scholarly journals PENGARUH SENAM NIFAS DAN PIJAT OKSITOSIN TERHADAP INVOLUSI UTERI PADA IBU POSTPARTUM

2020 ◽  
Vol 5 (2) ◽  
pp. 65
Author(s):  
Inge Anggi Anggarini
Keyword(s):  
Maternal Mortality ◽  
Recovery Period ◽  
Control Group ◽  
Positive Contribution ◽  
Control Group Design ◽  
Mortality And Morbidity ◽  
Group Design ◽  
Uterine Involution ◽  
Post Test ◽  
Postpartum Mothers

Salah satu indikator untuk menentukan derajat kesehatan suatu bangsa ditandai dengan tinggi rendahnya angka kematian ibu. Hal ini merupakan suatu fenomena yang mempunyai pengaruh besar terhadap keberhasilan pembangunan kesehatan. Masa Nifas merupakan hal penting untuk diperhatikan guna menurunkan angka kematian ibu. Setelah persalinan tubuh seorang ibu memasuki masa pemulihan, salah satunya adalah involusi uteri yang dimulai segera setelah persalinan dan proses ini harus tuntas setelah 6 minggu.. Ada beberapa upaya yang dapat dilakukan untuk mempercepat proses involus uteri antara lain senam nifas dan pijat oksitosin. Tujuan Penelitian: menganalisis pengaruh kombinasi dari senam nifas dan pijat oksitosin terhadap involusi uteri pada ibu postpartum. Metode Penelitian: Penelitian ini merupakan penelitian quasi eksperimen dengan post test-only control group design. Pengambilan sampel dilakukan secara consecutive sampling.Hasil: Hasil penelitian menunjukkan terdapat perbedaan rerata yang bermakna pada penurunan tinggi fundus uteri antara kelompok perlakuan dan kelompok kontrol (p<0,05). Simpulan:Hasil penelitian ini diharapkan memberikan kontribusi positif terhadap ilmu kebidanan sebagai salah satu upaya nonfarmakologik untuk mempercepat proses involusi uteri sehingga dapat mengurangi perdarahan pada ibu postpartum yang sering terjadi pada masa postpartum karena proses involusi yang tidak berjalan normal (sub involusi uteri) dan dapat mendukung upaya pemerintah dalam mengurangi angka mortalitas dan morbiditas ibu.An indicator to determine the degree of health, high and low maternal mortality rates characterize a nation. It is a phenomenon that has great importance to the increasing success of health development. The puerperium is a crucial thing to consider to reduce maternal mortality. After delivery, the mother's body begins the recovery period, one of which is uterine involution which starts immediately after delivery, and this process completed after six weeks. Read more about the process of returning the uterus to the state before pregnancy after giving birth. This process is critical because puerperal bleeding can occur sooner or later. Several efforts can make to improve the process of uterine involves, including puerperal exercises and oxytocin massage. The aims:  to analyze the effect the combination of puerperal exercises and oxytocin massage on uterine involution in postpartum mothers The Method: This research is a quasi-experimental study with post-test only control group design. Sampling has taken as consecutive sampling. The Results: The results showed that there were significant mean differences in the decrease in the height of the fundus between the treatment group and the control group (p <0.05). The conclusion: The results of this study expected to make a positive contribution to midwifery as one of the non-pharmacological efforts to accelerate the process of uterine involution to reduce bleeding in postpartum mothers that often occurs during the postpartum because of involution processes that are not running normally (sub involution uteri) and can support government efforts in reducing maternal mortality and morbidity.

scholarly journals Pengaruh PemberianTablet Besi Pada Ibu Nifas Terhadap Anemia Post Partum Di Wilayah Puskesmas Pegandon

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Sri Rahayu
Keyword(s):  
Pregnant Women ◽  
Post Partum ◽  
Reproductive Age ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Kolmogorov Smirnov ◽  
Postpartum Mothers ◽  
Test Control

