Assessment of Septoplasty Outcome using Nasal Obstruction Symptom Evaluation Scale

Nasal obstruction, the most common presenting symptom in nasal and sinus disease, is defined as patient discomfort manifested as a sensation of insufficient airflow through the nose. Nasal septal deviation is the most common anatomical cause of nasal obstruction. Surgical correction of a deviated septum, nasal septoplasty, is the definitive treatment for septal deviation. Many studies have discussed about outcomes of septoplasty. However, there is limited published literature on nasal septoplasty and its outcome in Nepal. The aim of this study is to evaluate the outcome of septoplasty using Nasal Obstruction Symptom Evaluation (NOSE) scale, a validated outcome instrument assessing quality of life (QoL) related to nasal obstruction. A total of 52 patients aged 18 years and above, with nasal obstruction at least for 3 months, undergoing septoplasty alone were included in the study. Baseline NOSE score was calculated a week before surgery. The patients were followed up after 3 months to record postoperative NOSE score. On statistical analysis, the mean NOSE scores before and 3 months after septoplasty were 45.58±21.38 and 8.46±8.37 respectively. The mean difference was 37.11± 21.22 and p value on paired t test was less than 0.001(highly significant). The mean differences of each component of the NOSE scale questionnaire were also found to be highly significant statistically with p values less than 0.001. Gender and age did not seem to affect the outcomes. In conclusion, NOSE scale is a valid, reliable and responsive instrument that is brief and easy to complete and has potential use for outcome studies in adults with nasal obstruction. This instrument showed that septoplasty, if done in properly selected patients, results in significant improvement in nasal obstruction and disease specific quality of life with high patient satisfaction.

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Quality of life in patients with nasal obstruction after septoplasty: a single institution prospective observational study

10.21203/rs.3.rs-32150/v1 ◽

2020 ◽

Author(s):

Justyna Dabrowska-Bien ◽

Henryk Skarzynski ◽

Sebastian Filip Gorski ◽

Piotr Henryk Skarzynski

Keyword(s):

Quality Of Life ◽

Observational Study ◽

Nasal Obstruction ◽

Prospective Observational Study ◽

Common Symptom ◽

Single Institution ◽

High Satisfaction ◽

Symptom Evaluation ◽

The Mean

Abstract Background Nasal obstruction is a common symptom in otorhinolaryngological practice. It can impact significantly on the individual’s quality of life. The primary goal of the study was to evaluate quality of life after septoplasty in adults with nasal obstruction. A secondary goal was to assess the effectiveness of septoplasty. Methods This was a single institution prospective observational study. Patients had experienced septal deviation and symptomatic nasal obstruction with no benefit from medical treatment. There were 51 patients who completed the Nasal Obstruction Symptom Evaluation (NOSE-POL) scale as well as a Visual Analogue Scale (VAS) before undergoing septoplasty, 3 months later, and finally 7 months after surgery. Patients evaluated changes in their nasal obstruction and changes in their quality of life using the Clinical Global Impression Scale (CGI-S). Results There was significant improvement in nasal obstruction after septoplasty. Before septoplasty the mean score on NOSE was 60.3 ± 20.4; 3 months after surgery it was 32.9 ± 16.8; and 7 months after surgery it was 39.6 ± 33.2. VAS results also proved a significant enhancement in nasal obstruction after septoplasty. Patients reported an improvement in nasal obstruction as well as a positive change in quality of life, confirming the effectiveness of septoplasty. Conclusions In patients with deformed septum, septoplasty contributes to high satisfaction of the patient and a compelling improvement in disease-specific quality of life. The NOSE-POL questionnaire is a useful tool for measuring the outcomes of this procedure.

