scholarly journals Epidemiological and Bacteriological Profile of Urinary Tract Infection and the Antibiotic Sensitivity Pattern of Causative Organisms in National Medical College and Teaching Hospital - A Retrospective Cross-Sectional Study

Med Phoenix ◽  
2020 ◽  
Vol 5 (1) ◽  
pp. 40-45
Author(s):  
Sagar Ghimire ◽  
Sanjay Paudel ◽  
Shahrukh KC ◽  
Pragya Gautam ◽  
Vikash Paudel

Background: Urinary tract infections (UTIs) are one of the most common infectious conditions seeking treatment. There are varieties of microorganisms associated. The bacteriological investigations are incomplete without antibiotic sensitivity test of the isolate. Our aim is to determine age and sex distribution of UTI, bacteriological profile, and antibiotic sensitivity pattern of the organisms. Materials and Methods: A retrospective cross-sectional observational study of records of patients with clinically suspected UTI from Kartik 2076 to Magh 2076 was conducted at National Medical College and Teaching Hospital (NMCTH). It included both inpatient and OPD visit patients who submitted their clean-catch midstream urine sample for culture and antibiotic sensitivity at Microbiology lab of NMCTH. Result: Out of 385 patients, 103 (26.75%) showed bacterial growth. Escherichia coli (47.58 %) was the most common organism followed by Staphylococcus sps. (18.45%) and Klebsiella sps.(17.47%) respectively. There was female dominance (62.13%) but male were predominantly affected in children and older population. The most common age group for UTI was 21-30 years (mean age 25 years) and females were more affected than males. The most common pathogen was Escherichia coli, followed by Staphylococcal sps. and Klebsiella. All the organisms showed best sensitivity to tigecycline (100%). Conclusion: This study highlights the common pathogens causing UTI and their antibiotic sensitivity patterns which could help clinicians in starting rational empirical antibiotic therapy for such patients while awaiting urine culture reports.   

2012 ◽  
Vol 18 (1) ◽  
pp. 4-6
Author(s):  
Md Badrul Islam ◽  
Munir Hasan

Urinary tract infection is the most common infection causing illness in children and adults. This study was aimed to identify the uropathogens and their antibiotic sensitivity pattern. This study was done in Microbiology Department at Dhaka National Medical College & Hospital, Dhaka, during January, 2010 to December, 2010. A total of 1874 samples of urine were collected from suspected cases of urinary tract infections, from Dhaka National Medical College & Hospital. Among them, 290 (15.48%) showed significant bacterial growth. The most common uropathogens isolated were E.coli 229 (78.97%), Staph. saphrophyticus 15 (5.18%), Coliform 12 (4.13%), Klebsiella spp. 10 (3.44%), Enteococous 10 (3.44%), Staph. aureus 05 (1.72%), Streptococcus spp. 05 (1.72%) and Pseudomonas spp. 04 (1.38%). E.coli is the most common urupathogen and showed sensitivity pattern to Imipenem 84.28%, Amikacin 83.41%, Nitrofurantoin 73.80%, Gentamycin 66.88%, Ciprofloxacin 41.48%, Doxycycline 36.30%, Ceftazidime 34.50%, Ceftriaxone 33.62%, Cefexime 31.0%, Cotrimoxazole 32.31%, Nalidixic acid 24.01%, Cephradine 17.47% and Ampicillin 11.35%. DOI: http://dx.doi.org/10.3329/jdnmch.v18i1.12223 J. Dhaka National Med. Coll. Hos. 2012; 18 (01): 4-6


2020 ◽  
Vol 17 (2) ◽  
pp. 42-45
Author(s):  
Md. Badrul Islam ◽  
Md. Abdullah Yusuf ◽  
Munir Hassan ◽  
Shimul Akter

Background: Urinary tract infection is the most common infection occurs in both male and female. Objective: This study was aimed to identify the uropathogens and their antimicrobial sensitivity pattern. Methodology: This study was carried out in the Department of Microbiology at Dhaka National Medical College & Hospital, Dhaka from January 2018 to December 2018. Result: A total of 1686 samples of urine were collected from suspected cases of urinary tract infections from Dhaka National Medical College & Hospital. Among them, 292 (17.32%) specimens showed significant bacterial growth. The most common uropathogens isolated were Escherichia coli. Conclusion: In conclusion Gram negative bacteria is the commonest uropathogens isolated. Journal of Science Foundation July 2019;17(2):42-45


2013 ◽  
Vol 5 (2) ◽  
pp. 23-26
Author(s):  
Sanya Tahmina Jhora ◽  
Shikha Paul ◽  
Bilkis Ara Begum ◽  
Abul Quashem Chowdhury

