Habitual Physical Activity in Patients with Myasthenia Gravis Assessed by Accelerometry and Questionnaire

Background: Physical activity (PA) in patients with myasthenia gravis (MG) is considered safe and beneficial, and an active lifestyle is required to obtain the health benefits of exercise. However, as the disease leads to physical impairments an insight into the overall PA habits in this patient population is relevant but lacking. Objective: To measure habitual physical activity in a Danish cohort of patients with MG measured by accelerometer and questionnaire, and to determine relevant predictors for PA intensities. Methods: Habitual physical activity was assessed by; 1) the accelerometer Acti Graph in a cohort of patients recruited from our neuromuscular clinic, 2) the International Physical Activity Questionnaire (IPAQ) in a web-based survey. PA levels were compared to international recommendations. Predictors for PA (age, sex, body mass index, disease severity and duration) were included in the regression analyses. Results: Habitual physical activity was measured by accelerometer for 7 days in 69 patients and by questionnaire in 691 patients. Measured by the accelerometer, 46%of the patients did not meet the international recommendations for PA at moderate/vigorous intensity and 57%were below the recommendations for steps per day. Measured by the IPAQ, 48%did not meet the recommendations. Disease severity and age were predictors for PA intensities. Conclusions: This study found that around half of the included patients did not meet the recommendations for PA. This is a concern, as it increases the risk of life-style related diseases. Disease severity and age may be taking into consideration when counseling the patients about PA.

Objective and Self-reported Assessment of Physical Activity of Women over 60 Years Old

Ageing International ◽

10.1007/s12126-021-09423-z ◽

2021 ◽

Author(s):

Anna Ogonowska-Slodownik ◽

Natalia Morgulec-Adamowicz ◽

Paula Richley Geigle ◽

Malgorzata Kalbarczyk ◽

Andrzej Kosmol

Keyword(s):

Physical Activity ◽

Age Groups ◽

Subjective Assessment ◽

The Self ◽

Short Version ◽

Objective Data ◽

Steps Per Day ◽

Assessment Measures ◽

AbstractThe aim of the study was to examine changes in objective and self-reported physical activity (PA) among women aged 60 years and older. The study included 200 women aged over 60 years, divided into three groups according to age (60–65 years, 66–70 years, > 70 years). The subjective assessment was provided with the International Physical Activity Questionnaire (IPAQ) – short version with self-reported PA assessment, and objective data was provided by an Actigraph GT3-BT worn for seven days. Significant differences in moderate and high intensity PA, moderate-to-vigorous PA and steps per day were found between the oldest and youngest groups; as well as in low, moderate, moderate-to-vigorous PA and steps per day between groups middle and oldest. In all three age groups, 1) significant differences were observed between subjective and objective measurements of physical activity and 2) no correlation was found between assessment measures. It was found that only direct PA measurement declined with age in women over 60 years old, and that sedentary behavior is underestimated, and moderate and vigorous PA overestimated, with the self-reported IPAQ.

Misreporting of Physical Activity and Sedentary Behavior in Parents-to-Be: A Validation Study across Sex

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18094654 ◽

2021 ◽

Vol 18 (9) ◽

pp. 4654

Author(s):

Tom Deliens ◽

Vickà Versele ◽

Jasper Jehin ◽

Eva D’Hondt ◽

Yanni Verhavert ◽

...

