scholarly journals Efficiency of meloxicam application in complex treatment of patients with osteoarthrosis combined with hypertension

Pain medicine ◽  
2019 ◽  
Vol 4 (1/1) ◽  
pp. 4
Author(s):  
L P Kuznecova ◽  
M. V. Bondar
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Monitoring ◽  
Pain Syndrome ◽  
Well Being ◽  
Knee Joints ◽  
Duration Of Treatment ◽  
Outpatient Settings ◽  
Degrees Of Severity ◽  
Positive Effect

Objective: To evaluate the efficacy of the therapy performed 12 months after initiation of treatment in patients with osteoarthrosis (OA) combined with hypertension (GC) with treatment with meloxicam at a dose of 7.5 mg/day and 80 mg/day and 160 mg/day "difores". Materials and methods: under observation in outpatient settings, there were 60 patients on OA 1–2 stages, in combination with GC 2 degree, 2–3 degrees. The average age of patients with OA was 64.4 ± 7.5 years, patients with OA in combination with GC – 62.13 ± 8.2 years – 41 (68.3 %) women and 19 (31.7 %) men. Duration of the disease was in patients with OA – (9.66 ± 4.7) years, in patients with a comorbidity of OA and GC – (9.4 ± 6.0) years, respectively. To perform the research tasks, all patients were divided into 3 groups of 30 patients in each of them. The first group – patients with OA without GC, the second one – patients with a combination of OA and GC, the third group of comparison contained practically healthy persons. All patients complained of pain syndrome of varying degrees of severity. Patients of the first two groups received methoxy at a dose of 7.5 mg per day as baseline therapy; meloxicam and antihypertensive drug "diforsi" at a dose of 80 mg per day – patients in the second group were taken, but in 29 % of patients in this group "diormos" was prescribed at a dose of 160 mg. Duration of treatment was 12 months. A general clinical examination was performed inall patients at the beginning of the study, and after treatment: general blood tests, office blood pressure measurements, electrocardiography (ECG), daily blood pressure monitoring (DMAT), radiography of the knee joints. Results: According to the results, the positive effect of using meloxicam caused a significant decrease in the severity of pain in the first and second groups according to the visual analog scale (VAS): (by 27.8 % and 29.8 % respectively, p < 0.05) and the Lequesne index (respectively 27.1 % and 30.9 %, p < 0.05). Also, the analgesic and anti-inflammatory effect of meloxicam and its positive effect on the clinical course of OA were revealed: joint pain decreased, functional capacity in-creased, general well-being and quality of life of patients improved.

scholarly journals Improvement of complex treatment of patients with osteoarthritis combined with hypertension

Pain medicine ◽  
2019 ◽  
Vol 4 (1/1) ◽  
pp. 5
Author(s):  
L P Kuznecova ◽  
M V Bondar
Keyword(s):  
Quality Of Life ◽  
Conflict Of Interest ◽  
Age Groups ◽  
Pain Syndrome ◽  
Well Being ◽  
Outpatient Setting ◽  
Social Significance ◽  
Duration Of Treatment ◽  
Positive Effect

Actuality: Among the diseases that significantly affect people, osteoarthritis (OA) takes 4th place in women and 8th in men. In both sexes older than 70 years, osteoarthrosis occurs in almost everyone, and in the last decade its prevalence has steadily increased. The social significance of OA is determined by the increase in disability, especially in older age groups, as well as by a sharp decline in the quality of life for this. Objective: To evaluate the efficacy of the therapy performed 12 months after initiation of treatment in patients with hypertension (GC) on the background of treatment with meloxicam at a dose of 7.5 mg/day and 80 and 160 mg/day. Material and methods: under supervision in an outpatient setting, there were 90 patients on the OA 1–2 stages, in combination with GC 2 degree, 2–3 degrees. The average age of patients with OA was 64.4 ± 7.5 years (the first group), patients with OA in combination with GC – 62.13 ± 8.2 years (second group), patients with OA in combination with GC and gastropathy due to admission NSAIDs (third group) – 64.81 ± 1.3 years. Disease duration in patients of the first group – (9.66 ± 4.7) years, in patients of the second group – (9.4 ± 6.0) years, in patients of the third group – (10.4 ± 5.6) years, respectively, the fourth group of comparison contained practically healthy persons. All patients complained of pain syndrome of varying degrees of severity. Patients in the first group received baseline therapy of meloxicam at a dose of 7.5 mg/day; patients in the second and third groups received meloxicam and antihypertensive drug (at a dose of 80 or 160 mg per day). Duration of treatment was 12 months. Results of the study and their discussion: according to the results, the positive effect of the use of meloxicam has led to a significant decrease in the severity of pain in the first, second and third groups according to the visual analogue scale (VAS): (27.8 %, 29.8 %, 25.4 %, p < 0.05) and the Lequesne index (27.1 % and 30.9 %, 26.4 %, p < 0.05), respectively. Conclusions: The tested scheme of treatment of patients with OA with the use of meloxicam indicates the efficacy and statistically significant reduction of pain syndrome, improvement of the functional state of the musculoskeletal system in patients with OA as well as with OA in combination with GC. 2.Also, the analgesic and anti-inflammatory effect of meloxicam and its positive effect on the clinical course of OA were revealed: joint pain decreased, functional capacity increased, general well-being and quality of life of patients improved. Prospects for further research: We consider it expedient to continue prospective surveillance of patients with the aim of further studying of the effect of meloxicam in patients with a comorbid disease. Conflict of Interest: There is no conflict of interest.

