorbent Assay (ELISA) formed the study group. Demographic details, number of days of fever on admission, duration of stay in hospital and severity grading of DENV infection as per the National guidelines were collected. These children were evaluated with Complete Blood Counts (CBC), fasting lipid profile, X-ray chest and ultrasound abdomen. Mean and standard deviation was used for categorical variables. Chi-square test was used to assess the strength of association between lipids and severity of DENV infections. Pearson correlation coefficient was used to assess R value between length of stay and serum lipid levels. Results: The Total Cholesterol, Low Density Lipoprotein (LDL), Triglyceride and Very Low Density Lipoprotein (VLDL) showed a simple linear decline as the severity grade advanced from grade I to grade IV. However, statistical significance was found only for total cholesterol and LDL with p-values of 0.046 and 0.041 respectively. The distribution of High Density Lipoprotein (HDL) across the grades of severity did not follow any pattern and was randomly distributed. On analysis of Pearson correlation between number of days of hospital stay and lipid profile, statistical significance was observed for LDL alone (p=0.023). Conclusion: The serum levels of total cholesterol and LDL were significantly reduced in severe grades of DHF. Serum levels of total cholesterol and LDL can be used as an economical surrogate marker to predict the severity of DHF at the time of admission.

scholarly journals In the Pre-eclamp sia and Normotensive Patient- Lipid Profile Study

2017 ◽  
Vol 29 (2) ◽  
pp. 1-4
Author(s):  
Jamila Khatun ◽  
Shamima Amir
Keyword(s):  
Pregnant Women ◽  
Lipid Profile ◽  
Lipoprotein Metabolism ◽  
Serum Triglyceride ◽  
Hdl Cholesterol ◽  
Normal Pregnancy ◽  
College Hospital ◽  
Cross Sectional ◽  
Normotensive Patient ◽  
Medical College

Pre-eclampsia is associated with substantial risks for the fetus and mother. Disorders of lipoprotein metabolism are reported to be a major cause of hypertension and proteinuria in pre-eclampsia. This was a cross-sectional comparative study carried out in the Department of Obstetrics and Gynecology, Sylhet, M.A.G Osmani Medical College Hospital, Sylhet during December 2013 to May 2014. 50 pre-eclampsia and 50 normotensive pregnant women's serum lipid profile were selected according to inclusion and exclusion criteria. Fasting lipid profile was measured after 10-12 hours overnight fasting. The mean age (25.12 # 3.98 years vs 24.94 # 3.90 years; p=0.820), gestational age (36.80 # 0.70 weeks vs 36.9 # 1.1 weeks ; p=0.144), and BMI (21.43 # 2.09kg/M2 vs 22.02 # 1.73kg/M2, p=0.131) were statistically similar in both pre-eclamptic women and the control pregnant women. SBP (163.70 #11.24mm of Hg vs 115.10 # 9.39mm of Hg; p<0.001) and DBP (103.6 #9.4mm of Hg vs 71.50 #5.37mm of Hg p<0.001) were significantly higher in pre-eclamptic women than that of normotensive pregnant women. Serum total cholesterol (227.56 # 55.79mg/dl vs 194.56 # 43.33mg/dl, p=0.001). serum LDL-cholesterol (147.72 #51.03mg/dl vs 119.43 # 37.17mg/dl; p=0.002) and serum triglyceride (232.06 # 65.54mg/dl vs 157.44 # 64.24mg/dl p<0.001) were significantly higher in pre- eclampsia than that of normal pregnancy; while serum HDL- cholesterol (38.96 # 2.93 mg/dl vs 45.82 # 6.11 mg/dl; p <0.001) was significantly lower in pre-eclampsia than that of control pregnancy. An abnormal lipid profile has a direct effect on endothelial dysfunction. Early detection of these parameters may help patient by preventing complications in pre-eclampsia.Medicine Today 2017 Vol.29(2): 1-4

scholarly journals BMI Modulates the Effect of Thyroid Hormone on Lipid Profile in Euthyroid Adults

