scholarly journals Thyroid function test in abnormal uterine bleeding

2018 ◽  
Vol 12 (2) ◽  
pp. 74-78
Author(s):  
Pramod Kattel
Keyword(s):  
Thyroid Function ◽  
Thyroid Dysfunction ◽  
Pap Smear ◽  
Abnormal Uterine Bleeding ◽  
Thyroid Function Test ◽  
Endometrial Biopsy ◽  
Uterine Bleeding ◽  
Pathological Examination ◽  
Overt Hypothyroidism ◽  
Function Test

Aims: To evaluate and detect the thyroid dysfunction in patients with abnormal uterine bleeding (AUB) from puberty to menopause.Methods: This is an observational descriptive study of 90 patients of abnormal uterine bleeding at Paropakar Maternity and Women’s Hospital, Kathmandu from 17th January 2016 to 16th January 2017. Besides thyroid function test Pap smear, endometrial biopsy and histo-pathological examination of uterus following hysterectomy was done in selected cases.Results: The incidence of AUB was 6.2 % with mean age of 37 years. The most common presenting complaint was menorrhagia (36.7%) followed by metrorrhagia (23.3%). Thyroid dysfunction accounted for 20% of AUB with major share occupied by subclinical hypothyroidism (11%) and least by hyperthyroidism (1%). The most common association of thyroid dysfunction with AUB was overt hypothyroidism (27.3%) with menorrhagia. Non-structural cases of AUB accounted for 30.4% of thyroid dysfunction.Conclusions: This study shows that thyroid dysfunction plays significant role for AUB so it is wise enough to perform TFT on routine basis in order to avoid unnecessary hormonal treatment with Estrogen, Progesterone or their combination and even the hysterectomies.

scholarly journals Study of association of thyroid disorders with abnormal uterine bleeding

2017 ◽  
Vol 6 (6) ◽  
pp. 2302
Author(s):  
Runoo Ghosh ◽  
Rakesh R. Patel
Keyword(s):  
Thyroid Dysfunction ◽  
Abnormal Uterine Bleeding ◽  
Thyroid Function Test ◽  
Uterine Bleeding ◽  
Age Group ◽  
Central Laboratory ◽  
Fertile Period ◽  
Blood Samples ◽  
Common Cause ◽  
Function Test

Background: Abnormal uterine bleeding from the vagina that is usually occurred when ovary do not release egg and if it occurred during fertile period leads to various complication like anemia, Infertility etc. and among all causes one of the most common cause of abnormal uterine bleeding is disturbance in level of Thyroid hormones.Methods: 100 female Patients of age group between 20-45 having complain of Abnormal uterine bleeding visited at Gynec OPD of our institute were included in this study. fasting blood samples was taken from all participants and samples were analyzed for Thyroid function test (TSH, T3, T4) at central laboratory of our hospital. Obtained data was analyzed statistically by using prizam software.Results: The bleeding abnormality that is found most of the women is polymenorrhaggia and menorrhaggia. 32% of patients who were studied had thyroid dysfunction, of which 18% of patients had subclinical hypothyroidism, 11% of patients had hypothyroidism and only 3% of patients had hyperthyroidism.Conclusions: Present study concludes that thyroid dysfunction should be considered as an important etiological factor for menstrual abnormality especially during fertile period.

scholarly journals Thyroid function in abnormal uterine bleeding

2019 ◽  
Vol 8 (6) ◽  
pp. 2270
Author(s):  
Ruthvika Kundoor ◽  
Burri Sandhya Rani
Keyword(s):  
Thyroid Function ◽  
Abnormal Uterine Bleeding ◽  
Thyroid Function Test ◽  
Uterine Bleeding ◽  
Reproductive Age ◽  
Age Group ◽  
Clinically Normal ◽  
Biochemical Evaluation ◽  
Menstrual Pattern

