scholarly journals Prevalence of Vitamin D Deficiency among Patients of Acute Coronary Syndrome in a Tertiary Care Center of Eastern Nepal

2021 ◽  
Vol 59 (235) ◽  
Author(s):  
Richa Nepal ◽  
Prahlad Karki ◽  
Surendra Uraw ◽  
Madhab Lamsal

Introduction: Vitamin D deficiency is an emerging risk factor for cardiovascular diseases. Very few studies have been done to find out vitamin D deficiency status among cardiovascular patients in Nepalese setup. This research aims to find out the prevalence of vitamin D deficiency among patients of acute coronary syndrome admitted in a tertiary care center of eastern Nepal. Methods: This was a descriptive cross-sectional study conducted among patients of acute coronary syndrome admitted in a tertiary care hospital from 1st February 2018 to 31st July 2018. Ethical clearence was taken from Institutional Review Committee of B.P. Koirala Institute of Health Sciences (Reference number: 259/074/075-IRC). Convenience sampling method was used. Data was entered in Microsoft Excel and analyzed using Statistical Package for the Social Sciences version 25. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: A total of 33 (64.7%) at 95% Confidence Interval (51.58-77.82) patients of acute coronary syndrome had vitamin D deficiency in our study with 19 (37.3%) having mild deficiency and 14 (27.4%) having moderate deficiency. None of the patients had severe vitamin D deficiency in our study. The mean vitamin D levels were lower in diabetics (23.57±9.28ng/ml) as compared to non-diabetics (31.91±12.50ng/ml), in hypertensive patients (24.36±7.67ng/ml) as compared to non-hypertensive patients (30.97±13.72ng/ml), and in patients with dyslipidemia (22.86±6.44ng/ml) as compared to those without dyslipidemia (37.68±13.15ng/ml). Conclusions: Prevalence of vitamin D deficiency among patients of acute coronary syndrome in our study was comparable to various other homologous international studies.

2017 ◽  
Vol 6 (04) ◽  
pp. 282-285
Author(s):  
Shilpa Patil ◽  
Piyush Prajapati ◽  
Saurabh Gandhi ◽  
Ajinkya Bahulekar ◽  
Yash Pandey ◽  
...  

2021 ◽  
Vol 9 (02) ◽  
pp. 45-49
Author(s):  
Shyam Prasad Kafle ◽  
Eqtedar Ahmad ◽  
Lalan Prasad Rauniyar ◽  
Namu Koirala

INTRODUCTION: Vitamin D deficiency (VDD) is exceedingly predominant in children leading to dysregulation of the immune system and inflammation. Data on the prevalence of VDD in children with sepsis and its association with sepsis severity are limited from our part of the world. The primary aim of this study was to identify the burden of VDD in children with sepsis. MATERIAL AND METHODS: One hundred and five children (< 15 years) with sepsis were enrolled from April 15, 2017 to April 14, 2018 from a tertiary care center in Eastern Nepal. Demographic data including BMI, sequential organ failure assessment (SOFA) scores were recorded at the time of admission. Plasma 25-hydroxy vitamin D [25(OH)D] levels were measured by chemiluminescence immunoassay technique (CLIA) (MAGLUMI 25-OH Vitamin D; CLIA) within 24 hours of admission. Vitamin D concentrations of <20 ng/mL (50 nmol/L) were considered as deficient. RESULTS: Of the 105 children enrolled, the majority 74 (70.55%) had vitamin D deficiency. Vitamin D was deficient in 77, 65, and 66% of children in 1-5, 5-10, and 10-15 years of age group respectively. Vitamin D deficiency was maximum (80%) in underweight children. In the VDD group, 60% had severe sepsis, whereas only 32% had severe sepsis in vitamin D sufficient group with significant statistical association with sepsis severity and vitamin D deficiency. CONCLUSION: A high burden of VDD is present in children with sepsis which was found to be associated with greater severity of illness.


2021 ◽  
Vol 59 (240) ◽  
Author(s):  
Chandra Kala Rai ◽  
Sarbada Makaju

Introduction: Today’s generation is facing an increased prevalence of overweight and obesity. It may be genetic or habitual due to overeating of junk foods and sedentary lifestyle. It directly affects an individual personality and health. The main aim of this study is to find out the prevalence of overweight among medical students in a tertiary care center. Methods: This is a descriptive cross-sectional study done in 385 students in a tertiary care hospital from 25th January 2020 to 28th February 2021. The sample was collected by simple random sampling method after the approval from the Institutional Review Committee of Kathmandu Medical College and Teaching Hospital. Height in meter and weight in kilogram of students were measured to calculate body mass index. Data were analyzed by using Statistical Package of Social Science software version 16. Point estimate at 95% confidence interval was calculated along with frequency and proportion for binary data. Results: Among 385 students, 75 (19.48%) (95% Confidence Interval= 15.53%-23.44%) were overweight. Fifty-seven (14.85%) males and 18 (4.69%) females were overweight respectively. In total, there were 197 (51.01%) males and 188 (48.99%) females. Conclusions: The current study shows the prevalence of overweight among medical students is slightly higher than in studies done in similar settings.


2009 ◽  
Vol 48 (173) ◽  
Author(s):  
Pramod Acharya ◽  
RR Adhikari ◽  
J Bhattarai ◽  
NR Shrestha

INTRODUCTION:The time of presentation of acute coronary syndrome from the onset of chest pain determines the treatment modality and prognosis. Delayed presentation is associated with a poor outcome. In the present study, we tried to find out the causes of late presentation of ACS in a tertiary care center in the eastern part of Nepal.METHODS:It was a cross-sectional descriptive study that included 100 consecutive patients with ACS presenting to our institute over a period of 8 months. They were studied for their demographic profile, delay in presentation, the management done at the local centers and their final diagnosis.RESULTS:We found that patients living within Dharan City reached BPKIHS within 20 hours of the onset of chest pain while those from outside the city who came directly reached within 63 hours. Other patients reached their respective local centers (health posts, district hospitals and private clinics) within 39 hours. The commonest cause of delay was vehicular problem followed by unnecessary delay at the local centers. The work up for chest pain was inadequate in these centers. Late presentation to our institute significantly affected the optimal management.CONCLUSIONS: We found that significant number of patients with ACS from eastern Nepal presented late in our tertiary care center. In order to improve ACS outcome in this region, we advise equipping the local centers with electrocardiogram machines, improvement in ambulance services and a greater emphasis on coronary artery disease awareness programs as well as initiating preventive measures.KEY WORDS:acute coronary syndrome, chest pain, delayed presentation, electrocardiogram


2012 ◽  
Vol 109 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Jennifer R. Shiu ◽  
Glen J. Pearson ◽  
Theresa L. Charrois ◽  
Gabor Gyenes ◽  
Sheri L. Koshman

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