scholarly journals Prevalence of Conventional Risk Factors and Lipid Profiles of Patients with First Day of Acute Coronary Syndrome Admitted in CCU of Gandaki Medical College Teaching Hospital, Pokhara, Nepal

2017 ◽  
Vol 9 (2) ◽  
pp. 13-16
Author(s):  
Gopi Prasad Hirachan ◽  
R Hirachan ◽  
BB Thapa ◽  
KB Thapa
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Lipid Profile ◽  
College Teaching ◽  
Medical College ◽  
Coronary Syndrome ◽  
Number Of Patients ◽  
History Of ◽  
Time Of Admission ◽  
Conventional Risk Factors

Background: Out of the total number of patients admitted in coronary care unit (CCU) with acute coronary syndrome (ACS), 75 - 85% presented with conventional risk factors. On the other hand, lipid profile modification after a cardiovascular event related to acute coronary syndrome has also been recognized. But there are controversies regarding the temporary changes in lipid profile after ACS. In our country, there are limited studies about the basal characteristics of lipid profile and the variability of its components after an ACS.Objectives: 1) To analyze the changes in lipoprotein levels in a group of patients hospitalized with ACS. 2) To describe the basal lipid profile. 3) To find out the prevalence of conventional risk factors of ACS patients.Methods: A total of 300 patients with the diagnosis of ACS were studied and the presence of conventional risk factors including smoking, hypertension, dyslipidemia and diabetes were recorded. In addition, we also analyzed the lipid profile within the first 24 hours of admission and body mass index (BMI) of all the patients included in the study.Results: Among a total of 300 patients, the mean age of men was 45 – 75 years and women 50 – 65 years. There were 47.5% patients with non-STEMI and 52.5% with ST-elevated myocardial infaraction (STEMI). In patients with BMI <24, 23.9% were males and 32.2% females; in patients with BMI 25 - 29, 55.4% were males and 48.7% females and in patients with BMI >30, 20.7% were males and 19.1% females. Among the study population, prior myocardial infaraction (MI) was seen in 29%, prior CABG in 4.2% and 10.5% had family history of CAD. In this study, diabetes and dyslipidemia were more in STEMI whereas dyslipidemia was common in non-STEMI. Among the conventional risk factors, smoking and hypertension were more common in STEMI in both men and women.Conclusions: In all patients admitted in CCU, basal lipid profile should be evaluated at the time of admission for choosing the most adequate treatment.Journal of Gandaki Medical College Volume, 09, Number 2, July December  2016, page: 13-16

scholarly journals Metabolic Risk Factors and Outcomes in Acute Coronary Syndrome

2020 ◽  
pp. 46-50
Author(s):  
Ritu Attri ◽  
Harsimran Kaur ◽  
Raminderpal Singh Sibia ◽  
Mandip Singh Bhatia
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Positive Family History ◽  
Developed Countries ◽  
P Value ◽  
Health Crisis ◽  
Female Ratio ◽  
Medical College ◽  
Coronary Syndrome ◽  
History Of

Introduction: CAD is the most common cause of mortality in India. It is a common multifarious public health crisis today and a leading cause of morbidity and mortality in both developing and developed countries. Hence, understanding the predominant risk factors among the Indian population is important. Materials and Methods: This was a hospital based age and sex matched case control study, carried out at Government Medical College and Rajindra Hospital Patiala. A total of 100 patients of Acute coronary syndrome were studied. Patients and controls were enquired about  the presence of cardiometabolic risk factors and the significance of association of these risk factors with the occurrence of Acute coronary syndrome was given by p value of  <0.05. Results: Majority of the cases were in the age group 61-70 years (32%) with male to female ratio  of 1.25:1. Significant association was found between ACS and risk factors like smoking, positive family history of IHD, hypertension, diabetes, dyslipidemia, waist hip ratio and body mass index. Overall, most common outcome of ACS in the present study was NSTEMI (45%) followed by STEMI (35%) followed by Unstable angina (20%). Conclusion: Significant association was found between smoking and occurrence of STEMI and significant association was found between Hypertension and occurrence of NSTEMI.

scholarly journals Prevalence of Conventional Risk Factors in Acute Coronary Syndrome Patients in Eastern Part of Nepal

