scholarly journals Pattern of antibiotic sensitivity of bacteria causing urinary tract infection in a private medical college hospital in Dhaka

2015 ◽  
Vol 14 (1) ◽  
pp. 70-74
Author(s):  
Shahin Sultana ◽  
Marium Khatun ◽  
Md Khoybar Ali ◽  
Nurunnahar Mawla ◽  
Nayareen Akhter

Background: Urinary tract infections (UTI), being the most common infections diagnosed in community and hospital, are to be treated scrupulously considering the type of infecting organism and its antibiotic sensitivity and resistance pattern. Aims and objectives: The aim of the present study was to observe the antibiotic sensitivity pattern of isolated uropathogens from urine samples of patients attending at Shahabuddin Medical College & Hospital, Dhaka, during the period of July 2008 to June 2009. Result: A total of 555 urine samples were studied; of which 84 (15.13%) were culture positive. Among 84 culture positive cases, 84 isolates were identified. Among the isolates, E.coli was the most predominant 61 (62.88%) followed by Enterococci 11 (11.34%), proteus 4 (4.13%) and Pseudomonas 3 (3.09%). Whereas Staphylococcus saprophyticus and Klebsiella showed frequency rate of 2 (2.06%) for each. However Gram positive cocci showed lowest frequency rate of 1 (1.03%). All of the isolates were sensitive to Netilmicin. The majority of isolates were sensitive to Imipenam (92.3%) followed by Amikacin (91.1%), Meropenam (83.3 %), Tetracycline (70%). Sensitivity & resistance rate were same (50%) in Vancomycin & Cefodoxime. Where complete (100%) resistance was shown to Ampicillin, Azithromycin and Cefoxitin. However all isolates were poorly sensitive to cotrimoxazole (35.7%), ciprofloxacin (43%) and nitrofurantoin (44.8%). Conclusion: So, routine urine culture and susceptibility before therapy should be encouraged and periodic evaluation of predominant organisms and their antimicrobial susceptibility pattern should be studied for appropriate selection of antibiotic for effective management of UTI cases.DOI: http://dx.doi.org/10.3329/bjms.v14i1.21562 Bangladesh Journal of Medical Science Vol.14(1) 2015 p.70-74

2013 ◽  
Vol 5 (2) ◽  
pp. 23-26
Author(s):  
Sanya Tahmina Jhora ◽  
Shikha Paul ◽  
Bilkis Ara Begum ◽  
Abul Quashem Chowdhury

Urinary tract infections (UTIs) are one of the most common infectious diseases & an important cause of morbidity in general population. More than 90% of all uncomplicated UTI s are caused by Esch. coli infection. The study was carried out in Department of Microbiology of Sir Salimullah Medical College & Mitford Hospital (SSMC& MH) Dhaka from October 2002 to September 2003. A total of 749 urine samples were studied of which 414 (55.27) showed significant growth. Among the 414 isolates, E sch. coli was the most predominant (82.61%) organism. Esch. coli was highly sensitive to Imipenem (95.02%) followed by Ceftriaxone (86.84%), Cefuroxime (67.54%), Gentamicin (66.08%), and Ceftazidime (55.84%) respectively. Low sensitivity patterns were shown against Nitrofurantoin (44.73%) & Ciprofloxacin (40.64%). The sensitivity to other antibiotics varied from 23.39% to as low as 2.63%. The aim of the present study was to observe the antibiotic sensitivity pattern of isolated Esch. coli from urine samples of patients admitted in inpatient department or visited the out patient department of Sir Salimullah Medical College & Mitford Hospital (SSMC& MH) Dhaka.DOI: http://dx.doi.org/10.3329/bjmm.v5i2.16934 Bangladesh J Med Microbiol 2011; 05 (02): 23-26


Author(s):  
Samirah . ◽  
Darwati . ◽  
Windarwati . ◽  
Hardjoeno .

The bacterial and sensitivity pattern towards antimicrobials on urinary tract infections (UTI) patients are very important to beknown by clinicians to get a successful treatment. The bacterial and sensitivity pattern towards antimicrobials will be changed in differentplace and time, so that those should be analyzed routinely. To evaluate the bacterial and antimicrobials resistance pattern on urinarytract infections patients. A retrospective study on 220 urinary samples in January until December 2004 at Clinical Microbiology subunit of Dr.Wahidin Sudirohusodo hospital . Of 99 samples of UTI, Prevalence of UTI in woman (54.5%) were higher than man (45.5%).Most of sample (28 samples) were found in 0 to 15 years group. The most bacteries in urine were Escherichia coli (39.4%) and Klebsiella(26.3%). Amikacin was sensitive to all bacteries, while amoxicilin and ampicilin were resistance. Prevalence of UTI in women werehigher than in men. Incidens of UTI was highest in children group. The most bacteries in urine samples were Escherichia coli. Amikacinwas sensitive to all bacteries, while Amoxicilin and Ampicilin were resistance.