Abtrak. Anemia merupakan masalah kesehatan masyarakat secara global baik dinegara berkembang maupun negara maju. Anemia terjadi pada semua tahap siklus kehidupan, umumnya terjadi pada masa anak-anak dan wanita hamil (WHO, 2008). Di puskesmas Pegandon Kabupaten Kendal pada bulan Agustus 2017 didapatkan ibu hamil dengan kadar HB 8,2 gr% mengalami perdarahan pada saat melahirkan. Penelitian ini bertujuan mengevaluasi pemberian tablet FEpada ibu nifas.Desain penelitian menggunakanmatching pretest-post test control group design. Penelitian ini menggunakan data kohort dari ibu hamil  di puskesmas Pegandon yang melahirkan pada bulan Desember 2017 – Januari 2018. Sampelnya ibu nifas pada bulan  Januari – Maret 2018yang datang di puskesmas Pegandon untuk melahirkan sebanyak 72 ibu nifas. Hasil penelitian menunjukkan sebagian besar  pada responden perlakuan mempunyai usia reproduksi 30 (83,3%),  sebagian berpendidikan (SD danSMP) 28 (77.8%) dan berpenghasilan sesuai UMK 22 (61.1%) sedangkan pada responden control untuk usia reproduksi25 (69%), berpendidikan (SD dan SMP) 31 (86%) dan berpenghasilan sesuai UMK 15 (41.7%).Pada analisis bivariate dengan uji kolmogorov-smirnov didapatkan p> 0.00 pada perlakuan dan kontrol. Disimpulkan bahwa diberikan dan tidak diberikan tablet FE pada ibu nifas didapatkan hasil sama berpengaruh dalam peningkatan kadar HB.Disarankansetiap ibu nifas meminum tablet FE supaya tidak terjadi anemia dan memberikan ASI pada bayinya dengan maksimal.Kata kunci : anemia, ibu nifas, tablet FE The Influence Of Iron Tablets In Pifandon Mother To Post Partum Anemia In Pegandon Community Health Center Area Abtract.Anemia is a global public health problem both in developing and developed countries. Anemia occurs at all stages of the life cycle, generally occurring during childhood and pregnant women (WHO, 2008). In Pegandon Puskesmas Kendal Regency in August 2017 it was found that pregnant women with HB levels 8.2 gr% had bleeding at the time of delivery. This study aims to evaluate the administration of FE tablets to postpartum mothers. The study design used a matching pretest-post test control group design. This study uses cohort data from pregnant women at the Pegandon puskesmas who gave birth in December 2017 - January 2018. The sample was postpartum mothers in January - March 2018 who came to the Pegandon puskesmas to deliver 72 postpartum mothers. The results showed that most of the treatment respondents had a reproductive age of 30 (83.3%), some were educated (SD and SMP) 28 (77.8%) and earning according to MSE was 22 (61.1%) while the control respondents were for reproductive age 25 (69% ), educated (elementary and junior high) 31 (86%) and earning according to UMK 15 (41.7%). In the bivariate analysis with the Kolmogorov-Smirnov test, p> 0.00 was obtained for treatment and control. It was concluded that given and not given FE tablets to the puerperal mothers found the same effect had an effect on increasing HB levels. It is recommended that every puerperal woman take FE tablets so that anemia does not occur and give milk to her baby to the maximum..Keywords: anemia, puerperal mothers, FE tablets

scholarly journals Pengaruh Senam Nifas terhadap Penurunan Tinggi Fundus Uteri pada Ibu Post Partum di RSUP DR. M. Djamil Padang

2014 ◽  
Vol 3 (3) ◽  
Author(s):  
Nurniati Tianastia Rullynil ◽  
Ermawati Ermawati ◽  
Lisma Evareny
Keyword(s):  
Uterine Contraction ◽  
Post Partum ◽  
Intervention Group ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
The Third ◽  
Uterine Involution ◽  
Maternal Morbidity And Mortality ◽  
Post Test

