scholarly journals EFFECT OF SARS-COV-2 ON PREGNANCY AND FETUS (LITERATURE REVIEW)

2021 ◽  
Vol 21 (2) ◽  
pp. 208-213
Author(s):  
О.S. Shkolnyk ◽  
A.M. Shlemkevych ◽  
O.M. Malanchuk ◽  
Yе.B. Sharhorodska ◽  
H.R. Akopyan
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Medical Literature ◽  
Pathological Condition ◽  
Unintended Consequences ◽  
World Health ◽  
Vulnerable Groups ◽  
Necessary Condition ◽  
The World ◽  
The Impact

Aim of the study: analysis of modern medical literature on risk factors for the pathological condition of the fetus in women who had COVID-19 during pregnancy. The authors analyzed the scientific medical literature on the study of the impact of COVID-19 infection on the course and complications of pregnancy and the condition of the fetus. The characteristics of the possible risks of a number of adverse consequences for the mother and child due to the postponed COVID-19 disease are given. In Ukraine, studies of genetic and demographic processes, which were carried out in recent years, have shown that the demographic crisis that is observed in the country is socially determined, significantly deepening due to reproductive losses, which is manifested in an increase in the frequency of lost pregnancies and the birth of inferior offspring in women with pathology of the reproductive system. The low level of reproductive health is largely due to the high level of perinatal losses. In Ukraine, the rate of perinatal and child mortality exceeds the data of European countries. Under these conditions, reducing perinatal mortality, preserving the life and health of newborns is a necessary condition for the demographic development of Ukraine and a factor of national security. COVID-19, a disease caused by Coronavirus 2 Severe Acute Respiratory Syndrome (SARS-CoV-2), has spread rapidly around the world. On March 12, 2020, the World Health Organization has designated the outbreak as a pandemic. Because pregnant women are at greater risk of complications and severe disease, they have been identified as “vulnerable groups”. Changes in the mother's immune system during pregnancy can influence the response to infections, particularly viruses. Pregnant women with COVID-19 may have risk factors for thrombosis, and the adaptation of the mother's vessels during pregnancy is critical for certain periods of pregnancy. The role of the placenta in COVID-19 infection is currently not well-researched. A number of potential mechanisms may be involved in the vertical transmission of viruses from the mother to the trophoblast. Scientists are conducting research on the likelihood of infection with SARS-CoV-2 in utero or during childbirth. The unintended consequences of the COVID-19 pandemic threaten the health of pregnant women. It is likely that the consequences of COVID-19 will be evident in the future for a number of years. Epidemiological information is critical for identifying differential responses of the population and analyzing data on the impact of COVID-19 in socio-economic and ethnic groups. In summary, it will be important to evaluate population-level data from these results to determine trends associated with the COVID-19 pandemic.

scholarly journals The Impact of Ultraviolet Radiation on the Aetiology and Development of Uveal Melanoma

Cancers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1700
Author(s):  
Melissa Chalada ◽  
Charmaine A. Ramlogan-Steel ◽  
Bijay P. Dhungel ◽  
Christopher J. Layton ◽  
Jason C. Steel
Keyword(s):  
Risk Factors ◽  
Ultraviolet Radiation ◽  
Uveal Melanoma ◽  
World Health Organisation ◽  
World Health ◽  
Genetic Mutations ◽  
High Incidence ◽  
The World ◽  
The Impact

Uveal melanoma (UM) is currently classified by the World Health Organisation as a melanoma caused by risk factors other than cumulative solar damage. However, factors relating to ultraviolet radiation (UVR) susceptibility such as light-coloured skin and eyes, propensity to burn, and proximity to the equator, frequently correlate with higher risk of UM. These risk factors echo those of the far more common cutaneous melanoma (CM), which is widely accepted to be caused by excessive UVR exposure, suggesting a role of UVR in the development and progression of a proportion of UM. Indeed, this could mean that countries, such as Australia, with high UVR exposure and the highest incidences of CM would represent a similarly high incidence of UM if UVR exposure is truly involved. Most cases of UM lack the typical genetic mutations that are related to UVR damage, although recent evidence in a small minority of cases has shown otherwise. This review therefore reassesses statistical, environmental, anatomical, and physiological evidence for and against the role of UVR in the aetiology of UM.

