scholarly journals Ocular manifestations in patients with corona virus disease (COVID-19)

2021 ◽  
Vol 8 (2) ◽  
pp. 32-37
Author(s):  
Ranjana Sharma ◽  
Bishnu Prasad Sharma ◽  
Keshav Raj Sigdel ◽  
Sudeep Adhikari ◽  
Sudesh Subedi ◽  
...  

Introduction: Corona virus disease (COVID-19) has affected many subspecialties including ophthalmology. We aimed to determine the ocular manifestations of COVID-19 patients treated in a dedicated tertiary care hospital, in Nepal. Method: This was a descriptive cross-sectional study in hospitalized COVID-19 patients in Patan Hospital, Patan Academy of Health Sciences, Kathmandu, Nepal. Data were collected during 6 months from November 2020 to May 2021 to achieve a for a specified sample size of 90. Ophthalmological manifestations were recorded in the consenting participants. Ethical approval was obtained. Result: One or more ocular manifestations were seen in 3.4% of admitted COVID-19 patients. Bilateral diffuse red eyes was the most common manifestation. Conclusion: Bilateral diffuse red eye was the common ocular manifestation in admitted COVID-19 patients.

2019 ◽  
Vol 57 (219) ◽  
Author(s):  
Ananta Uprety ◽  
Binod Pantha ◽  
Lochan Karki ◽  
Suresh Prasad Nepal ◽  
Milan Khadka

Introduction: Organophosphorous poisoning is a common problem prevalent in Nepal. Intermediate syndrome is a common clinical feature seen among the patients those have ingested poison. There is a scarcity of data related to intermediate syndrome and other general complications in patients with organophosphorous poisoning in context of Nepal. This study was carried out to observe the prevalence of intermediate syndrome and the general complications of oraganophosphorus poisoning among admitted patients in a tertiary care hospital. Methods: This was a descriptive cross-sectional study conducted at a tertiary care hospital from April 2008 to June 2009 after ethical approval was from Institiutional Review Board of tertiary care hospital. Forty four patients with history of ingestion of organophosphorus poisoning within 24 hours were included in our study through convenience sampling. Clinical examinations were done to look for Intermediate syndrome. Data was entered in Statistical Package for Social Sciences and point estimate at 95% of CI was calculated along with frequency and proportion for binary data. Results: Out of 44 patients, features of intermediate syndrome were seen in 40 (90.9%) at 95% of CI (84.2-97.6) patients in the study. The frequency of intermediate syndrome signs like weakness of neck flexion, inability to sit up and swallowing difficulty were seen among the patients. Complications like pneumonia 4 (9.09%), hyponatremia 3 (6.8%), hypokalemia 1 (2.27%) and bradycardia 1 (2.27%) were seen in the study. Mortality seen in the study was 2 (4.5%) among the admitted patients. Conclusions: Prevalence of intermediate syndrome was higher compared to other studies done in similar settings. Complications like pneumonia, hyponatremia, hypokalemia and bradycardia were seen among the patients.


Author(s):  
Shivani Juneja ◽  
Proteesh Rana ◽  
Parvinder Chawala ◽  
Rekha Katoch ◽  
Kulvir Singh ◽  
...  

Abstract Objectives The use of Hydroxychloroquine (HCQ) prophylaxis has been recommended by the National task force constituted by the Indian Council of Medical Research (ICMR) for the prevention of corona virus disease 2019 (COVID-19) among healthcare workers (HCWs). However, this recommendation was based essentially on the preclinical data and limited clinical experience. The aim of this study was to evaluate the efficacy and safety of HCQ as a pre-exposure prophylaxis for COVID-19 infection among Indian HCWs. Methods A cross-sectional study was conducted among HCWs of a tertiary care hospital in north India. The HCQ prophylaxis was initiated among 996 HCWs and they were followed up to 8 weeks for conversion to COVID-19 positive status and any adverse drug reaction (ADR). Results About 10.3% of the study participants were tested positive for COVID-19 which was comparable to the positivity rate among HCWs not taking HCQ prophylaxis (9.7%). Conclusions HCQ was well tolerated at a weekly dose of 400 mg for 8 weeks but provided no additional benefit in prevention of COVID-19 among HCWs.


