Clinico-Epidemiological Profile of Patients with Psoriasis in a Tertiary Care Hospital of Western Nepal

INTRODUCTION: Psoriasis is a common, chronic, inflammatory and proliferative condition of the skin which poses a significant health problem in general population. It is clinically characterized by erythematous plaques covered by silvery white scales, associated with systemic manifestations in many organ systems. MATERIAL AND METHODS: This is a descriptive study conducted at the Department of Dermatology, Universal College of Medical Sciences, Bhairahawa, Nepal. All psoriasis patients who gave consent were clinically examined and proforma documentation including patient’s clinical and demographic details was studied. RESULTS: Fifty two psoriasis patients were studied. The median age was 40 years and male: female ratio was 1.7:1 with 33 (63.5%) male and 19 (36.5%) female psoriasis patients. The most common clinical type of psoriasis observed according to morphology was chronic plaque psoriasis 45 (86.54%) and according to involvement of anatomical site was nail psoriasis 33 (63.5%). This study showed that 30 (57.7%) had no symptoms of pruritus and pain and 29 (55.8%) of psoriatic cases had seasonal variation. The commonest treatment modality was a combination of oral and topical medication 29 (55.8%). CONCLUSION: Psoriasis is a common skin disorder associated with systemic manifestations seen by dermatologists. This study outlines the clinico-epidemiological profile of patients with psoriasis which can provide further guidance for taking appropriate measures in diagnosing, providing adequate treatment, and undertaking various preventive measures among psoriasis patients.

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Risk factors, clinico-epidemiological profile of tuberculosis among children attending a tertiary care hospital: a two year study

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20181501 ◽

2018 ◽

Vol 5 (3) ◽

pp. 851

Author(s):

Ravikumar Tenali ◽

Naveen Kumar Badri ◽

Jithendra Kandati ◽

Munilakshmi Ponugoti

Keyword(s):

Risk Factors ◽

Clinical Features ◽

Tertiary Care ◽

Epidemiological Surveillance ◽

P Value ◽

Tuberculous Lymphadenitis ◽

Care Hospital ◽

Female Ratio ◽

Extra Pulmonary ◽

Epidemiological Profile

Background: TB remains as the one among the top 10 causes of death worldwide. In 2016, 10.4 million people fell ill with TB, and 1.7 million died from the disease with 0.4 million with HIV. At least 1 million children become ill with TB each year. Children represent about 10-11% of all TB cases. Having knowledge of the risk factors for tuberculosis infection in children is important to evaluate the level of ongoing transmission of infection and to help adapt activities within national TB control programs. The main objective is to study the risk factors and their association and variable clinical features in cases of pulmonary and extra pulmonary tuberculosis.Methods: The main objective is to study the risk factors and their association and variable clinical features in cases of pulmonary and extra pulmonary tuberculosis.Results: 98 cases of TB were confirmed out of total 628 with a prevalence of 17.07% in the study with 78 PTB cases and 20 EPTB. Females were more with male to female ratio of 0.7:1.5-9 years was the most common age group in the study. Statistically significant association was found between old history of ATT, HIV positivity, contact with an open case of TB and malnutrition (p value<0.05). TB meningitis was the most common EPTB (10/20 cases) followed by tuberculous lymphadenitis (5/20). 69.39% (68/98 cases) were smear positive, radiologically 59.18% of cases were positive and Tuberculin skin test was positive in 46.94%.Conclusions: Childhood tuberculosis is a neglected entity in developing countries due to underreporting and difficulties in diagnosis due to variable clinical picture in children. Hence epidemiological surveillance studies in children are required to determine the actual prevalence of pulmonary and extra pulmonary cases of tuberculosis. Increased efforts are required to isolate TB bacilli from body fluids to identify early the childhood cases and manage them to prevent disease burden in the community.