AbstrakPerdarahan merupakan penyebab utama kesakitan dan kematian ibu pada masa nifas, dimana 50%-60% karena kegagalan miometrium berkontraksi secara sempurna. Salah satu asuhan untuk memaksimalkan kontraksi uterus pada masa nifas adalah dengan melaksanakan senam nifas, guna mempercepat proses involusi uteri. Tujuan penelitian ini adalah untuk mengetahui pengaruh senam nifas terhadap penurunan tinggi fundus uteri (TFU) pada ibu post partum. Penelitian ini merupakan studi eksperimental dengan Post Test Only Control Group Design. Alat yang digunakan dalam penelitian berupa kaliper pelvimetri. Diberikan perlakuan senam nifas pada kelompok intervensi dan tidak senam nifas pada kelompok kontrol, kemudian dilakukan pengukuran tinggi fundus uteri hari ke-1, hari ke-3 dan hari ke-6. Data dianalisa menggunakan Uji General Linier Model (GLM). Rerata TFU hari ke-1 pada kelompok intervensi 12,37±0,72 dan 12,42±0,54 pada kelompok kontrol. Rerata TFU hari ke-3 pada kelompok intervensi 9,00±0,94 dan 9,87±0,75 pada kelompok kontrol. Sedangkan rerata TFU hari ke-6 pada kelompok intervensi 5,72±0,88 dan 7,37±0,68 pada kelompok kontrol. Terdapat perbedaan yang signifikan penurunan tinggi fundus uteri antara kedua kelompok pada hari ke-3 (p=0,00) dan hari ke 6 (p=0,00). Dari hasil penelitian dapat disimpulkan bahwa senam nifas berpengaruh terhadap penurunan tinggi fundus uteri. Penurunan tinggi fundus uteri pada kelompok intervensi lebih turun dibanding kelompok kontrol.Kata kunci: senam nifas, tinggi fundus uteri, post partumAbstractHemorrhage is a major cause of maternal morbidity and mortality in the puerperium, about 50%-60% of hemorrhage occurs due to failure of myometrium to contract completely. One care to maximaze uterine contraction during the puerperium is by implementing parturition gymnastics in order to accelarate the process of uterine involution. The purpose of this study was to determine the effect of parturition gymnastics on a decreasing of fundal height of maternal postpartum.This was experimental study with Post Test Only Control Group Design. The tool used in this study was pelvimetry caliper. Parturition gymnastics was given to intervention group but the control group did not treated with parturition gymnastics, then fundal height was measured on the first day, third day, and sixth day. Data were analyzed by using General Linear Model (GLM) test. Mean of fundal height on the first day on the intervention group was 12.37±0.72 and 12.42±0.54 on the control group. Mean of fundal height on the third day was 9.00±0.94 on the intervention group and 9.87±0.75 on the control group. Meanwhile, mean of fundal height on the sixth day on the intervention group was 5.72±0.88 and 7.37±0.68 on the control group. There was significant decrease of fundal height between the two groups on the third day 3 at (p=0.00) and the sixth day at (p=0.00). From the research results, it can be concluded that parturition gymnastic has an effect on the decreasing of fundal height. The decline of fundal height on the intervention group is more decreasing than that of on the control

scholarly journals Effectiveness of Early Exercise Against Uterine Involution in Spontaneous Postpartum Patients

2019 ◽  
Vol 15 (1) ◽  
pp. 15-21
Author(s):  
Dian Nurafifah ◽  
Dadang Kusbiantoro
Keyword(s):  
Treatment Group ◽  
Maternal Mortality ◽  
Control Group ◽  
P Value ◽  
Positive Contribution ◽  
Control Group Design ◽  
Early Exercise ◽  
Uterine Involution ◽  
Quasi Experimental ◽  
Group 2

It is estimated that 50% of puerperal mortality occur within the first 24 hours. At thistime the involution process occured. Involutionary disorders cause complications whichis the leading cause of maternal mortality. Most of postpartum women do not obtainexercise guidance after giving birth. They are only advised to do simple mobilizationwithout planned guidance. The purpose of this study was to determine the effectivenessof early exercise against uterine involution (fundus and lochea). The research methodused Quasi Experimental (pre-post test non equivalent control group design). It wasconducted from May to August 2017. The samples were 40 respondents spontaneousprimiparous postpartum mother. The study was started by 1) divided the samples intocontrol group and treatment group, 2) measured the fundus and lochea, 3) providedearly exercise on treatment group, 4) re-measured fundus and lochea in both groups, 5)analyzed the effectiveness of early exercise to fundus and lochea expenditure decrease.The data analysis used Mann Whitney with α = 0.05. The results showed p value is 0.000(fundus) and p value are 0.001 (lochea). It means that early exercise is effective againstuterine involution (fundus and lochea). The results can provide positive contribution inpreventing maternal mortality caused by puerperal complications.

scholarly journals Senam Nifas Memengaruhi Proses Involutio Uteri

2020 ◽  
Vol 2 (1) ◽  
pp. 1-6
Author(s):  
Hastuti Usman ◽  
Artika Dewie ◽  
Muthmainnah Ahsan
Keyword(s):  
Intervention Group ◽  
Sampling Technique ◽  
Statistical Test ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
Early Ambulation ◽  
Group Design ◽  
Uterine Involution ◽  
Postpartum Mothers