Author(s):  
Amruta V. Dashputra ◽  
Rupesh T. Badwaik ◽  
Archana S. Borker ◽  
Amit P. Date ◽  
Priyanka Survase

Background: Vitamin-D is critically important for development, growth and maintenance of health of human being. Many evidences show association between vit-D deficiency and several serious health conditions. Data collection on use of drugs is being obtained with the aim of optimizing drug therapy. So far till date only few studies about prescription pattern of vit-D have been found. Hence it is very important to do audit of prescriptions of vit-D. The aim of the study is to provide concise and updated information about the use of vit-D in tertiary care hospital and to record demographic details of patients.Methods: After ethical approval, this cross sectional study was conducted at tertiary health centre. Patient and drug data (name of drug, dose, dosage form and route of administration) was collected from the patient’s prescriptions in OPD.Results: Highest prescriptions of vit-D were found in orthopedic department (22% of total prescriptions of that department). Prescribing percentage of vit-D in medicine department was 4.6%, dermatology 1.5% and in psychiatry 0.8% of total prescriptions. Prescriptions of vit-D in combination with calcium were found in orthopedics (52%), medicine (7%) and obstetrics and gynecology (10%) departments.Conclusions: Highest prescriptions of vit-D alone and with calcium found in orthopedic department. Periodic therapeutic audit is necessary to rationalise the use of vit D.


2021 ◽  
Vol 19 (1) ◽  
pp. 97-100
Author(s):  
Anjal Bisht ◽  
Samrat Shrestha ◽  
Priya Bajgai ◽  
Milan Khadka ◽  
Parimal Koirala ◽  
...  

Background: There is a close correlation between ankylosing spondylitis and uveitis, other less common ocular manifestations being episcleritis and scleritis. Though the prognosis of uveitis is good, prompt treatment is required to prevent long-term complications. This study aimed to estimate the prevalence of uveitis in patients with ankylosing spondylitis who follow outpatient clinic of a tertiary care hospital.Methods: A descriptive cross-sectional study was done in medicine outpatient department of a tertiary care hospital for 6 months. Ethical clearance was obtained from the institutional review board of National Academy of Medical Sciences. Convenient sampling was done. The data collected were entered in Microsoft excel to tabulate the data and analyze the results.Results: Out of 81 participants, 26 patients had a history of uveitis (32%). Most of the patients in this study were of 18-30 years. Uveitis was most common in patients with (axial to be added) spondylarthritis and peripheral inflammatory arthritis (41%) compared to those with just the axial disease (32%). Uveitis was more common among males (32.2%) than females (31.5%).Conclusion: In patients with spondyloarthritis uveitis was present in 32% of the patient with more common in patient with both axial and peripheral arthritis. Timely diagnosis of uveitis in ankylosing spondylitis can prevent the sequelae with prompt treatment. Keywords: Ankylosing spondylitis; spondyloarthritis; uveitis


2021 ◽  
Vol 8 (2) ◽  
pp. 85-90
Author(s):  
Suraj Rijal ◽  
Sunil Adhikari ◽  
Darlene Rose House

Introduction: Stroke is one of the most common causes of morbidity and mortality in Nepal. It is the 3rd most common cause of death worldwide. In Nepal Non-communicable diseases in Nepal(NCDs) states that stroke accounts for 42% of all deaths and is estimated to reach about 66.3% of all deaths by 2030. Method: A retrospective cross-sectional study of all stroke patients seen in Patan Hospital Emergency Department for a period of 1 y. Demographic data, presenting complaint, time of onset of symptoms, time presenting to the Emergency, patient’s risk factors for stroke, head CT findings (hemorrhagic or ischemic stroke) were analyzed descriptively. Ethical approval was taken. Result: Total 170 patients (96 males i.e.56.5% and 74 females i.e. 43.5%) were analyzed. 130(76.5%) were ischemic CVA and 40 (23.5%) were hemorrhagic CVA. The most common presenting symptoms was hemiparesis and speech changes. Conclusion: Stroke is a common disease seen in Nepal, with higher percentages of hemorrhagic stroke.