Keyword(s):

Physical Activity ◽

Sedentary Behavior ◽

Moderate Intensity ◽

Strong Correlations ◽

Self Reports ◽

Vigorous Intensity ◽

Context Specific ◽

Acceptable Agreement ◽

This study validated the International Physical Activity Questionnaire (IPAQ) and the Context-specific Sedentary Behavior Questionnaire (CSBQ) against accelerometry among parents-to-be. Sex-differences in potential misreporting of physical activity (PA) and sedentary behavior (SB) were also investigated. Self-reported total PA (TPA), light-intensity PA (LPA), moderate-intensity PA (MPA), vigorous-intensity PA (VPA), moderate-to-vigorous-intensity PA (MVPA), and SB of 91 parents-to-be (41 men and 50 women) were compared with Actigraph data according to sex. Furthermore, the extent of misreporting was compared between sexes. Strong correlations for TPA and weak-to-moderate correlations for LPA, MPA, VPA, MVPA, and SB were observed. Participants underestimated TPA by 1068 min/week (=17.8 h/week; −50%), LPA by 1593 min/week (=26.6 h/week; −83%), and SB by 428 min/week (=7.1 h/week; −11%) and overestimated MPA by 384 min/week (=6.4 h/week; +176%) and MVPA by 525 min/week (=8.8 h/week; +224%). Males overreported VPA more than females in absolute minutes per week (238 min/week, i.e., 4.0 h/week vs. 62 min/week, i.e., 1.0 h/week), whereas, in relative terms, the opposite (+850% vs. +1033%) was true. The IPAQ and CSBQ can be used with caution to estimate TPA and SB among parents-to-be considering a strong correlation but low agreement for TPA and a weak-to-moderate correlation but acceptable agreement for SB. We disadvise using these self-reports to estimate PA on the distinct intensity levels.

Objectively Measured Sedentary Behavior and Physical Activity Across 3 Trimesters of Pregnancy: The Monitoring Movement and Health Study

Journal of Physical Activity and Health ◽

10.1123/jpah.2020-0398 ◽

2020 ◽

pp. 1-8

Author(s):

Bethany Barone Gibbs ◽

Melissa A. Jones ◽

John M. Jakicic ◽

Arun Jeyabalan ◽

Kara M. Whitaker ◽

...

Keyword(s):

Physical Activity ◽

Pregnancy Outcomes ◽

Second Trimester ◽

Gestational Weight ◽

Excessive Gestational Weight Gain ◽

Steps Per Day ◽

Vigorous Intensity ◽

Adverse Pregnancy ◽

Objectively Measured

Background: Though moderate- to vigorous-intensity physical activity is recommended, limited research exists on sedentary behavior (SED) during pregnancy. Methods: The authors conducted a prospective cohort study to describe objectively measured patterns of SED and activity during each trimester of pregnancy. Women wore thigh- (activPAL3) and waist-mounted (ActiGraph GT3X) activity monitors. SED and activity were compared across trimesters using likelihood ratio tests and described using group-based trajectories. Exploratory analyses associated SED and activity trajectories with adverse pregnancy outcomes and excessive gestational weight gain. Results: Pregnant women (n = 105; mean [SD] age = 31 [5] y; prepregnancy body mass index = 26.2 [6.6] kg/m2) had mean SED of 9.7, 9.5, and 9.5 hours per day (P = .062) across trimesters, respectively. Some activities differed across trimesters: standing (increased, P = .01), stepping (highest in second trimester, P = .04), steps per day (highest in second trimester, P = .008), and moderate- to vigorous-intensity physical activity (decreased, P < .001). Prolonged SED (bouts ≥ 30 min) and bouted moderate- to vigorous-intensity physical activity (≥10 min) were stable (P > .05). In exploratory analyses, higher SED and lower standing, stepping, and steps per day trajectories were associated with increased odds of adverse pregnancy outcomes (P < .05). No trajectories were associated with excessive gestational weight gain. Conclusions: Pregnant women exhibited stable SED of nearly 10 hours per day across pregnancy. Future research evaluating SED across pregnancy and adverse pregnancy outcome risk is warranted.

The association of innate and acquired aerobic capacity with resilience in healthy adults: Protocol for an eight-week randomized controlled web-based physical exercise intervention study (Preprint)

10.2196/preprints.29712 ◽

2021 ◽

Author(s):

David Tobias Ochmann ◽

Keito F A Philippi ◽

Peter Zeier ◽

Magdalena Sandner ◽

Barlo Hillen ◽

...

