scholarly journals Age specific incidence of five major cancers in Nepal, 2012

2016 ◽  
Vol 6 (2) ◽  
pp. 565-573 ◽  
Author(s):  
Krishna Kanta Poudel ◽  
Zhibi Huang ◽  
Prakash Raj Neupane

Background: Population based cancer registry is inevitable to measure the indicators of cancer. This retrospective study was conducted to perform the age specific incidence and age standardized rate of cancer by sex, age and sites in Nepal, 2012. Materials and Methods: The data collected by hospital based National cancer registry programme of Nepal were used to calculate the age specific incidence of five major cancers by sex and sites. The age standardized rate of ten major cancers, both in males and females of 2012 was also performed.Results: The 70-74 years age group had the highest incidence rate (188.08) for men while for women the age group of 65-69 years had the highest incidence (140.61) per 100,000. For male, lung cancer had the highest incidence rate (4.45) whereas bladder had the lowest rate (0.98). Similarly for female, Cervix Uteri cancer had the highest incidence rate (5.35) whereas stomach had the lowest (1.06).Conclusion: This study presented that cancer was increased with age both in males and females. The leading cancer in males was bronchus and lung while in females it was cervix uteri.

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 216s-216s
Author(s):  
A. Korir ◽  
R. Gakunga ◽  
N. Okerosi ◽  
A. Karagu ◽  
N. Buziba ◽  
...  

Background: Population-based cancer registration represents the gold standard for the provision of information on cancer incidence in a defined population (Bray F, et. al, IARC Technical Report No. 43). In Kenya, the incidence and prevalence of cancer has not been well documented. The existing population-based cancer registries (PBCRs) cover less than 10% of Kenya's population. Kenya is made up of 47 administrative counties and has a population of over 45 million people. Aim: To establish a National Cancer Registry Program that will compile national data on incidence, mortality and trends of cancer in Kenya over time. Methods: Three functional PBCRs have been in existence covering 3 counties: Nairobi, Eldoret and Kisumu. Needs assessment was conducted in the 3 registries. Additional support and resources were provided. New registries were set up in different geographical regions of Kenya. A centralized office to host the national registry was established and equipped at the Centre for Clinical Research, Kenya Medical Research Institute. Sensitization and awareness activities targeting the leaders in the selected counties were undertaken. Similarly trainings and technical support of the regional registries were conducted. Data were collected on to case registration forms, coded using the International Classification of Diseases for Oncology (ICD-O); data entry, validation and analysis done using IARC software CanReg5. Results: Variations in cancer occurrence in the different counties were noted. However the leading cancers were somewhat similar in the 8 counties with prostate and esophageal cancers being the leading in men while breast and cervical cancer being top among women. These variations could provide understanding on causation of certain types of cancers. Data highlights the need to develop and expand intervention programs like HPV vaccination, screenings, early detection and early treatment. Governments' allocation of resources to cancer registries and surveillance programs is important as well as building partnerships. Conclusion: In countries with limited resources it is expensive to develop a national cancer registry covering the entire country. Our program demonstrates that a national cancer registry program can be established by setting up regional population-based cancer registries that covers a reasonable population of the entire country and aggregating the data in a centralized system. Population-based cancer registries are critical in generating data on burden of cancer in specified populations. These data should be used to inform effective cancer control programs and research.


2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 65s-65s
Author(s):  
F. Ramadhaniah ◽  
E. Suzanna ◽  
D. Triana ◽  
A. Kadir ◽  
T.H. Widyastoeti ◽  
...  

Background: Lung cancer surely increased particularly in developing country that has double burden of disease because of epidemiologic transition effected high incidence in productive age and premature death. Indonesia as a developing country has better life expectancy but there aren't national cancer control yet. National cancer registry as one of pivotal tools in priority setting of national cancer control. Aim: Epidemiology pattern of lung cancer based on National Cancer Registry to determine national cancer control programs. Methods: In 2016 Ministry of Health assigned 14 provinces (26 cities/districts) in Indonesia to enforce population-based cancer registry and Dharmais as a National Cancer Centre. All health facilities sent data to the National Referral Hospitals in each provinces which Canreg5 were used, year 2008-2012. Data from 14 National Referral Hospitals sent to Dharmais NCC for analysis. Results: Lung cancer posed in the first rank for male and the sixth rank for female by comparison 2:1. Peak incidence occurs in age group of 55 years for male meanwhile 50 years for female. However escalation of cases began in age group of 35 years for both sexes. Three provinces which have high incidence for lung cancer were Bali, South Sumatera and DKI Jakarta as capital city of Indonesia. Adenocarcinoma as the most common histology type. Despite most valid percentage and coverage from each province still quite low. Conclusion: Lung cancer become the first priority for cancer control program in male foremost three provinces. This issue highlighted and need further analysis to assess risk factor.


PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0246490
Author(s):  
Supot Kamsa-ard ◽  
Chalongpon Santong ◽  
Siriporn Kamsa-ard ◽  
Vor Luvira ◽  
Varisara Luvira ◽  
...  

Background Cholangiocarcinoma (CCA) is a leading cause of cancer death in northeastern Thailand. We reported on the incidence of CCA using only one method. In the current study, we used three different statistical methods to forecast future trends and estimate relative survival. Methods We reviewed the CCA cases diagnosed between 1989 and 2018 recorded in the population-based Khon Kaen Cancer Registry (KKCR). Annual percent change (APC) was calculated to quantify the incidence rate trends using Joinpoint regression. Age-period-cohort models (APC model) were used to examine the temporal trends of CCA by age, calendar year, and birth cohort. We projected the incidence of CCA up to 2028 using three independent approaches: the Joinpoint, Age-period-cohort, and Nordpred models. Survival assessments were based on relative survival (RS). Results The respective APC in males and females decreased significantly (-3.1%; 95%CI: -4.0 to -2.1 and -2.4%; 95%CI: -3.6 to -1.2). The APC model—AC-P for male CCA—decreased according to a birth-cohort. The CCA incidence for males born in 1998 was 0.09 times higher than for those born in 1966 (Incidence rate ratios, IRR = 0.09; 95%CI: 0.07 to 0.12). The relative incidence for female CCA similarly decreased according to a birth-cohort (IRR = 0.11; 95%CI: 0.07 to 0.17). The respective projection for the age-standardized rate for males and females for 2028 will be 7.6 per 100,000 (102 patients) and 3.6 per 100,000 (140 patients). The five-year RS for CCA was 10.9% (95%CI: 10.3 to 11.6). Conclusion The incidence rate of CCA has decreased. The projection for 2028 is that the incidence will continue to decline. Nevertheless, the survival of patients with CCA remains poor.


2020 ◽  
pp. 1063-1075 ◽  
Author(s):  
Prashant Mathur ◽  
Krishnan Sathishkumar ◽  
Meesha Chaturvedi ◽  
Priyanka Das ◽  
Kondalli Lakshminarayana Sudarshan ◽  
...  

PURPOSE The systematic collection of data on cancer is being performed by various population-based cancer registries (PBCRs) and hospital-based cancer registries (HBCRs) across India under the National Cancer Registry Programme–National Centre for Disease Informatics and Research of Indian Council of Medical Research since 1982. METHODS This study examined the cancer incidence, patterns, trends, projections, and mortality from 28 PBCRs and also the stage at presentation and type of treatment of patients with cancer from 58 HBCRs (N = 667,666) from the pooled analysis for the composite period 2012-2016. Time trends in cancer incidence rate were generated as annual percent change from 16 PBCRs (those with a minimum of 10 years of continuous good data available) using Joinpoint regression. RESULTS Aizawl district (269.4) and Papumpare district (219.8) had the highest age-adjusted incidence rates among males and females, respectively. The projected number of patients with cancer in India is 1,392,179 for the year 2020, and the common 5 leading sites are breast, lung, mouth, cervix uteri, and tongue. Trends in cancer incidence rate showed an increase in all sites of cancer in both sexes and were high in Kamrup urban (annual percent change, 3.8%; P < .05). The majority of the patients with cancer were diagnosed at the locally advanced stage for breast (57.0%), cervix uteri (60.0%), head and neck (66.6%), and stomach (50.8%) cancer, whereas in lung cancer, distant metastasis was predominant among males (44.0%) and females (47.6%). CONCLUSION This study provides a framework for assessing the status and trends of cancer in India. It shall guide appropriate support for action to strengthen efforts to improve cancer prevention and control to achieve the national noncommunicable disease targets and the sustainable development goals.