2019 ◽  
Vol 57 (217) ◽  
Author(s):  
Sanzida Khatun ◽  
Dipendra Thakur ◽  
Diwakar Kumar Shah

Introduction: Appendicitis is one of the most common causes of acute abdomen. The clinicalpresentation of appendicitis and its susceptibility to acute inflammation may be affected by thelength and position of vermiform appendix. Length and position of appendix are variable. Theaim of the study was to find the prevalence of retrocaecal appendix among patients undergoingappendectomy for appendicitis. Methods: A descriptive cross-sectional study was performed in 264 patients undergoingappendectomy in Department of Surgery, Nobel Medical College, Biratnagar, Nepal 1st May, 2018to 15th May, 2019. Ethical approval was taken. Simple random sampling was done. The position ofappendix was noted before appendectomy. Subgroup analysis was done on the basis of gender andlength of appendix recorded in centimeters with a measuring scale immediately after removal ofappendix. Data was collected in excel and was analyzed in SPSS version 16. Results: Prevalence of retrocaecal appendix among patients with appendicitis was 95 (35.98%).Similarly, other positions noted were pelvic in 67 (25.37%), post-ileal in 61 (23.10%), pre-ileal in 11(4.16%) and subcaecal in 30 (11.36%) individuals. The length of appendix ranged from 1.7 cm to 14.7cm. The mean length was 8.67±2.44 cm. Conclusions: The most common position of appendix in patients with appendicitis is retrocaecalposition followed by pelvic position in both males and females.


2017 ◽  
Vol 5 (2) ◽  
pp. 6-10
Author(s):  
Anira Vaidya ◽  
Nayan Kamal Sainju ◽  
Sunil Kumar Joshi

Background: Musculoskeletal disorders are common work-related health problems affecting professionals in many sectors. Surgeons are among the most vulnerable as they have to work for long hours in unfavorable posture. Objective: Aim of this study was to determine both prevalence of work related musculoskeletal disorders and types of ailments among surgeons of different sub-specialties in a tertiary care hospital in Kathmandu. Methods: In This cross sectional study was conducted in Bir Hospital, a tertiary care hospital in Kathmandu. A total of 50 surgeons of different sub-specialties were surveyed. Self-reported questionnaires included i) socio-demographic information, ii) Dutch Musculoskeletal Questionnaire on ergonomic hazards and iii) Nordic musculoskeletal disorders questionnaire on pain and discomfort. Data were analyzed using SPSS version 20. Result: Respondents were 40 male and 10 female surgeons with mean age of 38.9 years. Forty-four respondents (88%) reported that their job usually require them to stand for long hours, and41 (82%) also reported that they would work in the same posture for long period of time. In addition, 43 (86%) also reported that they would have to bend their trunk slightly during their job. Thirty-five respondents (70%) reported having at least one musculoskeletal disorder. Twenty-three (65.7%) surgeons had to miss their job at least once during last 12 month of which nineteen (54.3%) missed them in last 7 days.Conclusion: This survey showed that various musculoskeletal ailments were common among surgeons of all sub-specialties in our hospital which is likely one of the common and a serious occupational hazards in this population.


