scholarly journals Prevalence of Hypovitaminosis D in Patients Visiting a Tertiary Care Center in Chitwan, Nepal

2019 ◽  
Vol 15 (2) ◽  
pp. 84-92
Author(s):  
Kushal Bhattarai ◽  
Nilu Manandhar ◽  
Sarita Dhakal
Keyword(s):  
Vitamin D ◽  
Care Center ◽  
Tertiary Care ◽  
Large Body ◽  
Serum Vitamin ◽  
Hypovitaminosis D ◽  
Demographic Variables ◽  
High Rate ◽  
Care Hospital ◽  
Serum Vitamin D

Background: As documented by a large body of evidences, Hypovitaminosis D prevails both in the general and the hospitalized populations. We conducted this study to determine the prevalence of hypovitaminosis D amongst the patients visiting a tertiary care hospital and compare the rate gender-wise, across different categories of socio-demographic variables. Methods: It was a cross-sectional study (retrospective chart review) based on the hospital registry of patients at College of Medical Sciences and Teaching Hospital, Bharatpur, Chitwan, Nepal. From the registry, we retrieved the socio-demographic variables (age, gender, ethnicity and season) along with serum vitamin D (25-hydroxy-cholecalciferol) concentrations of the study subjects from January 2015 to August 2018, for our analysis. Hypovitaminosis D was defined as serum vitamin D <30 ng/mL (insufficiency: 20-30ng/mL and deficiency: <20 ng/mL). Results: The overall prevalence of hypovitaminosis D was 70.7% (insufficiency: 35.9% and deficiency: 34.8%), 72.4% (females), 64.2% (males), 76.3% (first age-quartile), 74.5% (miscellaneous ethnic group), and 73.9% (Spring). Females had higher prevalence rates of hypovitaminosis D (and lower median serum 25-hydroxy-cholecalciferol lev-els) as compared to males, in overall participants, and those under each category of age, ethnicity and season (except Winter). Conclusions: The greater prevalence of hypovitaminosis D in the females than the males in the face of high rate in the overall hospital-visiting clearly calls for necessary strategies in the form of further studies and judicious prescription of supplementary vitamin D in the target population.

scholarly journals A Study on Vitamin D Levels in Patients Attended at OPD of A Tertiary Care Hospital of Chattogram

2020 ◽  
Vol 18 (2) ◽  
pp. 37-40
Author(s):  
Shaheda Ahmed ◽  
Md Jalal Uddin ◽  
AYM Masud Reza Khan
Keyword(s):  
Vitamin D ◽  
Tertiary Care ◽  
Serum Vitamin ◽  
Hypovitaminosis D ◽  
Whole Body ◽  
Care Hospital ◽  
Mineral Density ◽  
Female Ratio ◽  
Serum Vitamin D ◽  
Vitamin D Levels

Background: Vitamin D is a fat soluble vitamin, having important role in calcium and phosphorous metabolism. Many researches support the role of vitamin D against cancer, cardiovascular diseases, fractures and falls, cognitive disorders, Parkinsonism, auto-immune diseases, respiratory ailments and depression. Thus Vitamin D Deficiency (VDD) is an alarming public problem. Purpose of this study was to measure the frequency of hypovitaminosis D among different age and sex group of Chattogram, Bangladesh. Materials and methods: A cross sectional hospital based observational study was conducted over a period of six months from February 2018 to July 2018 at a leading diagnostic complex and hospital of Chattogram. A total of 243 patients were included in the study. Number of male and female respondents were 86 and 157 respectively. Age range was 15-85 years. Blood samples were collected aseptically after an oral informed consent. Serum vitamin D levels were estimated using standard laboratory technique (Chemiluminescent microparticle immunoassay method). Results: Among 243 respondents, male female ratio was 1:1.83, mean age was 47± 16.3 years, prevalence of hypovitaminosis was 82%, among male hypovitaminosis was found in 78% cases, whereas among female it was a bit higher with 84%. Sex difference was strongly significant with p value of < 0.01. Conclusion: The present study has limitation with estimation of only vitamin D, in absence of valuable indicators of bone health like serum calcium, bone mineral density and parathyroid hormone. Factors like, less outdoor activities, obesity or covering whole body (Abaiya or burkah) in case of Muslim women, which could be responsible for more hypovitaminosis in case of female was not noticed. But it was very much clear that 45-60 years age group was the most vulnerable with highest level of hypovitaminosis-D in both sexes. Chatt Maa Shi Hosp Med Coll J; Vol.18 (2); July 2019; Page 37-40

scholarly journals Status of Vitamin D among Patients Visiting a Tertiary Care Centre in Rupandehi, Nepal

