scholarly journals The efficacy of the use of vaginal suppositories API-NORM® in patients after surgical treatment of cervical ectopy associated with HPV

2019 ◽  
Vol 23 (3) ◽  
pp. 410-413
Author(s):  
H. Chaika ◽  
O. Kucherenko ◽  
L. Strichenko

The aim of the study is to improve the effectiveness of rehabilitation measures after surgical treatment of ectopic cylindrical cervical epithelium in women of reproductive age associated with HPV. In order to increase the effectiveness of rehabilitation measures after surgical treatment, 70 women of reproductive age with an ectopia of the cylindrical epithelium of the cervix associated with HPV were examined. According to rehabilitation measures after surgical treatment, they were divided into two groups. The main group included 52 women who, after surgical treatment for rehabilitation, received vaginal suppositories containing activated propolis extract, beeswax, St. John's wort extract, marigold and sea buckthorn oil (API-NORM), once a day for 10 days. The comparison group included 28 women treated with suppositories containing 500 mg of methyluracil. Analysis of the data obtained was carried out using the program “STATISTICA 5.5” (owned by the Central Scientific Research Institute of National Pirogov Memorial Medical University, Vinnytsya, license No.AXXR910A374605FA) using non-parametric methods for assessing the results. It was determined that the use of this method of rehabilitation after electroexcision treatment of cervical pathology made it possible to reduce the period of regeneration of the wound surface by 2.4 times and reduce the bleeding rate to 1.9% in the postoperative period. The appointment of API-NORM vaginal suppositories for the purpose of postoperative rehabilitation helps to reduce the recurrence rate of the disease and coagulated cervical syndrome to 3.8% and 1.9%, respectively, and gives us the full cervical epithelization in 94.2% of cases. This proves the high efficiency of the proposed method of rehabilitation.

2017 ◽  
Vol 176 (3) ◽  
pp. 56-60
Author(s):  
V. G. Pishchik ◽  
A. D. Obornev ◽  
M. A. Atyukov ◽  
A. S. Petrov ◽  
A. I. Kovalenko

OBJECTIVE. The article analyzed the experience of treatment of endometriosis-related pneumothorax (ERP). MATERIAL AND METHODS. The diagnosis of ERP was detected in 30 women at the period from 2004 to 2015. A control group consisted of 149 women. RESULTS. Statistically significant differences associated with presence of ERP were the elder age, right-side localization and recurrence course of disease. Diaphragmatic fenestrations and endometriotic ectopy and their combinations were specific findings in ERP-group. This group of patients characterized by frequent recurrences and higher rate of complications. The most effective method of treatment of ERP was diaphragm resection with pleurectomy and hormone therapy from 3 to 6 months after surgery. CONCLUSIONS. Endometriosis-related pneumothorax could cause up to 34 % cases of spontaneous pneumothorax in women of reproductive age. Diaphragmatic fenestrations and endometriotic lesions were specific signs of EAP. Direct visual examination of the pleural cavity was inevitable for reliable diagnostics of the disease. Surgical treatment of ERP was determined by higher rates of complication and recurrence. Postoperative hormone therapy could significantly improve the results of surgical treatment of ERP.


2006 ◽  
Vol 13 (02) ◽  
pp. 186-191
Author(s):  
SHAHID IRSHAD RAO ◽  
HINA KOKAB ◽  
RASHIDA SADIQ

Introduction: Poly Cystic Ovarian Disease (PCOD) is probably one of the most commonendocrinological disorders amongst the women during their reproductive years. Using USG criteria only 20-33% ofapparently healthy women in childbearing period, have been found to have PCOD in population study. Whereasprevalence of 4-10% in women of reproductive age is commonly reported when the diagnosis is based on clinical,biochemical and US scan features. Objective:-Diagnosis and management of polycystic ovarian disease. Setting SeyalMedical Centre, Multan. Duration From January 2002 to December 2003. Material and Methods: Sample size: 200patients. Results: Most of he patients were in the age group of 21-30 years. The youngest patient was of 17 years andeldest was of 42 years. Majority of the women were nulliparous or of low parity comprising 92% of cases. Thecommonest symptom was menstrual disorder in 168 Patients (84%). Ultrasound is very helpful for diagnosis of POD.About 80% of patients were diagnosed as PCOD on ultrasound. There is increased level of LH in 72% patients, 8%have raised prolactin levels. All patients were first treated with clomiphene citrate while surgical treatment is done inonly 30% of cases. GnRH analogue and purified FSH were not used because they are quite expensive. Conclusion:PCOD is found to be one of the commonest problem in reproductive years of life. Clomiphene citrate is first linetreatment in PCOD for infertility. Laparoscopic drilling has very good results especially in clomiphene resistant cases.