Correlazioni positive tra spiritualità e salute: i risultati di alcune indagini / Positive correlations between spirituality and health: results from some surveys

2019 ◽  
Vol 68 (1) ◽  
pp. 41-54
Author(s):  
Paolo Morocutti
Keyword(s):  
Quality Of Life ◽  
Health Personnel ◽  
Medical Condition ◽  
Well Being ◽  
Close Correlation ◽  
General Medical Condition ◽  
Spirituality And Health ◽  
Positive Correlations ◽  
Positive Effect

La dimensione religiosa dell’uomo contribuisce in modo sostanziale al mantenimento della condizione medica generale, migliorando e preservando la qualità della vita. Quanto fa bene la fede? La preghiera fa ammalare meno e guarire prima? La partecipazione ai servizi religiosi porta realmente un effetto positivo sulla salute? Gli studi esaminati in questo articolo sembrano rispondere affermativamente a queste domande, evidenziando la stretta correlazione tra religiosità/spiritualità, salute e benessere fisico e psicologico. L’impatto antropologico e sociologico di tale realtà conduce ad evidenti riflessioni storiche e filosofiche, ma anche mediche e bioetiche, generando l’esigenza di una profonda trasformazione nella formazione del personale sanitario, dove l’aspetto religioso o spirituale non è ritenuto importante, né rilevante nell’approccio medico per la cura e l’assistenza del paziente. Nonostante ciò, numerosi studi approfondiscono ed attestano l’importanza di questo aspetto sia dei singoli, sia dell’intera popolazione. ---------- Religious dimension of man contributes substantially to maintain general medical condition, improving and preserving quality of life. How good is faith? Does prayer make you sick less and get better sooner? Does participation in religious services actually have a positive effect on health? The studies examined within this article seem to answer positively to these questions, highlighting the close correlation between religiosity / spirituality, health and physical and psychological well-being. The anthropological and sociological impact of this reality leads to evident historical and philosophical as well as medical and bioethical reflections, generating the need for a deep transformation of health personnel training, where the religious or spiritual aspect are not considered as important, nor relevant for medical approach to patient’s care. Nevertheless, several studies address and highlight the importance of this aspect for both individuals and whole population.

scholarly journals Quality of antenatal care and associated factors in a rural county in Kenya: an assessment of service provision and experience dimensions

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Patience A. Afulani ◽  
Laura Buback ◽  
Francisca Essandoh ◽  
Joyceline Kinyua ◽  
Leah Kirumbi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Antenatal Care ◽  
Service Provision ◽  
Blood Pressure Monitoring ◽  
Urine Test ◽  
Information Communication ◽  
Experience Of Care ◽  
The Individual ◽  
Recommended Services

