scholarly journals Chest CT-Scan Findings of an Iraqi Patient with Symptomatic Covid-19 Disease

2021 ◽  
Vol 2 (4) ◽  
pp. 01-04
Author(s):  
Aamir Jalal Al Mosawi
Keyword(s):  
Ct Scan ◽  
School Teacher ◽  
Chest Ct ◽  
Ground Glass ◽  
Ministry Of Health ◽  
Chest Ct Scan

Background: On the first of June, 2021, 1,201,352 cases of covid-19 were reported by the Iraqi Ministry of Health, and 16375 patients died because of the disease. The aim of this paper is to describe chest CT-scan findings of an Iraqi patient who was observed early during June, 2021, and had symptomatic covid-19, but he didn’t need hospitalization. Patients and methods: A forty-year old school teacher developed covid-19 disease with fever, fatigue, anorexia, and cough. The patient recovered after about two weeks. Results: Chest CT-scan performed during first week of illness showed: (1) Multiple bilateral ground glass opacities. (2) Atelectatic bands. (3) Thickening of the interlobular septa. (4) Vascular thickening. Conclusion: The chest CT-scan findings in this Iraqi patient was rather typical of covid-19 disease and included the most commonly reported abnormality of ground-glass shadows.

scholarly journals Correlations of CT scan with high-sensitivity C-reactive protein and D-dimer in patients with coronavirus disease 2019

2020 ◽  
Vol 36 (6) ◽  
Author(s):  
Jin Zhu ◽  
Cheng Chen ◽  
Rongshu Shi ◽  
Bangguo Li
Keyword(s):  
Ct Scan ◽  
High Sensitivity ◽  
Chest Ct ◽  
Ground Glass ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Group 2 ◽  
Chest Ct Scan ◽  
D Dimer ◽  
Group 1

Objectives: To study the correlations of CT scan with high-sensitivity C-reactive protein (hs-CRP) and D-dimer in patients with coronavirus disease 2019 (COVID-2019). Methods: From January to March 2020, COVID-19 patients were divided into two groups according to the Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (trial version 7), with mild and ordinary cases as Group-1 and critical and severe cases as Group-2. The chest CT scan results, hs-CRP, D-dimmer levels of the two groups from admission to discharge were compared by the c2 test or Fisher’s exact test. The quantitative data were represented as mean ± standard deviation (±s). Intergroup comparisons were performed by the independent samples t test, and the ineligible data were subjected to the nonparametric rank sum test. Binary logistic regression model was used for multivariate correlation analysis, using independent variables that were significant in univariate analysis. The correlations between the above indices were analyzed. Results: In Group-1, there were two cases of normal chest CT scan results, one case of fibrosis, and 25 cases of abnormalities during the first diagnosis, mainly manifested as single or scattered ground-glass shadows. After treatment, the CT scan results became normal. The chest CT scan of Group-2 showed abnormalities, including 21 cases of multiple ground-glass shadows, and six cases of multiple consolidations accompanied by ground-glass shadows, who were critically ill and died. In addition, there were 16 cases of multiple ground glass shadows with partial consolidation, and the CRP and D-dimer levels of Group-2 were significantly higher than those of Group-1. Chest CT scan results were significantly positively correlated with CRP and D-dimer levels (P<0.05). Conclusion: The chest CT scan results of COVID-19 patients are characteristic, being correlated with CRP and D-dimer levels. D-dimer and CRP levels significantly increase in most severe and critical patients, which are closely related to their prognosis. The indices may play predictive roles in clinical treatment and prognosis evaluation. doi: https://doi.org/10.12669/pjms.36.6.2961 How to cite this:Zhu J, Chen C, Shi R, Li B. Correlations of CT scan with high-sensitivity C-reactive protein and D-dimer in patients with coronavirus disease 2019. Pak J Med Sci. 2020;36(6):1397-1401. doi: https://doi.org/10.12669/pjms.36.6.2961 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals The Spectrum of Chest CT-Scans in the Hospitalized Patients with the Coronavirus Disease

