scholarly journals The antidepressants effects on microbiota: unobvious possibilities Research article

2021 ◽  
Vol 57 (4) ◽  
pp. 8-14
Author(s):  
G. V. Rukavishnikov ◽  
L. V. Leonova ◽  
E. D. Kasyanov ◽  
N. G. Neznanov ◽  
G. E. Mazo
Keyword(s):  
Therapeutic Process ◽  
Clinical Importance ◽  
Chronic Administration ◽  
Therapeutic Effects ◽  
Negative Effects ◽  
Research Article ◽  
Promising Area ◽  
Future Drug ◽  
Different Strains

Despite the emergence of new antidepressants with different mechanisms of action, a large number of problems in antidepressant therapy remain. Considering the known antimicrobial activity of antidepressants, the role of the microbiota in the thymoanaleptic activity of these drugs is of high interest. In recent years, important data have been obtained on the role of the gut microbiota in the regulation of behavior and the pathophysiology of a number of mental disorders, including depression. Of particular interest is the assessment of the normal intestinal microbiota role in the course of the therapeutic process. The emerging bi-directional interactions between drugs and microorganisms may be critical for personalized drug selection and future drug development. However, at the present time, this problem remains poorly understood. The proposed manuscript articulates the main directions that are of clinical importance and can become an object for further study in this area.The research results indicate that the effect of antidepressants on the microbiota is a promising area, the study of which could provide many important findings for clinical practice. This type of therapeutic manipulation can provide an opportunity for intervention in order to potentiate the activity of antidepressants or to minimize side effects. The problem with this method of intervention is enormous complexity, when manipulations can have both positive and negative effects simultaneously, depending on different strains of microorganisms influencing different therapeutic effects. More research is needed to understand what changes occur in the microbiome with acute and chronic administration of specific antidepressants. Perhaps this will contribute to the development of microbiomodulatory tactics for individualized interventions.

The role of patients education in the hygiene of removable dentures – a case report

2018 ◽  
Vol 68 (1) ◽  
pp. 95-100
Author(s):  
Bogna Scheffs ◽  
Agnieszka Marcinkowska
Keyword(s):  
Oral Hygiene ◽  
Bacterial Infections ◽  
Negative Influence ◽  
Therapeutic Effects ◽  
Prosthetic Rehabilitation ◽  
Negative Effects ◽  
Microbial Infections ◽  
Removable Prosthesis

Prosthetic treatment with removable dentures is long- lasting process, which requires from patients motivation and awareness about oral hygiene and proper maintantenance of dental prosthesis. Removable prosthesis wearers are much more susceptible to fungal and bacterial infections than people who do not use any dentures. Knowledge of negative influence of dental plaque, denture plaque and intraoral infections on oral and whole organism health is essential. Forcing patients, the role of oral hygiene and the need for follow- up care is an integral part of the treatment. Realization of this conditions enable specialists to get positive therapeutic effects. In addition, availability of numerous hygiene products provides effective protection against the negative effects of microbial infections. This paper presents cases of prosthetic rehabilitation of patients with unsatisfactory hygiene of removable prosthetic appliances. New dentures were prepared and focused on thorough education about appropriate handling and good oral hygiene maintenance. Improved hygiene and patients’ health awareness were observed.

scholarly journals Body Rhetorics and Kinesthetic Empathy in the Video Game Bound (2016)

Res Rhetorica ◽  
2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Agata Waszkiewicz
Keyword(s):  
Video Game ◽  
Therapeutic Process ◽  
Game Studies ◽  
American Dance Therapy Association ◽  
Therapeutic Effects ◽  
Dance Movement ◽  
Western Psychology ◽  
Visual Rhetorics ◽  
Kinesthetic Empathy

Dance is found in every known human culture as part of religious, social and healing ceremonies. The increased interest in the role of dance in western psychology corresponds with the creation of the American Dance Therapy Association (ADTA) founded by Marian Chace, and the beginning of the dance movement therapy (DMT). The Association introduced the dance and the dance-based movement as part of the therapeutic process, in order to explore the relationship between the expression of individual emotions and movement. Drawing both from the visual rhetorics approach (Patterson and Corning 1997) and the game studies (Fernández-Vara 2009) I will analyze the multiple narrative layers in the Bound video game (2016), pointing to the mutual relationship the player and the game have on each other (Keogh 2018) decoding the game as a metaphor for the therapeutic effects of dance.

