Frequency of electro-cardiographic changes in patients of acute organophosphate poisoning at tertiary care hospital Larkana, Pakistan

2017 ◽  
Vol 14 (2) ◽  
pp. 5-8
Author(s):  
Munawar Hussain Soomro ◽  
Mansoor Magsi ◽  
Rahim Baig ◽  
Mohammad Aslam Soomro

Background and Aims: The organophosphate (OP) poisoning is one of the important preventable public health problems in developing countries. It is estimated that OP pesticide self-poisoning kills around 200,000 people every year. The aim of the study was to determine the frequency of electrocardiographic (ECG) changes in acute OP poisoning at tertiary care hospital Larkana, Pakistan.Methods: It was an observational retrospective study of the patients who were diagnosed with acute OP poisoning during the period of four years January 2012 to December 2015 at medical emergency department, Shaheed Mohtarma Benzir Bhutto Medical University Hospital Larkana, Pakistan. A sample of 223 patients between 16-45 years with definite history of OP ingestion, were included in study. Patients with the history of cardiac disease, diabetes mellitus, hypertension, chronic renal failure and electrolyte imbalance were excluded.Results: Mean age was 29.61 ± 8.656 years with range of 16-45 years. Duration of OP ingestion ranged from 30 to 300 minutes with mean of 167.53 ± 45.26 minutes. Sixty five percent patients were in their 3rd and 4th decades of life. Males were 122 (54.71%) while 101 (45.29%) were females. ECG changes found in 145 (65.02%) with tachycardia and bradycardia was 85 (38.1%) and 60 (26.9%) respectively. The ST elevation was noted in 59 (26.5%), depression in 50 (22.4%), T wave changes observed in 51 (22.9%) patients. QTc interval was prolonged in 129 (57.85%).Conclusion: ECG changes are frequent in OP patients. QTc interval followed by sinus arrhythmias were most common changes observed. ECG should be done in all the patients who present with OP poisoning.Nepalese Heart Journal 2017; Vol 14(2), 5-8

2020 ◽  
Vol 27 (12) ◽  
pp. 2696-2702
Author(s):  
Iram Aslam ◽  
Uzma Manzoor ◽  
Saadia Bano ◽  
Uzma Shahzad ◽  
Saima Qureshi ◽  
...  

Objectives: To determine prevalence of Hepatitis C among pregnant female visiting a tertiary care hospital. Study Design: Observational study. Setting: Independent University Hospital Faisalabad. Period: 1-1-2018 to 31-12-2018. Material & Methods: Total 4210 pregnant patients visited during this time period. Results: During the study period i-e from 1-1-2018 to 31-12-2018, total 4210 obstetric patients visited Independent University Hospital. Among them 463 were Anti HCV +with % age of 10.9. Our study showed that 28 patients (6%) were <19 yrs of age, 35 patients (7%) were 20 to 25 yrs. 48 patients (10%) were 26 to 29 yrs.151 patients (32%) were 30 to 35 yrs of age. 201 patients (43%) were more than 35 yrs. Our result has shown that most of the infected patients were having their 5th or more pregnancy (202%). 182 patients (39%) were G4 or G5.47 patients (10%) were having their 2nd or 3rd pregnancy while only 32 (6%) primigravidas had this infection. Our study has shown that 325(70%) patients were of rural background while 135(29%) patients belonged to urban areas. When these Hepatitis C+ve patients were analyzed for risk factors, 91 had some dental manipulation in the past (19%), 104 had history of previous blood transfusion or some parental infusions (22%) 32 patients (6.9%) had their partners infected with Hepatitis C. 161 patients (34%) had history of some surgery or previous vaginal delivery at some centre where sterilization was not standardized. 75 patients (16%) had no identifiable risk factor. Conclusion: The prevalence of Hepatitis C is quite high in pregnant patients of Faisalabad. There is a dire need to address the factors involved in transmission of disease. Health policies should be revised to decrease the spread of this virus. Increased awareness is needed among the people regarding its transmission and early diagnosis so that curative measures should be timely taken to avoid the dreadful complications of Hepatitis C.


2020 ◽  
Vol 13 (2) ◽  
pp. 69-72
Author(s):  
Manchala Pratap Reddy ◽  
◽  
Pogula Nagarjuna Reddy ◽  
G.Vijaya Kumar ◽  
◽  
...  

2021 ◽  
Vol 15 (9) ◽  
pp. 2451-2453
Author(s):  
Shahid Iqbal ◽  
Muhammad Fareed Khan ◽  
Raja Imtiaz Ahmed ◽  
Shahab Saidullah ◽  
Nisar Ahmed ◽  
...  