2017 ◽  
Vol 6 (1) ◽  
pp. 48-55
Author(s):  
Rajesh Nepal ◽  
Madhav Bista ◽  
Abdul Khaliq Monib ◽  
Manoj Kumar Choudhary ◽  
Aakriti Bhattarai
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Culprit Lesion ◽  
Medical College ◽  
Coronary Syndrome ◽  
Risk Factor Reduction ◽  
High Prevalence ◽  
Study Population ◽  
Artery Disease ◽  
Conventional Risk Factors

Background: Smoking, diabetes mellitus, hypertension and dyslipidemia are known as conventional risk factors of coronary artery disease (CAD) and the prevalence of it varies across populations. There is paucity of data in our country about the prevalence of risk factors for acute coronary syndrome (ACS). This study aims to assess the prevalence of these conventional risk factors in patients who were admitted in Nobel medical college, with the diagnosis of ACS.Material & Methods: In this observational study, we enrolled 102 patients diagnosed as ACS with stenosis ≥50% of any epicardial arteries as shown on angiography admitted in Nobel Medical College between September 2015 to March 2017 and evaluate the prevalence of conventional risk factors. In addition, we analyzed the lipid profiles within 24 hour of the event.Results: Mean age of the patients was 59 years. Two third (66.7%) of the patients were male. Left anterior descending artery (43.13%) was the most common culprit lesion followed by RCA in 35.29%. Dyslipidemia was present in 73.5%, hypertension in 46.1%, smoking in 38.2% and diabetes in 37.3%. Prevalence of hypertension, diabetes and dyslipidemia was similar among male and female. Smoking (44.1%vs26.5%) was more common in male (P=<0.05). TG ≥150 mg/dl was seen in 52% study population and higher level of TG was seen in younger population ≤45 years compared to ≥45 years old (p=0.013).Conclusion: Present study showed high prevalence of hypertension, smoking, diabetes and dyslipidemia in patients with ACS, suggesting the need of aggressive risk factor reduction in general population. Journal of Nobel Medical CollegeVolume 6, Number 1, Issue 10 (January-June, 2017), page: 48-55

Peripheral artery disease in outpatients with a recent history of acute coronary syndrome or at high atherothrombotic risk

Vascular ◽  
2020 ◽  
pp. 170853812093892 ◽  
Author(s):  
Carlos Cantú-Brito ◽  
Erwin Chiquete ◽  
Javier F Antezana-Castro ◽  
Liz Toapanta-Yanchapaxi ◽  
Ana Ochoa-Guzmán ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Peripheral Artery Disease ◽  
Case Fatality ◽  
Coronary Risk ◽  
Vascular Risk ◽  
Peripheral Artery ◽  
Coronary Syndrome ◽  
History Of ◽  
Artery Disease

Objectives The frequency and implications of peripheral artery disease (PAD) in some risk groups are not entirely characterized in Latin America. We studied PAD prevalence, risk factors, and six-month outcomes in stable outpatients with a history of a recent acute coronary syndrome (ACS), or at high coronary risk. Methods We recruited 830 outpatients in 43 Mexican sites (median age: 64.8 years; 57.8% men). Inclusion criteria were age >18 years, and ACS within 30 days, or age <55 years plus ≥2 major vascular risk factors, or age ≥55 years plus ≥1 vascular risk factors. Patients received standardized assessments at baseline and six-month follow-up for medical history, ankle-brachial index (ABI), and the Edinburgh Claudication Questionnaire (ECQ). Results ABI <0.8 was found in 10.5%, <0.9 in 22.5%, >1.3 in 4.8%, and >1.4 in 3.6%, without differences according to sex or selection criteria. Positive ECQ was found in 7.6%. ABI <0.9 was directly associated with age, diabetes, ACS, and chronic kidney disease, but inversely associated with BMI >27. The six-month case-fatality and atherothrombotic events rates were 1.6% and 3.6%, respectively. In patients with ABI <0.9 and ABI <0.8, the six-month case-fatality rates were 2.5% ( p =  0.27) and 5.4% ( p =  0.03), respectively. In a Cox proportional-hazards model, baseline factors associated with death were age ≥65, ABI <0.8, and ACS. Conclusions Subclinical PAD is more common than symptomatic claudication in high-risk coronary outpatients. Low ABI is associated with reduced short-term survival in patients with recent ACS or at high coronary risk.

scholarly journals Association of Haemoglobin and C-Reactive Protein level with Different Risk Factors among Acute Coronary Syndrome Patients