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Study of clinico-epidemiological profile of leprosy patients at tertiary care centre of South Gujarat region

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20201580 ◽

2020 ◽

Vol 6 (3) ◽

pp. 355

Author(s):

Kautuk K. Patel ◽

Anjum M. Momin ◽

Ankita A. Mistry ◽

Jignesh B. Vaishnani

Keyword(s):

Tertiary Care ◽

National Level ◽

Public Health Problem ◽

Warning Signs ◽

Tertiary Care Centre ◽

Female Ratio ◽

Male Female Ratio ◽

Leprosy Patients ◽

Epidemiological Profile ◽

Epidemiological Characteristics

Background: Leprosy is a chronic feared illness causes by Mycobacterium leprae. It was eliminated as a public health problem in India in 2005. But still, India contributes more than 60% of all new cases of leprosy.Methods: A retrospective analysis of 307 patients attending the leprosy clinic of the dermatology out patient department, SMIMER, was done for a period of five years from January 2014 to December 2018. The data was analysed for clinical and epidemiological characteristics of the patients.Results: A total of 307 patients visited the leprosy clinic during the study period. More than half patients (60.3%) were between 21-40 years age group. There were 213 males and 94 females with male female ratio of 2.3:1. 72.3% (222) patients were suffering from multibacillary leprosy and 27.7% (85) had paucibacillary disease. Borderline tuberculoid leprosy was the most common type found in 83 patients (27.1%). 16 cases (5.2%) of childhood leprosy (less than 14 years of age) were noted. A total of 214 patients (69.7%) were migrants.Conclusions: Despite of decline at global and national level, leprosy cases show gradual increase. The high proportion of total cases, MB cases, and grade 2 disability cases are warning signs. Continued efforts are required to manage and prevent the disease.

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Tinea pedis: a clinico mycological study

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20173917 ◽

2017 ◽

Vol 3 (3) ◽

pp. 323

Author(s):

Balakrishnan Thenmozhi Priya ◽

Chellam Janaki

Keyword(s):

Tinea Pedis ◽

Tertiary Care ◽

General Distribution ◽

Care Hospital ◽

Age Group ◽

Female Ratio ◽

Clinical Presentations ◽

Male Female Ratio ◽

Complete Physical Examination ◽

Local Examination

Background: To study the varied clinical presentations, the predominant etiological agent and incidence of tinea pedis in relation to sex, age group, occupation and aggravating factors among the patients. Also an attempt was made to know if any significant association is there with blood group and the occurrence of tinea pedis.Methods: A study was conducted among 75 patients who attended Mycology clinic in tertiary care hospital. Detailed history was taken along with complete physical examination and local examination. All cases of tinea pedis were first confirmed by KOH examination. Isolation of the agent was done in Modified SDA medium with cycloheximide. Differentiation of the species was done by culturing on corn meal agar.Results: Prevalence of tinea pedis infection was more common among males with male: female ratio of 2.26:1. The 21- 30 years age group was commonly affected by tinea pedis. The distribution of blood groups reflected the general distribution pattern of the population. Culture positivity was recorded in 81.3%.Conclusions: More incidences of bilateral involvement and recurrent episodes were noted among the shoe wearing population than in the non-shoe wearing population. Any patients diagnosed with tinea pedis should be screened for diabetes as implied by the outcome of the study. Infected toe nails may be the site of primary infection and fungal disease can spread to other body areas from these primary sites. Trichophyton rubrum happened to be the chief isolate.

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Prevalence and risk factors of Fungal Nasal Polyposis in Tertiary Care Hospital.

The Professional Medical Journal ◽

10.29309/tpmj/2020.27.02.3522 ◽

2020 ◽

Vol 27 (02) ◽

pp. 289-292

Author(s):

Ayub Musani ◽

Qaisar Sajjad ◽

Faheem Ahmed Khan ◽

Itrat Jawaid ◽

Hina Iqbal ◽

...

