scholarly journals Urinary Tract Infection and Antibiotic Susceptibility at Nepalgunj Medical College and Teaching Hospital, Kohalpur

2018 ◽  
Vol 14 (2) ◽  
pp. 34-37
Author(s):  
Binod Mahaseth ◽  
Madhuri Srivastava ◽  
C. R. Das ◽  
Durga Rawat

Introduction: In developing countries, urinary tract infections (UTIs) are one of the most commonly diagnosed diseases among the patient seeking medical service and are treated with empirical antibiotics which does not provides cure and causes resistance.Objective: To find out the incidence of urinary tract infections and antibiotics sensitivity pattern among bacterial pathogens isolated in patients attending Nepalgunj Medical College and Teaching Hospital, Kohalpur.Methodology: All patients (both male and female) were included in the study with the clinical suspicion of UTI . They had their urine culture done. Incidence of UTI and spectrum of pathogens with their sensitivity were recorded.Result: A total number of 1445 patients were clinically suspected for UT. They had their urine cultura and sensitivity done Total number of patients with culture positive was 391(27.05%). The majority of isolates were from female patients comprising of 314(80.3%) patients. The most common pathogenic microorganism isolated was E.coli (73.65%). Second most common organism was Klebsiella (19.9%), it was followed by Acinetobacter (3.5%), Enterobacter (3.06%), Pseudmonas and Proteus (0.76%) each, Staphylococcus (0.05%) salmonella (0.02%). The isolated microorganisms showed maximum sensitivity to Nitrofurantin and Amikacin. The isolated microorganism demonstrated resistance to cefpodoxime and Cefotaxime.Conclusion: Urinary tract infections is a commonly encountered case in general practice Females are more commonly affected than men. The microbial profile and the antibiotic sensitivity pattern must be taken into account while planning for the management. Regular supervision of the sensitivity pattern of pathogenic microorganism is mandatory for effective treatment.JNGMC, Vol. 14 No. 2 December 2016, Page: 34-37

2017 ◽  
Vol 2 (1) ◽  
pp. 134-137 ◽  
Author(s):  
Binita Pradhan ◽  
SB Pradhan

IntroductionIn developing countries, urinary tract infections (UTIs) are one of the most commonly diagnosed diseases among the patient seeking medical service and being treated with empirical antibiotics which causes resistance.ObjectiveTo find out the prevalence of urinary tract infection and sensitivity pattern of antibiotics among bacterial pathogens isolated in patients attending Kathmandu Medical College Teaching Hospital, Duwakot.MethodologyAll the patients with the clinical suspicion of UTI were sent for urine culture. Prevalence of UTI and urinary pathogens isolated with antimicrobial profile was correlated.ResultA total number of 1735 clinically suspected as UTI cases were sent for urine culture sensitivity. Total culture positive were 239 (13.8%). The majority of isolates were from female patients comprising 180 (75%). The most common pathogenic microorganism isolated was E.coli (79.1%). Second most common organism was Klebsiella (11.7%) followed by Citrobacter (3.34%) and Proteus (2.92%). The isolated microorganism showed maximum number of sensitivity with the antibiotics Ofloxacin and Ciprofloxacin. The isolated microorganism demonstrated resistance with Nalidixic Acid and Co-Trimoxazole. ConclusionUrinary tract infection is a commonly encountered case in general practice. Females are commonly affected than men. The microbiological profile and the antibiotic sensitivity pattern while initiating empirical treatment must be taken into account while planning for the management. Regular supervision of the sensitivity pattern of pathogenic microorganism is mandatory for effective treatment.Birat Journal of Health Sciences Vol.2/No.1/Issue 2/ Jan - April 2017, Page: 134-137


2021 ◽  
Vol 8 (10) ◽  
pp. 5692-5697
Author(s):  
Dr. Digbijay Kumar Thakur ◽  
Dr. Rameshwar Mahaseth ◽  
Dr. Shambhu Kumar Sah

Background: Urinary tract infections are most common bacterial infection in routine clinical practice. It is also most common nosocomial infection in many hospitals. Antibiotics are usually given empirically before urine culture reports available and treatment failure rate used to be significantly high. Study of causative agents and their antimicrobial sensitivity pattern are important factors helping formulating antibiotic policy. Generally, most common uropathogene is Escherichia Coli. Tertiary care hospitals, catering of already partially treated or mal treated patients as major chunk, may have varying etiologies and different sensitivity patterns. Objective: To study the culture and sensitivity patterns of urinary tract infections in patients presenting with urinary symptoms in local hospitals. Study design: A cross sectional study Materials and methods: Study was conducted at Madanta Research Clinic Private Limited from 12th march 021 to 12th September 021. Urine from cases suspected to have symptoms suggestive of UTI were send for bacteriological culture and sensitivity. Demographic profiles of each participant along with pathogen isolated, culture sensitivity pattern was documented. Data analysis was done in IBM spss 25. Results: A total 200 samples were selected for bacteriological culture and sensitivity out of which 32% were male and 68% were female. Around 50% of participants were in age group 20-40. There was no growth in 64% sample. Among positive samples (36%), E. coli (most common) was detected in 91.66%, Klebsiella was detected in 6.94%. Gentamicin, Amikacin and Nitrofurantoin were most common antibiotics sensitive to organisms in culture and Cephalosporins group of antibiotics are commonly resistant. Conclusions: coli is the most common organism isolated in urine culture in our region Janakpur. Cephalosporins are resistant in majority of cases where as Aminoglycosides like Amikacin, Gentamicin and Nitrofurantoin are found to be highly sensitive in most of positive cases.