2019 ◽  
Vol 5 (2) ◽  
pp. 156-160
Author(s):  
Md Mahboob Morshed ◽  
Md Joynul Islam ◽  
ATM Ashadullah ◽  
Khondker Shaheed Hussain ◽  
Mohammad Ahtashamul Haque
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Reactive Protein ◽  
Coronary Syndrome ◽  
Group 4 ◽  
History Of ◽  
Study Population ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Background: Different risk factors may be related with the haemoglobin and CRP level among the acute coronary syndrome patients. Objective: The purpose of the present study was to see the association of haemoglobin and CRP level with different type of risk factors among the acute coronary syndrome patients. Methodology: This cross-sectional study was conducted in the Department of Cardiology at Mymensingh Medical College, Mymensingh, Bangladesh from December 2010 to November 2011 for a period of two (02) years. Patients of ACS who were presented within 12 hours of chest pain were included as study population. Study population were categorized in four groups according to the level of hemoglobin and C-reactive protein. Age, cardiovascular risks factor, history, family history of cardiovascular disease, treatment history and ECG were taken during admission. Blood sample was collected for baseline laboratory investigations like Troponin-I, Random Blood Sugar (RBS), Blood urea, Serum creatinine, lipid profile, Hemoglobin & CRP level. Sample were then send to standard laboratory/Biochemistry department of MMCH. Result: The mean age of the population was 52.18±8.88 years. Smoking was the highest percentage in Group 1 which was 54(50.0%) cases (P=0.001). Hypertension was found most common in group 1 (47.6%), Group 2 (33.3%), Group 3 (10.7%) and Group 4 (8.3%). Smoking (p=0.001) and hypertension (p=0.016) was found statistically significant. Diabetes was found in Group 1 (37.7%), Group 2 (43.5%), Group 3 (11.6%) and Group 4 (7.2%). Group 1 (50%) and Group 2 (50%) patients were dyslipidaemic. Family history of IHD was present group-1 (36.8%), Group 2 (44.7%), Group 3 (73.2%) and Group 4 (53%). Among the smoker patient 65.6% cases had CRP level ˃12 mg/l; 39.8% cases had CRP level ˂12mg/L. Among the nonsmoker 34.4% cases had CRP level ˃12mg/l and 60.2% cases had CRP level ˂12mg/L. The finding was statistically significant. Conclusion: In conclusion haemoglobin and CRP level is associated with different type of risk factors among the acute coronary syndrome patients. Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 156-160

scholarly journals Specific Features of the Course of Acute Coronary Syndrome in Patients with Newly Developed Atrial Fibrillation in Clinical Practice According to the Data of the Register of Acute Coronary Syndrome

Kardiologiia ◽  
2019 ◽  
Vol 59 (7) ◽  
pp. 19-25
Author(s):  
Z. G. Tatarintseva ◽  
E. D. Kosmacheva ◽  
S. A. Raff ◽  
S. V. Kruchinova ◽  
V. A. Porkhanov
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Acute Coronary Syndrome ◽  
Clinical Practice ◽  
Hospital Discharge ◽  
Oral Anticoagulant Therapy ◽  
Inhospital Mortality ◽  
Thromboembolic Complications ◽  
Coronary Syndrome ◽  
Number Of Patients

Aim: to elucidate risk factors of development of atrial fibrillation (AF) in patients with acute coronary syndrome (ACS), and to assess of patient’s adherence to oral anticoagulant therapy (OAT) during 12 months after ACS episode according to the data of the Total ACS Registry for the Krasnodar Territory.Materials and methods. In this retrospective analysis we used Registry data on patients with ACS and concomitant AF, consecutively admitted to cardiological departments of the S.V. Ochapovsky Territorial Clinical Hospital from 20/11/2015 to 20/02/18. Number of patients in the analyzed group was 201 (52 with AF which first appeared in connection with the index ACS). Survivors after hospital discharge were contacted by telephone and at planned visits. The analysis included assessment of rates of the following outcomes: inhospital death, hemorrhagic and thromboembolic complications, prognostic efficacy of the CRISADE and HAS BLED scores, and expediency of prescription to patients with ACS and concomitant first AF episode of prolonged OAT after hospital discharge.Results. Demographic and anamnestic data of patients with the first AF attack at the background of ACS were like those of patients with other types of AF. This group of patients was characterized by more severe course of the disease, but this produced no impact on inhospital mortality and rate of complications, as well as on mortality for 12 months after hospital discharge.Conclusion. The results of this analysis are important for understanding distinctive characteristics of patients with AF first developed during ACS.