Abstract Background This study aimed to assess the quality of antenatal care (ANC) women received in Migori county, Kenya—including both service provision and experience dimensions—and to examine factors associated with each dimension. Methods We used survey data collected in 2016 in Migori county from 1031 women aged 15–49 who attended ANC at least once in their most recent pregnancy. ANC quality service provision was measured by nine questions on receipt of recommended ANC services, and experience of care by 18 questions on information, communication, dignity, and facility environment. We summed the responses to the individual items to generate ANC service provision and experience of care scores. We used both linear and logistic regression to examine predictors. Results The average service provision score was 10.9 (SD = 2.4) out of a total of 16. Most women received some recommended services once, but not at the frequency recommended by the Kenyan Ministry of Health. About 90% had their blood pressure measured, and 78% had a urine test, but only 58 and 14% reported blood pressure monitoring and urine test, respectively, at every visit. Only 16% received an ultrasound at any time during ANC. The average experience score is 27.3 (SD = 8.2) out of a total score of 42, with key gaps demonstrated in communication. About half of women were not educated on pregnancy complications. Also, about one-third did not often understand the purposes of tests and medicines received and did not feel able to ask questions to the health care provider. In multivariate analysis, women who were literate, employed, and who received all their ANC in a health center had higher experiences scores than women who were illiterate (coefficient = 1.52, CI:0.26,2.79), unemployed (coefficient = 2.73, CI:1.46,4.00), and received some ANC from a hospital (coefficient = 1.99, CI: 0.84, 3.14) respectively. The wealthiest women had two times higher odds of receiving an ultrasound than the poorest women (OR = 2.00, CI:1.20,3.33). Conclusion Quality of ANC is suboptimal in both service provision and experience domains, with disparities by demographic and socioeconomic factors and facility type. More efforts are needed to improve quality of ANC and to eliminate the disparities.

scholarly journals Recurrent swelling and pain in the abdomen and joints in a patient with hereditary angioedema and Ehlers-Danlos syndrome

2019 ◽  
Vol 12 (11) ◽  
pp. e231484
Author(s):  
My-Trang Thi Dang ◽  
Andrew Ambort ◽  
Annie Arrey-Mensah
Keyword(s):  
Quality Of Life ◽  
Hereditary Angioedema ◽  
Healthcare Providers ◽  
Pain Syndrome ◽  
Well Being ◽  
Type I ◽  
Ehlers Danlos Syndrome ◽  
Complex Disorders ◽  
Danlos Syndrome

A 23-year-old woman was referred to the allergy and immunology clinic for recurrent abdominal, cutaneous and joint swelling and pain with a history of mucosal infections since childhood. Her history and clinical findings were suggestive of two rare and complex disorders, hereditary angioedema (HAE) and Ehlers-Danlos syndrome (EDS). Her recurrent episodes of abdominal and joint pain were initially misattributed to more common diagnoses such as esophagitis, depression and chronic pain syndrome. However, the coexistence of HAE and EDS likely contributed to a delay in diagnoses as the combination of these two rare but overlapping disorders is less understood by physicians. She had persistently low levels of C4 and C1-esterase inhibitor (C1-INH) with low to low-normal C1-esterase function, normal C1Q and no C1Q antibodies. In the setting of recurrent abdominal pain with cutaneous swelling, this supported the diagnosis of HAE type I. The increase in joint extensibility with recurrent shoulder subluxations since childhood was a manifestation of EDS. Although no known genetic mutations were identified for EDS, her diagnosis was confirmed by a geneticist based on her clinical phenotype. Before the diagnosis of HAE and EDS, our patient had at least 100 visits/year to the emergency department/hospitalisations for these recurrent symptoms. After starting on C1-INH replacement therapy, the frequency has decreased 10-fold. She also noted a 70% improvement in her quality of life. Familiarity with these rare disorders will assist healthcare providers in recognising HAE and EDS and include them as part of their differential diagnoses. Early diagnosis is important for a patient’s well-being as both these chronic disorders have been associated with poor quality of life. Additionally, proper diagnoses will reduce healthcare costs by preventing unnecessary procedures due to misdiagnoses. Proper treatment will help to decrease hospitalisations and avoidance of life-threatening consequences (such as asphyxiation from fatal laryngeal attacks of HAE and rupture of aneurysms in EDS).

scholarly journals EFFECTS OF HAPPINESS TRAINING ON MENTAL HEALTH IN ADULTS: A SYSTEMATIC REVIEW

2021 ◽  
Vol 6 (38) ◽  
pp. 93-109
Author(s):  
Sonia Khodabakhsh
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Systematic Review ◽  
Blood Pressure ◽  
Life Satisfaction ◽  
Web Of Science ◽  
Review Paper ◽  
Well Being ◽  
Research Articles