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Yanqiu Wang ◽  
Qinglei Yin ◽  
Min Xu ◽  
Qicheng Ni ◽  
Weiqing Wang ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Ldl Cholesterol ◽  
Statistical Significance ◽  
Hdl Cholesterol ◽  
Normal Weight ◽  
Weight Group ◽  
Cholesterol Levels ◽  
Lipid Parameters

The impacts of thyroid hormones (TH) on lipid profile in euthyroid adults have gained much attention. It is currently unknown whether BMI influences such interaction. In the present study, we investigate the role of BMI in modulating the association between TH and lipid parameters in 1372 euthyroid healthy adults. Our results show that thyroid parameters are differentially associated with lipid profile. FT3 is positively correlated with total cholesterol (β=0.176±0.046, P<0.001) and LDL cholesterol levels (β=0.161±0.040, P<0.001). FT4 is negatively correlated with TG (β=−0.087±0.029, P<0.01) while positively correlated with HDL cholesterol levels (β=0.013±0.005, P<0.01). TSH is positively associated with TG (β=0.145±0.056, P<0.05) and total cholesterol levels (β=0.094±0.030, P<0.01). Importantly, BMI modulates the effect of TH on lipid profile: the interaction of FT4 and BMI and the interaction of FT3 and BMI reach statistical significance in predicting TG and HDL cholesterol levels, respectively. Stratified according to BMI levels, most associations between TH and lipid profile are significant only in normal-weight group. In conclusion, in euthyroid adults, high normal FT3, TSH levels, and low normal FT4 levels are associated with unfavorable lipid profile. BMI mediates the effect of thyroid function on lipid profile in euthyroid adults.

scholarly journals Determining Relation between Gallstone and Lipid Profile

2018 ◽  
Vol 3 (2) ◽  
pp. 418-422 ◽  
Author(s):  
Rabin Raj Singh ◽  
Sunil Chandra Adhikari ◽  
Ravi Bastakoti ◽  
Sunil Regmi ◽  
Ravindra Baskota ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Serum Cholesterol ◽  
Statistical Significance ◽  
Serum Triglyceride ◽  
P Value ◽  
Number Of Patients ◽  
Increased Risk ◽  
Group A ◽  
Group B ◽  
Low Serum

Introduction: Cholelithiasis is presence of stone in gallbladder. Female sex, obesity, pregnancy, fatty foods, all are associated with an increased risk of developing gallstones. There is paucity of information regarding relation of cholelithiasis and lipid profile. In this study the association of serum lipids to cholelithiasis has been tried to been elucidated.Objectives: The general objective was to determine the relation of Serum lipid in cholelithiasis. The specific objectives were to compare the relation between serum cholesterol, serum triglyceride, serum HDL and serum LDL in patients with and without gallstones.Methodology: A prospective, observational, hospital based study was conducted at Koshi Zonal Hospital from March 2017 to February 2018. Fifty four patients having gallstone (Group A) were compared with equal number of patients without gallstone (Group B). Data was entered into SPSS/MS Excel. Statistical Analysis was done by using Chi-square test. A 95% confidence interval was taken, and P value less than 0.05 was considered as statistically significant.Results: In Group A, 61%(33) patients were of age less than 45 years and 91%(49) were female. In group A, 3.7 %(2) and in group B, 7.4%(4) had raised serum cholesterol. Greater number of patient in group A had raised serum triglyclyceride and LDL as compared to group B. 18.5%(10) of group A had low serum HDL, and 9.3% (5) of group B had low serum HDL. Except for finding of gallstone more common in female, other findings had no statistical significance.Conclusion: There exists an inverse correlation between Serum Cholesterol and serum HDL with gallstone and positive association between serum Triglyceride and serum LDL with cholelithiasis. However the association could not reach the statistical significance.  BJHS 2018;3(2)6:418-422.

scholarly journals Perbedaan Rerata Kadar Profil Lipid pada Preeklampsia dengan Kehamilan Normal pada Etnik Minangkabau

