scholarly journals Clinical characteristics and outcome of vasculitides

2016 ◽  
Vol 3 (2) ◽  
pp. 3-9
Author(s):  
Buddhi Prasad Paudyal ◽  
Anjana Education Rajbhandari
Keyword(s):  
Medical Records ◽  
Clinical Characteristics ◽  
Cross Sectional Study ◽  
Health Sciences ◽  
Small Vessel ◽  
Small Vessel Vasculitis ◽  
Cross Sectional ◽  
The Mean ◽  
Schonlein Purpura ◽  
Overall Mortality

 Introductions: Vasculitides can cause significant morbidity and mortality if not treated on time. There is lack of data locally. This study aims to define the pattern, clinical characteristics, and outcome of vasculitides.Methods: This was a cross sectional study between January 2011 and December 2015 at Patan Hospital, Patan Academy of Health Sciences, Lalitpur, Nepal. The medical records of patients diagnosed with vasculitides in adults rheumatology service of the hospital were reviewed.Results: Ninety six patients were diagnosed with vasculitides during the study period. The mean age was 42.2 years. Sixty nine (71.8%) patient had small vessel, 20 (20.8%) large vessel and five (5.2%) had variable vessel vasculitides. Seventy five patients (78.1%) had primary and 21 (21.8%) secondary vasculitides. Cutaneous leucocytoclasticangitis was seen in 27 (28.1%), Takayasu arteritis in 17 (17.7), Henoch-Schonlein purpura in 11 (11.4%) and Rheumatoid arthritis associated vasculitis in nine patients. Purpura was present in all 96 (100%). The overall mortality was 9 (9.3%).Conclusions: Primary vasculitides were more common than secondary forms. Small vessel vasculitis was the most common. Cutaneous symptoms were predominant features. The mortality was attributed to active disease, sepsis, and complications of the primary disease. Journal of Patan Academy of Health  Sciences. 2016 Dec;3(2):3-9

scholarly journals Mohs micrographic surgery: a study of 83 cases

2012 ◽  
Vol 87 (2) ◽  
pp. 228-234 ◽  
Author(s):  
Flavianne Sobral Cardoso Chagas ◽  
Bruno de Santana Silva
Keyword(s):  
Cell Carcinoma ◽  
Medical Records ◽  
Cross Sectional Study ◽  
Mohs Micrographic Surgery ◽  
Micrographic Surgery ◽  
Cross Sectional ◽  
The Mean ◽  
Nasal Region ◽  
Cure Rates ◽  
Observation Period

BACKGROUND: Mohs micrographic surgery can achieve high cure rates in the treatment of skin cancer and remove a minimum of healthy tissue. OBJECTIVES: To characterize patients undergoing Mohs micrographic surgery and study issues related to the number of surgical stages. METHODS: A descriptive, retrospective, cross-sectional study was conducted in a micrographic surgery reference center for the period of 2004 to 2010. Data was collected from medical records of 79 patients (83 surgeries). RESULTS: We studied 43 women and 36 men. The mean age was 57.5 ± 14,6 years. Skin types II and III were the most frequent, accounting for 41% and 36.1%, respectively. The most frequent tumor was the basal cell carcinoma (89.1%), and the solid subtype was the most common (44.6%), followed by sclerodermiform histological subtype (32%).The most frequent location was the nasal region (44.6%). The large majority of the operated tumors were recurrent lesions (72.7%). Half of the tumors measured 2 cm or more. In 68.7% of the cases two or more surgical stages were necessary for the removal of the tumors. The observation period was 2 or more years in 75% of the tumors. There was 01 post-Mohs recurrence and 02 patients had metastases during the observation period (both with squamous cell carcinoma). CONCLUSION: The findings coincide with those of the literature, recurrent tumors and tumors larger than 2cm needed more surgical stages for their removal, although there was no statistic difference (p=0,12 and 0,44 respectively).

scholarly journals Association between endometriosis, headache, and migraine

2019 ◽  
Vol 11 (1) ◽  
pp. 19-24 ◽  
Author(s):  
Burcin Karamustafaoglu Balci ◽  
Zehra Kabakci ◽  
Damla Y Guzey ◽  
Bartu Avci ◽  
Murathan Guler ◽  
...  
Keyword(s):  
Nervous System ◽  
Autonomic Nervous System ◽  
Medical Records ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Autonomic Nervous ◽  
Screening Questions ◽  
The Mean ◽  
Id Migraine