Keyword(s):

Risk Factors ◽

Nasal Polyps ◽

Nasal Polyposis ◽

Tertiary Care ◽

Total Duration ◽

Care Hospital ◽

Female Ratio ◽

Male Female Ratio ◽

History Of ◽

Study Setting

Objectives: To determine the prevalence of fungal rhinosinusitis in nasal polyps’ patients and to determine the risk factors of fungal rhino sinusitis. Study Design: Prospective study. Setting: Out patients and in patients department of Abbasi Shaheed Hospital and Karachi Medical and Dental College. Period: October 2014 to April 2017. Total duration of study was two and a half years. Material & Methods: In this study 221 cases were included who diagnosed nasal polyposis on clinical ground. Both sexes were included in this study. After informed consent complete history were taken and noted in pre designed Performa. Complete ENT and physical examination was done. Relevant investigations were advised as per requirement. Results: Total numbers of patients selected for this study were 221. The overall prevalence of fungal rhino-sinusitis was found in 90 patients (40.70%). Mostly patients belong to poor socio-economical status i.e. 59 (65.55%) followed by middle class 18 (20%) patients. Mean age was 30.16 +/_ 12.33. Male were 55 (61%) and female were 35 (38.8%) with male female ratio was 1:1.57. In risk factors, 36 (40%) patients were farmers while history of allergy was found in 35 patients (38.88%). Conclusions: Patients with nasal polyps should be properly evaluated for the early treatment of fungal rhino-sinusitis and also remove the risk factors to prevent the recurrence and unnecessary complications.

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Studying the clinic mycological pattern of the dermatophytic infection attending OPD in tertiary care hospital in eastern Uttar Pradesh and Bihar

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20180987 ◽

2018 ◽

Vol 4 (2) ◽

pp. 118 ◽

Cited By ~ 1

Author(s):

Anil Kumar Gupta ◽

Aayushi Mohan ◽

Santosh Kumar Singh ◽

Amit Kumar Pandey

Keyword(s):

Tertiary Care Hospital ◽

Tertiary Care ◽

Uttar Pradesh ◽

Common Species ◽

Outpatient Department ◽

Care Hospital ◽

Sample Collection ◽

Female Ratio ◽

Male Female Ratio ◽

Eastern Uttar Pradesh

Background: Superficial dermatophytic infection is infection of skin nail or hair with fungus. Nowadays, these fungal infection are at a rise and run a prolong course despite of treatment due to resistance to conventional antifungal agents. There is a felt need to conduct epidemiological study to know the change in the pattern and cause of widespread resistance. This study was aimed at identifying clinico-mycological pattern of dermatophytic infections in patients attending the dermatology outpatient department of a tertiary care hospital in eastern Uttar Pradesh and adjoining area.Methods: Patients with suspected dermatophytoses attending the outpatient department were enrolled in the study. A detailed history, clinical examination and sample collection for mycological examinations was done.Results: There were 500 patients recruited in the study, with a male: female ratio of 3:1. The most commonly affected age group was 20–30 years (35%). Tinea corporis et cruris was the most common type observed (31%). Potassium hydroxide positivity was seen in 390 samples (78%) and culture positivity was found in 350 samples (70%). The most common species identified was Trichophyton verrucosum (35.5%).Conclusions: There is a rise in dermatophytic infection caused by zoophilic species like Trichophyton verrucousum.

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Clinico-epidemiological study of leprosy from a North Indian tertiary care hospital

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20184234 ◽

2018 ◽

Vol 4 (4) ◽

pp. 518

Author(s):

Mohammad Adil ◽

Syed Suhail Amin ◽

Mohd Mohtashim ◽

Sabha Mushtaq ◽

Mehtab Alam ◽

...

Keyword(s):

Urban Areas ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Public Health Problem ◽