Past studies have shown mental health and happiness are associated with each other. Several studies were done on the effectiveness of happiness training in several aspects. In this review paper, the effect of happiness training on mental health among adults is systematically reviewed. Through a search in Web of Science, PubMed, and Google Scholar using the “happiness training” keyword and its related words among post-2005 publications, the number of 18 research articles included in this review paper. Based on the systematic review, 18 variables in the selected studies are discussed which include anxiety, blood pressure, burnout, depression, emotions, flourishing, happiness, life expectancy, life satisfaction, migraine symptoms, mindfulness, quality of life, resilience, stress, tolerance, and well-being.

scholarly journals The influence of intensity and neuropathic component of pain syndrome on the quality of life in patients with multiple sclerosis

2021 ◽  
Vol 23 (5) ◽  
pp. 628-635
Author(s):  
T. I. Nehrych ◽  
N. L. Bozhenko ◽  
M. I. Bozhenko
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Pain Intensity ◽  
Social Functioning ◽  
Pain Syndrome ◽  
Well Being ◽  
Structural Element ◽  
Low Intensity ◽  
Average Pain

The aim of the work. To analyze the influence of intensity and neuropathic component of pain syndrome on the quality of life structure characteristics in patients with multiple sclerosis (MS). Materials and methods. 104 MS patients with different types of MS course and complaints of pain during the last month were examined in the Lviv Regional Multiple Sclerosis Center. The patients were interviewed using standardized questionnaires (Pain Detect, VAS, SF-36) followed by an analysis of the pain characteristics influence on the quality of life. Results. When assessing the influence of the main characteristics of MS course, the relationship between the physical component of quality of life and levels of disability (EDSS) and the total number of relapses was found (r = -0.60, P < 0.01; r = -0.34, P < 0.01, respectively). However, the mental component of quality of life had no significant relationship with the level of disability and the number of relapses. The average pain intensity within a month on the VAS scale was 5.0 [4.0; 7.0]. 24.0 % of patients had low-intensity pain, 54.8 % – moderate, 21.2 % – high. In MS patients with low-intensity pain within a month, 5 of the 11 quality of life indicators were significantly higher, in particular, the overall physical component of quality of life – 38.1 [33.8; 48.5] % in low-intensity pain against 31.8 [28.1; 38.7] %, P = 0.02 – in moderate. In MS patients, the level of both physical (r = -0.25; P = 0.01) and mental (r = -0.21; P = 0.03) component of quality of life decreased with increasing pain intensity. The most notable correlation was observed between intensity of pain and such characteristics of quality of life as energy/fatigue (r = -0.37; P ˂ 0.01) and emotional well-being (r = -0.28; P ˂ 0.01). In 30.8 % of patients, pain was neuropathic, in 47.1 % – nociceptive, in 22.1 % – undetermined. MS patients with the neuropathic type of pain had significantly lower scores, 7 out of 11 indicators of quality of life, largely the mental component, than scores in MS patients with nociceptive type (Р < 0.05). Correlation analysis showed the association between an increase in the manifestation of neuropathic pain component and a decrease in all quality of life characteristics, except in health change. In MS patients with a neuropathic component, in increasing level of its manifestation, the mental component of health decreased clearly (r = -0.36; P ˂ 0.01), namely its social functioning characteristic (r = -0.35; P < 0.01). Conclusions. In MS patients, increasing intensity of pain decreases both physical and mental components of quality of life with the most significant decrease in energy/fatigue and emotional well-being as parts of the mental component of quality of life. The neuropathic component of pain and the level of its manifestation are largely associated with a decrease in the mental component of quality of life as the overall indicator and social functioning as its structural element.

scholarly journals The Distance Monitoring of Blood Pressure as a Tool for Improving of the Quality of Follow-Up Observation of Patients with Arterial Hypertension

2021 ◽  
Vol 11 (4) ◽  
pp. 255-263
Author(s):  
I. A. Starodubtseva ◽  
Yu. A. Sharapova
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
Blood Pressure Monitoring ◽  
Cardiovascular Complications ◽  
Pressure Monitoring ◽  
Blood Pressure Targets ◽  
Distance Counseling ◽  
The Right