Introduction: Available data suggest that there is an association between endometriosis and a group of disorders including autonomic nervous system irregularities. A deeper understanding of relationship between endometriosis and autonomic nervous system is needed as it may lead to novel discoveries on the causes or consequences of endometriosis. In this study, we analyzed the prevalence of migraine in patients with endometriosis. Methods: In this cross-sectional study, medical records of women were reviewed through January 2013 to December 2017. Women with laparoscopically proven endometriosis (n = 185) were compared with those without endometriosis (n = 168). The 3-item screening questions (ID Migraine™) test was used to screen migraine. Data were analyzed using SPSS v25 (IBM Corporation). The χ2 test was used for analyzing the nominal parameters and group comparisons. Pearson χ2 was used to study the association between endometriosis and migraine. Results: The mean age was 31.86 ± 4.49 years of the endometriosis group and 28.95 ± 5.11 years of the controls (p = 0.408). The two pre-screening questions of ID Migraine test were answered positively by 86 patients of the endometriosis group (75.4%) and by 53 patients of the control group (54.6%) (p = 0.001). Of these patients, 51 (44.7% of endometriosis group) and 26 (26.8% of control group) were diagnosed as having migraine using 3-item Migraine questionnaire (p = 0.007). Conclusion: This study showed that the prevalence of migraine was significantly higher in patients with endometriosis. Because there is a strong correlation, patients with endometriosis should be screened for headache and migraine to increase the benefits of care.

scholarly journals Evaluation of Demographic, Clinical and Beyond Clinical Characteristics in Patients with Multiple Sclerosis in Rafsanjan City, Iran

2017 ◽  
Vol 2 (2) ◽  
pp. 63
Author(s):  
Amir Moghaddamahmadi ◽  
Pouria Yazdian-Anari ◽  
Siamak Kazemisufi ◽  
Alireza Vakilian ◽  
Aliasghar Ranjbartotoei ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Clinical Characteristics ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Mcdonald Criteria ◽  
Male Female Ratio ◽  
The Central Nervous System ◽  
The Mean

Background and objectives: Multiple sclerosis is a chronic and progressive autoimmune disease of the central nervous system that causes motor and sensory impairment and physical disability in patients. This study was conducted to determine the demographic, clinical, and beyond clinical characteristics in patients with multiple sclerosis to help identify common disabilities and better understand of the specific needs of these ones.Materials and methods: This descriptive cross-sectional study was carried out on 50 MS patients in Rafsanjan, Iran. A definitive diagnosis has been done according to neurologist and McDonald criteria. The neurologist conducted examinations. The demographic data were recorded using questionnaire. MRI images were analyzed with the help of radiologist and all data were analyzed using SPSS software.Results: The mean age was 33.81±8.38 years and male/female ratio was 7/42. According to data, 66.7% of the patients were suffering from relapsing-remitting type (RR) disease, and most lesions on MRI in these patients were observed in pyramidal and JuxtaCortical areas. The mean EDSS scores of patients was 1.46. The duration of disease and the number of attacks had a significant correlation with educational level (P<0.05); age was significantly associated with pyramidal, mental and sphincter symptoms (P<0.05).Conclusion: These results suggest that the prevalence of MS in women is higher than in men, especially among housekeeper women. Relapsing and remitting disease showed higher frequency.