scholarly journals Coronavirus Pandemic: Coping with the Psychological Outcomes, Mental Changes, and the “New Normal” During and After COVID-19

2020 ◽  
pp. 07-19
Author(s):  
Hiba Takieddine ◽  
Samaa AL Tabbah
Keyword(s):  
Healthcare Providers ◽  
Well Being ◽  
World Health ◽  
Vulnerable Groups ◽  
Public Health Response ◽  
New Normal ◽  
The World ◽  
Health Organization ◽  
The Impact

Coronavirus disease 2019 (COVID-19) is a highly infectious disease that has rapidly swept across the world, inducing a considerable degree of fear, worry and concern in the population at large and among certain groups in particular, such as older adults, healthcare providers and people with underlying health conditions. Authorities around the world tried to prevent the virus spread by imposing social distancing measures, quarantining citizens and isolating infected persons. Apart from its physical impact, COVID-19 pandemic has brought numerous changes to people’s lives. It changed daily routines, caused worldwide economic crisis, increased unemployment, and placed people under emotional and financial pressures. It affected people psychologically and mentally especially in terms of emotions and cognition. During the acute crisis, everyone to varying degrees experienced fear of infection, somatic concerns, worries about the pandemic’s consequences, loneliness, depression, stress, as well as increased alcohol and drug use. As part of its public health response, the World Health Organization (WHO) has worked with partners to develop a set of new guidelines and messages that can be used to prevent, manage, and support mental and psychological well-being in different vulnerable target groups during the outbreak. Whether people like it or not, the psychological sequela of this pandemic will emerge and persist for months and years to come leading to long-term consequences. New lifestyles and “New Normals” will surely emerge. The main purpose of this review is to summarize the impact of coronavirus pandemic on the psychological and mental health of people around the world especially vulnerable groups. It also presents the relevant intervention actions and recommendations to cope efficiently and effectively with the psychological short-term and long-term outcomes, mental changes, and the “New Normal” during and after COVID-19. Keywords: COVID-19; Coronavirus, Psychological; Mental; New Normal

Traveller's thrombosis: airlines still not giving passengers the WRIGHT advice!

2010 ◽  
Vol 25 (5) ◽  
pp. 257-260 ◽  
Author(s):  
J R H Scurr ◽  
N Ahmad ◽  
D Thavarajan ◽  
R K Fisher
Keyword(s):  
Risk Factors ◽  
Venous Thromboembolism ◽  
Phase 1 ◽  
Medical Advice ◽  
World Health ◽  
Compression Stockings ◽  
Additional Risk ◽  
The World ◽  
International Airlines ◽  
The Impact

Introduction This study has examined the impact of the World Health Organization's Research into Global Hazards of Travel (WRIGHT) Project's phase 1 report on the information given by airlines to their passengers regarding traveller's thrombosis. Methods Official websites of all airlines flying from Heathrow (UK) and John F Kennedy (USA) were located through links on the websites of these two busy international airports. In June 2007, each site was scrutinized by three independent researchers to identify if traveller's thrombosis and its risk factors were discussed and what methods of prevention were advised. This exercise was repeated a year after the publication of the WRIGHT report. Results One hundred and nineteen international airlines were listed in 2007 (12 were excluded from analysis). A quarter (27/107) of airlines warned of the risk of traveller's thrombosis. A year later, five airlines were no longer operational and there had been no increase in the discussion of traveller's thrombosis (23/102). Additional risk factors discussed in June 2007 versus September 2008: previous venous thromboembolism (16%, 15%); thrombophilia (14%, 15%); family history (11%, 9%); malignancy (12%, 14%); recent surgery (19%, 16%); pregnancy (17%, 16%) and obesity (11%, 12%). Prophylaxis advice given in June 2007 versus September 2008: in-flight exercise (34%, 42%); Hydration (30%, 34%); medical consultation prior to flying (20%, 18%); graduated compression stockings (13%, 12%); aspirin (<1%, <1%) and heparin (5%, 7%). Conclusions The majority of world airlines continue to fail to warn of the risk of traveller's thrombosis or offer appropriate advice. Alerting passengers at risk gives them an opportunity to seek medical advice before flying.