Urinary tract infections (UTIs) are one of the most common infectious diseases & an important cause of morbidity in general population. More than 90% of all uncomplicated UTI s are caused by Esch. coli infection. The study was carried out in Department of Microbiology of Sir Salimullah Medical College & Mitford Hospital (SSMC& MH) Dhaka from October 2002 to September 2003. A total of 749 urine samples were studied of which 414 (55.27) showed significant growth. Among the 414 isolates, E sch. coli was the most predominant (82.61%) organism. Esch. coli was highly sensitive to Imipenem (95.02%) followed by Ceftriaxone (86.84%), Cefuroxime (67.54%), Gentamicin (66.08%), and Ceftazidime (55.84%) respectively. Low sensitivity patterns were shown against Nitrofurantoin (44.73%) & Ciprofloxacin (40.64%). The sensitivity to other antibiotics varied from 23.39% to as low as 2.63%. The aim of the present study was to observe the antibiotic sensitivity pattern of isolated Esch. coli from urine samples of patients admitted in inpatient department or visited the out patient department of Sir Salimullah Medical College & Mitford Hospital (SSMC& MH) Dhaka.DOI: http://dx.doi.org/10.3329/bjmm.v5i2.16934 Bangladesh J Med Microbiol 2011; 05 (02): 23-26


2018 ◽  
Vol 14 (2) ◽  
pp. 34-37
Author(s):  
Binod Mahaseth ◽  
Madhuri Srivastava ◽  
C. R. Das ◽  
Durga Rawat

Introduction: In developing countries, urinary tract infections (UTIs) are one of the most commonly diagnosed diseases among the patient seeking medical service and are treated with empirical antibiotics which does not provides cure and causes resistance.Objective: To find out the incidence of urinary tract infections and antibiotics sensitivity pattern among bacterial pathogens isolated in patients attending Nepalgunj Medical College and Teaching Hospital, Kohalpur.Methodology: All patients (both male and female) were included in the study with the clinical suspicion of UTI . They had their urine culture done. Incidence of UTI and spectrum of pathogens with their sensitivity were recorded.Result: A total number of 1445 patients were clinically suspected for UT. They had their urine cultura and sensitivity done Total number of patients with culture positive was 391(27.05%). The majority of isolates were from female patients comprising of 314(80.3%) patients. The most common pathogenic microorganism isolated was E.coli (73.65%). Second most common organism was Klebsiella (19.9%), it was followed by Acinetobacter (3.5%), Enterobacter (3.06%), Pseudmonas and Proteus (0.76%) each, Staphylococcus (0.05%) salmonella (0.02%). The isolated microorganisms showed maximum sensitivity to Nitrofurantin and Amikacin. The isolated microorganism demonstrated resistance to cefpodoxime and Cefotaxime.Conclusion: Urinary tract infections is a commonly encountered case in general practice Females are more commonly affected than men. The microbial profile and the antibiotic sensitivity pattern must be taken into account while planning for the management. Regular supervision of the sensitivity pattern of pathogenic microorganism is mandatory for effective treatment.JNGMC, Vol. 14 No. 2 December 2016, Page: 34-37


Med Phoenix ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 14-18
Author(s):  
Smita Singh ◽  
Deependra Prasad Sarraf ◽  
Prabin Singh ◽  
Pragati Poudyel

Introduction: Pharmacovigilance helps in the detection and prevention of adverse effects of drugs. For the effectiveness of this program, health care professionals should report adverse drug reactions (ADRs) considering it as their moral and professional obligation. The objective of the study was to assess the knowledge, attitude, and practices (KAP) of the doctors towards ADRs and pharmacovigilance in  National Medical College Teaching Hospital (NMCTH), a tertiary care teaching hospital situated in the Narayani zone. Materials and Methods: A cross-sectional study was carried out using a self-administered questionnaire consisting of four parts; first part included a demographic profile of participants, the second part consisted of ten questions for the assessment of the knowledge about pharmacovigilance, third part comprised of six questions on attitude and fourth part consisted of five questions on practice. The results were depicted in the form of percentages for each KAPs questionnaire.   Results: The response rate of participants was 85.16%. Pharmacovigilance was correctly defined by 52%. Department of drug administration was responsible for monitoring ADRs in Nepal was correctly given by 80%. Only 8% had reported ADRs, although 62% had encountered an ADR in their clinical practice. Conclusion: The doctors at NMCTH had a poor KAP towards pharmacovigilance and educational intervention is needed for the proper functioning of this program.


2013 ◽  
Vol 1 (1) ◽  
pp. 48-52
Author(s):  
S Shrestha ◽  
B Shakya ◽  
P Shrestha

Background and Objectives: Mycobacterial disease continues to cause high morbidity and mortality and is a major public health problem in Nepal. Bacteriological examination of sputum is the cornerstone in the diagnosis of pulmonary tuberculosis in the developing world. This prospective study was carried out with an objective to evaluate the prevalence of pulmonary tuberculosis among the patients visiting National Medical College Teaching Hospital by Ziehl- Neelsen (Zn) staining microscopy. Material and Methods: The study was cross-sectional study. Three consecutive early morning sputum collected from 626 patients were subjected to Zn staining and observed under oil immersion. Results: Among 626 patients, 85 (13.57%) were found to be Acid fast positive by Zn staining microscopy. Of total suspected patients,16.0% of male and 8.7% of female were infected, common among 41-60 years group (17.2%) followed by 21-40 years (12.6%) and multibacillary cases was 71.8%. Conclusion: The prevalence of pulmonary tuberculosis among National medical college teaching hospital was found to be higher than the Nation pulmonary tuberculosis detection rate, most commonly infecting males. DOI: http://dx.doi.org/10.3126/jmcjms.v1i1.7886 Janaki Medical College Journal of Medical Sciences (2013) Vol. 1 (1):48-52


Med Phoenix ◽  
2020 ◽  
Vol 5 (1) ◽  
pp. 64-70
Author(s):  
Anup Shamsher Budhathoki ◽  
Suprita Gupta ◽  
Sanjay Kumar Sah ◽  
Navin Kumar Sah ◽  
Navin Kumar Sah ◽  
...  