2012 ◽  
Vol 17 (1) ◽  
pp. 18-21 ◽  
Author(s):  
Belal Ahmed ◽  
Prof Wanaiza ◽  
Mursheda Akhter ◽  
Munir Hasan ◽  
Md Khorshed Alam

Urinary tract infections (UTIs) are some of the most common infections experienced by human. It is also the most common cause of nosocomial infections in adults. The aim of this study was to determine the bacteriological pattern and their sensitivity to commonly used antimicrobial drugs in urinary tract infection in Bangladesh. This was a prospective study conducted in Microbiology department of Dhaka National Medical College, a tertiary level teaching hospital in Dhaka, Bangladesh. A total of 216 culture positive urine samples were examined. Female patient were found to be more 65.7% than male 34.3%. Maximum patients were from 20-35 yrs. age group. The most common isolate was E.coli 84.3%. These E.coli is more sensitive to Imipenem 93.98%, Amikacin 90.52%, Nitrofurantoin 78.88% Ceftazidim 78.26%, Ciprofloxacin 70.67%, Cefuroxime 65.49%,Ofloxacin 60.83%, Ceftriaxone 59.03% and Cephradin 56.96%. Resistance is more in case of amoxicillin 82.41%, Doxycycline 72.42%, Cefixime 58.70% and Nalidixic Acid 57.02%. DOI: http://dx.doi.org/10.3329/jdnmch.v17i1.12186 J. Dhaka National Med. Coll. Hos. 2011; 17 (01): 18-21


2015 ◽  
Vol 1 (4) ◽  
pp. 24-28 ◽  
Author(s):  
Dhruba Acharya ◽  
B Bogati ◽  
GT Shrestha ◽  
P Gyawali

The incidence of urinary tract infections (UTIs) is common in both diabetic and non diabetic patients. Since the microorganisms causing UTI vary in their susceptibility to antimicrobials from place to place and time to time, hence constant screening of trends and susceptibility pattern of predominant   organisms against antimicrobials is essential. The study aims to determine the spectrum of  ropathogens and antibiotic sensitivity pattern in both diabetic and non diabetic patients with clinically suspected UTI .A prospective cross sectional study was conducted during period of February 2013 to July 2013 among 90 diabetic and 90 non diabetic patients attending Dhulikhel Hospital-Kathmandu University Hospital,  Dhulikhel, Kavre (DH-KUH). All samples and isolates were investigated by standard laboratory rocedures. A total of 55 (30.5%) samples showed significant growth. No significant difference among culture positivity rate was noted between diabetic and non diabetic patients (34.5% Vs 26.7%). Escherichia coli was the most frequent organism (64.5% in diabetic and 66.7% non diabetic) followed by Klebsiella sps (22.6% in diabetic and 12.5% in non diabetic). Gentamycin and nitrofurantoin were highly sensitive to E. coli isolated in diabetic patients among the tested antimicrobials followed by  otrimoxazole, norfloxacin and ciprofloxacin. Least sensitivity rate was observed with ampicillin and cephalexin. However, no difference was noted on the sensitivity pattern of the antimicrobials among E. coli isolated between diabetic and non diabetic patients. In this study high proportion of gram negative bacilli with predominant uropathogen being E. coli was noted. Irrespective of the status of diabetes, Staphylococcus sps and Pseudomonas sps were not isolated from UTI patients in our study. The isolation of organisms and their resistance pattern was almost similar between diabetic and non diabetic patients.DOI: http://dx.doi.org/10.3126/jmmihs.v1i4.11998Journal of Manmohan Memorial Institute of Health SciencesVol. 1, Issue 4, 2015Page : 24-28


Author(s):  
Sandinti Deepa ◽  
V. Lakshmaiah ◽  
Arvind Natarajan ◽  
Prabhakar K. ◽  
Raveesha A.