Author(s):  
SHAIK ASHA BEGUM ◽  
JOSHNA RANI S ◽  
AHMADI BANU ◽  
AVULA PAVANI ◽  
VEENA YERUVA

The deliberate assortment of information on cancer growth was performed by different populace-based disease vaults (population-based cancer registries [PBCRs]) and clinic-based cancer growth libraries (hospital-based cancer registries [HBCRs]) across India under the National Cancer Registry Program–National Center for Disease Informatics and Research of Indian Council of Medical Research since 1982. This survey analyzed the malignant growth occurrence, designs, patterns, projections, and mortality from 28 PBCRs and furthermore the stage at introduction and kind of therapy of patients with disease from 58 HBCRs (n=667,666) from the pooled investigation for the composite time frame 2012–2016. Time patterns in cancer growth rate were created as yearly percent change from 16 PBCRs (those with at least 10 years of consistent great information accessible) utilizing Joinpoint relapse. Aizawl locale (269.4) and Papumpare region (219.8) had the most elevated age changed occurrence rates among guys and females, separately. The extended number of patients with disease in India is 1,392,179 for the year 2020, and the basic five driving destinations are cancer, lung, mouth, cervix uteri, and tongue. Patterns in disease frequency rate showed an expansion on the whole locales of cancer in both genders and were high in Kamrup Metropolitan (yearly percent change, 3.8%; p<0.05). Most of the patients with cancer were analyzed at the privately progressed stage for cancer (57.0%), cervix uteri (60.0%), head and neck (66.6%), and stomach (50.8%) disease, while in cellular breakdown in the lungs, far off metastasis was dominating among guys (44.0%) and females (47.6%). This audit gives a system to surveying the status and patterns of cancer growth in India. It will manage proper help for activity to fortify endeavors to improve cancer growth avoidance and control to accomplish the public non-communicable illness targets and the reasonable advancement objectives.


Author(s):  
Krishna Prasad Subedi ◽  
Laxmi Narayan Singh ◽  
Binay Thakur ◽  
K K Pradhananga ◽  
Chin Bahadur Pun

<p>Now more and more cancers are being diagnosed in Nepal. But it is hard to assess the burden of cancer in national context based on available data. The available hospital based information neither shows the magnitude of the problem nor there has been any community-based study in the past. First time in Nepal population based Cancer registry (PBCR) was started in 15 districts of different geographical region i.e. Himal, Pahad, Tarai, which covered the 25.8% of total population of the nation. Therefore, outcome of this study can be used to infer an overall situation of cancer in Nepal.</p> <p>In the year 2013-14, cancer cases were reported from data source institutions for the process of population based cancer registration. Among them the cases were verified by name, age, sex and disease i.e. topography/morphology. Cases were collected</p> <p>from projected areas and multiple entry were excluded from data base and total 5089 (2469+2620) cases were analyzed for the purpose. The mean age at diagnosis in 2013 was 53.9 years and 53.2 years in 2014, whereas; mean age in average for 2013-14 was 53.6 years.</p> <p> In the year 2013, the most frequent form of cancer for both sexes was bronchus & lung 15.7%, followed by cervix uteri 11.0%, and breast 7.6%. Among the female cases cervix uteri cancer 20.0% was the most frequent, followed by breast 13.5% and bronchus & lung cancer 12.9%. Similarly, bronchus & lung cancer 15.8% was the most common cancer among males, followed by stomach 6.1% and larynx cancer 4.3%. The most prevalent age group in male 70-74 years 19.9%, while in female it was in same age group 70-74 years 13.4%. </p> <p>In the year 2014, the leading sites of cancer for both sexes was bronchus & lung 13.7%, followed by cervix uteri 10.5%, and breast 9.5%. Among the female cases cervix uteri cancer 18.0% was the most frequent, followed by breast 15.5% and bronchus & lung cancer 11.8%. Similarly, bronchus & lung cancer 16.5% was the most common cancer among males, followed by stomach 7.4% and larynx cancer 5.3%. The most prevalent age group in male 70-74 years 11.3%, while in female it was in same age group 60-64 years 12.3%. The present data provide population based cancer burden in Nepal. According to findings, cancer of bronchus& lung was the most common topography of cancer followed by cervix uteri and breast for both sex in 2013-14.</p>


2020 ◽  
Vol 11 ◽  
pp. 215013272098505
Author(s):  
Andrew T. Askow ◽  
Jacob L. Erickson ◽  
Andrew R. Jagim