Can trust become a factor of economic growth? Dynamic changes in the level of trust of Russian youth

2020 ◽  
pp. 92-107 ◽  
Author(s):  
A. I. Bakhtigaraeva ◽  
A. A. Stavinskaya
Keyword(s):  
Institutional Environment ◽  
Negative Effects ◽  
Dynamic Changes ◽  
Generalized Trust ◽  
Level Of Education ◽  
Advantages And Disadvantages ◽  
The Future ◽  
Analysis Of Dynamics

The article considers the role of trust in the economy, the mechanisms of its accumulation and the possibility of using it as one of the growth factors in the future. The advantages and disadvantages of measuring the level of generalized trust using two alternative questions — about trusting people in general and trusting strangers — are analyzed. The results of the analysis of dynamics of the level of generalized trust among Russian youth, obtained within the study of the Institute for National Projects in 10 regions of Russia, are presented. It is shown that there are no significant changes in trust in people in general during the study at university. At the same time, the level of trust in strangers falls, which can negatively affect the level of trust in the country as a whole, and as a result have negative effects on the development of the economy in the future. Possible causes of the observed trends and the role of universities are discussed. Also the question about the connection between the level of education and generalized trust in countries with different quality of the institutional environment is raised.

Role of Self Help Groups A Study with Specific Reference to Vellore District

GIS Business ◽  
2019 ◽  
Vol 14 (6) ◽  
pp. 243-252
Author(s):  
Dr. M.A. Bilal Ahmed ◽  
Dr. S. Thameemul Ansari
Keyword(s):  
Leadership Role ◽  
Three Dimensions ◽  
Specific Reference ◽  
Government Organizations ◽  
Research Article ◽  
Self Help ◽  
The People ◽  
The World ◽  
Self Help Groups

SHG is a movement which came to being in the early 1969. Prof. Muhammed Younus, a great economist of Bangladesh took initiative in setting up Self Help Groups and these SHGs were gradually spread all over the world. This social movement unites the people hailing from poor background. Those who are joining this group feel socially and economically responsible to one another. In India, there are some likeminded bodies and stakeholders of some government organizations play pivotal role towards the formation of SHG In this research article, role of SHGs in Vellore district is studies under the three dimensions of Cognitive role, leadership role and role towards entrepreneurship.

الإمام المصلح عبد الحميد بن باديس: حياته وجهوده التربوية Reformer Imam Abdal-hamid ibn Badis: His Life and Educational Reforms

2015 ◽  
Vol 12 (1) ◽  
pp. 105-152
Author(s):  
باي زكوب عبد العالي ◽  
سوهيرين محمد صوليحين
Keyword(s):  
Twentieth Century ◽  
Educational Reforms ◽  
Daily Routine ◽  
Journalism Education ◽  
Negative Effects ◽  
Educational Approach ◽  
Political Economic ◽  
Difficult Times