Postpartum mothers are afraid to do many movements. If mothers do early ambulation, it can facilitate the process of uterine involution. This research is aim to clear out the effect of puerperal gymnastic on the uterine involution process to postpartum mothers. It uses a quasi-experiment design and Pretest and posttest control group design. The sampling technique uses an accidental sampling technique. The instrument in this study is the observation sheet, leaflet, andgymnastics guide.Statistical test using the Mann Whitney test. Before performing puerperal gymnastic, the average of the Fundal Height (Tinggi Fundus Uteri) of the intervention group was 10.9 cm, and the average of Fundal Height of the control group was 10.9 cm. The statistical test obtained p-value=0.457, which means there is no difference in the average the Fundal Height between the intervention group and the control group. Whereas after childbirth exercise, the average of Fundal Height of the intervention group was 0.9 cm, and the average of  Fundal Height of the control group was 7.3 cm. Statistical test obtained p-value <0.001.To sum up, there is an effect of puerperal exercise on uterine involution speed. Suggestions for Puskesmas Kampung Baru, especially the midwives, are to provide postpartum gymnastics services for postpartum mothers to accelerate uterine involution.

scholarly journals The effectiveness of postpartum exercise to increase the quality of life score of postpartum mothers.

2021 ◽  
Vol 8 (1) ◽  
pp. 79-85
Author(s):  
Inge Anggi Anggarini
Keyword(s):  
Quality Of Life ◽  
Adjustment Process ◽  
Control Group ◽  
Positive Contribution ◽  
Control Group Design ◽  
Mortality And Morbidity ◽  
Life Score ◽  
Quasi Experimental ◽  
Postpartum Mothers

Pregnancy, childbirth and postpartum are dramatic episodes of the biological conditions, psychological changes and adaptations of a woman who has experienced them. Complex physical and emotional changes make a mother-to-be need adaptation to lifestyle adjustments related to pregnancy, childbirth and the postpartum period. The adjustment process may work but some may not work so that the mother-to-be can experience psychological disorders with various symptoms or syndromes. There are several efforts that can be made to improve the quality of life for postpartum mothers, including postpartum exercise. The aims: to analyze the effectiveness of postpartum exercise to increase the quality of life score of postpartum mothers. The Method: This study was a quasi-experimental study with a pre-posttest control group design. Sampling taken  by consecutive sampling. Results: The results showed that there were significant mean differences in the quality of life scores between the treatment group and the control group (p <0.05). Conclusion: The results of this study are expected to make a positive contribution to the science of midwifery as a non-pharmacological effort to improve the quality of life for postpartum mothers and to support government efforts to reduce maternal mortality and morbidity.

PENGGUNAAN MODEL PEMBELAJARAN STAD (STUDENT TEAMS-ACHIEVMENT DIVISIONS) DALAM PEMBELAJARAN MENULIS SURAT DINAS SISWA KELAS VIII DI SMP NEGERI SE-KECAMATAN PANYINGKIRAN KABUPATEN MAJALENGKA TAHUN AJARAN 2013/2014

2017 ◽  
Vol 3 (1) ◽  
pp. 447
Author(s):  
Iyay Robia Khoerudin ◽  
Neneng Titin ◽  
Eki Kiyamudin
Keyword(s):  
Random Sampling ◽  
Simple Random Sampling ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Student Teams ◽  
Post Test ◽  
Test Control

Penelitian ini bertujuan untuk mengetahui kemampuan menulis surat dinas siswa kelas VIII di SMP Negeri Se-Kecamatan Panyingkiran Kabupaten Majalengka, mengetahui kemampuan menulis surat dinas dengan menggunakan model pembelajaran STAD (Student Teams-Achievment Divisions) siswa kelas VIII di SMP Negeri Se-Kecamatan Panyingkiran Kabupaten Majalengka, serta menjelaskan efektifitas model pembelajaran STAD (Student Teams-Achievment Divisions) untuk meningkatkan  pengajaran menulis surat dinas siswa Kelas VIII di SMP Negeri Se-Kecamatan Panyingkiran Kabupaten Majalengka.Penelitian ini menggunakan pendekatan kuantitatif dan kualitatif dengan metode eksperimen Pre test-Post test Control Group Design, populasinya yaitu SMP Negeri Se-Kecamatan Panyingkiran Kabupaten Majalengka tahun ajaran 2013/2014, sedangkan  sampelnya ditentukan melalui teknik simple random sampling yaitu kelas VIII G SMP Negeri 2 Panyingkiran sebagai kelas eksperimen dan kelas VIII B SMP Negeri 1 Panyingkiran sebagai kelas kontrol. Instrumen pengumpulan data yang digunakan tes tertulis tes awal dan tes akhir, kuesioner, lembar observasi guru dan siswa, setelah data diperoleh maka dilakukan analisis data. Data kuesioner dan observasi dianalisis dalam bentuk uraian sedangkan data tes dianalisis dengan statistik dan di deskripsikan.Berdasarkan perhitungan statistik program SPSS 16.0 diperoleh hasil uji t pretes pada kedua kelas tersebut memiliki nilai t=5.429 derajat kebebasan (df)=n-1=38 nilai probability (sig 2-tailed) sebesar 0,000.  Hal ini berarti t hitung <0,005. Artinya 0,000<0,05, pada uji t ini bahwasanya pretes pada kedua kelas terdapat perbedaan yang signifikan antara kelas eksperimen dengan kelas kontrol.  Apabila ditinjau dari segi rata-rata pretes eksperimen lebih efektif daripada kelas kontrol. Hal ini terbukti dari rata-ratanya pretes kelas eksperimen 64,8 kelas kontrol 62,3 selisih rata-rata 2,5. Sedangkan rata-rata postes kelas eksperimen 81,2 dan kelas kontrol 69 terjadi selisih postes 12,2.