Background: Thyroid dysfunction is one of the most common endocrinopathies after Diabetes Mellitus. Thyroid dysfunction is defined as the alteration in Thyroid Stimulating Hormone (TSH) with normal or abnormal thyroid hormones. Nepalese population have a high risk for thyroid dysfunction with a high prevalence of iodine deficiency. Objective: To study the prevalence of thyroid dysfunction among the patients visiting National Medical College, Birgunj, Nepal for checkup and suggested to assess thyroid function. Materials and Methods: The hospital-based study was conducted in Central Laboratory, National Medical College and Teaching Hospital (NMCTH), Birgunj in collaboration with the Department of Biochemistry. Total 7040 patients visiting Central Laboratory for thyroid function assessment were included in the study between July 2017 to December 2019. The venous blood sample was collected and serum-free triiodothyronine(fT3), free tetraiodothyronine(fT4) and thyroid stimulating hormone (TSH) was estimated by Chemiluminescence Immunoassay (CLIA) method using Access 2 Beckman Coulter analyser. (Beckman Coulter Inc., California, USA). Results: Among 7040 subjects under study, 2138(30%) were found to have thyroid dysfunction with 13% having subclinical hypothyroidism, about 8% of overt hypothyroidism, about 4% with subclinical hyperthyroidism and 5% with overt hyperthyroidism. Majority of the thyroid dysfunction study group belonged to the 16-30 years age group followed by 31-45 years. Mean±SE for TSH, fT4 and fT3 levels show statistically significant differences in different thyroid disorders. Conclusion: The study revealed a high prevalence of subclinical hypothyroidism followed by overt hypothyroidism among the patients visiting National Medical College and Teaching Hospital, Birgunj, Nepal. A higher percentage of females were found to have thyroid dysfunction compared to male.


2020 ◽  
Vol 16 (2) ◽  
pp. 73
Author(s):  
Nurhafizah Rafiani ◽  
Renny Aditya ◽  
Noor Muthmainah

Abstract: A cesarean delivery increases the risk of wound infection it should be prevented by using antibiotics. This study was to determine the pattern of bacterial sensitivity in surgical wounds of cesarean section patients for selected antibiotics, i.e ceftriaxone, cefixime, sulbactam ampicillin, ciprofloxacin, clindamycin and gentamicin.This observational study was conducted at the Ulin Public Hospital in Banjarmasin from July to September 2019. Using a cross sectional approach Samples of bacteria were identidied from 36 that were pusposively sampled, i.e., Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli. Antibiotic sensitivity test showed that Staphylococcus aureus was sensitive against gentamicin (100%),whereas Staphylococcus epidermidis and Escherichia coli. Were intermediately sensitive towards gentamicin (62.5%) and ceftriaxone (80%) Keywords: Antibiotic susceptibility, caesarean section, surgical wound


2017 ◽  
Vol 2 (1) ◽  
pp. 134-137 ◽  
Author(s):  
Binita Pradhan ◽  
SB Pradhan

IntroductionIn developing countries, urinary tract infections (UTIs) are one of the most commonly diagnosed diseases among the patient seeking medical service and being treated with empirical antibiotics which causes resistance.ObjectiveTo find out the prevalence of urinary tract infection and sensitivity pattern of antibiotics among bacterial pathogens isolated in patients attending Kathmandu Medical College Teaching Hospital, Duwakot.MethodologyAll the patients with the clinical suspicion of UTI were sent for urine culture. Prevalence of UTI and urinary pathogens isolated with antimicrobial profile was correlated.ResultA total number of 1735 clinically suspected as UTI cases were sent for urine culture sensitivity. Total culture positive were 239 (13.8%). The majority of isolates were from female patients comprising 180 (75%). The most common pathogenic microorganism isolated was E.coli (79.1%). Second most common organism was Klebsiella (11.7%) followed by Citrobacter (3.34%) and Proteus (2.92%). The isolated microorganism showed maximum number of sensitivity with the antibiotics Ofloxacin and Ciprofloxacin. The isolated microorganism demonstrated resistance with Nalidixic Acid and Co-Trimoxazole. ConclusionUrinary tract infection is a commonly encountered case in general practice. Females are commonly affected than men. The microbiological profile and the antibiotic sensitivity pattern while initiating empirical treatment must be taken into account while planning for the management. Regular supervision of the sensitivity pattern of pathogenic microorganism is mandatory for effective treatment.Birat Journal of Health Sciences Vol.2/No.1/Issue 2/ Jan - April 2017, Page: 134-137


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