الملخّصيعدّ عبد الحميد بن باديس أحد العلماء الجزائريين المبرزين بالإصلاح الاجتماعي والدّيني والسّياسي والتربوي، عاش خمسين سنة في القرن العشرين الميلادي، حيث كانت ولادته سنة 1889م، وكانت وفاته سنة 1940م، ولقد فرض الواقع الجزائري إبّان فترة الاحتلال الفرنسي الذي كان يسعى إلى طمس ثوابت الأمّة الجزائرية، وخرق تاريخها، وهُويّتها، وثقافتها، ووحدتها الدينيّة، واللّغوية على ابن باديس أن يسلك نهج التربية والتعليم، قاصداً بذلك مواجهة الاحتلال الفرنسي الغاشم من خلال عدّة جبهات ومجالات كمثل مجال الصحافة، ومجال التربية والتعليم، ومجال الجمعيات، ومجال السياسة وغير ذلك، يهدف هذا البحث إلى إبراز دور عبد الحميد بن باديس في النّهوض بالأمّة الجزائريّة نحو تربيّة أفضل، وحياة أسعد، فيبدأ أوّلاً وبشكل موجز، بالتعرّف على الفترة الصعبة التي عايشها ابن باديس والمتمثلة في فترة الاحتلال الفرنسي الغاشم، وآثاره السلبية على الصعيد السياسي والاقتصادي والاجتماعي والثقافي والديني الجزائري وقتذاك، ثم يقوم ثانياً بتسليط الضّوء على حياة ابن باديس وتكوينه العلمي ورحلاته الداخلية وأسفاره الخارجية؛ ثم يسعى ثالثاً وبتعمّق، التعرّف على أعمال ابن باديس الاجتماعيّة وجهوده التربويّة التي أخذت حظّاً وافراً من حياته اليومية، والتي تركّزت على منبرين رئيسين، هما: منبر الصّحافة، ومنبر التربيّة والتعليم.الكلمات المفتاحيّة: الإمام عبد الحميد بن باديس، الاحتلال الفرنسي، التربية، الجزائر، الإصلاح.             AbstractImÉm ‘Abd al-×amÊd ibn BÉdÊs is an Algerian scientist, and eminent social, religious, political and educational reformer. He lived fifty years in the twentieth century. He was born in 1889 and died in 1940, and lived during the French occupation that attempted to distort and undermine the foundations of the Algerian nation by destroying its history, identity, culture, and religious and linguistic unity. Ibn BÉdÊs pursued an educational approach to face the brutal French occupation on several fronts, including journalism, education, civil associations, politics, etc. This paper highlights the role of ‘Abd al-×amÊd ibn BÉdÊs in the advancement of the Algerian nation toward better education and a happier life. The paper begins with a brief canvas of the difficult times in which Ibn BÉdÊs lived, and the negative effects of the brutal French occupation from political, economic, social, cultural and religious angles, besides highlighting the life of Ibn BÉdÊs, his education and his local and international travels. The focus of this research is an in-depth examination of Ibn BÉdÊs’ social and educational efforts that consumed much of his daily routine: journalism, and education.Keywords: ImÉm ‘Abd al-×amÊd ibn BÉdÊs, the French Occupation, Education, Algeria, Reform.

Monitoring the marine environment for small round structured viruses (SRSVS): a new approach to combating the transmission of these viruses by molluscan shellfish

1998 ◽  
Vol 38 (12) ◽  
pp. 51-56 ◽  
Author(s):  
K. Henshilwood ◽  
J. Green ◽  
D. N. Lees
Keyword(s):  
Enteric Virus ◽  
Winter Period ◽  
Rt Pcr ◽  
Cloning And Sequencing ◽  
New Approach ◽  
Human Enteric Virus ◽  
Different Strains ◽  
The Uk ◽  
Public Health Protection

This study investigates human enteric virus contamination of a shellfish harvesting area. Samples were analysed over a 14-month period for Small Round Structured Viruses (SRSVs) using a previously developed nested RT-PCR. A clear seasonal difference was observed with the largest numbers of positive samples obtained during the winter period (October to March). This data concurs with the known winter association of gastroenteric illness due to oyster consumption in the UK and also with the majority of the outbreaks associated with shellfish harvested from this area during the study period. RT-PCR positive amplicons were further characterised by cloning and sequencing. Sequence analysis of the positive samples identified eleven SRSV strains, of both Genogroup I and Genogroup II, occurring throughout the study period. Many shellfish samples contained a mixture of strains with a few samples containing up to three different strains with both Genogroups represented. The observed common occurrence of strain mixtures may have implications for the role of shellfish as a vector for dissemination of SRSV strains. These results show that nested RT-PCR can identify SRSV contamination in shellfish harvesting areas. Virus monitoring of shellfish harvesting areas by specialist laboratories using RT-PCR is a possible approach to combating the transmission of SRSVs by molluscan shellfish and could potentially offer significantly enhanced levels of public health protection.

