scholarly journals Outlook of applying of virtual reality (VR) technologies in the treatment of patients with mental disorders (review of foreign literature)

2021 ◽  
pp. 18-24
Author(s):  
V. V. Freize ◽  
L. V. Malyshko ◽  
G. I. Grachev ◽  
V. B. Dutov ◽  
N. V. Semenova ◽  
...  
Keyword(s):  
Eating Disorders ◽  
Virtual Reality ◽  
Side Effects ◽  
Mental Disorders ◽  
English Language ◽  
Obsessive Compulsive ◽  
Safe Method ◽  
Phobic Disorders ◽  
Compulsive Disorder ◽  
Russian Psychiatry

The purpose of the study was to summarize data from foreign studies about the use of virtual reality (VR) technology in the treatment of patients with various mental disorders.Materials and methods: we selected and analyzed articles from MEDLINE / PubMed databases during the period from 2000 till 2020, as well as relevant references in the bibliography of the analyzed articles. 45 articles were included in further analysis from 575 English-language articles.Results: The use of VR technologies in the treatment of mental disorders appears to be one of the promising directions in psychiatry. The successfulness of these methods in patients with eating disorders, anxiety-phobic disorders, and obsessive-compulsive disorder is supported to be evidentiary information. There is evidence of the effectiveness of such methods in patients with schizophrenia, particularly, one of the most significant results is an increase in social functioning. The absence of side effects data makes it possible to consider t VR therapy as a safe method. It is needed to make further study the areas of application of VR therapy and conduct research to identify possible side effects of this method.Conclusion: The obtained results are important for drawing attention to the prospect of using VR technologies in Russian psychiatry and demonstrate the need for further study of this method.

scholarly journals El carácter transdiagnóstico de las intrusiones mentales: una revisión y una propuesta basada en datos.

2018 ◽  
Vol 23 (2) ◽  
pp. 135 ◽  
Author(s):  
Belén Pascual-Vera ◽  
Amparo Belloch
Keyword(s):  
Eating Disorders ◽  
Mental Disorders ◽  
Obsessive Compulsive Disorder ◽  
Body Dysmorphic Disorder ◽  
Common Symptom ◽  
Obsessive Compulsive ◽  
Symptom Dimensions ◽  
Compulsive Disorder ◽  
Functional Consequences ◽  
Intrusive Cognitions

Abstract: The transdiagnostic nature of mental intrusions: A review and data-based proposal. The objective of a transdiagnostic perspective in psychopathology is to better understand the commonalities among clinically different mental disorders on the basis of a set of shared etiopathogenic dimensions and processes. Unwanted intrusive cognitions (UI) and their functional consequences had been proposed as symptom dimensions in Obsessive-Compulsive Disorder (OCD), Body Dysmorphic Disorder (BDD), Hypochondriasis (HYP) and Eating Disorders (EDs). In this article, we review the empirical data about the putative transdiagnostic nature of UI and their functional consequences in the four mentioned disorders. Firstly, the results about the universality and dimensionality of UI with contents of each disorder are reviewed. Secondly, data about UI as common symptom dimensions in OCD and EDs are presented. Finally, we offer information about our current research about the hypothetical transdiagnostic nature of UI with obsessional, dysmorphic, hypochondriac, and eating-disorders contents. Keywords: Mental intrusions; transdiagnostic; obsessive-compulsive disorder; body dysmorphic disorder; hypochondriasis; eating disorders.Resumen: El propósito de adoptar un enfoque transdiagnóstico en psicopatología es comprender las comunalidades entre trastornos mentales clínicamente diferentes sobre la base de un rango de dimensiones y procesos etiopatogénicos compartidos. Las intrusiones mentales no deseadas (IM) y sus consecuencias funcionales se han propuesto como dimensiones de síntomas en el Trastorno Obsesivo-Compulsivo (TOC), el Trastorno Dismórfico Corporal (TDC), la Hipocondría (HIP) y los Trastornos Alimentarios (TA). Este artículo resume y actualiza los datos disponibles sobre el potencial valor transdiagnóstico de las intrusiones mentales y sus consecuencias funcionales en los cuatro trastornos mencionados. Se presentan, primero, los resultados sobre la universalidad y dimensionalidad de IM con contenidos característicos de cada trastorno; segundo, los datos sobre las IM como dimensiones de síntomas comunes en el TOC y los TA; por último, se aporta información sobre una investigación propia cuyo objetivo es poner a prueba la hipótesis del carácter transdiagnóstico de IM obsesivas, dismórficas, hipocondríacas y alimentarias. 