This article focuses on the distant blood pressure monitoring for patients with arterial hypertension. As numerous studies show, even slightly elevated blood pressure significantly raises the risk of cardiovascular complications. And, vice versa, a 5 mmHg decrease in blood pressure reduces the lethality risk. Therefore, it is not enough to prescribe the right medication but also it is of paramount importance to monitor patients’ compliance with the treatment. Clinical observation of patients with arterial hypertension is an effective tool for the prevention of cardiovascular complications. However, to date, the coverage of follow-up and the achievement of blood pressure targets in patients with arterial hypertension is one of the most problematic aspects. Distance monitoring of blood pressure opens more opportunities for the doctor’s involvement, timely assessment and adjustment of the medication. The results of domestic and foreign research show high efficacy of the distance blood pressure monitoring. Positive results regarding the achievement of target blood pressure after 3 months are shown when using the technology of blood pressure monitoring and distance counseling of patients with arterial hypertension. In particular, the article considers the technology of mobile health care (mHealth), which is a more flexible platform for a patient’s continuous self-care.

scholarly journals Local use of Muscomed in the treatment of patients with knee osteoarthritis

TRAUMA ◽  
2021 ◽  
Vol 22 (2) ◽  
pp. 28-33
Author(s):  
A.V. Makogonchuk ◽  
Yu.O. Bezsmertnyi ◽  
L.Ye. Atamanchuk
Keyword(s):  
Analogue Scale ◽  
Pain Syndrome ◽  
Knee Joints ◽  
Osteoarthritis Of The Knee ◽  
Efficacy And Safety ◽  
Safety And Efficacy ◽  
Womac Index ◽  
Inflammatory Drugs ◽  
Local Use

The article presents the literature data and the results of our own investigation on the efficacy and safety of Muscomed cream in the treatment of patients with osteoarthritis of the knee joint. The study included 20 women (mean age 62 years). The study design included clinical and radiological examination of patients and survey using the Western Ontario and McMaster Universities Arthritis Index (WOMAC) and the visual analogue scale at the beginning of treatment, on days 7 and 14 of using Muscomed cream. Muscomed cream was applied topically as a component of physiotherapeutic procedures as a part of a comprehensive conservative treatment. Two weeks after completing the course of treatment, there was a significant decrease in the intensity of pain syndrome and a decrease in the total WOMAC index in patients who used Muscomed cream locally. There was also a more pronounced decrease in the need for non-steroidal anti-inflammatory drugs in patients of the main group. The safety and efficacy of the Muscomed cream in the treatment of osteoarthritis of the knee joints were demonstrated, which resulted in a decrease in the severity of pain syndrome and an improvement in the functional activity and quality of life of such patients.

scholarly journals The Association of Health Literacy with High-Quality Home Blood Pressure Monitoring for Hypertensive Patients in Outpatient Settings

2020 ◽  
Vol 2020 ◽  
pp. 1-15 ◽  
Author(s):  
Sau Nga Fu ◽  
Man Chi Dao ◽  
Carlos King Ho Wong ◽  
Bernard Man Yung Cheung
Keyword(s):  
Blood Pressure ◽  
Health Literacy ◽  
Educational Level ◽  
Blood Pressure Monitoring ◽  
Home Blood Pressure ◽  
Limiting Factors ◽  
Home Blood Pressure Monitoring ◽  
Pressure Monitoring ◽  
High Quality

Worldwide hypertension (HT) guidelines recommend use of home blood pressure monitoring (HBPM) in patients with persistent suboptimal blood pressure (BP) readings. It is not clear how patients with limited health literacy could perform HBPM to assist BP control. This study aimed at finding the association between HBPM and patients from lower socioeconomic classes, particularly on the effect of health literacy or educational level. Three electronic databases (MEDLINE, EMBASE, and PubMed) were searched for primary studies with keywords including educational level, health literacy, numeracy, home blood pressure monitoring, accuracy, and quality. The PRISMA guideline was followed. The quality of the literature was assessed by the Cochrane tool and modified Newcastle-Ottawa Scale. Nineteen interventional studies and 29 cross-sectional studies were included. Different populations used different cutoffs to report patients’ educational level, whereas health literacy was rarely measured. Three studies used psychometric validated tools to assess health literacy. The quality of HBPM could be assessed by the completion of the procedures’ checklist or the number of HBPM readings recorded. The association between subjects’ health literacy or educational level and the quality of HBPM was variable. The interventional studies showed that increasing professional-patient contact time could improve patients’ knowledge, efficacy, and quality of HBPM. Conclusion. Patients’ educational level and literacy were not the limiting factors to acquire high-quality HBPM. High-quality HBPM could be achieved by the structured educational intervention. The quality and amount of evidence on this topic are limited. Therefore, further studies are warranted.

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