Objective: To find out the pattern of CHD and associated risk factors among children presenting at a tertiary care hospital. Study Design: A case-control study. Place and Duration of the Study: The Department of Pediatrics and Department of Cardiology, Sheikh Khalifa Bin Zayed Al Nahyan Hospital, Rawlakot from July 2020 to June 2021. Material and Methods: A total of 207 children of both genders, screened by ECG along with chest x-ray and further confirmed with the diagnosis of CHD through echocardiography were enrolled as cases. Same number of healthy controls (n=207) were recruited from immunization center of the study institution. Among cases, types of CHD were noted. For cases and controls, demographic, antenatal and maternal risk factors including maternal age, gender of the child, history of consanguinity, history of febrile illness in pregnancy, use or multi-vitamin or folic acid in pregnancy, bad obstetrical history and maternal diabetes mellitus were noted. Results: In a total of 414 children (207 cases and 207 controls), there were 219 (53.8%) male. In terms of CHD types among cases, VSD was the most noted in 62 (30.0%), ASD 35 (16.9%), TOF 33 (15.9%) and PDA in 30 (14.5%). Cases were found to have significant association with younger age (78.3% cases below 1 year of age vs. 64.7% in controls, p=0.0085), bad obstetrical history (p=0.0002), history of febrile illness in 1st trimester of pregnancy (p=0.0229) and lack of multivitamins and folic acid in the 1st trimester of pregnancy (p=0.0147). Conclusion: Majority of the children with CHDs were male and aged below 1 year. VSD, ASD, TOF and PDA were the most frequent types of CHD. Younger age, bad obstetrical history, history of febrile illness in 1st trimester of pregnancy and lack of multivitamins and folic acid in the 1st trimester of pregnancy were found to have significant association with CHDs among children. Keywords: Congenital heart disease, echocardiography, ventricular septal defect.


PLoS ONE ◽  
2016 ◽  
Vol 11 (12) ◽  
pp. e0168729 ◽  
Author(s):  
Takeo Kurita ◽  
Taka-aki Nakada ◽  
Rui Kawaguchi ◽  
Koichiro Shinozaki ◽  
Ryuzo Abe ◽  
...  

2015 ◽  
Vol 6 (2) ◽  
pp. 45-47
Author(s):  
Mirza Md Ziaul Islam ◽  
M Mizanur Rahman

Cerebral malaria (CM) is the most severe neurological presentation of acute falciparum malaria. It is a medical emergency, the hallmark of which is the presence of coma probably due to diffuse encephalopathy. A compromised microcirculation with sequestration of parasitized erythrocytes is central to the pathogenesis of cerebral malaria. The death is unacceptably high even with effective antimalarials in tertiary care hospital. The mainstay of treatment of cerebral malaria include prompt diagnosis and early institution of effective antimalarial therapy, recognition of complications, and appropriate supportive management in an ICU. Neurological sequlae are increasingly recognized, but further research on the pathogenesis of coma and neurological damage is required to develop other ancillary treatmentsNorthern International Medical College Journal Vol.6(2) 2015: 45-47


2021 ◽  
Vol 7 (4) ◽  
pp. 315-319
Author(s):  
U Ketan Raju ◽  
Hanamant G Bobade ◽  
Anil Mishra

Dermatophytes are aerobic fungi that produce proteases that digest keratin and allows colonization, invasion and infection of the stratum corneum of the skin, the hair shaft, and the nail. This study was an attempt on the part of the author to find out the incidence and various clinico-epidemiological characteristics of Dermatophytosis in skin OPD of Tertiary care Hospital, B.K.L.W.R.M.C., Dervan. The study was carried on 2444 patients of Dermatophytosis attending the OPD, out of which 49.79% of the cases were Tinea Cruris (TC). The age group of 11-20 years showed maximum prevalence of Dermatophytosis (22.17%). 58% of the patients had diffuse lesions. Body involvement was seen in 87% of cases. Itching was the most common condition associated with Dermatophytosis. 35% of the patients reported with family history of Tinea Cruris.Circumscribed variety of TC was found to be most common variant mostly observed in 2and 4 decade, with a male preponderance. Groin was the most common site with multiple lesions. Nail changes was most commonly associated with TC.


2021 ◽  
Vol 8 (4) ◽  
pp. 308-312
Author(s):  
Pendru Raghunath ◽  
LN Rao Sadanand

Streptococci are gram positive cocci arranged in chains and are part of normal flora of humans and animals. The present study is carried out to determine the prevalence and risk factors for the carriage of beta-haemolytic streptococci (BHS) among women visiting Dr. VRK Women’s Teaching Hospital & Research Centre, Hyderabad. Vaginal swabs were collected from 250 patients attending outpatient department (OPD) of Dr. VRK Women’s Teaching hospital. Swabs were inoculated onto 5% sheep blood agar plates and incubated for 24 h at 37°C in a candle jar. BHS isolates were phenotypically identified by standard microbiological techniques, all the isolates presumptively identified as BHS were tested for Bacitracin susceptibility. Sensitive isolates were presumptively identified as GAS and resistant isolates were identified as non-group A BHS (NGABHS). Presumptively identified GAS & NGABHS isolates were serogrouped by Lancefield grouping using a commercially available latex agglutination test. BHS were isolated from 12.4% of samples. As many as 12 BHS isolates were identified as GAS and 19 were identified as NGABHS. Ten of nineteen were identified as group B (GBS), 4 (12.9%) were identified as group C (GCS) and 5 (16.12%) were identified as group G (GGS). Among six clinical groups, the prevalence of GAS is highest i.e. 7.5% in female patients visiting Gynaecology OPD with history of white discharge. Prevalence of NGABHS was more among post insertion (18%) IUCD group compared to pre insertion (8%) IUCD group. GBS were isolated from 7% of samples from IUCD group and 4% of samples from prostitutes.This study reports the prevalence of BHS among women visiting a tertiary care hospital in Hyderabad. This study also identified certain risk factors such as IUCD usage and working as a FSW are associated with the increased prevalence of NGABHS especially GBS.