scholarly journals Break in volition: a virtual reality study in patients with obsessive-compulsive disorder

2013 ◽  
Vol 229 (3) ◽  
pp. 443-449 ◽  
Author(s):  
Pietro Cipresso ◽  
Filippo La Paglia ◽  
Caterina La Cascia ◽  
Giuseppe Riva ◽  
Giovanni Albani ◽  
...  
Keyword(s):  
Virtual Reality ◽  
Obsessive Compulsive Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

The Antidepressant Effects of 5-HT Uptake Inhibitors

1989 ◽  
Vol 155 (S8) ◽  
pp. 32-40 ◽  
Author(s):  
Anna Åberg-Wistedt
Keyword(s):  
Side Effects ◽  
Clinical Studies ◽  
Human Platelets ◽  
Obsessive Compulsive ◽  
Functional Roles ◽  
Compulsive Disorder ◽  
Uptake Inhibitors ◽  
Antidepressant Effects ◽  
5 Ht Uptake ◽  
Review Reports

The functional roles of monaminergic transmitters in depression have been widely studied during the past decade. Data from that research suggest that lower levels of the 5-HT metabolite, 5-HIAA, in the cerebrospinal fluid; 5-HT uptake in human platelets; and platelets [3H]-imipramine binding sites occur in depressed patients. In recent years several potent and selective 5-HT uptake inhibitors have become available for clinical studies. The first shown to have antidepressant effects, zimelidine, was followed by similar compounds such as femoxetine, fluvoxamine, Citalopram, indalpine, fluoxetine, paroxetine, and sertraline. The effectiveness of serotonin inhibitors in treating other disorders, such as obsessive–compulsive disorder, anxiety, and panic disorder, has also been demonstrated. This review reports the data from clinical studies with these agents. The 5-HT uptake inhibitors are devoid of anticholinergic properties and have not produced weight gain or sedative side-effects, but may have another profile of side-effects. Headache, nausea, and vomiting have been reported, however.

scholarly journals Predicting Eating Disorder and Anxiety Symptoms Using Anorexia Nervosa and Obsessive-Compulsive Disorder Polygenic Scores

2020 ◽  
Author(s):  
Zeynep Yilmaz ◽  
Katherine Schaumberg ◽  
Matt Halvorsen ◽  
Erica L. Goodman ◽  
Leigh C. Brosof ◽  
...  
Keyword(s):  
Eating Disorders ◽  
Sex Differences ◽  
Anorexia Nervosa ◽  
Eating Disorder ◽  
Obsessive Compulsive Disorder ◽  
Genetic Risk ◽  
Anxiety Symptoms ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Polygenic Scores

Clinical, epidemiological, and genetic findings support an overlap between eating disorders, obsessive-compulsive disorder (OCD), and anxiety symptoms. However, little research has examined the role of genetic factors in the expression of eating disorders and OCD/anxiety phenotypes. We examined whether the anorexia nervosa (AN), OCD, or AN/OCD transdiagnostic polygenic scores (PGS) predict eating disorders, OCD, and anxiety symptoms in a large population-based developmental cohort. Using summary statistics files from the Psychiatric Genomics Consortium Freeze 2 AN and Freeze 1 OCD GWAS, we first conducted an AN/OCD transdiagnostic GWAS meta-analysis and then calculated PGS for AN, OCD, and AN/OCD in participants from the Avon Longitudinal Study of Parents and Children with available genetic and phenotype data on eating disorder, OCD, and anxiety diagnoses and symptoms (sample size 3,212-5,369 per phenotype). We observed sex differences in the PGS prediction of eating disorder, OCD, and anxiety-related phenotypes, with AN genetic risk manifesting at an earlier age and playing a more prominent role in eating disorder phenotypes in boys than in girls. Compulsive exercise was the only phenotype predicted by all three PGS (e.g., PAN(boys)=0.0141 at age 14; POCD(girls)=0.0070 at age 16; PAN/OCD(all)=0.0297 at age 14). Our results suggest that earlier detection of eating disorder, OCD, and anxiety-related symptoms could be made possible by including measurement of genetic risk for these psychiatric conditions while being mindful of sex differences.

scholarly journals How New Technologies Can Improve Prediction, Assessment, and Intervention in Obsessive-Compulsive Disorder (e-OCD): Review