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Maria Shirvani ◽  
Alireza Janbakhsh ◽  
Feizollah Mansouri ◽  
Babak Sayad ◽  
Siavash Vaziri ◽  
...  
Keyword(s):  
Ct Scan ◽  
Clinical Symptoms ◽  
Large Family ◽  
Chest Ct ◽  
Hospitalized Patients ◽  
Ct Scans ◽  
Ground Glass ◽  
Sample Population ◽  
Ground Glass Opacification ◽  
Chest Ct Scan

Background: Coronaviruses are a large family of RNA viruses, which range from the common cold virus to the causative agent of more severe diseases. Coronavirus was declared a pandemic in December 2019 in Wuhan, China. Iran has been an endemic zone for the spread of the coronavirus since the outset of this global epidemic and has remained among the countries largely affected by high rates of the disease. Objectives: The present study aimed to investigate the range of the chest computed tomography (CT) scan findings among the hospitalized patients with COVID-19 in Kermanshah, Iran during March-April 2020 to contribute to the accurate diagnosis of the infected patients. Methods: The sample population consisted of 286 hospitalized patients diagnosed with or suspected of the coronavirus disease. Chest CT-scan images and clinical data were reviewed, and their correlation was analyzed. Results: In total, 176 patients (61.53%) were male, and 110 (38.47%) were female. The mean age of the patients was 56 years. Polymerase chain reaction (PCR) results showed that 35.31% of the cases had coronavirus, while the results were negative in 64.69% of the cases. In addition, the CT-scan findings indicated 77.27% abnormal and 22.73% normal chest CT-scans. Among the patients, 75.87% recovered completely, and 18.53% died. The major CT abnormalities were diffuse ground-glass opacification (35.66%), peripheral ground-glass opacification (bilateral; 21.33%), and a combination of diffuse and peripheral ground-glass lesions (18.88%). The consolidation lesion of one lobe was detected in 16 patients, and the consolidation lesion of more than one lobe was observed in 40 patients. Conclusions: According to the results, the most common chest CT-scan findings in COVID-19 include diffuse ground-glass opacification, peripheral ground-glass opacification (bilateral), central ground-glass opacification (bilateral), a combination of diffuse and peripheral ground-glass opacification, a combination of central and peripheral ground-glass opacification, the consolidation lesion of one lobe, and the consolidation lesion of more than one lobe. Furthermore, significant correlations were observed between the CT-scans and the main clinical symptoms, while no significant correlations were denoted between the chest CT-scan and PCR results.

scholarly journals Spectrum of Ground Glass Opacities in Chest CT of COVID-19 Patients in Karbala, Iraq

2020 ◽  
Vol 6 (3) ◽  
Author(s):  
Dhia Mahdey Alghazali ◽  
Maytham A Maamera ◽  
Haider Fadel Alkazraji ◽  
Ali A Abutiheen
Keyword(s):  
Ct Scan ◽  
Cross Sectional Study ◽  
Chest Ct ◽  
Ground Glass ◽  
P Value ◽  
Late Time ◽  
Chi Square ◽  
Cross Sectional ◽  
Male Predominance ◽  
Chest Ct Scan

Objective: To describe the ground-glass opacities (GGO) seen in chest CT scans of COVID-19 patients and to estimate the association between these opacities and the time of clinical presentation. Patients and methods: A cross-sectional study involving 81 COVID-19 confirmed patients in Imam Al-Hussein Medical city in Karbala-Iraq during the period from March 1st to April 20, 2020. Chest CT scan findings were evaluated by 2 radiologists and categorized accordingly. Chi-square test was used for statistical analysis and a P value of less than 0.05 was considered statistically significant. Results: The mean age ± standard deviation of patients was 53.5 ± 17.1 years, with male predominance as 63 (77.8%) of cases were males. Nearly half of the patients were presented within the second week of starting the sign and symptoms. GGO was present in 79 scans (97.5%), followed by consolidation opacity in 29 patients (35.8%). Four types of GGO were described. Bilateral multiple subpleural GGO was the most prevalent type. There was a significant association between late time of patient presentation and more extensive GGO type. Conclusion: Chest CT scan is valuable in the diagnosis and management of COVID-19 cases. The presence of GGO in CT scan of a patient that previously had no chest illness is highly suggestive of COVID-19 disease, different types of GGO were seen. Bilateral confluent type of GGO is associated with more serious and delayed status and warns the need for intensive care unit admission.