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Quality of Life in Patients with Nasal Obstruction after Septoplasty: A Single Institution Prospective Observational Study

International Archives of Otorhinolaryngology ◽

10.1055/s-0040-1722162 ◽

2021 ◽

Author(s):

Justyna Dąbrowska-Bień ◽

Henryk Skarżyński ◽

Sebastian Filip Górski ◽

Piotr Henryk Skarżyński

Keyword(s):

Quality Of Life ◽

Observational Study ◽

Nasal Obstruction ◽

Prospective Observational Study ◽

Common Symptom ◽

Single Institution ◽

High Satisfaction ◽

Symptom Evaluation ◽

The Individual

Abstract Introduction Nasal obstruction is a common symptom in otorhinolaryngological practice. It can impact significantly on the quality of life of the individual. Objective The primary goal of the present study was to evaluate quality of life after septoplasty in adults with nasal obstruction. A secondary goal was to assess the effectiveness of septoplasty. Methods This was a single institution prospective observational study. Patients had experienced septal deviation and symptomatic nasal obstruction with no benefit from medical treatment. There were 51 patients who completed the Nasal Obstruction Symptom Evaluation (NOSE-POL) scale as well as theVisual Analogue Scale (VAS) before undergoing septoplasty, 3 months later, and finally 7 months after surgery. Patients evaluated changes in their nasal obstruction and changes in their quality of life using the Clinical Global Impression Scale (CGI-S). Results There was a significant improvement in nasal obstruction after septoplasty. Before septoplasty, the mean score on NOSE was 60.3 ± 20.4; 3 months after surgery, it was 32.9 ± 16.8; and 7 months after surgery it was 39.6 ± 33.2. The VAS results also proved a significant enhancement in nasal obstruction after septoplasty. Patients reported an improvement in nasal obstruction as well as a positive change in quality of life, confirming the effectiveness of septoplasty. Conclusions In patients with deformed septum, septoplasty contributes to high satisfaction of the patient and a compelling improvement in disease-specific quality of life. The NOSE-POL questionnaire is a useful tool for measuring the outcomes of this procedure.

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Nasal Obstruction and Quality of Life Assessment After Septoplasty With Turbinoplasty: Correlation Between Subjective Scales

American Journal of Rhinology and Allergy ◽

10.1177/1945892420978956 ◽

2020 ◽

pp. 194589242097895

Author(s):

Gloria Corredor-Rojas ◽

María A. García-Chabur ◽

Juliana Castellanos ◽

Sergio Moreno ◽

Martin Pinzón ◽

...

Keyword(s):

Quality Of Life ◽

Nasal Obstruction ◽

Life Assessment ◽

Santa Fe ◽

Quality Of Life Assessment ◽

Symptom Evaluation ◽

Glasgow Benefit Inventory ◽

One Year ◽

The Impact

Background Assessment of nasal obstruction is imprecise due to a low correlation between findings on the physical examination and objective measures with the severity of symptoms reported by the patient even after septoplasty with turbinoplasty is performed. The aim of this study is to evaluate the use of subjective scales, and the correlation between them for the evaluation of nasal obstruction after surgery. Objective To assess the impact of undergoing septoplasty with turbinoplasty to relieve nasal obstructive symptoms and the quality of life in a mid-term period by using the Visual Analogue Scale (VAS), Nasal Obstruction Symptom Evaluation (NOSE), and Glasgow Benefit Inventory (GBI). Methods A retrospective study was conducted of patients who underwent a septoplasty with turbinoplasty due to nasal septodeviation and secondary nasal obstructive symptoms at the Hospital Universitario Fundación Santa Fe de Bogotá. Three scales were used to measure the outcomes one year after surgery: VAS (0–10), NOSE (0–100), and GBI (−100 to 100). Results Data from 56 patients (21 females, mean age 37.5 years of age, SD 12.13) was collected. The results showed that 75% of the patients had a post-surgical NOSE score below 50 and a VAS score below 6. Regarding the GBI scale, 75% of the patients improved in their quality of life. An inverse proportional correlation was found between the NOSE and GBI scales (rho = −0.3682) (95% CI −0.579 to –0.111), and there was a directly proportional correlation between the NOSE and VAS scales (rho = 0.7440) (95% CI 0.595 to 0.844). Conclusion Subjective measures suggest there was an improvement in nasal obstructive symptoms and quality of life after surgery. Non-anatomical causes such as rhinitis can be confounding factors to consider in subsequent studies. VAS stands out as a possible interchangeable scale with NOSE to measure nasal obstruction in these patients.