Background: Diabetes Mellitus is reported to increase the risk of Urinary Tract Infection (UTI) with higher probability of drug resistant organisms. Understanding the burden, microbiological profile and antibiotic sensitivity pattern is vital for effective prevention and management. To assess the microbiological profile and antibiotic sensitivity pattern of Urinary Tract infections among type 2 diabetes mellitus patients.Methods: The study was A prospective observational study done on 117 type 2 diabetic subjects aged above 18 years presenting with symptoms of UTI in a tertiary care hospital Urine was analyzed for urine routine examination, culture and antibiotic sensitivity using standard testing methods on a midstream urine sample. Descriptive analysis was carried out by mean and standard deviation for quantitative variables, frequency and proportion for categorical variables.Results: The mean age of the study population was 57 years. Females constituted 62.39% of participants. Burning micturition (52.99%) was the most common presenting symptom. The prevalence of culture positive UTI was 51.28%. Among gram-negative bacilli, Escherichia coli (20.51%), Klebsiella (6.85%) dominated the culture reports. Enterococcus (4.27%) and Staphylococcus aureus (2.6%) were the common gram-positive organisms isolated.  Meropenem was the most effective antibiotic against E. coli (87.5%) and Klebsiella (95%) Vancomycin had 100% sensitivity against Enterococci and S. aureus.Conclusions: More than half of diabetic patients presenting with symptoms of UTI had culture positive UTI, predominantly caused by gram negative organisms. There is a need for comparative studies of Diabetes and controls to explore the key differences in the pattern of UTI.


2021 ◽  
Vol 8 (3) ◽  
pp. 196-199
Author(s):  
Archana Rao K ◽  
Vishwajith ◽  
Ritika Sahkare ◽  
Sangeetha S

Catheter-associated urinary tract infections (CAUTI), remains the commonest hospital-acquired infection (HAI). This emphasizes the need to implement and monitor effective infection control programs to reduce the risk of CAUTI. Aim of the present study was to determine the etiology with antibiotic susceptibility and also to calculate CAUTI rate. The Patients admitted in intensive care unit (ICU), Rajarajeshwari Medical College and Hospital who were on urinary catheter insertion for >48 hours from 1 August, 2019 to 30 September, 2019 were included in the study. Under aseptic conditions urine samples were collected from clinically suspected cases of CAUTI, the samples were processed in the department of Microbiology, as per standard protocols. Uropathogens were isolated, identified and subjected to antibiotic sensitivity test. CAUTI rate was calculated and results were noted. Among 460 patients on catheter in ICU, 28(6%) patients developed clinical signs or symptoms of UTI. Of 28 urine samples cultured, 4(14%) yielded growth of single organis [Escherichia coli (3), Klebsiella (1)] and 24(86%) showed no evidence of growth. 2300 catheter days were obtained of 460 patients on indwelling catheter in ICU. Thus CAUTI rate was 1.74 per 1000 catheter days over a 2 month period.CAUTI remained a great burden to patient safety and a challenge to the infection control team. Implementation of proper care bundles and continuous education to health care workers plays a key role in reducing the CAUTI rates, thereby decreasing the morbidity and hospital stay to the patients.


2018 ◽  
Vol 14 (2) ◽  
pp. 34-37
Author(s):  
Binod Mahaseth ◽  
Madhuri Srivastava ◽  
C. R. Das ◽  
Durga Rawat

Introduction: In developing countries, urinary tract infections (UTIs) are one of the most commonly diagnosed diseases among the patient seeking medical service and are treated with empirical antibiotics which does not provides cure and causes resistance.Objective: To find out the incidence of urinary tract infections and antibiotics sensitivity pattern among bacterial pathogens isolated in patients attending Nepalgunj Medical College and Teaching Hospital, Kohalpur.Methodology: All patients (both male and female) were included in the study with the clinical suspicion of UTI . They had their urine culture done. Incidence of UTI and spectrum of pathogens with their sensitivity were recorded.Result: A total number of 1445 patients were clinically suspected for UT. They had their urine cultura and sensitivity done Total number of patients with culture positive was 391(27.05%). The majority of isolates were from female patients comprising of 314(80.3%) patients. The most common pathogenic microorganism isolated was E.coli (73.65%). Second most common organism was Klebsiella (19.9%), it was followed by Acinetobacter (3.5%), Enterobacter (3.06%), Pseudmonas and Proteus (0.76%) each, Staphylococcus (0.05%) salmonella (0.02%). The isolated microorganisms showed maximum sensitivity to Nitrofurantin and Amikacin. The isolated microorganism demonstrated resistance to cefpodoxime and Cefotaxime.Conclusion: Urinary tract infections is a commonly encountered case in general practice Females are more commonly affected than men. The microbial profile and the antibiotic sensitivity pattern must be taken into account while planning for the management. Regular supervision of the sensitivity pattern of pathogenic microorganism is mandatory for effective treatment.JNGMC, Vol. 14 No. 2 December 2016, Page: 34-37