ScienceRise ◽  
2021 ◽  
pp. 55-61
Author(s):  
Serhii Vdovichenko ◽  
Anna Bober ◽  
Oleksandra Lubkovska ◽  
Vitalii Strakhovetskyi

The object of the study: Uterine fibroids (UF) in women of early reproductive age. The problem to be solved: Improving the effectiveness of postoperative rehabilitation in women of early reproductive age with uterine fibroids based on the study of its morphological features and improvement of rehabilitation measures. The main scientific results: It was found that in women of early reproductive age with UF the most common complaints are posthemorrhagic anemia (61.0 %, or 61 women). Regarding the menstrual cycle, the most common dysmenorrhea – 26.0 % (in 26 women). The importance of heredity in the development of such pathology in young women (32.0 %, or 32 women) was confirmed. The most common localization of fibroids is interstitial – 79.0 % (in 79 women). Morphological study found that women of early reproductive age most often have a simple UF, namely 96 % (96 women). Uterine leiomyoma was present in 56 % (56 women). A study of the hormonal status of women of early reproductive age found that the mean values ​​of hormones such as follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol, progesterone, prolactin and testosterone were higher before surgery than after. When comparing rehabilitation methods (combined oral contraceptives (COCs) or gonadotropin-releasing hormone agonists (GnRH agonists), it was found that postoperative rehabilitation by using COCs for 6-12 months provides significantly better indicators of recovery of hormonal status, indicating the effectiveness of rehabilitation method. Scope of practical application of research results: Practical medicine specializing in the diagnosis, treatment and prevention of recurrence of uterine fibroids. Innovative technological product: Improved algorithm of postoperative rehabilitation measures by applying COC for 6-12 months after myomectomy, which provides significantly better results in restoring hormonal status during rehabilitation. Scope of application of innovative technological product: clinical medical practice related to the diagnosis, treatment and prevention of recurrence of uterine fibroids.


2006 ◽  
Vol 12 (1) ◽  
pp. 28-33 ◽  
Author(s):  
Christine Bain

Endometriosis is an estrogen-dependent condition that primarily inflicts women of reproductive age. There are several gradations of the disease and its extent does not always signify its symptomatic presentation. In those women who have long suffered from endometriosis, previous treatments and their assumed success influence clinical decision making on the use of hormone replacement therapy after menopause. This review considers the management strategies for those women who have become prematurely menopausal after extensive surgical treatment for endometriosis.


2020 ◽  
Vol 9 (4) ◽  
pp. 1494-1501

Despite the emergence of new directions in the treatment of patients with hyperplastic processes of the endometrium, the problems of treatment of this pathology remain one of the most pressing issues in gynecology and still not the final solution. Therefore, the aim of our study was to test the effectiveness of antiviral therapy as an antirelapse treatment of hyperplastic processes of the endometrium (HPE) in women of reproductive age. Patients with hyperplastic processes of the endometrium (60) who sought medical help in the gynecological department were examined and treated depending on the method of treatment after the data were obtained through morphological examination. The obtained data demonstrate a fairly high efficiency of the selected treatment and diagnostic algorithm. The recurrence rate of acyclovir in women with HPE is -16.67%, which is significantly (p <0.05) lower than in women who received traditional therapy - 40%. Additional use of antiviral therapy in the complex treatment of GPP prevents recurrence of the disease and significantly increases treatment by 2.40 times. The results of the study substantiate the need to include antiviral therapy as a pathogenetically justified therapy for patients with hyperplastic endometrial processes.


2019 ◽  
Vol 3 (Issue 4) ◽  
Author(s):  
Arystanbek O. Atykanov ◽  
Nurgazy T. Dzhanuzakov

This paper presents data on the effect of unilateral and bilateral electrical stimulation of the ovaries in 36 women of reproductive age with polycystic ovary syndrome and infertility on follicular reserve, estimated by the concentration of anti-Mullerian hormone in the blood serum. The results of surgical treatment showed that in the postoperative period in women, both with unilateral and bilateral ovarian cauterization, it does not lead to a critical decrease in the follicular reserve compared with indicators of healthy women. 