scholarly journals Outcome of Pulmonary Spherical Ground-glass Opacities on Ct in Patients With Coronavirus Disease 2019 (Covid-19): A Retrospective Analysis

2020 ◽  
Author(s):  
Wangjia Li ◽  
Liangbo Hu ◽  
Junhao Huang ◽  
Fajin Lv ◽  
Binjie Fu ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Ct Scan ◽  
Retrospective Analysis ◽  
Ct Images ◽  
Chest Ct ◽  
Ground Glass ◽  
Direct Absorption ◽  
Simultaneous Decrease ◽  
Chest Ct Scan

Abstract Background: Pulmonary spherical ground-glass opacities (GGOs) are commonly detected on initial chest CT scan in patients with coronavirus disease 2019 (COVID-19).We aimed to investigate the evolution of spherical GGOs to better understand their clinical significance.Materials and Methods:A retrospective study of 33 consecutive patients with confirmed COVID-19 and pulmonary spherical GGOs was performed from January 21, 2020, to March 6, 2020. The initial and follow-up CT images and clinical data were reviewed. The initial CT manifestations of spherical GGOs and their subsequent changes were mainly evaluated. Results:A total of 101 pulmonary spherical GGOs, including 38 with and 63 without consolidation, were found in 33 patients. Of the 101 spherical GGOs, 71 (70.3%) and 30 (29.7%) showed progression and direct absorption on follow-up CT images, respectively. GGOs with consolidation were more likely to progress than those without (84.2% vs. 61.9%, p = 0.017). The 71 progressed lesions mainly showed an increase in size and/or density and most (70.4%) of them extended toward the pleura and developed from spherical to patchy. Internal consolidation appeared and increased in 18 (25.4%) and 22 (31.0%) lesions, respectively. During absorption, all the previous progressed and directly absorbed lesions exhibited a simultaneous decrease in size and density. On each patient’s final CT, more lesions with progression had a residual mixed GGO (40.8% vs. 6.7%, p = 0.002) and fewer had pure GGO (39.4% vs. 60.0%, p = 0.016) than those with direct absorption.Conclusion: In patients with COVID-19, most pulmonary spherical ground-glass opacities would progress, especially those with consolidation, and develop into patchy, subpleural lesions.

scholarly journals 538. The Role of N-acetylcysteine on Post Covid-19 Pulmonary Fibrosis

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S370-S371
Author(s):  
Bernard Demot ◽  
Kristin Ivan Mark Hizon
Keyword(s):  
Pulmonary Fibrosis ◽  
Ct Scan ◽  
Chest Ct ◽  
Ct Scans ◽  
Ground Glass ◽  
Nasopharyngeal Swab ◽  
High Dose ◽  
Pulmonary Consolidation ◽  
Chest Ct Scan