2021 ◽  
Vol 9 (4) ◽  
pp. 256-260
Author(s):  
Tirtha Narayan Shah ◽  
Amar Kumar Sinha ◽  
Krishna Kumar Jha ◽  
Ram Jiban Prasad
Keyword(s):  
Vitamin D ◽  
Tertiary Care ◽  
Age Groups ◽  
Serum Vitamin ◽  
Hypovitaminosis D ◽  
Target Population ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Serum Vitamin D ◽  
High Level

Serum vitamin D is one of the fat-soluble vitamin which has the role in maintenance of calcium and phosphorus levels  and ultimately proper bone health and various physiological processes.  Although many studies prevail hypovitaminosis D, we focused to find out the pattern of  elevated or decreased  serum vitamin D level as its deficiency and surplus have adverse effects to our health.. For this, a retrospective study was done from the records present in a hospital laboratory of Devdaha Medical College and Research Institute (DMCRI), Rupandehi, Nepal from January 2018 to December 2020 where 201 participants with 70.1% male and 29.9% female with different age groups were present. From total participants, 14.9% had deficient, 42.8% had insufficient, 35.3% had sufficient and 7%  had high level of serum vitamin D. Male had 2.9% deficient and 14,9% insufficient vitamin D whereas female had 11.9% deficient, 27.8% insufficient and 7.0% surplus vitamin D. The greater prevalence of hypovitaminosis D in the females than the males could be overcome by the necessary strategies in the form of further studies and judicious supplementation vitamin D in the target population by monitoring the level of serum vitamin D. Int. J. Appl. Sci. Biotechnol. Vol 9(4): 256-260.

scholarly journals Evaluation of vitamin D profile in juvenile idiopathic arthritis

2021 ◽  
Author(s):  
Madhumita Nandi ◽  
Md Abu Sayeed Mullick ◽  
Arnab Nandy ◽  
Moumita Samanta ◽  
Sumantra Sarkar ◽  
...  
Keyword(s):  
Vitamin D ◽  
Juvenile Idiopathic Arthritis ◽  
Disease Activity ◽  
Tertiary Care ◽  
Serum Vitamin ◽  
Inactive Disease ◽  
Categorical Variables ◽  
Care Hospital ◽  
Serum Vitamin D ◽  
Activity Groups

ABSTRACT Objective To observe the association between serum vitamin D level and disease activity in juvenile idiopathic arthritis (JIA). Methods The observational study was conducted at a tertiary care hospital during 2017-2019. Patients suffered from JIA were recruited through purposive sampling which was stratified by the disease activity based on the Juvenile Arthritis Disease Activity Score 27 (JADAS27) criteria. Serum vitamin D was estimated alongside other laboratory parameters. The numerical and categorical variables were analysed with appropriate statistical tests. Results 40 subjects were studied where inactive disease was observed in nine subjects (22.5%), five subjects (12.5%) were found to be in low disease activity and moderate disease activity groups each, and twenty-one subjects (52.5%) had high disease activity. Considering the total sample size of the study, the mean (SD) JADAS27 score and serum vitamin D level were observed to be 12.02 (11.31) and 23.10 (5.93) respectively. A negative correlation was found between the JADAS27 score and serum vitamin D (r= -0.67). The corrected Chi-square test had revealed significant association between the status of serum vitamin-D and disease activity groups (=16.28; p &lt; .001). Conclusions In JIA, higher grade of disease activity was found to be significantly associated with lower serum vitamin D.

scholarly journals Vitamin-D Deficiency among Psychiatric Outpatients Attending Tertiary Care Hospital

2020 ◽  
Vol 16 (4) ◽  
pp. 195-200
Author(s):  
Arati Thapa ◽  
Mukesh Karki ◽  
Aradhana Thapa
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Teaching Hospital ◽  
Psychiatric Illness ◽  
Psychiatric Patients ◽  
Tertiary Care ◽  
Serum Vitamin ◽  
Care Hospital ◽  
Medical Sciences ◽  
Serum Vitamin D