10.2196/11643 ◽  
2019 ◽  
Vol 6 (12) ◽  
pp. e11643 ◽  
Author(s):  
Florian Ferreri ◽  
Alexis Bourla ◽  
Charles-Siegfried Peretti ◽  
Tomoyuki Segawa ◽  
Nemat Jaafari ◽  
...  
Keyword(s):  
Machine Learning ◽  
Virtual Reality ◽  
Obsessive Compulsive Disorder ◽  
New Technologies ◽  
Assessment Tools ◽  
Clinical Practices ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Pubmed Database ◽  
The Impact

Background New technologies are set to profoundly change the way we understand and manage psychiatric disorders, including obsessive-compulsive disorder (OCD). Developments in imaging and biomarkers, along with medical informatics, may well allow for better assessments and interventions in the future. Recent advances in the concept of digital phenotype, which involves using computerized measurement tools to capture the characteristics of a given psychiatric disorder, is one paradigmatic example. Objective The impact of new technologies on health professionals’ practice in OCD care remains to be determined. Recent developments could disrupt not just their clinical practices, but also their beliefs, ethics, and representations, even going so far as to question their professional culture. This study aimed to conduct an extensive review of new technologies in OCD. Methods We conducted the review by looking for titles in the PubMed database up to December 2017 that contained the following terms: [Obsessive] AND [Smartphone] OR [phone] OR [Internet] OR [Device] OR [Wearable] OR [Mobile] OR [Machine learning] OR [Artificial] OR [Biofeedback] OR [Neurofeedback] OR [Momentary] OR [Computerized] OR [Heart rate variability] OR [actigraphy] OR [actimetry] OR [digital] OR [virtual reality] OR [Tele] OR [video]. Results We analyzed 364 articles, of which 62 were included. Our review was divided into 3 parts: prediction, assessment (including diagnosis, screening, and monitoring), and intervention. Conclusions The review showed that the place of connected objects, machine learning, and remote monitoring has yet to be defined in OCD. Smartphone assessment apps and the Web Screening Questionnaire demonstrated good sensitivity and adequate specificity for detecting OCD symptoms when compared with a full-length structured clinical interview. The ecological momentary assessment procedure may also represent a worthy addition to the current suite of assessment tools. In the field of intervention, CBT supported by smartphone, internet, or computer may not be more effective than that delivered by a qualified practitioner, but it is easy to use, well accepted by patients, reproducible, and cost-effective. Finally, new technologies are enabling the development of new therapies, including biofeedback and virtual reality, which focus on the learning of coping skills. For them to be used, these tools must be properly explained and tailored to individual physician and patient profiles.

Neurostimulation therapies

2020 ◽  
pp. 217-232
Author(s):  
Daniel W. O’Connor ◽  
Christos Plakiotis ◽  
Peter Farnbach
Keyword(s):  
Cognitive Impairment ◽  
Deep Brain Stimulation ◽  
Transcranial Magnetic Stimulation ◽  
Side Effects ◽  
Magnetic Stimulation ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Treatment Of Depression ◽  
Electrical Impulses ◽  
The Brain

Electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS) and deep brain stimulation (DBS) all entail the delivery of electrical impulses to the brain with the aim of relieving mental disorders. ECT is an effective treatment of depression, mania and catatonia and, to a lesser extent, of schizophrenia. Its side effects, principally cognitive impairment, are mitigated through the use of individually tailored, unilateral delivery. TMS is more convenient but of lesser effectiveness. DBS, while reversible and thus safer than lesional surgery, is a major undertaking that is reserved at present for profoundly disabling depression, obsessive-compulsive disorder (OCD), and Tourette’s syndrome.

Pharmacotherapy of anxiety and related disorders

2020 ◽  
pp. 147-164
Author(s):  
Dan J. Stein
Keyword(s):  
Clinical Trials ◽  
Anxiety Disorder ◽  
Mental Disorders ◽  
Randomized Clinical Trials ◽  
Generalized Anxiety ◽  
Obsessive Compulsive ◽  
Future Directions ◽  
Compulsive Disorder ◽  
Translational Models ◽  
Shed Light

Anxiety disorders are the most prevalent of the mental disorders, and good translational models of these conditions encourage pharmacotherapy studies. This chapter discusses six randomized clinical trials that have contributed significantly to the pharmacotherapy of anxiety and related disorders, including generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, and social anxiety disorder. Although any such list is necessarily incomplete, these selections may shed light on early and ongoing challenges in the field and on key advances to date. After reviewing these foundational papers, the advances they represent, and the work that they have given impetus to, the chapter closes by considering future directions in work on the pharmacotherapy of anxiety and related disorders.

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