Abstract Background Covid 19 have long lasting complications, from myalgia, body weakness to life debilitating strokes, and pulmonary fibrosis. Several mechanisms had been described but mostly viral or autoimmune which causes damages which leads to Acute respiratory distress syndrome. There is no approved treatment as of this time. Antifibrotic drugs use had been limited due to hepatoxicity, on top of Covid 19 hepatopathy. This study aims to describe the role of N-acetylcysteine on Post COVID 19 pulmonary fibrosis as an alternative treatment. Methods Patients are admitted at Baguio General Hospital and Medical Center at the COVID wards. Patients are COVID confirmed by RT PCR nasopharyngeal swab. Patient who are classified as severe were given Dexamethasone, Enoxaparin and Remdesivir for 5-10 days. Patients who are not weaned off from O2 support underwent Chest CT scan. Patients with Extensive Fibrosis were then consented to undergo High Dose IV Infusion of N-acetylcysteine. (150mg/kg in 1st hour, 50mg/kg next 4 hours and 100mg/kg last 20 hours). Repeat Chest CT Scan was done. Results Peripheral Bilateral Ground Glass Opacities and Pulmonary Consolidation was seen on pre-treatment CT Scans. Repeat CT scans showed significant regression of Ground Glass Opacities and Pulmonary Consolidation. CT SCAN pre and post treatment Conclusion High dose N-acetylcysteine showed promising results on Post COVID 19 Pulmonary Fibrosis. Disclosures All Authors: No reported disclosures

scholarly journals Chest CT features of COVID-19 in the region of Abu Dhabi, UAE- A single institute study

2020 ◽  
Author(s):  
Ghufran Aref Saeed ◽  
Abeer Ahmed Al Helali ◽  
Safaa Almazrouei ◽  
Asad Shah ◽  
Luai A. Ahmed
Keyword(s):  
Ct Scan ◽  
Diagnostic Performance ◽  
Chest Ct ◽  
Abu Dhabi ◽  
Ground Glass ◽  
Rt Pcr ◽  
Negative Results ◽  
Chest Ct Scan ◽  
Ct Features ◽  
Pcr Test

AbstractOBJECTIVEOur aim is to investigate high resolution CT features of COVID-19 infection in Abu Dhabi, UAE, and to compare the diagnostic performance of CT scan with RT-PCR test.METHODSData of consecutive patients who were suspected to have COVID-19 infection and presented to our hospital, was collected from March 2, 2020, until April 12, 2020. All patients underwent RT-PCR test; out of which 53.8% had chest CT scan done. Using RT-PCR as a standard reference, the sensitivity and specify of CT scan was calculated. We also analyzed the most common imaging findings in patients with positive RT-PCR results.RESULTSThe typical HRCT findings were seen in 50 scans (65.8%) out of total positive ones; 44 (77.2%) with positive RT-PCR results and 6 (31.6%) with negative results. The peripheral disease distribution was seen in 86%, multilobe involvement in 70%, bilateral in 82%, and posterior in 82% of the 50 scans.The ground glass opacities were seen in 50/74 (89.3%) of positive RT-PCR group. The recognized GGO patterns in these scans were: rounded 50%, linear 38%, and crazy-paving 24%.Using RT-PCR as a standard of reference, chest HRCT scan revealed sensitivity of 68.8% and specificity of 70%.CONCLUSIONThe commonest HRCT findings in patients with COVID-19 pneumonia were peripheral, posterior, bilateral, multilobe rounded ground glass opacities.

scholarly journals Gambaran Hasil CT-Scan Toraks pada Pasien Coronavirus Disease 2019 (COVID-19)

e-CliniC ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Claudia R. E. Malaru ◽  
Alfa G. E. Y. Rondo ◽  
Christilia G. Wagiu
Keyword(s):  
Computed Tomography ◽  
Severe Acute Respiratory Syndrome ◽  
Literature Review ◽  
Ct Scan ◽  
Chest Ct ◽  
Ground Glass ◽  
Computed Tomography Scan ◽  
First Case ◽  
Tomography Scan ◽  
Chest Ct Scan