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The development of a financial toxicity patient-reported outcome instrument (PRO) in cancer.

Journal of Clinical Oncology ◽

10.1200/jco.2013.31.15_suppl.6612 ◽

2013 ◽

Vol 31 (15_suppl) ◽

pp. 6612-6612

Author(s):

Jonas A. De Souza ◽

Bonnie Yap ◽

Fay J. Hlubocky ◽

Mark J. Ratain ◽

David Cella ◽

...

Keyword(s):

Quality Of Life ◽

Literature Review ◽

Tumor Type ◽

Importance Score ◽

Financial Toxicity ◽

Outcome Instrument ◽

The Mean ◽

Stage 1 ◽

The Impact

6612 Background: Considering patients' (pts) subjective experience is essential for optimal decision making and care. However, despite increasing recognition of the impact of costs on oncology care, there is no accepted and validated PRO that specifically describes the financial burdens cancer pts experience. Methods: A financial toxicity PRO in advanced cancer pts undergoing treatment was developed in 3 stages. Stage 1: literature review and semi-structured qualitative interviews with pts for item generation; items were classified into 5 theoretical domains (financial, resources, affect, coping and family); draft items were examined for redundancy. Stage 2: pts assessed the items for readability and importance to their quality of life via two Likert scales (0 – 3 scales) to generate an importance score; items were ranked by decreasing importance score until at least 3 items per theoretical domain had been retained. Stage 3: pilot-testing assessing inter-item (IIC) and item–total (ITC) correlations to identify redundancy (Spearman’s rho >0.7, p<0.05) and statistically unrelated content; items were formatted in accordance with the Functional Assessment of Cancer Therapy (FACT) quality of life measure, with a 7-day time window and a 5-point Likert scale. Subject data on tumor type, age, gender, race, income, insurance type and educational level were collected. Results: 132 pts (20 in stage 1, 45 in stage 2 and 67 in stage 3) were approached and 101 agreed to participate. Stage 1: literature review, 20 pts, and 6 investigators generated 98 items, which were reduced to 58 due to redundancy. Stage 2: 35 pts ranked the items for importance, and 30 items were retained. The mean importance score was 1.83 (range 1.04 – 2.11). Stage 3: 46 pts completed the 30-item instrument. Their mean age was 61 years; 59% were male and 53% had private or employer purchased insurance; 14 items were excluded due to high IIC and 3 were excluded due to non-significant ITC, resulting in a 13-item PRO. The mean IIC and ITC of the final items were 0.373 and 0.645, respectively. Conclusions: A 13-item financial toxicity PRO has been developed in 101 pts with advanced cancers. This instrument will undergo validation as a subscale of the FACT in a larger cohort of cancer pts.

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Evaluation of Quality of Life in Terms of Sinonasal Symptoms in Children with Cystic Fibrosis

BioMolecular Concepts ◽

10.1515/bmc-2019-0011 ◽

2019 ◽

Vol 10 (1) ◽

pp. 91-98 ◽

Cited By ~ 1

Author(s):

Maryam Hassanzad ◽

Kourosh Fakhimi Derakhshan ◽

Hosseinali Ghaffaripour ◽

Ali Safavi Naeini ◽

Habib Emami ◽

...