Abstract Background: Vitamin D deficiency is associated with various physical and mental illness. This study aimed to estimate the prevalence of vitamin D deficiency among patients with psychiatric illness who visited Psychiatry outpatient department of College of Medical Sciences and Teaching Hospital, Chitwan, Nepal and investigate association of vitamin D with clinical characteristics and psychiatric illness. Methods: A total of 129 who attended Psychiatry OPD of College of Medical Sciences and Teaching Hospital were enrolled over a period of 4 months after taking informed written consent. Psychiatric diagnoses were established by attending psychiatrists as part of the routine assessment using ICD 10/DCR criteria. Serum vitamin D was assessed by standard method. Data was analyzed using SPSS. Results: Among 129 participants, one hundred and seven patients (82.9%) showed vitamin D level below normal range. Thirty one (24%) had vitamin D deficiency, seventy six (58.9%) had vitamin D insufficiency and twenty two (17.1%) had normal vitamin D level. The mean level of vitamin D was 24.11± 10.19. However, there was no significant association noted between vitamin D state and socio demographic profile and psychiatric illness. Conclusions: We have found a high percentage of vitamin D deficiency among psychiatric patients in our study. Thus, screening for vitamin D deficiency should be considered as an important part of assessment of patients with major psychiatric illnesses.

scholarly journals UTERINE ATONY;

2014 ◽  
Vol 21 (06) ◽  
pp. 1117-1121
Author(s):  
Shazia Majid Khan ◽  
Mohammad Saeed ◽  
Ghulam Mustafa ◽  
Haq Dad Durrani
Keyword(s):  
Vitamin D ◽  
Blood Loss ◽  
Vitamin D Deficiency ◽  
Gestational Age ◽  
Tertiary Care ◽  
Serum Vitamin ◽  
Uterine Atony ◽  
Care Hospital ◽  
Chi Square ◽  
Serum Vitamin D

Background: Uterine atony is one of the causes of postpartum hemorrhage, resulting in increased maternal morbidity and mortality. Objective: To determine the association of low serum vitamin D level with uterine atony, among women delivering in a tertiary care hospital. Subjects and Methods: Study design: Case control Study. Setting: Gynae and Obstetrics department of Sheikh Zayed Medical College, Rahim Yar Khan. Duration: 1st January to 31st December, 2013. A total of 130 patients were recruited and grouped as A (Cases) including patients with uterine atony (100 patients) and group B (Controls) patients having no uterine atony (30 patients) after cesearean section or vaginal delivery and fulfilling the inclusion or exclusion criteria. The test for 25 OH vitamin D was performed on Elecsys 2010 Roche by using electrochemiluminescence technique. Oral informed consent was taken from all subjects and approval from institutional ethical committee was obtained. Chi square test was applied to compare atony and non atony groups in terms of presence or absence of vitamin D deficiency. The data was entered and analysed on SPSS version 17. Results: It was noted that those who have uterine atony 87% were having vitamin D deficiency or insufficiency as compared to 68% in group with no uterine atony. This difference was statistically significant. (p=0.02) so uterine atony was significantly associated with vitamin D deficiency or insufficiency. In atony group mean age was 25±4 years, gravida 2.64±1.2, gestational age, 37±1.2, blood loss 1032±400, and serum vitamin D level 15.9±6, ng/ml. In non atony group, group mean age was 26±3 years, gravida 2.7±1, gestational age, 38±.8, blood loss 309±92, and serum vitamin D level 23±9 ng/ml. The mean level of serum vitamin D level was significantly low (15.9±6 ng/ml) in atony group as compared to non atony group(23±9 ng/ml). Mean blood loss was significantly high (1032ml) in atony group as compared to non atony group (309ml). Conclusion: Our results revealed that low vitamin D level is strongly associated with uterine atony and hence is a risk factor for uterine atony.

scholarly journals Vitamin D: A Silent Cofactor for Allergic Rhinitis

2019 ◽  
Vol 27 (2) ◽  
pp. 107-112
Author(s):  
Rabi Hembrom ◽  
Somnath Patra ◽  
Rupam Sinha ◽  
Indranil Sen ◽  
Satadal Mandal ◽  
...  
Keyword(s):  
Vitamin D ◽  
Allergic Rhinitis ◽  
Tertiary Care ◽  
Serum Vitamin ◽  
Blood Eosinophil ◽  
Cell Mediated Immunity ◽  
Care Hospital ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Low Serum