2015 ◽  
Vol 14 (1) ◽  
pp. 70-74
Author(s):  
Shahin Sultana ◽  
Marium Khatun ◽  
Md Khoybar Ali ◽  
Nurunnahar Mawla ◽  
Nayareen Akhter

Background: Urinary tract infections (UTI), being the most common infections diagnosed in community and hospital, are to be treated scrupulously considering the type of infecting organism and its antibiotic sensitivity and resistance pattern. Aims and objectives: The aim of the present study was to observe the antibiotic sensitivity pattern of isolated uropathogens from urine samples of patients attending at Shahabuddin Medical College & Hospital, Dhaka, during the period of July 2008 to June 2009. Result: A total of 555 urine samples were studied; of which 84 (15.13%) were culture positive. Among 84 culture positive cases, 84 isolates were identified. Among the isolates, E.coli was the most predominant 61 (62.88%) followed by Enterococci 11 (11.34%), proteus 4 (4.13%) and Pseudomonas 3 (3.09%). Whereas Staphylococcus saprophyticus and Klebsiella showed frequency rate of 2 (2.06%) for each. However Gram positive cocci showed lowest frequency rate of 1 (1.03%). All of the isolates were sensitive to Netilmicin. The majority of isolates were sensitive to Imipenam (92.3%) followed by Amikacin (91.1%), Meropenam (83.3 %), Tetracycline (70%). Sensitivity & resistance rate were same (50%) in Vancomycin & Cefodoxime. Where complete (100%) resistance was shown to Ampicillin, Azithromycin and Cefoxitin. However all isolates were poorly sensitive to cotrimoxazole (35.7%), ciprofloxacin (43%) and nitrofurantoin (44.8%). Conclusion: So, routine urine culture and susceptibility before therapy should be encouraged and periodic evaluation of predominant organisms and their antimicrobial susceptibility pattern should be studied for appropriate selection of antibiotic for effective management of UTI cases.DOI: http://dx.doi.org/10.3329/bjms.v14i1.21562 Bangladesh Journal of Medical Science Vol.14(1) 2015 p.70-74


Med Phoenix ◽  
2020 ◽  
Vol 5 (1) ◽  
pp. 40-45
Author(s):  
Sagar Ghimire ◽  
Sanjay Paudel ◽  
Shahrukh KC ◽  
Pragya Gautam ◽  
Vikash Paudel

Background: Urinary tract infections (UTIs) are one of the most common infectious conditions seeking treatment. There are varieties of microorganisms associated. The bacteriological investigations are incomplete without antibiotic sensitivity test of the isolate. Our aim is to determine age and sex distribution of UTI, bacteriological profile, and antibiotic sensitivity pattern of the organisms. Materials and Methods: A retrospective cross-sectional observational study of records of patients with clinically suspected UTI from Kartik 2076 to Magh 2076 was conducted at National Medical College and Teaching Hospital (NMCTH). It included both inpatient and OPD visit patients who submitted their clean-catch midstream urine sample for culture and antibiotic sensitivity at Microbiology lab of NMCTH. Result: Out of 385 patients, 103 (26.75%) showed bacterial growth. Escherichia coli (47.58 %) was the most common organism followed by Staphylococcus sps. (18.45%) and Klebsiella sps.(17.47%) respectively. There was female dominance (62.13%) but male were predominantly affected in children and older population. The most common age group for UTI was 21-30 years (mean age 25 years) and females were more affected than males. The most common pathogen was Escherichia coli, followed by Staphylococcal sps. and Klebsiella. All the organisms showed best sensitivity to tigecycline (100%). Conclusion: This study highlights the common pathogens causing UTI and their antibiotic sensitivity patterns which could help clinicians in starting rational empirical antibiotic therapy for such patients while awaiting urine culture reports.   


2018 ◽  
Vol 4 (2) ◽  
pp. 63
Author(s):  
Binod Chapagain ◽  
Parshal Bhandari ◽  
Binod Aryal

The main purpose of this study was to find out the causative agents of urinary tract infections (UTI) and their culture and antibiotic sensitivity in patients visiting Tribhuvan University and Teaching Hospital (TUTH). A retrospective study conducted among 155 patients, aged from 25-50 years with culture-positive UTI, who visited TUTH from 1st April 2017 to 30th September 2017. A culture of midstream urine was done to find out causative agents and their antibiotic sensitivity performed. Data were evaluated using Microsoft Excel 2016. Female were more affected than males. Escherichia coli (E. coli) was the most common microbes causing UTI in 53% patients. Most of the isolates on culture were Multi-Drug Resistant (MDR) strains to comprise 52%. Of the total gram-negative organisms, 33.9% were Extended Spectrum β-lactamase (ESBL) producers, and 3.57% were Metallo β-lactamase (MBL) producers. 29.41% of Staphylococcus were resistant to methicillin. E.coli is the most common organism causing UTI among adults. Multidrug-resistant has appeared alarming with resistant to most of the first line antibiotics.


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