2012 ◽  
Vol 18 (1) ◽  
pp. 4-6
Author(s):  
Md Badrul Islam ◽  
Munir Hasan

Urinary tract infection is the most common infection causing illness in children and adults. This study was aimed to identify the uropathogens and their antibiotic sensitivity pattern. This study was done in Microbiology Department at Dhaka National Medical College & Hospital, Dhaka, during January, 2010 to December, 2010. A total of 1874 samples of urine were collected from suspected cases of urinary tract infections, from Dhaka National Medical College & Hospital. Among them, 290 (15.48%) showed significant bacterial growth. The most common uropathogens isolated were E.coli 229 (78.97%), Staph. saphrophyticus 15 (5.18%), Coliform 12 (4.13%), Klebsiella spp. 10 (3.44%), Enteococous 10 (3.44%), Staph. aureus 05 (1.72%), Streptococcus spp. 05 (1.72%) and Pseudomonas spp. 04 (1.38%). E.coli is the most common urupathogen and showed sensitivity pattern to Imipenem 84.28%, Amikacin 83.41%, Nitrofurantoin 73.80%, Gentamycin 66.88%, Ciprofloxacin 41.48%, Doxycycline 36.30%, Ceftazidime 34.50%, Ceftriaxone 33.62%, Cefexime 31.0%, Cotrimoxazole 32.31%, Nalidixic acid 24.01%, Cephradine 17.47% and Ampicillin 11.35%. DOI: http://dx.doi.org/10.3329/jdnmch.v18i1.12223 J. Dhaka National Med. Coll. Hos. 2012; 18 (01): 4-6


2017 ◽  
Vol 2 (1) ◽  
pp. 134-137 ◽  
Author(s):  
Binita Pradhan ◽  
SB Pradhan

IntroductionIn developing countries, urinary tract infections (UTIs) are one of the most commonly diagnosed diseases among the patient seeking medical service and being treated with empirical antibiotics which causes resistance.ObjectiveTo find out the prevalence of urinary tract infection and sensitivity pattern of antibiotics among bacterial pathogens isolated in patients attending Kathmandu Medical College Teaching Hospital, Duwakot.MethodologyAll the patients with the clinical suspicion of UTI were sent for urine culture. Prevalence of UTI and urinary pathogens isolated with antimicrobial profile was correlated.ResultA total number of 1735 clinically suspected as UTI cases were sent for urine culture sensitivity. Total culture positive were 239 (13.8%). The majority of isolates were from female patients comprising 180 (75%). The most common pathogenic microorganism isolated was E.coli (79.1%). Second most common organism was Klebsiella (11.7%) followed by Citrobacter (3.34%) and Proteus (2.92%). The isolated microorganism showed maximum number of sensitivity with the antibiotics Ofloxacin and Ciprofloxacin. The isolated microorganism demonstrated resistance with Nalidixic Acid and Co-Trimoxazole. ConclusionUrinary tract infection is a commonly encountered case in general practice. Females are commonly affected than men. The microbiological profile and the antibiotic sensitivity pattern while initiating empirical treatment must be taken into account while planning for the management. Regular supervision of the sensitivity pattern of pathogenic microorganism is mandatory for effective treatment.Birat Journal of Health Sciences Vol.2/No.1/Issue 2/ Jan - April 2017, Page: 134-137


Author(s):  
Magnus Grabe ◽  
Björn Wullt

Infections of the urinary tract are among the most frequent infections encountered in the community and hospital environments. They range from harmless self-curing cystitis to severe pyelonephritis with life-threatening sepsis. Urinary tract infections are often recurrent. Host defence is crucial to control the infection but can also be deleterious in terms of scar formation. Early diagnosis, determination of severity, evaluation of possible risk factors, and assumption of possible pathogen are essential aspects to initiate efficient treatment. Urine culture with antibiotic sensitivity testing is the most important tool to confirm a suspected clinical diagnosis and direct treatment. Patients with urological disease are particularly susceptible to urinary tract infections, and healthcare-associated urinary infections are observed in approximately 10% of hospitalized urological patients. In view of the worsening resistance pattern of common urinary pathogens against available antimicrobial agents, it is important to comply with recommended treatment regimens.


Sign in / Sign up

Export Citation Format

Share Document