scholarly journals Pregnancy and COVID-19, a brief review

2020 ◽  
Vol 5 ◽  
Author(s):  
Olga Vasylyeva
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
World Health ◽  
Virus Spread ◽  
Resource Center ◽  
The Us ◽  
The World ◽  
Total Death ◽  
Novel Coronavirus ◽  
Health Organization

COVID-19 is a novel coronavirus capable of causing a severe acute respiratory syndrome. First identified in December 2019 in Wuhan, China, the virus spread around the world and is characterized as a pandemic by the World Health Organization. According to Johns Hopkins Coronavirus Resource Center, presently total confirmed cases mounted 156,400 with total death of 5,833 around the world, among them 2,952 cases in the US and 57 deaths.  This article summarizes what is presently known about COVID-19 infection in pregnant women, and review unique risk factors for severity of viral illnesses among pregnant women.

Maternal SARS-CoV-2 Infection, Its Vertical Transmission and Impact on Overall Perinatal Outcomes: A Narrative Review

2021 ◽  
Vol 17 ◽  
Author(s):  
Naina Kumar ◽  
Vikas Bhatia
Keyword(s):  
Pregnant Women ◽  
Vertical Transmission ◽  
English Language ◽  
Neonatal Outcome ◽  
Perinatal Outcomes ◽  
Preterm Births ◽  
Neonatal Infection ◽  
World Health ◽  
The World ◽  
The Impact

Background: : COVID-19 pandemic caused by single-stranded RNA containing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) started in early December 2019 from the Wuhan city of China and till date has affected millions of people including pregnant women worldwide. Research from all over the world has shown that the SARS-CoV-2 infection can be transmitted vertically from mother to fetus, but is very rare. Neonatal infection with COVID-19 accounts for only a small proportion of the total population infected. Furthermore, very few studies have observed the impact of maternal SARS-CoV-2 infection on neonatal outcomes. Thus, the literature about neonatal transmission and outcome in COVID-19 infected antenatal women is very scattered and limited. The present review briefs on the transmission of SARS-CoV-2 infection from mother to fetus and its impact on perinatal outcomes. Methodology: : English language articles from various databases including PubMed, Scopus, EMBASE, Scholar, MedRxiv, and Web of Science and from the World Health Organization site were searched from the beginning of the COVID-19 pandemic up to June 2021. The search terms used were “SARS-CoV-2 and pregnancy outcome, “COVID-19 and neonatal outcome”, “Placental changes in COVID-19 infected pregnant women”, “Vertical transmission of COVID-19”. Conclusion: : Maternal SARS-CoV-2 infection can be transmitted to the fetus, though uncommon, and can lead to adverse perinatal outcomes including preterm births, intrauterine growth restriction, NICU admission, stillbirths. The data on transmission and the adverse neonatal outcome is sparse and many more studies are needed to fully understand the mechanism by which maternal COVID-19 infection can affect fetuses and neonates.

scholarly journals From depressive symptoms to depressive disorders: the relevance of thresholds

2010 ◽  
Vol 196 (5) ◽  
pp. 365-371 ◽  
Author(s):  
José L. Ayuso-Mateos ◽  
Roberto Nuevo ◽  
Emese Verdes ◽  
Nirmala Naidoo ◽  
Somnath Chatterji
Keyword(s):  
Risk Factors ◽  
Health Status ◽  
Depressive Episode ◽  
Depressive Disorders ◽  
World Health ◽  
World Health Survey ◽  
The World ◽  
The Unemployed ◽  
Depressive Episodes ◽  
The Impact