Abstract: Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Indonesia reported its first case in March 2, 2020. Cases are increasing and spreading rapidly throughout Indonesia. One of the main imaging modalities for examination of COVID-19 is chest computed tomography scan (CT-scan) which plays an important role in detection, evaluation of severity, and follow-up of disease course. This study was aimed to obtain the description of CT scan results in patients with COVID-19. This was a literature review study using three databases, namely Pubmed, ClinicalKey, and ScienceDirect. The keywords used were COVID-19 AND Chest CT. Based on inclusion and exclusion criteria, there were 10 literatures selected. It was found that chest CT results could accurately evaluate the features and extent of lung lesions. The typical CT-scan results were ground-glass opacities (GGO), GGO with mixed consolidation, adjacent pleural thickening, interlobular septal thickening, and air bronchogram. Based on age, sex, and comorbidities, there was not any significant differences in chest CT findings. In conclusion, GGO, air bronchogram, and consolidation were found in chest CT-scan of COVID-19 patients. Meanwhile, based on age, sex, and comorbidities there were no significant differences in chest CT-scan.Keywords: COVID-19, chest CT-scan Abstrak: Coronavirus disease 2019 (COVID-19) merupakan suatu penyakit menular yang disebabkan oleh severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Indonesia melaporkan kasus pertama pada tanggal 2 Maret 2020. Kasus meningkat dan menyebar dengan cepat di seluruh wilayah Indonesia. Salah satu modalitas pencitraan utama yang menjadi pilihan untuk pemeriksaan COVID-19 ialah Computed Tomography Scan (CT-scan) toraks yang berperan penting dalam deteksi, evaluasi keparahan, dan tindak lanjut perjalanan penyakit. Penelitian ini bertujuan untuk mengetahui gambaran hasil CT-scan pada pasien COVID-19. Jenis penelitian ialah literature review dengan pencarian data menggunakan tiga database yaitu Pubmed, ClinicalKey, ScienceDirect. Kata kunci yang digunakan yaitu COVID-19 AND Chest CT. Hasil seleksi berdasarkan kriteria inklusi dan eksklusi mendapatkan 10 literatur. Didapatkan hasil CT-scan toraks dapat secara akurat mengevaluasi fitur dan luas lesi paru dan CT-scan yang khas ialah ground-glass opacities (GGO), GGO dengan konsolidasi campuran, penebalan pleura yang berdekatan, penebalan septum interlobular, dan bronkogram udara. Pada temuan CT-scan toraks berdasarkan usia, dan jenis kelamin tidak didapatkan perbedaan bermakna. Simpulan penelitian ini ialah terdapat GGO, air bronchogram, dan konsolidasi pada CT-scan toraks pasien COVID-19 sedangkan berdasarkan usia, jenis kelamin, dan komorbid tidak ditemukan perbedaan bermakna.Kata kunci: COVID-19, CT-scan toraks

Cancer surgery during the COVID‐19 pandemic: The experience of a comprehensive cancer center performing preoperative screening by RT‐PCR and chest CT scan

2021 ◽  
Vol 123 (4) ◽  
pp. 815-822
Author(s):  
Joanne Guerlain ◽  
Fabienne Haroun ◽  
Alexandra Voicu ◽  
Charles Honoré ◽  
Franck Griscelli ◽  
...  
Keyword(s):  
Ct Scan ◽  
Chest Ct ◽  
Cancer Surgery ◽  
Comprehensive Cancer Center ◽  
Cancer Center ◽  
Preoperative Screening ◽  
Rt Pcr ◽  
Chest Ct Scan

scholarly journals A meta-analysis of accuracy and sensitivity of chest CT and RT-PCR in COVID-19 diagnosis

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Fatemeh Khatami ◽  
Mohammad Saatchi ◽  
Seyed Saeed Tamehri Zadeh ◽  
Zahra Sadat Aghamir ◽  
Alireza Namazi Shabestari ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Reverse Transcriptase ◽  
Ct Scan ◽  
Predictive Value ◽  
Meta Analysis ◽  
Chest Ct ◽  
Rt Pcr ◽  
Chain Reaction ◽  
Polymerase Chain ◽  
Chest Ct Scan