ANALISIS KEMAMPUAN PROBLEM POSING MATEMATIS SISWA DALAM PEMBELAJARAN MODEL KOOPERATIF NHT

2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Kadir Kadir ◽  
Munawir Sadzali
Keyword(s):  
Random Sampling ◽  
Problem Posing ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Cluster Random Sampling

Tujuan dari penelitian ini adalah menganalisis pengaruh model pembelajaran kooperatif tipe Number Head Together (NHT) terhadap keterampilan problem posing matematis siswa. Penelitian ini dilakukan di SD Al- Zahra Indonesia, untuk tahun akademik 2014/2015. Metode yang digunakan dalam penelitian ini adalah metode kuasi eksperimen dengan Post-test Only Control Group Design, melibatkan 60 siswa sebagai sampel. Untuk menentukan sampel digunakan teknik cluster random sampling. Pengambilan data menggunakan instrumen seperti tes esai tertulis. Keterampilan problem posing matematis siswa yang mengajar dengan model pembelajaran kooperatif tipe Number Head Together (NHT) lebih tinggi daripada keterampilan problem posing matematis siswa yang diajarkan dengan model pembelajaran klasik (t hitung = 2,01 table t tabel = 2,00 ). Persentase jawaban siswa dari problem posing berdasarkan gambar, tabel dan diagram yang diajarkan dengan model pembelajaran kooperatif tipe Number Head Together (NHT) lebih tinggi daripada siswa yang mengajar dengan model pembelajaran klasik. Kesimpulan hasil penelitian ini bahwa pembelajaran matematika Pecahan dengan model pembelajaran kooperatif tipe Number Head Together (NHT) memiliki pengaruh yang signifikan terhadap keterampilan problem posing matematika siswa.

The Effect of Anonymous Peer Assessment on Writing Ability of the Eleventh Grade Students at SMK PGRI 1 Singaraja

2018 ◽  
Vol 2 (1) ◽  
pp. 1
Author(s):  
A.P. Adhiyanti ◽  
A.A.I.N Marhaeni ◽  
I.P.I Kusuma
Keyword(s):  
Peer Assessment ◽  
Lesson Plan ◽  
Control Group ◽  
Control Group Design ◽  
Writing Ability ◽  
Group Design ◽  
Writing Test ◽  
Post Test ◽  
The Mean ◽  
Academic Year

  This study aimed to investigate the effect of anonymous peer assessment on students’ writing ability. Quantitative approach was used in this study. Post-test only control group design was the design used in this experimental study. The post-test only control group design was designed to discover the purpose of this study which was to investigate the significant effect on writing ability between students who obtain feedback from anonymous peer assessment and students who obtain feedback from conventional assessment. The study was conducted at SMK PGRI 1 Singaraja. The eleventh grade students in Academic Year 2017/2018 were chosen as the population. The samples were 44 students from XI AP and XI UPW. The instruments used in this study were lesson plan, anonymous peer checklist, writing scoring rubric, and writing test. Writing scoring rubric and writing test were used to obtain the data through post-test while lesson plan and anonymous peer assessment were used during the treatment. The data then was analyzed by using SPSS 16. The results of the analysis show that (1) the mean score of the experimental group was 77.55 while the mean score of the control group was 68.77. (2) The t-observe was 3.892 and it exceeded the t-critical value which was 2.018. Therefore, based on the aforementioned results, it can be concluded that there was a significant difference on writing ability between the eleventh grade students who obtained feedback from anonymous peer assessment and those who obtained feedback from conventional assessment at SMK PGRI 1 Singaraja in academic year 2017/2018. 