Keyword(s):

Physical Activity ◽

Physical Exercise ◽

Aerobic Capacity ◽

Exercise Intervention ◽

Intervention Group ◽

Control Group ◽

Active Lifestyle ◽

Web Based ◽

Before And After ◽

Physically Inactive

BACKGROUND Physical activity ameliorates chronic stress. Latest research suggests a relation between resilience and physical fitness. Beneficial adaptations of the hypothalamic-pituitary-adrenal axis, the sympathetic nervous system, the endocannabinoid system, and the tryptophan pathway, induced by an active lifestyle, are considered to be resilience conducive. However, detailed knowledge on the molecular link between the effects of acute and chronic physical exercise and an improved resilience is missing. OBJECTIVE Therefore, we implement a human exercise intervention trial addressing the main hypotheses: (1) web-based exercise training improves aerobic capacity of physically inactive adults, which (2) is accompanied by improved resilience. In this setting, we will analyze the relation of resilience parameters with innate and acquired aerobic capacity as well as circulating signaling molecules. METHODS 70 healthy physically inactive (<150min/week physical activity) adults (18-45y) will be randomly assigned to an intervention or control group. Participants in the intervention group receive weekly training utilizing progressive endurance and interval running individually adapted to their training performance via web-based physician support. A standardized incremental treadmill exercise test is performed before and after the intervention period of eight weeks to determine innate and acquired aerobic capacity. Before and after the intervention psychological tests and questionnaires that characterize parameters implicated in resilience (including impulse control, working memory, stress coping, emotion regulation) will be applied. Blood, and saliva will be sampled for analysis of lactate, cortisol, endocannabinoids, catecholamines, kynurenic acid, cell-free DNA and further circulating signal transducers. Statistical analysis will provide comprehensive knowledge on the relation of aerobic capacity and resilience, and furthermore, the capacity of peripheral factors to mediate the promoting effects of exercise on resilience. RESULTS The study was registered in October 2019. Enrollment began in September 2019. Out of 161 subjects, who were initially screened via telefon survey, 43 fulfilled the inclusion criteria and were included. Among the 17 participants in the intervention group, and 14 participants in the control group, who completed the study (total 31), no serious adverse event has been reported. Four participants withdrew during the programm (individual reasons), and 8 participants have not yet completed or begun the program due to the Covid-19 pandemic. Enrollment and data analysis are ongoing, and results are expected to be submitted for publication in October 2021. CONCLUSIONS Our study aims to demonstrate that an increase in physical activity with a simultaneous improvement in aerobic capacity is associated with an increase in resilience. This study design allows to investigate the effect of an active lifestyle on circulating molecular marker levels and their relationship to resilience factors. This will offer novel approaches for the diagnosis of depression and the therapy by exercise prescription. CLINICALTRIAL DRKS00018078, registered October 02, 2019, German Clinical Trials Register. Retrospectively registered: First participant September 10, 2019.

Abstract P063: The Association Between Physical Activity and Fasting and 2-Hour Glucose in US Adults: NHANES 2013-2014

Circulation ◽

10.1161/circ.137.suppl_1.p063 ◽

2018 ◽

Vol 137 (suppl_1) ◽

Author(s):

Joshua R Sparks ◽

Xuewen F Wang

Keyword(s):