Keyword(s):

Quality Of Life ◽

Cystic Fibrosis ◽

Chronic Rhinosinusitis ◽

Nasal Obstruction ◽

Diagnostic Study ◽

Sinus Infection ◽

Postnasal Drip ◽

Significant Difference ◽

The Mean

AbstractObjectiveSinusitis is a common complaint in children with cystic fibrosis. However, the actual prevalence of chronic rhinosinusitis and its effect on the quality of life of children have not been well considered. Therefore, the objective of this study was to determine the effect of sinonasal quality of life in children with cystic fibrosis.Materials and methodsThis study was a diagnostic study performed on 80 children with cystic fibrosis ranging from 2 to 20 years old, who were referred to the cystic fibrosis clinic of Masih Daneshvari Hospital from 2017–2018. The questionnaires used in this study were chronic rhinosinusitis screening questionnaire based on the European task force and the evaluation of the sinonasal quality of life was based on the SN-5 survey.ResultsOf the 80 patients with fibrosis from 2 to 20 years old who were recruited in the study, 41 patients were female (51.3%) and 39 were male (48.8%). In 61 cases (76.3%), there was no chronic rhinosinusitis and 19 cases (23.8%) had chronic rhinosinusitis. The mean SN-5 score in 19 patients with chronic rhinosinusitis was 3.4105 and the mean score of patients without rhinosinusitis was 1.8426, with a P-value of 0.000. The mean SN-5 score was significant between the two groups. In patients with nasal congestion, there was a significant difference in quality of life factors such as sinus infection, nasal obstruction, and allergy symptoms (P<0.001). In patients with facial pain, there was a significant difference in quality of life factors such as sinus infection, nasal obstruction, allergic symptoms, and physical activity limitation (P <0.001). There was also a significant difference in the quality of life factors such as sinus infection, nasal obstruction, and allergy symptoms in patients with postnasal drip (P <0.001).ConclusionIn children with cystic fibrosis, the quality of life of sinonasal has a significant relationship with absence of chronic rhinosinusitis. This study showed that children with chronic renosinusitis have significantly lower quality of sinonasal life than children with chronic rhinosinusitis. The results demonstrated that quality of life scores in sinus infections, nasal obstruction, and allergy symptoms were significantly higher in patients with chronic rhinosinusitis than in those without chronic rhinosinusitis. The findings of this study are important for improving children’s health related quality of life, as it leads to promoting communication between the patient and the health care provider, identifying overlooked problems, monitoring the progress of the disease and the burden of treatment, and promoting interventions in the daily life of patients.

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Evaluating the Effect of Spreader Grafting on Nasal Obstruction Using the NOSE Scale

Annals of Otology Rhinology & Laryngology ◽

10.1177/0003489416685320 ◽

2017 ◽

Vol 126 (3) ◽

pp. 219-223 ◽

Cited By ~ 6

Author(s):

Aurora G. Standlee ◽

Marc H. Hohman

Keyword(s):

Nasal Obstruction ◽

Surgical Techniques ◽

Spreader Graft ◽

Graft Placement ◽

Nose Scale ◽

Paired Samples ◽

Symptom Evaluation ◽

The Mean ◽

The Difference ◽

Mean Differences

Objective: The Nasal Obstruction Symptom Evaluation (NOSE) scale has been used to demonstrate that surgery improves nasal obstruction, but no study has directly compared surgical techniques. We performed a retrospective study comparing NOSE scores to quantify the effects of spreader grafting on postoperative nasal patency. Methods: We compared NOSE scores of patients who underwent septoturbinoplasty to open septorhinoplasty with spreader graft placement. We used a paired samples t test to evaluate the difference between pre- and postoperative NOSE scores and the improvement in NOSE score between patients who underwent septoturbinoplasty and those who underwent open septorhinoplasty with spreader graft placement. Results: Surgery reduced NOSE scores by an average of 46 points ( P < .001). The mean differences in NOSE score across all time points after septoturbinoplasty and septorhinoplasty with spreader graft placement was 40 and 49, respectively. The mean improvement in NOSE score at the second follow-up appointment was 27 for patients who had undergone septoturbinoplasty and 51 for patients who had undergone septorhinoplasty with spreader graft placement ( P = .04). Conclusion: This is the largest study quantifying the effect of spreader grafting. Greater improvement was observed from septorhinoplasty with spreader graft placement than septoturbinoplasty, and this improvement persisted over time.