PENINGKATAN KEMAMPUAN PEMAHAMAN DAN KREATIVITAS MATEMATIS SISWA DENGAN MENGGUNAKAN MODEL PENCAPAIAN KONSEP

2013 ◽  
Vol 19 (1) ◽  
pp. 52
Author(s):  
Adi Suarman Situmorang
Keyword(s):  
Random Sampling ◽  
Control Group ◽  
P Value ◽  
Design Data ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Test Control

Abstract Tujuan penelitian bertujuan untuk mengetahui peningkatan kemampuan kreativitas matematika siswa yang diajar dengan model pencapaian konsep lebih tinggi dari siswa yang diajar dengan pembelajaran konvensional. Mengetahui interaksi antara model pembelajaran pencapaian konsep dengan tingkat kemampuan matematika siswa terhadap peningkatan kemampuan kreativitas matematika siswa. Penelitian ini dilaksanakan di SMA Negeri 5 Medan dengan jumlah sampel sebanyak 80 siswa dari 364 siswa SMA kelas X melalui teknik random sampling, Penelitian ini merupakan suatu studi eksperimen dengan desain penelitian pre-test-post-test control group design. Data diperoleh melalui nilai semester untuk kemampuan awal matematis (KAM), tes kemampuan pemahaman matematis, tes kemampuan kreativitas matematis. Data dianalisis dengan uji ANAVA dua jalur. Hasil analisis data menunjukkan bahwa rata-rata tes kemampuan kreativitas eksperimen dan kontrol adalah 13,3 dan 7,58 dengan p-value (2-tailed) adalah 0, dengan 0 < α = 0,05 maka terdapat perbedaan kemampuan kreativitas matematik siswa yang diajarkan dengan Model Pencapaian Konsep (MPK) dan Pendekatan Pembelajaran Konvensional, nilai signifikan sebesar 0,732, karena 0,732 > 0,05 maka tidak ada interaksi antara pendekatan pembelajaran dengan kemampuan awal siswa terhadap perbedaan kemampuan kreativitas matematik siswa. .

PENGARUH EKSTRAK SAMBILOTO (Andrographis paniculata [Burm f..] Ness) TERHADAP HITUNG EOSINOFIL MENCIT MODEL ALERGI INFLAMASI

2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Arisanty Nursetia R
Keyword(s):  
Andrographis Paniculata ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Per Oral

Sambiloto mengandung flavonoid dan andrografolid yang mempunyai efek anti alergi. Penelitian ini bertujuan untuk mengetahui Pengaruh Ekstrak Sambiloto (Andrographis paniculata [Burm f.] Ness) terhadap hitung Eosinofil Serum Mencit Model Alergi Inflamasi. Jenis penelitian ini adalah eksperimental laboratorik, dengan post test only control group design. Hewan uji berupa 15 ekor mencit jantan. Mencit dibagi menjadi tiga kelompok, masing-masing terdiri dari 5 ekor. Kelompok I (kontrol) hanya diberi diet standar. Kelompok II diberi diet standar dan ekstrak sambiloto per oral dengan dosis 10mg/20 gram BB/hari. Kelompok III diberi diet standar dan antihistamin per-oral dengan dosis 0,4 mg/20 gram BB/hari. Sensitisasi mencit dengan ovalbumin (OVA). Hari ke-4 dan ke-20 dipapar OVA i.p. Dosis 0,15 cc/mencit. OVA inhalasi ke-37 secara intraorbital. Analisis data dengan uji Anova menggunakan program SPSS for Windows Release 11.5. Hasil penelitian menunjukkan rata-rata eosinofil mencit kelompok I = 0,94% kelompok II = 0,87% dan kelompok III = 1,2%. Dengan analisa statistik kelompok II dibandingkan kelompok I, kelompok III dibandingkan kelompok I dan kelompok II dibanding kelompok III menunjukkan perbedaan hitung eosinofil yang tidak bermakna (p>0,05). Ekstrak sambiloto dengan dosis 10 mg/20gram BB/hari dapat menurunkan hitung eosinofil serum pada mencit model alergi inflasi.

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