AbstractNowadays there is an ongoing acute respiratory outbreak caused by the novel highly contagious coronavirus (COVID-19). The diagnostic protocol is based on quantitative reverse-transcription polymerase chain reaction (RT-PCR) and chests CT scan, with uncertain accuracy. This meta-analysis study determines the diagnostic value of an initial chest CT scan in patients with COVID-19 infection in comparison with RT-PCR. Three main databases; PubMed (MEDLINE), Scopus, and EMBASE were systematically searched for all published literature from January 1st, 2019, to the 21st May 2020 with the keywords "COVID19 virus", "2019 novel coronavirus", "Wuhan coronavirus", "2019-nCoV", "X-Ray Computed Tomography", "Polymerase Chain Reaction", "Reverse Transcriptase PCR", and "PCR Reverse Transcriptase". All relevant case-series, cross-sectional, and cohort studies were selected. Data extraction and analysis were performed using STATA v.14.0SE (College Station, TX, USA) and RevMan 5. Among 1022 articles, 60 studies were eligible for totalizing 5744 patients. The overall sensitivity, specificity, positive predictive value, and negative predictive value of chest CT scan compared to RT-PCR were 87% (95% CI 85–90%), 46% (95% CI 29–63%), 69% (95% CI 56–72%), and 89% (95% CI 82–96%), respectively. It is important to rely on the repeated RT-PCR three times to give 99% accuracy, especially in negative samples. Regarding the overall diagnostic sensitivity of 87% for chest CT, the RT-PCR testing is essential and should be repeated to escape misdiagnosis.

scholarly journals Diagnostic performance of chest CT in differentiating COVID-19 from other causes of ground-glass opacities

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Ali H. Elmokadem ◽  
Dalia Bayoumi ◽  
Sherif A. Abo-Hedibah ◽  
Ahmed El-Morsy
Keyword(s):  
Diagnostic Performance ◽  
Pulmonary Nodules ◽  
Ground Glass Opacity ◽  
Chest Ct ◽  
Ground Glass ◽  
Rt Pcr ◽  
Laboratory Findings ◽  
Halo Sign ◽  
Traction Bronchiectasis ◽  
Chest Ct Scan

Abstract Background To evaluate the diagnostic performance of chest CT in differentiating coronavirus disease 2019 (COVID-19) and non-COVID-19 causes of ground-glass opacities (GGO). Results A total of 80 patients (49 males and 31 females, 46.48 ± 16.09 years) confirmed with COVID-19 by RT-PCR and who underwent chest CT scan within 2 weeks of symptoms, and 100 patients (55 males and 45 females, 48.94 ± 18.97 years) presented with GGO on chest CT were enrolled in the study. Three radiologists reviewed all CT chest exams after removal of all identifying data from the images. They expressed the result as positive or negative for COVID-19 and recorded the other pulmonary CT features with mention of laterality, lobar affection, and distribution pattern. The clinical data and laboratory findings were recorded. Chest CT offered diagnostic accuracy ranging from 59 to 77.2% in differentiating COVID-19- from non-COVID-19-associated GGO with sensitivity from 76.25 to 90% and specificity from 45 to 67%. The specificity was lower when differentiating COVID-19 from non-COVID-19 viral pneumonias (30.5–61.1%) and higher (53.1–70.3%) after exclusion of viral pneumonia from the non-COVID-19 group. Patients with COVID-19 were more likely to have lesions in lower lobes (p = 0.005), peripheral distribution (p < 0.001), isolated ground-glass opacity (p = 0.043), subpleural bands (p = 0.048), reverse halo sign (p = 0.005), and vascular thickening (p = 0.013) but less likely to have pulmonary nodules (p < 0.001), traction bronchiectasis (p = 0.005), pleural effusion (p < 0.001), and lymphadenopathy (p < 0.001). Conclusions Chest CT offered reasonable sensitivity when differentiating COVID-19- from non-COVID-19-associated GGO with low specificity when differentiating COVID-19 from other viral pneumonias and moderate specificity when differentiating COVID-19 from other causes of GGO.

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