2019 ◽  
Vol 57 (220) ◽  
Author(s):  
Kalpana Silwal ◽  
Sarala Joshi

Introduction: Verbal abuse is the act of forcefully criticizing, insulting or denouncing another person.Verbal abuse can be devastating to doctors and may cause long lasting emotional and psychologicaldamage. This study aims to find the prevalence of verbal abuse among doctors in tertiary carehospital. Methods: This descriptive cross-sectional study was conducted among doctors in a tertiary carehospitals, Chitwan from January to July, 2019 after taking ethical approval. Convenience samplingwas done. Self administered questionnaire was distributed and data was collected. Point estimateat 95% CI was done for binary data along with frequency and proportion. Data were entered andcalculations were done in Microsoft excel. Results: Verbal abuse was found among 80 (33.3%) respondents at 95% Confidence Interval (27.51-39.09%) and most 51 (63.8%) of perpetrators were relatives of the patients. Most 38 (47.5%) of thedoctors were often worried in workplace. Incident of the verbal abuse was more 35 (43.6%) inmorning and least 14 (17.4%) in night. Most 22 (27.5%) of the doctors did not take any action forincident although most 42 (52.5 %) of the doctors were encouraged by colleagues to take action. Conclusions: Prevalence of verbral abuse among the doctors were found out to be similar as theprevious studies conducted in similar settings. This study has shown that doctors were frequentlyverbal abused by patient’s relatives and were abused mostly in morning shift and were often worriedin workplace.


2021 ◽  
Vol 71 (4) ◽  
pp. 1436-40
Author(s):  
Madiha Sundus ◽  
Aisha Akhtar ◽  
Asim Aslam ◽  
Nadia Iftikhar ◽  
Muhammad Anjum ◽  
...  

Objective: To provide an insight into the frequency of cutaneous manifestations in patients with Corona Virus Disease of 2019 COVID-19), along with an association of these findings with the severity of the disease. Study Design: Cross-sectional study. Place and Duration of Study: Tertiary care hospital, Rawalpindi Pakistan, from May to Jul 2020. Methodology: We collected data from 412 confirmed cases of COVID-19 patients directly who were >12 years of age. The data included names of patients, their genders, ages, dates of admission, severity category, presence or absence of symptoms and cutaneous findings along with description of cutaneous findings if present. The data was evaluated using Statistical Package for the Social Sciences (SPSS) version 23. Results: Eleven out of the total 412 patients with COVID-19 included in our study were found to have cutaneous findings. The frequency of cutaneous manifestations associated with COVID-19 was calculated to be 11 (2.7%). Increasing age proved to be positively correlated with increasing severity of the disease whereas no association was found between gender and severity of the disease. Conclusion: Infection with COVID-19 may result in dermatological manifestations with various clinical presentations, which may aid in better understanding and management of the disease.


2018 ◽  
Vol 6 (2) ◽  
pp. 15-21
Author(s):  
M Basnet ◽  
N Sapkota ◽  
S Limbu ◽  
DD Baral ◽  
N Rai

 Introduction: Worldwide, the morbidity of psychiatric illnesses is on the rise. Quality in-patient services are a part of quality mental health services provision. Knowledge about the pattern of illness among patients admitted to the ward could help the service providers to plan better and provide better services. This study was undertaken to explore the clinico-demographic profile of patients admitted to psychiatric ward at BPKIHS..Material And Method: This is a hospital based retrospective and cross-sectional study. After ethical approval from the Institutional Review Committee, the data of all patients admitted to Psychiatry Ward from 1st January 2007 to 31st December 2016 were collected from the data-base of Medical Records Section. The diagnoses were made according to the ICD-10 criteria. 3687 admissions were processed for the analysis.Results: Of the 3687 admissions, 2183(59.2%) were male and 1504 (40.8%) were female. The age range was 4-92 years with mean age of 32.4(±12.6) years. The majority of the admissions (62.5%) were from Sunsari (1159,31.4%) and surrounding districts (1147,31.1%). Mood disorders were the commonest diagnoses 1788(48.5%) followed by schizophrenia, schizotypal and delusional disorders 829(22.5%) and psychoactive substance use disorders 813(22.1). 92% of patients admitted were improved on discharge and three cases expired in the ward. Out of 3687 admissions, 957(26%) were readmissions.Conclusion: Mood disorders were the commonest diagnosis among the admitted patients. Outcome of hospital stay was good with 92% discharged in improved condition and only three mortalities in 10 years duration. Address seems to significantly affect the service utilization. J Psychiatrists’ Association of Nepal Vol. 6, No. 2, 2017, Page: 15-21


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