BackgroundNosological boundaries for depressive disorders as well as the prevalence and impact of ‘subsyndromal’ depression remain unclear.AimsTo examine the impact of subsyndromal depressive disorders on health status and to assess if depressive disorders lie on a continuum of severity.MethodThe sample was composed of randomly selected respondents from the general population in 68 countries from across the world participating in the World Health Organization's World Health Survey.ResultsThe pattern of risk factors for depressive disorders was consistent across all types of depression (subsyndromal, brief depressive episode and depressive episode): odds ratios for females ranged between 1.49 and 1.80, and for the unemployed from 1.19 to 1.25. All types of depression produced a significant decrement in health status compared with no depression after controlling for demographic variables, income and country.ConclusionsSubthreshold depressive disorders occur commonly all across the world and are associated with the same risk factors everywhere. They produce significant decrements in health and do not qualitatively differ from full-blown episodes of depression as currently defined, and lie on a continuum with more severe forms of depressive episodes but are distinct from normal mood changes.

scholarly journals Prevention of congenital malformations for pregnant women: a predictive model based on a study in eastern Algeria’s population

2021 ◽  
Author(s):  
Adel Kalla ◽  
Lotfi Loucif ◽  
Mouloud Yahia
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Predictive Model ◽  
Congenital Malformations ◽  
World Health ◽  
Analysis Techniques ◽  
Multiple Risk Factors ◽  
The World ◽  
Eastern Algeria ◽  
Health Organization

The World Health Organization (WHO) defines congenital malformation as any gross abnormality present at birth even if it is not immediately recognized. Here, we aimed to identify the factors predisposing to congenital malformations in pregnant women in Eastern Algeria and the effect of the combination of several factors. 786 pregnant women were interviewed. Throughout our study, we sought to find answers, discuss the association between malformation exposure, identify the risk factors, and predict the occurrence of malformations using statistical analysis techniques. We developed a predictive model and we found that malformations were significantly higher for pregnant women aged over 34 (10.93; 95%CI: 2.10-201.71, p=0.023), with a BMI over 25 (2.38; 0.91-7.04, p=0.091), hypertension (2.18; 1.04-4.57, p=0.038), anemia (2.08; 0.98-4.35, p=0.053) and infections (2.32; 1.18-4.58; p=0.015). Protecting factors against malformations includes diet moderate in meat (1.97; 0.73-4.98, p=0.163) and rich in eggs, soft drinks, and fruit-vegetables (2.69; 0.76-8.63, p=0.106), (1.84; 0.74-4.43, p=0.177), (3.08; 0.56-13.28, p=0.154); respectively. Knowing risk factors helps to establish predictive models and strategies to prevent malformations and highlights the link between malformations and multiple risk factors for the sake of protecting babies’ lives.

scholarly journals Analysis of air pollution exposure in the area of Iasi county – a warning signal for lung health and the risk of developing COPD

Pneumologia ◽  
2021 ◽  
Vol 69 (3) ◽  
pp. 166-173
Author(s):  
Ioana Buculei ◽  
Mona-Elisabeta Dobrin ◽  
Anda Tesloianu ◽  
Cristina Vicol ◽  
Radu-Adrian Crișan Dabija ◽  
...  
Keyword(s):  
Risk Factors ◽  
Air Pollution ◽  
Air Quality ◽  
Air Pollutants ◽  
World Health ◽  
Annual Reports ◽  
Chronic Obstructive ◽  
The World ◽  
High Concentrations ◽  
The Impact

Abstract Air pollution is a major threat to public health, and the effects of pollution are perceived in all countries of the world, by all social categories, regardless of age. Chronic obstructive pulmonary disease (COPD) has a growing prevalence worldwide and an increasing number of risk factors that exacerbate symptoms and accelerate disease progression. Exposure to air pollution is one of the less studied and less investigated risk factors for COPD. Depending on the size and chemical nature of the pollutant, it can overcome the defence mechanism of the respiratory system and enter the lung tissues, thus causing some respiratory diseases. The World Health Organisation (WHO) reports that six major air pollutants have been identified, namely particulate matter (PM), ground-level ozone, carbon monoxide, sulphur dioxide, nitrogen dioxide and lead. The severe impact of PM exposure is demonstrated by the link between exposure to high concentrations of PM and certain severe diseases such as silicosis, lung cancer, cardiovascular disease and COPD. In Iași County, Romania, air quality measurements are performed by six automatic air quality monitoring stations, and the data obtained are used to create annual reports and these are also available online. Due to the high concentrations of air pollutants, the city of Iași is one of the three topmost polluted cities in Romania. A future assessment on the impact of air pollution on the health of the inhabitants of these cities and the implementation of new methods to improve air quality is needed.