Lepromatous Leprosy ◽

Care Hospital ◽

Female Ratio ◽

Male Female Ratio ◽

One Year ◽

Epidemiological Characteristics

Background: Leprosy was eliminated as a public health problem in India in 2005. Yet, more than 60% of all new cases of leprosy are reported from India.Methods: A retrospective analysis of the records of patients attending the leprosy clinic of the Dermatology Out Patient Department was done for a period of one year from May 2017 to April 2018. The data was analysed for clinical and epidemiological characteristics of the patients.Results: A total of 225 patients visited the leprosy clinic during the study period. Almost half of all patients (47.1%) were aged between 21-40 years. Among the patients were 32 children (14.2%) below 16 years. There were 60 patients (26.6%) suffering from paucibacillary disease and 158 patients (70.2%) had multibacillary disease. Seven patients (3.2%) presented with other forms of leprosy like historic leprosy and pure neuritic leprosy. Borderline lepromatous leprosy was found to be the commonest subtype seen in 86 patients (38.2%). There were 152 males (67.6%) and 73 females (32.4%). The male female ratio was 2.08:1. A total of 118 patients (52.4%) were from rural background and 107 (47.6%) hailed from urban areas. Multibacillary disease was seen in 83.6% of the total females compared to 63.8% of males.Conclusions: Leprosy may be down but is not yet out. The high proportion of children diagnosed with leprosy is a warning regarding the active transmission of the disease in the community. Continued efforts are required to prevent the disease from making a resurgence.

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ASSESSMENT OF BURDEN OF ASPHYXIATED BABIES ACCORDING TOMETHOD OF RESUSCITATION AT TERTIARY CARE HOSPITAL

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v3i10.627 ◽

2019 ◽

Vol 3 (10) ◽

Author(s):

Dr. Satya Narayan Bijarnia ◽

Dr. Deveshwar Dev ◽

Dr. R K Gupta

Keyword(s):

Clinical Symptoms ◽

Perinatal Asphyxia ◽

Tertiary Care ◽

Birth Asphyxia ◽

Control Group ◽

Care Hospital ◽

Term Infants ◽

Female Ratio ◽

New Born ◽

Male Female Ratio

Background: Perinatal asphyxia is characterized among the fetus or new born due to deficiency of perfusion to the various organs of the fetus or new born. Birth asphyxia is the single most important perinatal cause of brain damage in term infants. When asphyxia is followed by an abnormal neonatal behavior a syndrome has been described known as hypoxic ischemic encephalopathy. Material & Methods: The new born with congenital malformation of CNS were excluded from the study. Each selected newborn was subjected to Apgar scoring at birth and assessment of gestational age. The Apgar scoring was done at one and five minutes after births and infants were categorized into mild, moderate and severe birth asphyxia according to Apgar score at 1 minute of age after birth Results: In the present study, on the basis of clinical symptoms we found that asphyxiated group males comprised 62% cases and females 38% cases male female ratio was 1.63:1.0 it is statistically in significant. as compared to control group where male female ratio was 2.59:1. In Mild and moderate asphyxia male preponderance was seen while in severe asphyxia the difference was not marked There was no statistically significant sex difference in birth asphyxia. Conclusion: We concluded from the present study that in resuscitation of mild and moderately asphyxiated babies Bag and Mask was used more frequently (40% and 82.5% respectively) and endotracheal tube with Ambubag was used more (75%) frequently for severely asphyxiated babes. Key words: asphyxia, resuscitation, Ambubag.

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Isolation of Morganella morganii and Providencia species from clinical samples in a tertiary care hospital

Infectious Disorders - Drug Targets ◽

10.2174/1871526520666200128162646 ◽

2020 ◽

Vol 20 ◽

Author(s):

Shiwani Sharma ◽

Prapti Bora ◽

Nidhi Singla ◽

Varsha Gupta ◽

Jagdish Chander

Keyword(s):