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Intranasal Budesonide and Quality of Life in Pediatric Sleep-Disordered Breathing: A Randomized Controlled Trial

Otolaryngology ◽

10.1177/0194599817742597 ◽

2017 ◽

Vol 158 (4) ◽

pp. 752-759 ◽

Cited By ~ 8

Author(s):

Gunnhildur Gudnadottir ◽

Eva Ellegård ◽

Johan Hellgren

Keyword(s):

Quality Of Life ◽

Nasal Obstruction ◽

Nasal Spray ◽

Sleep Disordered Breathing ◽

Controlled Trial ◽

Analog Scale ◽

Double Blind ◽

The Mean ◽

Disordered Breathing

Objective To study the efficacy of budesonide nasal spray on the health-related quality of life and symptoms among children with sleep-disordered breathing. Study Design Randomized, parallel, double-blind, placebo-controlled trial. Setting Tertiary referral center. Subjects and Methods Sixty children (ages, 4-10 years) who were referred because of snoring and/or apneas for >3 months were included between January 2015 and June 2016 and randomized in a double-blind design to treatment with 64 μg/mL of budesonide nasal spray (n = 30) or placebo nasal spray (n = 30) twice daily for 6 weeks. The primary outcome measurement was the change in the mean OSA-18 total score from baseline. Other variables examined were individual OSA-18 domains, a visual analog scale for quality of life, symptoms (snoring, apneas, and nasal obstruction), and adenoid and tonsil size. The trial was investigator initiated and not sponsored by the pharmaceutical industry. Results Fifty-five children completed the trial. An intention-to-treat analysis revealed a significantly greater improvement in the mean OSA-18 total score after treatment with budesonide than placebo (19.5 vs 7.5, P = .0014). Intranasal budesonide also improved 2 OSA-18 domains (sleep disturbance, caregivers’ concerns), the visual analog scale score for quality of life, as well as snoring, apneas, and nasal obstruction. No serious adverse events were reported that could be linked to the treatment. Conclusion Among children with sleep-disordered breathing, 6 weeks’ treatment with intranasal budesonide significantly improved quality of life and symptoms as compared with placebo nasal spray.

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A retrospective analysis with quality of life assessment of nasal surgery for nasal obstruction

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20185292 ◽

2018 ◽

Vol 5 (1) ◽

pp. 5

Author(s):

Mehmet Fatih Karakus ◽

Suleyman Emre Karakurt ◽

Mustafa Colak

Keyword(s):

Quality Of Life ◽

Nasal Obstruction ◽

Life Assessment ◽

Rank Test ◽

Signed Rank ◽

Symptom Evaluation ◽

Signed Rank Test ◽

The Difference ◽

Age Range

Background: Nasal obstruction is a common health problem that disrupts a person’s quality of life (QoL). The Nasal Obstruction Symptom Evaluation scale (NOSE) is a QoL scale with questions specific to nasal obstruction symptoms. This study aimed to evaluate surgical success in patients who underwent nasal septal deviation surgery by using a NOSE assessment, thus determining the importance and efficacy of surgery in this group of patients.Methods: This study was conducted in between January 2016 and June 2017, including a total of 60 patients. The age range of the patients was 18–57 (mean, 34.4±9.9 years). The preoperative and postoperative scoring and surgeries were performed by the same investigator. The surgeries were septoplasty and radiofrequency applied to the inferior concha to overcome conchal hypertrophy. Preoperative mean scores were compared with postoperative second-month values. The importance of difference was evaluated with the Wilcoxon signed-rank test. Results: Preoperative minimum, maximum and mean scores were 65.0, 100.0 and 83.4 (83.41±8.15), respectively. Postoperative minimum, maximum and mean scores were 10.0, 35.0 and 21.6 (21.66±8.06), respectively. The difference in mean scores was significant (Z=−6.778; p<0.001).Conclusions: The difficulty in evaluating patient satisfaction and postoperative success stems from differences in each surgeon’s approach and the comparison of preoperative and postoperative findings. This study, which was carried out by the same researcher for all steps, differs it from similar studies.