Coronavirus diseases and pregnancy: COVID-19,SARS, and MERS

2020 ◽  
pp. 276-289
Author(s):  
Mobina Fathi ◽  
Kimia Vakili ◽  
Niloofar Deravi
Keyword(s):  
Pregnant Women ◽  
Intrauterine Growth Retardation ◽  
Negative Impact ◽  
World Health ◽  
Wuhan City ◽  
Intrauterine Growth ◽  
Exponential Increase ◽  
The World ◽  
Health Organization ◽  
Respiratory Droplets

Around the end of December 2019, a new beta-coronavirus from Wuhan City, Hubei Province, China began to spread rapidly. The new virus, called SARS-CoV-2, which could be transmitted through respiratory droplets, had a range of mild to severe symptoms, from simple cold in some cases to death in others. The disease caused by SARS-CoV-2 was named COVID-19 by WHO and has so far killed more people than SARS and MERS. Following the widespread global outbreak of COVID-19, with more than 132758 confirmed cases and 4955 deaths worldwide, the World Health Organization declared COVID-19 a pandemic disease in January 2020. Earlier studies on viral pneumonia epidemics has shown that pregnant women are at greater risk than others. During pregnancy, the pregnant woman is more prone to infectious diseases. Research on both SARS-CoV and MERS-CoV, which are pathologically similar to SARS-CoV-2, has shown that being infected with these viruses during pregnancy increases the risk of maternal death, stillbirth, intrauterine growth retardation and, preterm delivery. With the exponential increase in cases of COVID-19 throughout the world, there is a need to understand the effects of SARS-CoV-2 on the health of pregnant women, through extrapolation of earlier studies that have been conducted on pregnant women infected with SARS-CoV, and MERS-CoV. There is an urgent need to understand the chance of vertical transmission of SARS-CoV-2 from mother to fetus and the possibility of the virus crossing the placental barrier. Additionally, since some viral diseases and antiviral drugs may have a negative impact on the mother and fetus, in which case, pregnant women need special attention for the prevention, diagnosis, and treatment of COVID-19.

HIPEREMESIS GRAVIDARUM PADA IBU HAMIL DI KLINIK BIDAN SUPRIYATI SRIBIT BERBAH SLEMAN

2019 ◽  
Vol 14 (1) ◽  
pp. 51
Author(s):  
Pramukti Dian Setianingrum ◽  
Farah Irmania Tsani
Keyword(s):  
Blood Pressure ◽  
Pregnant Women ◽  
Hyperemesis Gravidarum ◽  
Unwanted Pregnancy ◽  
The Body ◽  
Nausea And Vomiting ◽  
Daily Activities ◽  
World Health ◽  
The World

Backgroud: The World Health Organization (WHO) explained that the number of Hyperemesis Gravidarum cases reached 12.5% of the total number of pregnancies in the world and the results of the Demographic Survey conducted in 2007, stated that 26% of women with live births experienced complications. The results of the observations conducted at the Midwife Supriyati Clinic found that pregnant women with hyperemesis gravidarum, with a comparison of 10 pregnant women who examined their contents there were about 4 pregnant women who complained of excessive nausea and vomiting. Objective: to determine the hyperemesis Gravidarum of pregnant mother in clinic. Methods: This study used Qualitative research methods by using a case study approach (Case Study.) Result: The description of excessive nausea of vomiting in women with Hipermemsis Gravidarum is continuous nausea and vomiting more than 10 times in one day, no appetite or vomiting when fed, the body feels weak, blood pressure decreases until the body weight decreases and interferes with daily activities days The factors that influence the occurrence of Hyperemesis Gravidarum are Hormonal, Diet, Unwanted Pregnancy, and psychology, primigravida does not affect the occurrence of Hyperemesis Gravidarum. Conclusion: Mothers who experience Hyperemesis Gravidarum feel nausea vomiting continuously more than 10 times in one day, no appetite or vomiting when fed, the body feels weak, blood pressure decreases until the weight decreases and interferes with daily activities, it is because there are several factors, namely, hormonal actors, diet, unwanted pregnancy, and psychology.

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