Physical Activity ◽

Heart Rate ◽

Plasma Glucose ◽

Fasting Glucose ◽

Glucose Disposal ◽

Moderate Intensity ◽

Moderate Intensity Physical Activity ◽

Vigorous Intensity ◽

Background: Glucose concentrations in a fasted and during a glucose challenged state rely on different mechanisms for regulation. In a fasted state, hepatic regulation of glucose is important; while in a glucose challenged state, muscle glucose disposal becomes more important. Evidence suggests that physical activity of moderate or higher intensities can increase muscle glucose disposal during an insulin-stimulated state, but has less effect on hepatic insulin sensitivity. The purpose of this study was to examine the associations between glucose concentrations (fasting and after an oral glucose ingestion) and minutes of physical activity at moderate- and vigorous-intensity in a large population. Methods: The sample included 2,807 adults (47.4% male and 52.6% female) aged 18-80 years who participated in the National Health and Nutritional Examination Surveys (NHANES) from 2013-2014 and who did not take any diabetic medications. Minutes being physically active at moderate- and vigorous-intensities during work, and recreationally, were collected using the Physical Activity Questionnaire, which was based on the Global Physical Activity Questionnaire. Moderate-intensity physical activity was defined as any activity that caused a small increase in breathing or heart rate, while vigorous-intensity physical activity was defined as large increases in breathing or heart rate. Both intensities had to be performed for a minimum of 10 continuous minutes. Plasma glucose concentrations at fasting and 2 hours after consumption of a drink containing 75g glucose (2-hour glucose) were determined. Pearson product correlations were performed for analysis. Results: The population had 141±133 (mean±SD) minutes of moderate-intensity physical activity during work and 63±56 minutes recreationally, as well as 174±156 minutes of vigorous-intensity physical activity during work and 77±56 minutes recreationally. Minutes of vigorous-intensity physical activity performed during work was associated with 2-hour plasma glucose concentrations (r=0.15; p=0.045); this association was not affected after adjusting for age, race, and sex (p=0.049), but was no longer significant after BMI was also adjusted (p=0.059). Recreational or total minutes of vigorous-intensity physical activity, and moderate-intensity physical activity was not associated with 2-hour glucose (p>0.20). Additionally, none of the physical activity minutes was associated with fasting glucose (p>0.27). Conclusion: Self-reported vigorous-intensity physical activity during work was positively associated with 2-hour glucose, but not fasting glucose. The results are surprising. Further studies with objective physical activity measures are needed to examine the associations with fasting and 2-hour glucose.

Determining the level of physical activity estimated by the Canada Fitness Survey questionnaire using criteria of the International Physical Activity Questionnaire

Biomedical Human Kinetics ◽

10.1515/bhk-2016-0019 ◽

2016 ◽

Vol 8 (1) ◽

pp. 131-136

Author(s):

Alicja Kostencka ◽

Anna Pastuszak ◽

Krzysztof Buśko

Keyword(s):

Physical Activity ◽

Body Composition ◽

Physical Education ◽

Energy Expenditure ◽

Activity Levels ◽

Significant Relation ◽

Physical Activity Questionnaire ◽

Vigorous Intensity ◽

SummaryStudy aim: The aim of the study was to determine the weekly energy expenditure measuring MET/min/week based on data collected through the Canada Fitness Survey (CFS), according to the classification used in the International Physical Activity Questionnaire (IPAQ), and to verify the adopted method to assess the level of physical activity in students of physical education. Material and methods: The study involved 116 female students (21.1 ± 1.6) and 276 male students (21.2 ± 1.7), studying Physical Education at Kazimierz Wielki University. Physical activity (PA) of respondents assessed using the Canada Fitness Survey was converted to energy expenditure in MET/min/week using the criteria established in the IPAQ. Body composition was assessed according to bioelectrical impedance. Results: A significantly smaller fat fraction was observed in the group of students with high physical activity (PA) (p < 0.01). In women, there was a significant relation between FAT% and all analysed characteristics of physical activity: total physical activity (TPA) – 0.274, vigorous intensity (VI) – 0.216, number of days spent on physical activity (DTPA) – 0.199 and number of days spent on vigorous intensity (DVI) – 0.202 (p < 0.05). In men, a significant relation was found between all the analysed tissue components and the adopted variables of PA (FAT% vs. TPA – 0.145, VI – 0.203, DTPA – 0.187; FATkg vs. TPA – 0.123, VI – 0.186, DTPA – 0.178; FATkg vs. DVI – 0.131). BMI significantly correlated with VI (–0.162) and DVI (–0.140), p < 0.05. Conclusions: Based on data collected using the CFS on the type and frequency of PA during a week, we can determine the level of activity in a measurable way, using the IPAQ classification. There is a significant relationship between thus determined physical activity levels and body composition in both women and men, which proves the accuracy of the adopted method of converting weekly energy expenditure to MET/min/week.