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Role of septoplasty in allergic rhinitis

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20203570 ◽

2020 ◽

Vol 6 (9) ◽

pp. 1667

Author(s):

Hiten R. Maniyar ◽

Dharmishtha H. Parmar

Keyword(s):

Quality Of Life ◽

Allergic Rhinitis ◽

Nasal Obstruction ◽

Nasal Septum ◽

Common Symptom ◽

Age Group ◽

Control Test ◽

Deviated Nasal Septum ◽

Nose Scale

Background: It is a prospective study of 30 cases of allergic rhinitis with deviated nasal septum presented to our hospital. Analysis is done on the basis of age and sex distribution, severity of the symptoms pre and post operatively, according to nasal obstruction symptom evaluation (NOSE) scale and allergic rhinitis control test (ARCT) questionnaire which assess the quality of life.Methods: Detailed history taking and clinical examination was done. All the patients were assessed the severity of their symptoms based on a NOSE scale. An ARCT questionnaire was given to patients prior to surgery(septoplasty) and after 3 months of it.Results: In study we have observed that in the age group was 20-30years. Majority of the patients were males. The most common symptom is nasal obstruction followed by sneezing, rhinorhhea, pruritis, headache etc. The mean decrease in the NOSE score was statistically significant (before septoplasty NOSE score =14.6 and after septoplasty NOSE score=8.1). There is also improvement in quality of life which was measured by allergic rhinitis control test (ARCT) score. ARCT before septoplasty 10.2 and after 19.2.Conclusion: The study shows most common combined symptoms are nasal blockage with rhinorrhoea, more affecting the age group of 18 to 30 years, males, with deviated nasal septum towards left seen more commonly. Patients of allergic rhinitis with deviated nasal septum are benefited with septoplasty, improved symptoms like nasal obstruction and stuffiness etc. and the quality of life by decrease in the severity of allergic symptoms.

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Adaptation and validation of the Spanish version of the Nasal Obstruction Symptom Evaluation (NOSE) Scale

Rhinology Journal ◽

10.4193/rhino14.137 ◽

2015 ◽

Vol 53 (2) ◽

pp. 176-180

Author(s):

Francisco Larrosa ◽

Josep Roura ◽

Maria J. Dura ◽

Miquel Guirao ◽

Anna Alberti ◽

...

Keyword(s):

Nasal Obstruction ◽

English Language ◽

Internal Consistency Reliability ◽

Spanish Version ◽

Language Version ◽

Nose Scale ◽

Symptom Evaluation ◽

Positive Correlations ◽

Test Retest Reliability

Background: The Nasal Obstruction Symptom Evaluation (NOSE) scale is a symptom-specific, self-completed questionnaire for assessing quality of life related to nasal obstruction or its treatment in patients with septal deviation. The aim of this study was to validate the Spanish adaptation of the NOSE, thus allowing comparison across studies and international multicenter projects. Methodology: Multicenter prospective instrument validation study. Guidelines for the cross-cultural adaptation process from the original English language scale into a Spanish language version were followed. The psychometric properties (reproducibility, reliability, validity, responsiveness) of the Spanish version ("NOSE-e" for "NOSE-espanol") were assessed in 58 consecutive patients undergoing septoplasty (both before and 3 months after surgery) and 58 matched asymptomatic controls. Results: Test-retest reliability and internal consistency reliability were adequate. The NOSE-e demonstrated satisfactory construct validity. Positive correlations between the NOSE-e scores and the score of a visual analog scale measuring the subjective sensation of nasal obstruction were found. The instrument showed excellent between-groups discrimination and high response sensitivity to change. Conclusions: The Spanish version of the NOSE (NOSE-e) is a valid tool for measuring the subjective severity of nasal obstruction, and its use is recommended.

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