Clinical Laboratory ◽

Tertiary Care ◽

Liver Function Tests ◽

Clinical Samples ◽

Care Hospital ◽

Morganella Morganii ◽

Female Ratio ◽

Antimicrobial Susceptibility Profile ◽

Male Female Ratio ◽

Culture Positive

Introduction: The members of the tribe Proteeae, Morganella and Providencia are being increasingly recognized as important pathogens. The spectrum of disease caused by them is wide and in reported cases the mortality is high. Previously both these pathogens were considered to be rare pathogens as the potential to cause nosocomial transmission and infection was not much studied. But their phenomenal evolution and increase in multidrug-resistance (MDR) strains of these pathogens are posing a major threat toward public health throughout the world. Material and Methods: This present study was carried out from July 2018 to December 2018 on all the pus and body fluid samples that were received in Department of Microbiology. Samples were processed as per standard Microbiological guidelines and alsowere analyzed for their antimicrobial susceptibility profile as per Clinical Laboratory Standards Institute. Results: Out of 8425 samples received, 2140 were culture positive, amongst which 19 samples (0.89%) were positive for Providencia species (9) and Morganella morganii(10). The male : female ratio of these 19 patients was 2.8 : 1 and maximum patients (13) belonged to 20-60 years.As far as risk factors are concerned, maximum patients were diabetics (7) followed by abnormal liver function tests(6),concomitant UTI (6), history ofinvasive procedure (5), prior exposure to antibiotics (5) and urinary catheterization (4). About 6 were polymicrobial infections.Antibiotic susceptibility patterns revealed that Providencia strains were sensitive to ampicillin- sulbactum (77.7%) and amikacin (77.7%) while all Morganella strains were 100% sensitive to tobramycin and piperacillin tazobactam. Conclusion: This study heralds in a need for more research in this area as infections caused by these two pathogens are on the rise.Moreover,resistance to antimicrobials is also an increasingly common problem thus delaying the treatment and prognosis of disease.

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Retrospective Analysis of 52 Cases of Enteric Fever in a Tertiary Care Hospital in Dhaka City

Bangladesh Journal of Medicine ◽

10.3329/bjmed.v21i2.13614 ◽

2013 ◽

Vol 21 (2) ◽

pp. 71-73

Author(s):

M Mutanabbi ◽

KA Islam ◽

MA Helal ◽

HA Mamun ◽

M Quader ◽

...

Keyword(s):

Enteric Fever ◽

Descriptive Analysis ◽

Tertiary Care ◽

Salmonella Typhi ◽

Clinical Syndrome ◽

Delayed Response ◽

Care Hospital ◽

Female Ratio ◽

School Aged Children ◽

Male Female Ratio

Enteric fever remains a serious problem in developing countries. School aged children and young adults are mainly the sufferer. Salmonella typhi infection results in a clinical syndrome that varies widely in presentation; especially in new antibiotic era. Records of 52 enteric fever cases who were admitted to BSMMU, from July 2007 to June 2008 was reviewed and information was recorded in a prescribed form. Descriptive analysis was done through SPSS. Mean age was 6.7±4 years and male: female ratio was 1.2: 1. Most common presenting features were fever in 100% cases, abdominal pain 40% cases, vomiting 35% and diarrhea, constipation 10%cases. Hepatomegaly was present in 71% and splenomegaly in 52% cases. In our study32% of children were under 5 years; and the result is similar with some other studies. Typhoid fever is still a disease which is difficult to diagnose. In some cases of delayed response antibiotic may be required for longer duration where patients became afebrile after 10 days or more from starting antibiotic. DOI: http://dx.doi.org/10.3329/bjmed.v21i2.13614 Bangladesh J Medicine 2010; 21: 71-73

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Study of clinical profile of tuberculosis patients admitted in respiratory medicine ward at a tertiary care hospital in Marathwada

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20180003 ◽

2018 ◽

Vol 5 (1) ◽

pp. 68

Author(s):

Rakesh B. Bilagi ◽

Hafiz Deshmukh

Keyword(s):

Retrospective Study ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Clinical Profile ◽

Care Hospital ◽

Female Ratio ◽

Tuberculosis Patients ◽

Male Predominance ◽

Male Female Ratio ◽

One Year

Background: Tuberculosis is one of the most important cause of most of the respiratory diseases. It is estimated that about one-third of the world's population is infected with mycobacterium tuberculosis. It is important to know about the clinical profile of these patients. There are many studies which are done among OPD patients but fewer among indoor patients hence, the current study was planned.Methods: Retrospective study of the patients admitted in the inpatient department of the study area were taken as the sample size from May 2016 to April 2017, who were diagnosed as TB patients.Results: a retrospective study was conducted among admitted patients, which included data of one year. There was male predominance with male: female ratio of 2.89. major cause of admission was extrapulmonary causes. The HIV patients were more predisposed to extrapulmonary and diabetes than pulmonary tuberculosis.Conclusions: There is male predominance for admission cases. There is also increased cases of extrapulmonary TB admitted than pulmonary cases.

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