PHYSICAL ACTIVITY LEVEL OF FIRSTYEAR STUDENTS FROM JOZEF PILSUDSKI UNIVERSITY OF PHYSICAL EDUCATION IN WARSAW

Journal of Kinesiology and Exercise Sciences ◽

10.5604/01.3001.0010.0928 ◽

2016 ◽

Vol 26 (76) ◽

pp. 61-70

Author(s):

Karol Gryko ◽

Krzysztof Perkowski ◽

Anna Kopiczko ◽

Damian Włoch

Keyword(s):

Physical Activity ◽

Physical Education ◽

Activity Level ◽

First Year ◽

First Year Students ◽

Physical Activity Questionnaire ◽

Vigorous Intensity ◽

Aim: The aim of the study was to evaluate the level of declared physical activity of first-year students from Jozef Pilsudski University of Physical Education in Warsaw by using the International Physical Activity Questionnaire (IPAQ). The paper presents physical activity according to the students’ chosen degree course and sex. The study also analyzes physical activity in relation to the BMI index according to the classification by the World Health Organization (WHO). Basic procedures: The group of participants comprised 190 Physical Education (n = 115) and Sports (n = 75) students. The study was conducted in November 2015 and used the short version of the International Physical Activity Questionnaire. Main findings: The results of the present study showed that the physical education students were characterized by a higher level of physical activity in each discussed type of physical activity than their peers studying sports. The study also revealed that the women showed greater physical activity than the men. It was only in vigorous-intensity physical activity that the men obtained higher results than the women. Conclusions: The male first-year students of the University of Physical Education in Warsaw prefer vigorous-intensity physical activity, and the female students prefer both moderate-intensity activities and walking. With the development of sports infrastructure and the growing number of sports services, women have become more physically active and achieve results rivaling, or at times, surpassing the results obtained by men.

Associations of Type, Organization, and Number of Recreational Activities With Total Activity

Journal of Physical Activity and Health ◽

10.1123/jpah.4.4.470 ◽

2007 ◽

Vol 4 (4) ◽

pp. 470-481

Author(s):

Heather R. Bowles ◽

Dafna Merom ◽

Tien Chey ◽

Ben J. Smith ◽

Adrian Bauman

Keyword(s):

Physical Activity ◽

Total Activity ◽

Population Based ◽

Recreational Activity ◽

Activity Type ◽

Active Lifestyle ◽

Physical Activity Questionnaire ◽

Recreational Activities ◽

Background:The aim of this study was to examine the associations between characteristics of recreational activity and total physical activity (PA).Methods:Recreational activity type and number were assessed for 3,385 adult respondents to the population-based Exercise Recreation and Sport Survey and categorized as “no recreational activity,” “walking only,” “sport only,” or “combined walking and sport.” Total PA was assessed by the International Physical Activity Questionnaire and categorized as “low,” “moderate,” or “high.”Results:Odds of high total PA were 1.7 times greater among walking-only participants, 2.9 times greater among sport-only participants, and 3.3 times greater among participants in combined walking and sport compared to no recreational activity participants. Greater number of recreational activities related to increased odds of high total PA. Similar associations were observed between recreational activity and moderate total PA.Conclusion:Participants in more than one type of recreational activity were less likely to have a low-active lifestyle.