Background: AUB is any abnormal uterine bleeding in the absence of any palpable pelvic pathology and demonstrable extra genital causes. AUB is responsible for 10% of gynaecological complaints. Thyroid hormone is very important to affect the menstrual pattern. The objective of this study was to evaluate thyroid function test in women with AUB and to assess the menstrual pattern in women with thyroid dysfunction.Methods: The present study was conducted in the Department of Obstetrics and Gynecology, Laxmi Narasimha Hospital, Hanamkonda, Hyderabad, Telangana, India 80 women of reproductive age group between 15-45 years women with menstrual disorders like menorrhagia, oligomenorrhea, hypomenorrhea, polymenorrhea, metrorrhagia, and amenorrhea. Quantitative determination of T3, T4, and TSH by CLIA estimated in autoanlyser.Results: About 80 women participated in the study in which Most of the subjects belong to 26-30 years of age group. Maximum patients i.e. 41 (51.2%) patients were para one to 2. Commonest cause bleeding pattern was menorrhagia 41.25%. 15 apparently normal patients with AUB belonged to the category of subclinical hypothyroidism (15%). Hormonal levels revealing profound hypothyroidism in patients without any symptoms was present in only 10% of cases. 2.5% of cases had hyperthyroidism though they were clinically normal. Patients who were sub-clinically hypothyroid were maximally presenting as polymenorrhoea (50%) and menorrhagia (12.1%) and only 6.27% of patients had oligomenorrhoea. Patients who were profound hypothyroid were predominantly having polymenorrhagia (83.3%) and (62.5%) of patients had oligomenorrhoea.Conclusions: So, biochemical evaluation of thyroid functioning should be made mandatory in all provisionally diagnosed cases of AUB to detect thyroid dysfunction.

Abnormal Uterine Bleeding (AUB) and Thyroid Function in Chhattisgarh

2017 ◽  
Vol 7 (2) ◽  
pp. 29-41
Author(s):  
Mukund Tiwari ◽  
Dr. Sarita Agrawal ◽  
Subarna Mitra
Keyword(s):  
Clinical Practice ◽  
Menstrual Cycle ◽  
Thyroid Gland ◽  
Thyroid Function ◽  
Thyroid Dysfunction ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Thyroid Disorder ◽  
Study Participants

Abnormal function of thyroid gland is associated with a disturbance in the menstrual cycle. However, in clinical practice, thyroid dysfunction is frequently overlooked as a possible etiology and therefore, the importance to investigate thyroid function in asymptomatic cases is under- recognized in India. Treating thyroid dysfunction in such cases can reverse the menstrual abnormality, thus avoiding unnecessary hormonal therapy or in long term, hysterectomy. This article is intended to determine the prevalence of overt and subclinical forms of hypothyroidism/hyperthyroidism among women with abnormal uterine bleeding (AUB) in a known iodine-deficient state of India, Chhattisgarh. Moreover, the aims included to characterize the types of menstrual abnormality with thyroid dysfunction in study participants. The present study found a prevalence of thyroid dysfunction in one out of five cases of menstrual abnormality, most common dysfunction being hypothyroidism. An appreciable proportion of thyroid disorder was found in patients with menorrhagia, oligomenorrhea, polymenorrhea and amenorrhea.

scholarly journals Prevalence and complications of Hypothyroidism during pregnancy in western Nepal

2014 ◽  
Vol 3 (1) ◽  
pp. 48-50 ◽  
Author(s):  
TL Upadhyaya ◽  
A KC ◽  
S Paudel
Keyword(s):  
Thyroid Function ◽  
Care Center ◽  
Tertiary Care ◽  
College Teaching ◽  
Thyroid Function Test ◽  
Overt Hypothyroidism ◽  
Medical College ◽  
Study Results ◽  
Function Test ◽  
Entire Pregnancy