Introduction   Allergic rhinitis affects around 50% of atopies in India. Vitamin D is related to both humoral and cell mediated immunity and its receptors are found in inflammatory mediators. This study was conducted to assess any possible association between Allergic rhinitis and serum Vitamin D. Materials and Methods A cross sectional study was conducted amongst 41patients with Allergic rhinitis as per ARIA guidelines attending the Otolaryngology outpatient Department of a peripheral tertiary care hospital. Vitamin D levels were assessed in patients with allergic rhinitis in terms of serum Ig-E level and absolute blood eosinophil count (ABEC). Results Among 41 patients, 31 patients (75.6%) had deficiency of vitamin D with mean Vitamin D level of 14.87±1.56ng/ml (normal vitamin D level-30-100ng/ml and low <20ng/ml), mean serum Ig-E level was 1040±303.83Iu/ml (normal-1.90-170 IU/ml by CLIA method) and mean ABEC 1226.77±397.89 (normal-30-350/ml). Conclusion Low serum Vitamin D is common in Allergic rhinitis patients. Low serum Vitamin D seems to be a significant cofactor in aetiopathogenesis of Allergic rhinitis in most of the cases.

scholarly journals Correlation of Vitamin D Status with Lipid Profile of Outpatient Department Attendees - A Cross Sectional Study in a Rural Tertiary Care Hospital of North Bengal, India

2021 ◽  
Vol 10 (35) ◽  
pp. 3012-3016
Author(s):  
Ritam Banerjee ◽  
Sandipan Datta ◽  
Arup Jyoti Rout
Keyword(s):  
Vitamin D ◽  
Lipid Profile ◽  
Indian Subcontinent ◽  
Tertiary Care ◽  
Serum Vitamin ◽  
Care Hospital ◽  
Vitamin D Status ◽  
Multinomial Regression ◽  
Serum Vitamin D ◽  
North Bengal

BACKGROUND Deficient or insufficient vitamin D status is found as a major chunk amongst all age groups all over the Indian subcontinent. Low levels of serum 25 (OH) D are associated with atherogenic lipid profile, and the resultant dyslipidemia is an important risk factor for cardiovascular disease and other atherosclerotic disorders in adults. As, not much literature was available on the deficiency of vitamin D and its effects, in the North Bengal region of West Bengal, India, this study was done to find out the association between vitamin D status and lipid profile of the participants and predict the risk of dislipidaemia with changes in vitamin D status. METHODS 430 medicine OPD attendees were selected for the study, interviewed after taking consent, blood parameters were examined and collected data were analysed for correlation and multinomial regression using SPSS v.25. RESULTS The mean value and standard deviation of serum 25 (OH) D level was found to be 21.53 ± 7.06 ng / ml. 35 % of vitamin D deficient subjects were found to be dyslipidemic. A negative correlation was observed between vitamin D status and total cholesterol & LDL status. While vitamin D status changed from “Sufficient” to “Deficient”, the chance of dyslipidemia increased by approximately 4.6 times. CONCLUSIONS Serum vitamin D influences largely the lipid profile of the study population. KEY WORDS Vitamin D, Serum 25 (OH) D, Dyslipidaemia, Cholesterol

scholarly journals VITAMIN D AND HSCRP LEVELS AMONG INSULIN RESISTANT PATIENTS IN A TERTIARY CARE HOSPITAL AT KOLKATA.

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Kaushik Kar ◽  
Satwika Sinha
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Tertiary Care ◽  
Serum Vitamin ◽  
High Sensitivity ◽  
Model Assessment ◽  
Care Hospital ◽  
Serum Vitamin D ◽  
Insulin Resistant ◽  
Homeostatic Model Assessment

Vitamin D deficiency probably takes a part in the development of insulin resistance. Insulin resistance also markedly affects the obese population. High-sensitivity C-reactive protein is a sensitive marker of subclinical inflammation and strongly predicts increased risks of insulin resistance. In this study, 123 obese persons were selected, and homeostatic model assessment (HOMA-IR) was measured in them. Serum Vitamin D and hsCRP were also measured in all participants. Among participants with HOMA-IR >2.7, significantly higher BMI, serum hsCRP and lower vitamin D were observed; Keywords: Obesity, BMI, HOMA-IR, Vitamin D, hsCRP.

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