2020 ◽  
Vol 5 ◽  
pp. 29-32
Author(s):  
O. M. Proshchenko

The article presents an assessment and analysis of the most important medical and social risk factors for long-term postoperative urogenital disorders in women of reproductive age after radical surgical treatment for uterine fibroids. Radical operations for uterine fibroids cause an increase in the proportion of urogenital disorders, the clinical manifestations of which have a negative impact on the physical, psycho-emotional form and social significance of women in society. A survey of 80 women aged 40 to 50 years, the main group included 40 patients who underwent vaginal hysterectomy, the comparison group consisted of 40 patients with hysterectomy performed by abdominal access. Data on the assessment of pelvic floor condition and urogenital dysfunction using a standardized POP-Q system, both at the stage of preoperative observation and for 3 and 5 years after surgery. Сonducted surveys, filling diaries of pain, urination, physical examination and bimanual examination, determination of the pH of the vaginal contents, colposcopy, evaluated the index of the vaginal condition, the state of the microbiota of the mucous membranes, a comprehensive urodynamic examination, cystometry, ultrasound examination of the pelvic organs and assessment of ovarian structure.The most important risk factors are identified, which would allow to form groups of patients that require individualized approaches in the choice of surgical techniques and rehabilitation program. These included obstetric and gynecological history (birth of large fetuses, episiotomies, birth injuries, high birth parity); ovarian surgery, the use of gonadotropin-releasing hormone agonists. chronic diseases of the respiratory system and gastrointestinal tract, accompanied by increased intra-abdominal pressure; the presence of stigmas of undifferentiated connective tissue dysplasia; clinical manifestations of pelvic floor failure and functional disorders of the urethral sphincter. When choosing a method and access in case of surgical treatment for uterine fibroids, it is advisable to take into account the presence of pelvic prolapse and initial dysuric manifestations in women, the functional state of the sphincter apparatus and urethral hypermobility, obstetric and gynecological pathology and previous surgery on the organs of the uterus. the patient, her awareness of possible complications, the surgeon’s experience and his choice of surgical techniques.


2018 ◽  
pp. 98-101
Author(s):  
A.E. Dubchak ◽  
◽  
O.V. Milevskiy ◽  
N.M. Obeid ◽  
◽  
...  

The objective: the study of the psychoemotional state in women with infertility, who underwent surgical treatment on the uterine appendages in the planned and urgent order. Materials and methods. 120 women of reproductive age with a tubal peritoneal factor of infertility and benign ovarian formations, an ectopic pregnancy, who underwent organ-preserving surgical intervention on the uterine appendages (the main group) were examined. Planned surgical treatment was performed in 76 (63.7%) of the examined main group (group 1); In urgent order, 44 (36.7%) patients of the main group (the second group) underwent surgical treatment. Depending on the access, laparoscopy (LP) with the use of monopolar or bipolar electrosurgery was performed in 54 women of the 1st group and in 24 patients of the 2nd group, and laparotomy (LT) in 22 patients of the 1st group and in 20 patients - 2 nd group. The control group included 20 patients with reproductive function without infertility (3rd group). Twenty women of reproductive age with infertility without surgery entered the comparison group (group 4). Results The article examines the effect of surgical treatment on the uterine appendages in 120 women with infertility on the psychoemotional state depending on the planned nature of the surgical intervention. Women who underwent surgical treatment in urgent order found that pronounced depression and neurotic manifestations are closely related to sleep disturbances, decreased mood, crying, irritability. Conclusion. A month after surgery, depression, anxiety, nervousness decreased, which indicates positive changes in the mental state of patients and an improvement in the state of internal comfort as a result of the recovery of somatic well-being, increased optimism and self-confidence, which is the result of cosmetic effect and organ-preserving surgical treatment. Key words: infertility, operations on the appendages of the uterus, psychoemotional state


Author(s):  
M. Negmatullaeva ◽  
◽  
M. Hamdamova ◽  
M. Hatamova

Uterine myoma is relatively rare in women aged 20-30, but disease risk increases significantly after the age of 35-40. The need to preserve fertility occurs in women of late reproductive age with uterine myoma also increases. Conservative myomectomy is considered to be the method of choice for surgical treatment of uterine myomas in reproductive period. The article describes types and techniques of conservative myomectomy.


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