Background: This study was designed to know the prevalence of hypothyroidism during pregnancy in western part of Nepal and its potential complications. Methods: One Hundred seven pregnant cases from Gandaki Medical college teaching hospital and Diabetes thyroid and Endocrinology care center, two of the tertiary care centers in Pokhara were enrolled in the study from the year 2011 January to 2012 December. Detailed history and physical examination was done. Thyroid Function test (FT3, FT4 andTSH) were performed after the confirmation of pregnancy. Patients were followed up during entire pregnancy. Seven patients dropped out from the study. Results: Out of 107 patients 56 patients had TSH below 6 mIU/L,31patients had TSH between 6mIU/L - 10 mIU/L and 13 patients had TSH more than 10 mIU/L. Seven patients dropped out from the study. There was1 miscarriage, 1 still birth from hypothyroid mother and 11 hypothyroid and subclinical hypothyroid mothers had preterm delivery. Conclusion: Prevalence of overt hypothyroidism is around 13% and subclinical hypothyroidism is around 31% in pregnant ladies in western Nepal. Also complications like stillbirth should be prevented by detecting and treating hypothyroidism early. So we recommend all patients with pregnancy to perform thyroid function test at the start of pregnancy. Nepal Journal of Medical Sciences | Volume 03 | Number 01 | January-June 2014 | Page 48-50 DOI: http://dx.doi.org/10.3126/njms.v3i1.10358

scholarly journals Evaluation of thyroid disorders in abnormal uterine bleeding

2019 ◽  
Vol 8 (6) ◽  
pp. 2236
Author(s):  
Bharat Kumar Bilwal ◽  
Apurva Garg
Keyword(s):  
Thyroid Function ◽  
Subclinical Hypothyroidism ◽  
Age Groups ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Overt Hypothyroidism ◽  
Thyroid Disorders ◽  
Hypothyroid Patient ◽  
Age Group ◽  
Menstrual Disturbances

Background: Abnormal uterine bleeding (AUB) is a common clinical presentation in gynecology. Alteration in thyroid hormones level has been associated with menstrual disturbances. This study is aimed to know the prevalence of thyroid disorders amongst AUB patients and also the different patterns of menstrual abnormalities associated with thyroid disorders.Methods: 100 Patient of clinically diagnosed AUB were taken from gynecology OPD at RNT Medical College Udaipur from October 2019 to March 2019. All the patients from 19 to 45 age groups presenting with menstrual disturbances were tested for thyroid function by measuring ST3, ST4, and S.TSH. Statistical analysis done by percentage formula.Results: Out of 100 women of AUB, majority were in the age group of 31-40 years (38%). 44% presented with menorrhagia. 65% were euthyroid, 17% had subclinical hypothyroidism, 15% had overt hypothyroidism and 3% were diagnosed as hyperthyroid. Subclinical hypothyroidism, overt hypothyroidism and hyperthyroidism were detected mostly in the age group of 31-40 years. The commonest bleeding abnormalities in hypothyroid patient were oligomenorrhoea while most of the hyperthyroid cases were having menorrhagia.Conclusions: The study concludes that biochemical evaluation of thyroid function is an easy, reliable method and should be made mandatory in all cases of AUB.

scholarly journals Status of Thyroid Disorder among the Thyroid Function Test Samples Received in a Laboratory among Postmenopausal Women: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (234) ◽  
Author(s):  
Manoranjan Shrestha ◽  
Reshmi Shrestha
Keyword(s):  
Postmenopausal Women ◽  
Thyroid Function ◽  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
Thyroid Function Test ◽  
Cross Sectional Study ◽  
Reference Laboratory ◽  
Sectional Study ◽  
Cross Sectional ◽  
Function Test

Introduction: Thyroid dysfunction prevalence is high in females worldwide which increases with age. Postmenopausal and elderly women are particularly at risk of developing comorbidities and mortality related to thyroid dysfunction. We aimed to study the prevalence of thyroid dysfunction in postmenopausal women in the National Reference Laboratory of Nepal. Methods: A descriptive cross-sectional study was conducted in National Reference Laboratory from January 2019 to June 2019 including postmenopausal females, ≥49 years. The database of thyroid function test result was used for statistical analysis and proportion of thyroid dysfunction was calculated. The data was collected after approval from the institutional review committee. Statistical Package for Social Sciences version 21 was used to study descriptive data. Results: Out of a total of 160 postmenopausal females with thyroid function tests, 71 (44.4%) had thyroid dysfunction. Subclinical hypothyroidism was the frequently occurring thyroid dysfunction 51 (32%) followed by subclinical hyperthyroidism 13 (8%), hypothyroidism 3 (2%) and hyperthyroidism 3 (2%). In our study population, thyroid dysfunction peaked at 49 to 58 years of age interval 53 (33.1%) and subclinical hypothyroidism was the most frequent form 38 (23.7%). Conclusions: Subclinical hypothyroidism was the common thyroid dysfunction in postmenopausal age which peaked at 49 to 58 years of age group. Early postmenopausal females are predisposed to increased risk of comorbidities (cardiovascular disease, osteoporosis with high fracture, depression) which could be exacerbated with thyroid dysfunction; therefore awareness of thyroid dysfunction prevalence and thyroid screening for early management seems appropriate in Nepalese postmenopausal women.