Objectives Concussions and mild traumatic brain injuries are important medical issues, particularly among youth as the long-term health consequences of these injuries can become increasingly problematic. The purpose of this study was to examine recent trends in diagnosed concussions among pediatric patients in a large health care system. Methods This was a retrospective, population-based epidemiology study design that queried all patient files (pediatrics included) using electronic medical health records and further stratified patients based on type of concussion, age, sex, and year from 2013 to 2018. Results Electronic health records from a cohort of 8 832 419 (nmales = 4 246 492; nfemales = 4 585 931) patient visits were assessed for concussion diagnosis and filtered for those whose concussive event led to a loss of consciousness (LOC) or not (nLOC). Of these patients, 12 068 were diagnosed with a concussion (LOC = 3 699; nLOC = 8 369) with an overall incidence rate of 1.37 concussions per 1000 patients. Overall, the number of patients diagnosed with a concussion increased by 5063 (LOC = 1351; nLOC = 3712) from 2013 to 2018. Males and females presented with similar rates of concussions 5919 (49.05%) and 6149 concussions (50.95%), respectively. Of total diagnosed concussions, 4972 (LOC = 815; nLOC = 4157) were under the age of 18 and represented 41.2% of all diagnosed concussions with an incidence rate of 6.79 per 1000 patients. Conclusion The number of concussions diagnosed appear to be on the rise with the largest number of concussions being diagnosed in those under the age of 18. Future studies should seek to determine primary causality and the long-term health implications of concussions with or without LOC.


Author(s):  
Robert G. Stirling ◽  
Peta McLaughlin ◽  
Meera Senthuren ◽  
Sue Evans ◽  
D N. Watkins ◽  
...  

2019 ◽  
pp. 1-10 ◽  
Author(s):  
Aleyamma Mathew ◽  
Preethi Sara George ◽  
Kunnambath Ramadas ◽  
Beela Sarah Mathew ◽  
Aswin Kumar ◽  
...  

PURPOSE Lower socioeconomic status is associated with inferior cancer survival in high-income countries, but whether this applies to low- and middle-income countries is not well described. Here, we use a population-based cancer registry to explore the association between educational level and stage of cancer at diagnosis in South India. METHODS We used the Trivandrum District population-based cancer registry to identify all cases of breast and cervical cancer (women) and oral cavity (OC) and lung cancer (men) who were diagnosed from 2012 to 2014. Educational status—classified as illiterate/primary school, middle school, or secondary school or higher—was the primary exposure of interest. Primary outcome was the proportion of patients with advanced stage disease at diagnosis defined as stage III and IV (breast, cervix, or OC) or regional/metastatic (lung). RESULTS The study population included 4,547 patients with breast (n = 2,283), cervix (n = 481), OC (n = 797), and lung (n = 986) cancer. Educational status was 22%, 19%, and 26% for illiterate/primary, middle, and secondary school or higher, respectively. Educational status was missing for 33% of patients. The proportion of all patients with advanced stage disease was 37% (breast), 39% (cervix), 67% (OC), and 88% (lung). Patients with illiterate/primary school educational status were considerably more likely to have advanced breast cancer (50% v 39% v 36%; P < .001), cervix cancer (46% v 43% v 24%; P = .002), and OC cancer (77% v 76% v 59%; P < .001) compared with patients with higher educational levels. The proportion of patients with advanced lung cancer did not vary across educational levels (89% v 84% v 88%; P = .350). CONCLUSION A substantial proportion of patients in South India have advanced cancer at the time of diagnosis. This is particularly true among those with the lowest levels of education. Future health awareness and preventive interventions must target less-educated communities to reduce delays in seeking medical care for cancer.


2019 ◽  
Author(s):  
Mariela Garau ◽  
Carina Musetti ◽  
Rafael Alonso ◽  
Enrique Barrios

Background: Uruguay is the southamerican country which has the highest cancer incidence and mortality rates. The National Cancer Registry collects data on cancer cases nationwide since 1989 and has reached high quality standards in the last decades. This is the first report on incidence trends. Methods: Data from the National Cancer Registry of all new cases of invasive cancer from twelve sites diagnosed in 2002-2015 was analyzed. Age-standardized rates were calculated. Trends of incidence rates were analyzed using joinpoint regression models. Results For both, men and women, incidence rates trends for all cancer sites, colo-rectal and bladder cancer remained stable. Esophageal and gastric cancers descend while Thyroid and kidney cancer incidence increased. In men lung cancer decreased; testicular cancer increased, and prostate cancer increased at the beginning of the period and decreased in the final years. In women; lung cancer increased, breast cancer remained stable and cervical cancer presented a significant decline from 2005 to 2010 and reached a plateau since then. Conclusion: Cancer incidence dynamics are complex and affected not only by Public Health policies such as tobacco control, vaccination and screening programs, but also by environmental and life style changes and the attitude of the medical community towards the application of diagnostic and therapeutic tools. The aim of this paper is to analyze cancer incidence time trends in the country and provide possible explanations to them.


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