Psychometric properties of Body Mass Index in screening malnutrition of COPD inpatients admitted at Nguyen Tri Phuong Hospital, Vietnam: a cross-sectional study

MedPharmRes ◽  
2021 ◽  
Vol 5 (3) ◽  
pp. 27-33
Author(s):  
Uyen Phuong Truong ◽  
Lan-Anh Thi Pham ◽  
Ngoc Van Anh Huynh ◽  
Thi Van Tran ◽  
Gia Kien To
Keyword(s):  
Body Mass Index ◽  
Health Status ◽  
Nutritional Status ◽  
Body Mass ◽  
Medical Records ◽  
Handgrip Strength ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Mean

Introduction: This study assessed the validation of Body Mass Index (BMI) against Subjective Global Assessment (SGA), and identify the prevalence of malnutrition and its associated factors in Chronic Obstructive Pulmonary Disease (COPD) inpatients at Nguyen Tri Phuong Hospital, Ho Chi Minh City, Vietnam. Methods: A cross-sectional study was conducted to consecutively select COPD inpatients based on medical records and consultancy with doctors. A structured questionnaire was designed to collect socio-demographic characteristics, health status and comorbidities, nutritional status, and handgrip strength. Nutritional status was assessed using SGA and BMI. Handgrip strength was measured using a hand dynamometer. Health status was collected from medical records. Results: The mean age of 83 COPD inpatients recruited in this study was 67 (SD=10.4) years. Most of the sample population was ≥60 years old (75%), male (86%), Kinh ethnic (89%), married (72%), not currently working (70%), and less than junior high school (81%). Nearly 68% had at least one comorbidity and 27% were active smokers. The mean handgrip strength was 21.6 kg (SD=8.7), and mean weight was 53.9 kg (SD=10.0). The mean BMI was 20.4 kg/m2 (SD=3.4) with 58% having BMI <21 kg/m2. SGA provided the prevalence of malnutrition of 65%. Age-group, BMI and handgrip strength were associated with malnutrition. A BMI cut-off point of <21 kg/m2 provided the highest ROC area of 84% (95%CI: 76%-92%). Conclusion: Malnutrition is common in COPD inpatients. This study confirms findings of previous studies that a BMI cut-off point of <21 kg/m2 was sensitive and specific for screening malnutritional risk at bedside.

Association between vitamin D level and prognostic factors among patients infected with SARS-CoV-2

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Mehrdad Haghighi ◽  
Seyed Shayan Ebadi ◽  
Hussein Soleimantabar ◽  
Atefe Shadkam ◽  
Seyed Alireza Ebadi ◽  
...  
Keyword(s):  
Vitamin D ◽  
Prognostic Factors ◽  
Medical Records ◽  
Lymphocyte Count ◽  
Cross Sectional Study ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Reactive Protein ◽  
The Mean ◽  
D Dimer

Abstract Objectives The present study aimed to evaluate the presence of any relationship between vitamin D and prognostic factors among patients infected with SARS-CoV-2. Methods This retrospective cross-sectional study was conducted among patients admitted from March to August 2020 in a referral hospital, Tehran, Iran. All patients aged 18–65 who had not any comorbidity participated in the study. The diagnosis of COVID-19 was established using the rRT-PCR test for SARS-CoV-2 detection. Then the incidence of lung involvement and biochemical markers including vitamin D level, c-reactive protein, D-dimer, lymphocyte count, platelet count, white blood cell count, and lactic acid dehydrogenase, were extracted through medical records. Results Altogether, 84 patients met our study criteria, and the information of 68 (80.9%) participants were collected. Among all 68 patients, 45 (66.2%) were male. The mean (SD) age of all participants was 52.4 (10.4) years old. Among 24 (35.2%) clients who died due to SARS-CoV-2, 20 (83.3%) patients were male (p=0.02). The mean (SD) of vitamin D level was 24.1 (13.6) ng/dL. No association between vitamin D level and prognostic factors, including CRP, lymphocyte count, D-dimer, LDH, and HRCT scan score, was observed. Also, the vitamin D level of the dead patients was not significantly different from that of the treated patients. Conclusions Our findings indicated no significant relationship between vitamin D level and prognostic factors or outcomes of patients infected with SARS-CoV-2.

scholarly journals Comparison of Juvenile and Adult Onset Refractory Spondyloarthritis Patients Attending a Tertiary Rheumatology Clinic

2020 ◽  
Vol 38 (2) ◽  
pp. 79-85
Author(s):  
Md Nazrul Islam ◽  
Khaleda Islam
Keyword(s):  
Disease Activity ◽  
Clinical Characteristics ◽  
Disease Duration ◽  
Age At Onset ◽  
Real Life ◽  
Cross Sectional Study ◽  
Adult Onset ◽  
Cross Sectional ◽  
Asas Classification Criteria ◽  
The Mean