Level of Physical Activity on the Body Image of Young Women

Journal of Morphological Sciences ◽

10.1055/s-0039-1693721 ◽

2019 ◽

Vol 36 (03) ◽

pp. 156-161

Author(s):

Katielly Santana ◽

Almir de França Ferraz ◽

André Rodrigues Lourenço Dias ◽

Rosilene Andrade Silva Rodrigues ◽

Camila Pasa ◽

...

Keyword(s):

Physical Activity ◽

Body Image ◽

Body Image Dissatisfaction ◽

The Body ◽

Lower Amount ◽

Body Images ◽

Education Professionals ◽

Vigorous Intensity ◽

Different Levels ◽

AbstractPhysical exercise has the ability to alter the measurements of the body related to esthetic. The objective of the present study was to compare the body image and body esthetic between two groups of women with different levels of physical activity. We evaluated 79 women who were divided into 2 groups: 39 women with low or moderate levels of physical activity, and 40 women with high levels of physical activity according to the International Physical Activity Questionnaire (IPAQ). Anthropometric and body composition measurements were taken using the InBody S10 multifrequency device (InBody Co., Eonju-ro, Gangnam-gu, Seoul, South Korea). The scale of silhouettes, which is composed of 9 engravings of body images, was used to verify the body image, as well as the Portuguese version of the Body Shape Questionnaire (BSQ) validated for university students. The group of evaluators was composed of twenty physical education professionals of both sexes, ten male and ten female. The group with low/moderate levels of physical activity, as expected, showed a lower amount (minutes per week) of physical activity of mild, moderate and vigorous intensity when compared with the group with high levels of physical activity (p < 0.05), and they also had a higher ratio of fat mass (FM) per height squared (p = 0.047). The BSQ questionnaire scores, the current and ideal silhouettes, as well as body image dissatisfaction, were not different between the groups (p > 0.05). The overall body esthetic score, attributed only by the male and only by the female evaluators, did not differ significantly (p > 0.05). We concluded that the level of physical activity did not influence the body image and body esthetic of the women.

Predictivity of International Physical Activity Questionnaire Short Form for 5-Year Incident Disability Among Japanese Older Adults

Journal of Physical Activity and Health ◽

10.1123/jpah.2021-0247 ◽

2021 ◽

pp. 1-5

Author(s):

Satoshi Kurita ◽

Takehiko Doi ◽

Kota Tsutsumimoto ◽

Sho Nakakubo ◽

Hideaki Ishii ◽

...

Keyword(s):

Physical Activity ◽

Older Adults ◽

Short Form ◽

Physically Active ◽

Vigorous Intensity ◽

Japanese Older Adults ◽

Activity Questionnaire ◽

Physically Inactive

Background: This study aimed to examine whether physical activity measured using the International Physical Activity Questionnaire Short Form (IPAQ-SF) can predict incident disability in Japanese older adults. Methods: Community-dwelling older adults participated in a prospective cohort survey. The time spent in moderate- to vigorous-intensity physical activity was assessed at the survey baseline using the IPAQ-SF. The participants were categorized into those who spent ≥150 minutes per week (physically active) or <150 minutes per week (physically inactive) in moderate- to vigorous-intensity physical activity. Incident disability was monitored through Long-Term Care Insurance certification during a follow-up lasting 5 years. Results: Among the 4387 analyzable participants (mean age = 75.8 y, 53.5% female), the IPAQ-SF grouped 1577 (35.9%) and 2810 (64.1%) participants as those who were physically active and inactive, respectively. A log-rank test showed a significantly higher incidence of disability among the inactive group of participants (P < .001). The Cox proportional hazards model showed that physically inactive participants had a higher risk of incident disability than the physically active ones did, even after adjusting for covariates (hazard ratio, 1.24; 95% CI, 1.07–1.45, P < .001). Conclusions: Older adults identified as physically inactive using the IPAQ-SF had a greater risk of developing disabilities than those identified as physically active. The IPAQ-SF seems to be appropriate to estimate the incidence risk of disability.