scholarly journals Epidemiology and risk factors of patients with types of acute coronary syndrome presenting to a tertiary care hospital in Sri Lanka

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Udaya Ralapanawa ◽  
Pallegoda Vithanage Ranjith Kumarasiri ◽  
Kushalee Poornima Jayawickreme ◽  
Prabashini Kumarihamy ◽  
Yapa Wijeratne ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Sri Lanka ◽  
Unstable Angina ◽  
Stable Angina ◽  
Strong Association ◽  
Coronary Syndrome ◽  
History Of ◽  
St Elevation

Abstract Background Acute Coronary Syndrome (ACS) is one of the leading causes of death worldwide and studies have shown higher mortality rates and premature death in South Asian countries. The occurrence and effect of risk factors differ by type ofACS.Epidemiological studies in the Sri Lankan population are limited. Methods This is a cross sectional descriptive study conducted at the Teaching Hospital Peradeniya, Sri Lanka among patients presenting with ACS. Data was collected by an interviewer administered structured questionnaire and epidemiological patterns and risk factors were analyzed. Results The sample of 300 patients had a mean age of 61.3+/− 12.6 and male sex showed higher association with all three type of ACS compared to female with a P value of 0.001. This study showed higher mean age of 62.2 ± 11.4 years amongst unstable angina (UA) patients and 61.9 ± 14.5 years amongst non ST elevation myocardial infarction (NSTEMI) patients compared to 59.2 ± 11.2 years for ST elevation myocardial infarction (STEMI) patients with no significant statistical difference (P = 0.246). Approximately 55.8% STEMI patients, 39.8% UA and 35.5% NSTEMI patients were smokers indicating a significant association between smoking and STEMI (P = 0.017). Nearly 54.5% STEMI, 35.4% UA and 32.7% NSTEMI patients consumed alcohol and there was a very strong association between alcohol consumption and STEMI (P = 0.006). Almost 51.8% NSTEMI patients, 47.8% UA patients and 29.9% STEMI patients had hypertension(HT) (P = 0.008) indicating significant association of HT with UA and NSTEMI. About 33.6% UA patients and 30.0% NSTEMI patients had DM whilst only 22.1% of STEMI patients had DM of no significance (p = 0.225). Around 15.0% patients with UA, 25.5% with NSTEMI and 11.7% with STEMI had dyslipidemia (P = 0.032). There was a very strong association between a past history of ACS or stable angina with NSTEMI and UA (P = 0.001). Conclusion Smoking and alcohol abuse are significantly associated with STEMI.Patients with NSTEMI or Unstable Angina had higher rates of hypertension and were more likely to have a history of ACS or stable angina than STEMI patients. Patients with NSTEMI were more likely than patients with STEMI or UA to have dyslipidemia.

scholarly journals A Study on Clinical Profile, Risk Factors, Angiographic Profile and Short-Term Mortality of Acute Coronary Syndrome in Smokers vs Non Smokers

2020 ◽  
Vol 9 (2) ◽  
pp. 1-5
Author(s):  
B V Narayana Reddy ◽  
Hemasundar Korrapati ◽  
Supraja Chegireddy
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Care Practice ◽  
Medical College ◽  
Coronary Syndrome ◽  
Short Term Mortality ◽  
Prevalence Of Obesity ◽  
Coronary Syndromes ◽  
Socio Demographic Factors ◽  
A Prospective Study

Background: Smoking has long been positively associated with the development and progression of coronary heart disease. However, lon- gitudinal cohort studies evaluating smoking habits among cardiac patients as well as the role of socio-demographic factors determining such behaviours are scarce and have been focused on primary care practice. Prevalence of acute coronary syndrome in young individuals is increasing progressively. Previous studies have focused on the analysis of risk factors and to some extent coronary angiographic profile in smokers         vs non-smokers patients with acute coronary syndrome. The aim of the study is to study the acute coronary syndrome in smokers versus non-smokers and to analyse with respect to baseline characteristics. Subjects and Methods: It was a prospective study conducted at Department of Cardiology, Katuri Medical College & Hospital Guntur. Results: In the present study, Acute coronary syndrome occurred seven years earlier in smokers compared with non-smokers (p<0.05) Smokers were frequently male subjects compared with non-smokers (p<0.001) Smokers had a lower prevalence of Diabetes compared with non-smokers (p<0.001) Smokers had a higher prevalence of Obesity compared with non-smokers (p<0.001). Smokers presented with more acute infarctions and less Unstable angina compared with non-smokers (P<0.001). Conclusion: In  the present study, significant differences were observed in coronary risk factor profile between smokers and non-smokers patients with STEMI and NSTEMI/UA. Larger studies will be required to establish specific associations between presentation of acute coronary syndromes and angiographic profiles in smokers.

scholarly journals INTERACTION OF TOBACCO ABUSE WITH OTHER CONVENTIONAL RISK FACTORS OF CARDIOVASCULAR RISK - SYNERGISTIC IMPACT OR AN INDEPENDENT MENACE?