Objectives: To compare the demographic and clinical characteristics of juvenile onset refractory spondyloarthritis (JOSpA) with a group of adult-onset refractory spondyloarthritis (AOSpA) patients. Methods: In this real-life, cross-sectional study, a total of 215 SpA patients (refractory to two NSAIDs and/or DMARDs) were enrolled following ASAS classification criteria from a rheumatology center in Dhaka, Bangladesh. Based on age, the patients were divided into JOSpA group and AOSpA group for analysis. The patients’ demographics, quality of life, laboratory and clinical characteristics were compared and analyzed between the two groups using chisquare and independent sample t-test. Results: Among 215 patients, 57 (53 males, 4 females) were in JOSpA group, and 158 (126 males, 32 females) were in AOSpA group. Most patients were male in both groups (P=0.02). The mean age at diagnosis for JOSpA and AOSpA were 27.68±9.5 and 40.28±10 years respectively (P=0.00), and mean age at onset of disease in JOSpA and AOSpA were 12.33±3.62 and 29.58±96.5 years respectively. The mean disease duration was 15.36±9.3 months in JOSpA compared to 10.70±7.1 months in AOSpA group (P=0.00). Sixteen (28.1%) JOSpA and 9 (5.7%) AOSpA patients were undernourished, (P=0.00). On the contrary, obesity was more prevalent in AOSpA patients (41.1%) than those in JOSpA patients (21.1%) (P=0.00). There were significant differences in mean haemoglobin (11.38±1.7 and 10.94±1.3 g/dl) (P=0.05) and mean serum creatinine (0.94±0.2 and 0.86±0.2 mg/dl) (P=0.03) levels in AOSpA and JOSpA groups respectively. HLA-B27 was done in 20 JOSpA and 61 AOSpA patients. Among them, 19 (95%) were positive in JOSpA and 55 (90.16%) were positive in AOSpA groups. Similarly, hips involvement was higher in JOSpA group 19 (33.3%) compared to the AOSpA group 21 (13.3%) (P=0.004). Significant differences were observed in mean disease activity parameters, patient global assessment (PGA) (7.86±1.2 vs 7.38±1.4, P=0.02), ASDAS-CRP (4.60±0.8 vs 4.33±0.9, P=0.05), and ASDAS-ESR (4.49±0.8 vs 4.17±1.0, P=0.02) in JOSpA and AOSpA groups respectively. The modified Stoke AS Spinal Score (mSASSS) in AOSpA group was higher (24.18±17.22) than that of JOSpA group (17.10±9.6) (P=0.00). Conclusions: In JOSpA patients, under nutrition, hip involvement, longer disease duration, uveitis, PGA, low Hb level and ASDAS-ESR disease activity scores were higher. On the contrary in AOSpA group, male gender, married subjects, obesity, higher creatinine level and mSASSS scores were higher. J Bangladesh Coll Phys Surg 2020; 38(2): 79-85

Epidemiological Study of Henoch-Schonlein Purpura and its Characteristics in Infected Children During 2009-2016

2021 ◽  
Vol 15 (6) ◽  
pp. 1629-1633
Author(s):  
Sadegh Dehghanmehr ◽  
Reza Naghdi ◽  
Farahnaz Irandegani ◽  
Hamed Taheri ◽  
Omar Pourbalouch ◽  
...  
Keyword(s):  
Clinical Manifestations ◽  
Cross Sectional Study ◽  
Additional Treatment ◽  
Henoch Schonlein Purpura ◽  
Cross Sectional ◽  
Cutaneous Manifestations ◽  
The Mean ◽  
Autumn And Winter ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura

Introduction: Due to the different complications caused by Henoch-Schonlein purpura and in order to prevent additional treatment costs for patients, we decided to investigate the clinical features of cases of Henoch-Schonlein purpura. Materials and Methods: In this descriptive cross-sectional study, 52 children in whom the diagnosis of Henoch-Schonlein purpura was confirmed were enrolled in the study from 2009 to 2016. The instruments of this research include a researcher-made questionnaire with two parts. The first part is related to demographic characteristics including age, sex and season of referral and the second part was related to morbidity such as various symptoms. Data were collected from patients’ records and interviews with families and were analyzed using SPSS V.22. Results: Out of 52 patients, 30 (57.7%) were boys and 22 (43.3%) were girls. The mean age of patients was 3.02 to 6.58 years. Autumn and winter had the most clients of Henoch-Schonlein purpura. One of the most common manifestations seen in most patients was cutaneous manifestations. There was no significant relationship between gender and clinical manifestations and seasons of the year with these manifestations (p> 0.05). The results showed that age was significantly associated with renal manifestations (P <0.05). Conclusion: The results of this study showed that the prevalence of Henoch-Schonlein purpura disease is higher in boys. Cutaneous manifestations were seen in most patients and in patients with renal manifestations, the mean age was higher and significant. Keywords: Henoch-Schonlein purpura, clinical manifestations, complications, gender, age

scholarly journals BREAST CANCER IN WOMEN: RECURRENCE AND SURVIVAL AT FIVE YEARS

2015 ◽  
Vol 24 (3) ◽  
pp. 740-747
Author(s):  
Valéria Costa Peres ◽  
Danyelle Lorrane Carneiro Veloso ◽  
Raphaela Maioni Xavier ◽  
Ana Karina Marques Salge ◽  
Janaína Valadares Guimarães
Keyword(s):  
Breast Cancer ◽  
Medical Records ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Exact Test ◽  
Kaplan Meier ◽  
Reference Hospital ◽  
Advanced Stages ◽  
Local Regional Recurrence ◽  
Overall Mortality

ABSTRACTWomen undergoing breast cancer treatment are still at risk of recurrence. This study investigated the association among survival and relapse with staging of breast cancer in women treated in an oncology reference hospital in Goiânia-GO, Brazil over a five-year period after diagnosis in 2008. This descriptive, retrospective, cross-sectional study was conducted with the medical records of 460 women. Data were analyzed using Fisher's Exact Test and the Kaplan Meier Curve. Overall, mortality, local/regional recurrence and metastasis were at 14.1%, 6.5% and 25.2%, respectively. There was an improvement in the survival of women with breast cancer at five years, but there is still a significant number of women diagnosed in advanced stages and experiencing recurrence, indicating there is a need to improve detection of the disease in its early stages and recurrences.

scholarly journals Clinical and Para-clinical Features of Brucellosis With and Without Spondylodiscitis

2021 ◽  
Vol 8 (2) ◽  
pp. 39-44
Author(s):  
Fariba Keramat ◽  
Seyyed Hamid Hashemi ◽  
Farzaneh Esna-ashari ◽  
Kaveh Kaseb
Keyword(s):  
Back Pain ◽  
Medical Records ◽  
Clinical Manifestations ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
Vertebral Involvement ◽  
Spinal Mri ◽  
The Mean

Background: Brucellosis is a common zoonotic disease with protean clinical manifestations. Osteoarticular involvement is the most common complication of the disease. This study aimed to compare the clinical and para-clinical manifestations of brucellosis among the patients with and without spondylodiscitis. Methods: In this comparative and cross-sectional study, 135 patients having brucellosis with and without spondylodiscitis and admitted to Sina hospital in Hamadan, Iran from March 2009 to March 2014 were included. Clinical and para-clinical data of the patients were obtained from their medical records in the hospital based on a designed checklist. Results: Thirty-five patients having brucellar spondylodiscitis (BS) with the mean age of 55.60±14.31 years, and 100 patients having brucellosis without BS with the mean age of 43.27±18.35 years were examined. A significant difference was found between the mean age of the patients with spondylodiscitis and that of those without spondylodiscitis (P<0.001). All patients with spondylodiscitis complained of back pain and vertebral tenderness, while 60% of the patients without BS suffered from back pain but experienced no vertebral tenderness (P=0.003). The most common vertebral involvement in spinal MRI of the patients with BS was L4-L5 (45.7%). Patients with spondylodiscitis had more increased ESR and CRP than those without spondylodiscitis (P<0.001). Conclusion: It is recommended that Brucellar spondylodiscitis be considered in the differential diagnosis of the patients with prolonged fever, back pain, and vertebrae tenderness in the endemic areas.

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