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Helen Evelina Siringoringo ◽  
Yusrawati Yusrawati ◽  
Eva Chundrayetti
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Normal Pregnancy ◽  
T Test ◽  
P Value ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Mean ◽  
The Difference ◽  
Cross Sectional Design

AbstrakPreeklampsia-eklampsia sampai saat ini masih merupakan disease of theory. Kelainan yang terjadi pada penyakit ini adalah disfungsi endotel yang dapat disebabkan oleh perubahan kadar profil lipid. Tujuan penelitian ini adalah mengetahui perbedaan rerata kadar profil lipid pada preeklampsia dengan kehamilan normal pada etnik Minangkabau. Penelitian observasional dengan rancangan cross sectional ini dilakukan di RSUP dr. M. Djamil Padang, RS Reksodiwiryo Padang dan UPTD Laboratorium Kesehatan Daerah Sumatera Barat. Subjek terdiri dari 2 kelompok yang diambil secara consecutive sampling dengan jumlah masing-masing 27 orang. Pemeriksaan profil lipid dilakukan dengan metode kalorimetri. Analisis data dilakukan secara uji statistik independent t-test. Hasil penelitian diperoleh rerata kadar total kolesterol pada kelompok preeklampsia dan kehamilan normal adalah 270,19+68,955 mg/dL dan 247,56+44,415 mg/dL dengan nilai p=0,158, rerata kadar trigliserida pada kelompok preeklampsia dan kehamilan normal adalah 296,07±157,993 mg/dL dan 272,89±84,608 mg/dL dengan nilai p=0,504, rerata kadar HDL pada kelompok preeklampsia dan kehamilan normal adalah 51,93±19,882 mg/dL dan 63,33±11,222 mg/dL dengan nilai p=0,012, rerata kadar LDL pada kelompok preeklampsia dan kehamilan normal adalah 159±52,038 mg/dL dan 129,67±38,692 mg/dL dengan nilai p=0,023, rasio perbandingan LDL/HDL pada kelompok preeklampsia dan kehamilan normal adalah 3,86 dan 2,04. Dari hasil penelitian dapat disimpulkan pada kedua kelompok tidak ada perbedaan kadar kolesterol total dan trigliserida, tetapi ada perbedaan kadar HDL dan LDL , rasio perbandingan LDL/HDL lebih tinggi pada preeklampsia daripada kehamilan normal.Kata kunci: preeklampsia, total kolesterol, trigliserida, HDL, LDL, etnik Minangkabau AbstractPreeclampsia-eklampsia still being a disease of theory. One of abnormality accured in preeclampsia is endothelial disfunction that is caused by changes in lipid profile. The objective of this study was to find out the difference of lipid profile mean level in preeclampsia and normal pregnancy at Minangkabau Ethnic. This was an observational study with cross-sectional design at  dr. M.djamil Padang Hospital, dr Reksodiwiryo Hospital and UPTD regional health laboratory of West Sumatera. The subjects consist of two groups, choosen by consecutiteve sampling. Each group consist of 27 subjects. Lipid profile was examined by using independent calorimetric methode. The data analyzed statistically by independent t-test. The result of this study showed mean level of total cholesterol in preeclamsia and normal pregnancy were 270.19±68.955 mg/dL and 247.56±44.415 mg/dL with p-value 0.158. The mean levels of triglyceride in preeclampsia and normal pregnancy were 296.07±157.993 and 272.89±44.415 mg/dL with p-value 0.504. The mean level of HDL in preeclampsia and normal pregnancy were 51.93±19.882 mg/dL and 63.33 mg/dL p-value 0.012. The mean level of LDL in two groups were 159±52.038 mg/dL and 129.67±38.692 mg/dL with p-value 0.023 and the mean levels of LDL/HDL ratio were 3.86±3,09 mg/dLin  preeclampsia and 2,08±0,64 in normal pregnancy. It can be concluded that there is no significant difference in total cholesterol and triglyseride between preeclampsia and normal in HDL and LDL and there is significant difference in LDL/HDL ratio between preeclampsia and normal pregnancy at Minangkabau Ethnic.Keywords: preeclampsia, total cholesterol, triglyceride, HDL, LDL, Minangkabau Ethnic

scholarly journals Correlation of plasma lipid levels and histopathological grading in patients with oral squamous cell carcinoma and its pre-cancerous lesions