scholarly journals Robots as intelligent assistants to face COVID-19 pandemic

2020 ◽  
Author(s):  
Valeria Seidita ◽  
Francesco Lanza ◽  
Arianna Pipitone ◽  
Antonio Chella
Keyword(s):  
Technological Progress ◽  
World Economy ◽  
The State ◽  
Research Groups ◽  
Negative Effects ◽  
The World ◽  
Intelligent Assistants

Abstract Motivation The epidemic at the beginning of this year, due to a new virus in the coronavirus family, is causing many deaths and is bringing the world economy to its knees. Moreover, situations of this kind are historically cyclical. The symptoms and treatment of infected patients are, for better or worse even for new viruses, always the same: more or less severe flu symptoms, isolation and full hygiene. By now man has learned how to manage epidemic situations, but deaths and negative effects continue to occur. What about technology? What effect has the actual technological progress we have achieved? In this review, we wonder about the role of robotics in the fight against COVID. It presents the analysis of scientific articles, industrial initiatives and project calls for applications from March to now highlighting how much robotics was ready to face this situation, what is expected from robots and what remains to do. Results The analysis was made by focusing on what research groups offer as a means of support for therapies and prevention actions. We then reported some remarks on what we think is the state of maturity of robotics in dealing with situations like COVID-19.

Open-mindedness as a Corrective Virtue

Philosophy ◽  
2020 ◽  
Vol 96 (1) ◽  
pp. 73-97
Author(s):  
Hassan Alsharif ◽  
John Symons
Keyword(s):  
Recent Literature ◽  
Confirmation Bias ◽  
Negative Effects ◽  
Shed Light

AbstractThis paper argues that open-mindedness is a corrective virtue. It serves as a corrective to the epistemic vice of confirmation bias. Specifically, open-mindedness is the epistemically virtuous disposition to resist the negative effects of confirmation bias on our ability to reason well and to evaluate evidence and arguments. As part of the defense and presentation of our account, we explore four discussions of open-mindedness in the recent literature. All four approaches have strengths and shed light on aspects of the virtue of open-mindedness. Each mentions various symptoms of confirmation bias and some explore aspects of the corrective role of open-mindedness. However, ours is the first to explicitly identify open-mindedness as a corrective virtue to the specific epistemic vice of confirmation bias. We show how the corrective account also permits a response to the concern that open-mindedness might not actually count as a virtue.

scholarly journals Therapeutic Role of Tocilizumab in SARS-CoV-2-Induced Cytokine Storm: Rationale and Current Evidence

2021 ◽  
Vol 22 (6) ◽  
pp. 3059
Author(s):  
Corrado Pelaia ◽  
Cecilia Calabrese ◽  
Eugenio Garofalo ◽  
Andrea Bruni ◽  
Alessandro Vatrella ◽  
...  
Keyword(s):  
Review Article ◽  
Lung Damage ◽  
Current Evidence ◽  
Therapeutic Effects ◽  
Cytokine Storm ◽  
Future Perspectives ◽  
Pathogenic Role ◽  
Refractory Rheumatoid Arthritis ◽  
Life Threatening

Among patients suffering from coronavirus disease 2019 (COVID-19) syndrome, one of the worst possible scenarios is represented by the critical lung damage caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-induced cytokine storm, responsible for a potentially very dangerous hyperinflammatory condition. Within such a context, interleukin-6 (IL-6) plays a key pathogenic role, thus being a suitable therapeutic target. Indeed, the IL-6-receptor antagonist tocilizumab, already approved for treatment of refractory rheumatoid arthritis, is often used to treat patients with severe COVID-19 symptoms and lung involvement. Therefore, the aim of this review article is to focus on the rationale of tocilizumab utilization in the SARS-CoV-2-triggered cytokine storm, as well as to discuss current evidence and future perspectives, especially with regard to ongoing trials referring to the evaluation of tocilizumab’s therapeutic effects in patients with life-threatening SARS-CoV-2 infection.

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