2022 ◽  
Vol 54 (4) ◽  
pp. 352-356
Author(s):  
Arslan Masood ◽  
Noor Dastgir ◽  
Inam Ur Rehman ◽  
Junaid Rehman ◽  
Aleena Khan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Total Duration ◽  
Tobacco Consumption ◽  
Urban Residents ◽  
Coronary Syndrome ◽  
Tobacco Addiction ◽  
Tobacco Abuse ◽  
History Of ◽  
Conventional Risk Factors

Objectives: To determine the prevalence, patterns and behavioural attributes of tobacco abuse in patients of acute coronary syndrome (ACS). Furthermore, to assess the interaction of tobacco abuse with other conventional risk factors of cardiovascular disease (CVD). Methodology: This observational study included 230 consecutive patients with ACS. Data was collected regarding total duration and extent of tobacco consumption, “tobacco addiction” and various behavioural patterns related to it. Risk factors profile was acquired for hypertension, diabetes, obesity, family history of premature CVD and dyslipidemia. Odds ratios (OR) with 95% confidence intervals (CI) for these risk factors were calculated for tobacco abusers compared to non-abusers. Results: Among the study population, 63(27.4%) were active tobacco users. Urban residents had lesser odds of being tobacco abusers compared to non-urban residents (0.49, [0.27 – 0.89]). Tobacco abusers had a lower prevalence of hypertension compared to non-abusers (0.44 [0.24 – 0.81]). A similar trend was observed for diabetes, obesity and dyslipidemia, however, the differences could not reach significance thresholds. Cigarette smoking was the commonest mode of tobacco consumption (90.5%). “Tobacco addiction” could be attributed to 84.1% of abusers. Most (82.5%) were willing to give up tobacco abuse and 63.3% had already made attempts at quitting. Conclusion: About one-third of ACS patients were tobacco abusers with the majority being tobacco addicts. Tobacco abuse was observed to be independently implicated as a risk factor in ACS patients. Furthermore, tobacco abuse was inversely related to hypertension translating into a sub-multiplicative / additive impact of hypertension as a risk factor.

scholarly journals STUDY ON CONVENTIONAL RISK FACTORS IN ACUTE CORONARY SYNDROME

2016 ◽  
Vol 3 (2) ◽  
pp. 1-4 ◽  
Author(s):  
Prabin Khatri ◽  
Rabindra Simkhada
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Significant Positive Correlation ◽  
Medical Science ◽  
Medical Sciences ◽  
Positive Correlation ◽  
Coronary Syndrome ◽  
The Common ◽  
Diabetes And Obesity ◽  
Conventional Risk Factors

INTRODUCTION: Acute coronary syndrome is one of the common cardiovascular diseases. Smoking, dyslipidemia, hypertension, diabetes and obesity are conventional risk factors. Different studies have shown variable prevalence of these risk factors. This study was designed to see the prevalence of these risk factors in our setting and see their correlation with different types of acute coronary syndrome. MATERIAL AND METHOD: This was a hospital based observational study conducted at Universal College of Medical Science Teaching Hospital, Bhairahawa from September 2012 to August 2013. A total of 100 consecutive patients were enrolled after applying inclusion and exclusion criteria. RESULTS: Out of 100 study patients, 64% were male and 36% were female. Their age ranged from 30 years to 87 years with mean age of 60 ± 12.90 year. Hypertension was present in 64%, 62% were dyslipidemic. Similarly 39% were smoker and 19% had diabetes. Sex (p=0.01) and hypertension (p<.01) showed significant positive correlation with type of acute coronary syndrome.CONCLUSION: Hypertension was the most prevalent risk factor for the occurrence of acute coronary syndrome. Diabetes mellitus, smoking, and dyslipidemia was also present in considerable numbers. Gender and hypertension showed significant positive correlation with type of Acute Coronary Syndrome.Journal of Universal College of Medical Sciences (2015) Vol.3(2): 1-4 

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