2018 ◽  
Vol 4 (6) ◽  
pp. 1436
Author(s):  
Mohini Singh ◽  
Abhishek Bahadur Singh ◽  
Abhijeet Singh ◽  
S. P. Agarwal
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Lipid Profile ◽  
Cell Carcinoma ◽  
Total Cholesterol ◽  
Squamous Cell ◽  
Serum Lipid ◽  
Statistical Significance ◽  
Plasma Lipid ◽  
Lipid Levels

<p class="abstract"><strong>Background:</strong> Lower levels of lipid in proliferating tissues and in blood compartments may occur due to ongoing process of oncogenesis. The evidence regarding hypolipidemia as a predisposing factor for malignancy is scarce. Therefore, this study was undertaken to study alteration of plasma lipid levels in patients diagnosed with oral squamous cell carcinoma (OSCC) and its oral pre-cancerous (OPC) lesions and also to compare the plasma lipid profile in different grades of OSCC.</p><p class="abstract"><strong>Methods:</strong> A single centre prospective cross sectional study was carried out among 150 consecutive patients of OSCC and OPC lesions. The diagnosis of all lesions was confirmed histopathologically and grading was also done for each lesion based on degree of differentiation and keratinization of tumour cells. Serum total cholesterol, HDL, TG, LDL was estimated by using semi-automated chemical analyzer. The lipid levels were compared by using unpaired t-test between two strata whereas one way analysis of variance (ANOVA) with Tukey’s post-hoc tests was used among more than two strata.  </p><p class="abstract"><strong>Results:</strong> Total cholesterol, TG, HDL, and LDL were significantly reduced in OSCC and OPC groups when compared with the reference values. Serum TC, LDL and HDL levels were found to be decreased with the loss of differentiation in histological grading but with no statistical significance.</p><p class="abstract"><strong>Conclusions:</strong> It can be inferred that there is an inverse relationship between the serum lipid profile values of TC, HDLC, TG, LDL and OSCC as well as OPC patients. The lower serum lipid status may be considered a useful indicator for initial changes occurring in neoplastic cells.</p>

scholarly journals A study on lipid profile in subclinical hypothyroidism of patients attending a tertiary care hospital

2020 ◽  
Vol 11 (SPL2) ◽  
pp. 6-12
Author(s):  
Ashwin Raj H ◽  
Ananthi N ◽  
Sabarinathan M
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Subclinical Hypothyroidism ◽  
Human Subjects ◽  
Statistical Significance ◽  
Density Lipoprotein ◽  
High Density ◽  
P Value ◽  
Low Density ◽  
High Statistical Significance

Subclinical hypothyroidism is also known as mild hypothyroidism, early thyroid failure, preclinical hypothyroidism and decreased thyroid reserve. Subclinical hypothyroidism is defined as a high serum thyroid-stimulating hormone concentration and normal serum total or free thyroxine and triiodothyronine concentrations associated with few or no symptoms and signs of hypothyroidism and thus subclinical hypothyroid disease is diagnosed by laboratory findings.Subclinical hypothyroidism is far more common than overt hypothyroidism. The prevalence of subclinical hypothyroidism is relatively high and ranges from 4%-8.5% and maybe as high as 20% in women older than 60years. Subclinical hypothyroidism is more common in elderly women than men. It is found twice as often in women as in men. Thyroid hormones have a known effect on heart rate & cardiac excitability. Cardio vascular system is the major system affected by subclinical hypothyroidism. Subclinical hypothyroidism patients have an increased risk of “atherosclerosis” & coronary artery disease. Subclinical hypothyroidism patients will have an increased level of total cholesterol, triglyceride, low-density lipoprotein and decreased level of high-density lipoprotein, leading to “atherosclerosis”. This study was conducted totally on 110 human subjects of age group 18-60 years. Among the 110 human subjects, 55 were Euthyroid controls and 55 were subclinical hypothyroid cases. Serum total cholesterol, serum triglycerides, serum low-density lipoproteins, levels were increased in subclinical hypothyroid cases than Euthyroid controls with a high statistical significance with the P-value <0.001 and serum high-density lipoproteins levels are decreased in subclinical hypothyroid cases than Euthyroid controls with a high statistical significance with the P-value <0.001. Hence, it should be made mandatory that the estimation of lipid profile should be made as a routine investigation in all cases of subclinical hypothyroidism.