2020 ◽  
Vol 58 (232) ◽  
Author(s):  
Meenakshi Basnet ◽  
Bibek Ghimire ◽  
Akriti Shrestha ◽  
Gyan Raj Aryal

Introduction: Epistaxis is a common medical emergency with 5% to 15% of patients admitted for epistaxis will require surgical management as nasal packing has high failure rates. A modern endoscopic technique like Endoscopic Sphenopalatine Artery Ligation has increased in popularity for managing intractable posterior epistaxis. It has less complication and a high success rate. The study conducted to estimate the success rate of Endoscopic Sphenopalatine Artery Ligation of refractory posterior epistaxis among admitted patients in a tertiary care hospital. Methods: This is a descriptive cross-sectional study conducted from June 2019 to June 2020 at the Department of Otorhinolaryngology, Nobel Medical College and Teaching Hospital among the patient with refractory posterior epistaxis with the help of retrospective data. A convenient sampling method was used. These patients underwent endoscopic sphenopalatine artery cauterization for recurrent/intractable posterior epistaxis. Ethical clearance was taken from the Institutional Review Board. Data were analyzed in Statistical Package for the Social Sciences. Results: Out of the total patient with refractory posterior epistaxis who underwent Endoscopic Sphenopalatine Artery Ligation, the overall success rate was 39 (95.12%). Among them, 25 (60.97%) males and 16 (39.02%) females underwent endoscopic sphenopalatine artery ligation. Twenty (48.78%) of them were unilateral whilst 21 (51.21%) were bilateral disease. About 2 (4.8%) cases had re-bleeding within 48 hours which was managed conservatively. Hypertension was found to be the most common comorbid condition followed by diabetes, chronic kidney. Conclusions: From our study, we conclude that the success rate for Endoscopic Sphenopalatine Artery Ligation in a patient with refractory posterior epistaxis was high.


BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S293-S293
Author(s):  
Chathurie Suraweera ◽  
Iresha Perera ◽  
Priyanka Rupasinghe ◽  
Janith Galhenage

AimsThe study describes the prevalence and associated socio-demographic variables of psychoactive substance use among male supportive staff members at a tertiary care hospital in Sri Lanka.MethodA cross-sectional descriptive study was carried out among male supportive staff members of a tertiary care hospital in Colombo District, Sri Lanka by using a self-administered anonymous questionnaire. Participants were recruited using stratified cluster sampling in thirteen overseer divisions of the hospital. Anonymous questionnaires were collected into a sealed box and analysed using Statistical Package for Social Sciences 20.ResultThe mean age of the 404 male staff members who participated in the study was 38.78(SD = 10.90) years and 71.5% were married. Among them 202 (49.1%) were educated up to grade 6-11 and 30 of them has had encounters with law in the past. Thirty of participants had history of psychoactive substance use in the family. Alcohol was used more than once a month by 127(30.9%) and more than once a week by 19(4.6%) individuals. Among other substances, tobacco, beetle and beedi were used by 104(25.3%), 78(19.0%) and 18(4.4%) respectively at least once a month. Further, 22(5.3%), 20(4.8%), 7(1.7%) and 7(1.7%) participants used Mava, Cannabis, Methamphetamine and Thool respectively at least less than once a month. Heroin, Tramadol and Morphine were used by two individuals at least less than once a month. Among substance using participants, 132 wished to cut down their habit. Most commonly identified (14.1%) adverse consequence was financial issues secondary to psychoactive substance use. Eleven (4.5%) staff members used the substance at hospital. Alcohol use was associated with age more than 35 years (p = 0.039) and history of forensic involvement (p = 0.038). Tobacco(p = 0.000), beetle (p = 0.056), Cannabis (p = 0.000) and mava (p = 0.015) use were significantly associated with positive forensic history. Supportive staff members’ alcohol and cannabis use was associated with tobacco (p = 0.000, p = 0.000) and beetle use (p = 0.001, p = 0.049). Mava use was associated with alcohol (p = 0.060) use in addition to tobacco (p = 0.020) and beetle use (p = 0.008).Binomial logistic regression revealed alcohol use and beetle use were associated with the number of children in family and above associations.ConclusionCommonest psychoactive substance consumed by supportive staff members were alcohol, tobacco, beetle, Cannabis and Mava in descending order of frequency. Forensic history was significantly associated with substance use. True prevalence of substance use can be higher than these values.


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