Thyroid Disease in Pregnancy

2008 ◽  
Vol 04 (01) ◽  
pp. 100
Author(s):  
N Pearce Elizabeth ◽  
M Leung Angela
Keyword(s):  
Pregnant Women ◽  
Thyroid Function ◽  
Thyroid Disease ◽  
Autoimmune Thyroid Disease ◽  
Thyroid Dysfunction ◽  
Thyroid Function Test ◽  
Autoimmune Thyroid ◽  
Thyroid Screening ◽  
Function Test ◽  
In Pregnancy

The spectrum of thyroid disease in pregnancy has implications for both the mother and the developing fetus. Here we review the interpretation of thyroid function test values, thyrotoxicosis, hypothyroidism, iodine requirements, autoimmune thyroid disease, and thyroid screening recommendations as they pertain to pregnant women. It should be noted that the management of thyroid dysfunction in pregnancy should be closely co-ordinated with obstetricians and other providers.

scholarly journals Thyroid Dysfunction and Cytological Patterns among Patients Requested for Thyroid Function Test in an Endemic Goiter Area of Gondar, North West Ethiopia

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Daniel Asmelash ◽  
Kumlgn Tesfa ◽  
Belete Biadgo
Keyword(s):  
Thyroid Function ◽  
Thyroid Dysfunction ◽  
Endemic Goiter ◽  
Wide Spectrum ◽  
Nodular Goiter ◽  
Thyroid Function Test ◽  
Subclinical Hyperthyroidism ◽  
Cross Sectional ◽  
Function Test ◽  
Study Participants

Background. Thyroid dysfunction is the most common endocrine disorder in clinical practice, and about half of the population with thyroid dysfunction remains undiagnosed. There is a fairly wide spectrum of thyroid dysfunction, which can be identified by patterns of thyroid function test results. The prevalence of thyroid dysfunction among the population varies in different studies. Methods. A cross-sectional study was conducted from February 8th to April 8th, 2017, among patients who requested for the thyroid function test in an endemic goiter area at the Gondar Hospital, University of Gondar. A pretested structured questionnaire was used to collect the data. Three milliliters of blood samples was collected in a plain test tube and centrifuged for serum separation. The thyroid function test was done by using the MINI-VIDAS automation following the manufacturer manual (Setema PLC, Italy). Data were entered and analyzed using SPSS version 20. Descriptive statistics were used for data presentation, and P value < 0.05 was considered significant. Result. Of the total 384 study participants, 346 (90.1%) were females and the study participants’ mean age was 38 ± 13.9 years. The overall thyroid dysfunction prevalence was 26.3% (101): 1.6% was identified as subclinical hypothyroidism, 0.5% hypothyroidism, 9.6% subclinical hyperthyroidism, and 14.6% hyperthyroidism, and 23.4% had goiter. Furthermore, for cytological pattern analysis, 144 study participants who fulfilled indications for fine-needle aspiration cytology (FNAC) in thyroid nodules were included. Of the total, 3 (2.1%) had thyroid carcinoma, 46 (32%) had cystic degenerated follicular cells, and 82 (57%) had nodular thyroid goiter. In addition, a clinical presentation of a total of 144 study participants, showed lymphadenites in 7 participants (4.8%), hypertension in 9 (6.2%), and cardiac failure in 12 (8.3%). Conclusion. The prevalence of thyroid dysfunction was high. The majority of thyroid dysfunction cases were newly diagnosed and more common in females. In addition, the most common disorders were subclinical hyperthyroidism and hyperthyroidism. Follicular cell with cyst degeneration and thyroid nodular goiter were the predominant FNAC findings. For early diagnosis and appropriate intervention in goiter endemic areas, the thyroid function test should be closely monitored.

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