scholarly journals Effect on lipid profile due to prolong Valproic acid intake

2021 ◽  
Vol 15 (7) ◽  
pp. 1497-1499
Author(s):  
Rao. S Aziz ◽  
Usman Saeed ◽  
Liaqat Ali ◽  
Muhammad Arshad ◽  
Roman Abbas ◽  
...  
Keyword(s):  
Valproic Acid ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Cholesterol Oxidase ◽  
Venous Blood ◽  
Case Group ◽  
Long Duration ◽  
And Control ◽  
Relationship Of

Background: Valproic acid (VA) serve as the antimigraine , anti-mental disturbances agent and antiepileptic medicine. After using va, metabolic rearrangements seen in patients that include alteration in lipoproteins levels; Aim: To discuss the effects of VA after using for long duration on total levels of cholesterol in adult. Methods: About Eighty candidates participated and they were divided into two groups namely, case group (40 candidates) and control groups (40 candidates). All the candidates were asked for collection of venous blood sample in order to determine total cholesterol serum level among them via aid of enzymatic cholesterol oxidase phenol 4-aminoantipyrine peroxidase. Results: By the aid of the logistic regression analysis, the relationship of the long-term VA treatment and the level of total cholesterol was obtained. With respect to our analysis, there is a co relation between total levels of cholestrol and long term usage of VA (P=0.003). Conclusions: In a net shell, by using VA for long duration, the total level of cholesterol in adults reduces. Keywords: Lipid profile, side effects, total cholesterol, valproic acid

scholarly journals A Comparative Study of Lipid Profile in Obese and Nonobese Men attending Master Health Checkup

2017 ◽  
Vol 21 (2) ◽  
pp. 73-75
Author(s):  
S Vinod Babu ◽  
Anusha R Jagadeesan ◽  
Jothimalar Ramalingam
Keyword(s):  
Comparative Study ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Ldl Cholesterol ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
P Value ◽  
Health Checkup ◽  
Group I ◽  
Significant Difference

ABSTRACT Introduction Obesity is emerging as an epidemic worldwide. Obesity is associated with a number of comorbid conditions, such as diabetes mellitus, hypertension, cancer, dyslipidemia, cardiovascular abnormalities, anemia, obstructive sleep apnea, and psychosocial abnormalities. Aim This study aims at comparing the lipid profile levels of obese and nonobese men. Materials and methods This was a case—control study conducted at a tertiary care center. Totally, 80 men in the age group of 20 to 47 years attending the master health checkup were included in the study, out of which 40 men with normal body mass index (BMI) of 18 to 25 belonged to group I and 40 men with increased BMI of 30 and above belonged to group II. Lipid profile parameters, such as triglycerides (TGLs), total cholesterol, high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol were estimated in them. The data were statistically analyzed using Statistical Package for the Social Sciences (SPSS) software version 15.0. Results Statistically significant difference was found in the total cholesterol levels with a p-value of 0.040 while the difference in LDL cholesterol was statistically highly significant with a p-value of 0.040. Conclusion Among lipid profile parameters, only total cholesterol and LDL cholesterol showed significant difference between the obese and nonobese individuals. However, the other parameters like HDL cholesterol and TGLs did not show any significant difference. How to cite this article Babu SV, Jagadeesan AR, Ramalingam J. A Comparative Study of Lipid Profile in Obese and Nonobese Men attending Master Health Checkup. Indian J Med Biochem 2017;21(2):73-75.

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