scholarly journals RELATIONSHIP BETWEEN THE FUNCTIONAL RESERVE OF THE HEART AND THE PHYSICAL FACILITY OF ADOLESCENTS OF THE SPECIAL MEDICAL GROUP

2021 ◽  
Vol 17 (1) ◽  
pp. 83-92
Author(s):  
A.M. Sitovskyi ◽  
O.Ya. Andriychuk ◽  
O.V. Usova ◽  
O.O. Yakobson ◽  
N.Ya. Ulianytska ◽  
...  
Keyword(s):  
Cardiovascular System ◽  
Physical Performance ◽  
Rank Correlation ◽  
Medical Group ◽  
Functional Reserve ◽  
Diagnostic Significance ◽  
Health Technologies ◽  
Adaptive Capabilities ◽  
Wide Range ◽  
Medical Groups

Relevance. The most common indicators for assessing the effectiveness of health technologies are the cardiovascular performance of adolescents. At present, there is insufficient information on the quantitative substantiation of informativeness, prognostic and diagnostic significance of such indicators in the process of correction of functional and reserve capabilities of the cardiovascular system of adolescents. Purpose: To determine the levels of functional reserve of the heart according to the Rufier index and to study the physical performance of students aged 12-14 years of different medical groups. Materials and methods. 178 seventh-eighth-graders aged 12-14 (85 boys and 93 girls) were examined. All students voluntarily participated in this experiment, and the written consent of their parents was obtained. Physical performance was studied according to the parameters of the bicycle ergometric test PWC170. The division of students into medical groups was carried out according to the indicators of the level of functional and reserve capabilities of the cardiovascular system, conducted according to the Rufier index. Statistical analysis of the results was performed using the application package Statistica-V.10.0. The normality of the distribution was checked by the Kolmogorov-Smirnov test. The studied indicators are described by the median (Me) and 25, 75 percentiles. The relationships of the studied indicators were analyzed according to Spearman's rank correlation coefficients. To determine the reliability of differences in indicators used the criterion of Kraskel Wallis. Results. The main group included 13.5% of adolescents, the preparatory group – 35.4%, the special medical group – 51.1% of students. Among student-athletes, 25.9% of boys and 45.4% of girls belong to a special medical group. In school athletes, the correlations between the Rufier index and the PWC170 test are low and statistically insignificant. Indicators of physical performance in the range of 25-75 percentiles do not differ in different medical groups. This indicates that in a special medical group there are students with medium and high levels of physical fitness. Conclusions. The established age and gender differences in the functional reserve of the heart of schoolchildren determine the need to develop differentiated approaches to the assessment of the Rufier index. Physical performance in different medical groups varies in a fairly wide range. The division of students into medical groups according to the Rufier index does not reflect the level of physical performance of students and, accordingly, their real adaptive capabilities. Further studies are needed on the informativeness of using the Rufier test to divide students into medical groups.

scholarly journals Peculiarities of changes of psychophysiological functions, state of human adaptive capacity and stress resistance of students of higher medical institutions

2021 ◽  
Vol 26 (4) ◽  
pp. 98-103
Author(s):  
S.I.  Kalashchenko
Keyword(s):  
Adaptive Capacity ◽  
Short Term Memory ◽  
Viral Infections ◽  
Rank Correlation ◽  
Functional Mobility ◽  
Short Term ◽  
Term Memory ◽  
Adaptive Capabilities ◽  
Medical Institutions ◽  
Psychophysiological Functions

The study is devoted to assessing the psychophysiological adaptive capabilities of students of higher medical institutions. There was conducted a screening study on the basis of which a correlation analysis of a group of 42 students was performed. The main inclusion criterion was good physical activity. Exclusion criteria - the presence of chronic diseases, acute respiratory viral infections at the time of examination, taking antidepressants or psychoactive substances. The study was aimed to identify the peculiarities of changes in psychophysiological functions and the state of adaptive capacity of students of higher medical institutions being in stressful conditions. The following methods from the software and hardware complex "Psycholot-1" were used for the study: "Functional mobility of nervous processes according to Khilchenko" and "Memory." The survey was conducted under micro-stress, it means all tasks had to be completed in a limited period. Statistical analysis of the data was performed to establish correlations between psychophysiological indicators of short-term memory and functional mobility of nervous processes  (Spearman's rank correlation index). It was found that the faster the stimulus appears in conditions of time deficit, the lower the mobility of nervous processes in the student, which is directly reflected in the indicators in increasing the minimum exposure time of the figure on the screen (0.27±0.007 s). In addition, a relationship was found between the rate of reaction of the left hand to a stimulus and the amount of information that a person can store in short-term memory. The information obtained will help to determine the initial data of the adaptive capacity of a potentially healthy contingent of people and predict their success in further professional activities in the sphere of medicine.

scholarly journals Influence of Physical Therapy Means on Indicators of Cardiovascular System Activity, Metabolism and Psychoemotional Status of Elderly Individuals with Metabolic Syndrome and Frailty

2021 ◽  
Vol 6 (1) ◽  
pp. 271-279
Author(s):  
N. P. Koval ◽  
Keyword(s):  
Metabolic Syndrome ◽  
Heart Rate ◽  
Physical Therapy ◽  
Therapeutic Alliance ◽  
Cardiovascular System ◽  
Elderly People ◽  
Physical Performance ◽  
Biochemical Parameters ◽  
Adaptive Potential ◽  
Low Level

An increase in the prevalence of insulin resistance in the elderly, associated with physiological changes in carbohydrate metabolism during the aging process, is associated with a high risk of cardiovascular accidents and endocrine diseases. This problem requires a solution by healthcare professionals with medication and non-medication. The purpose of the study was to determine the effectiveness of the program of physical therapy by the dynamics of indicators of the cardiovascular system, carbohydrate and lipid metabolism, psychoemotional status of elderly people with frailty and metabolic syndrome. Material and methods. 96 elderly people were examined. The control group consisted of persons without metabolic syndrome and without frailty. The main group 1 consisted of patients with metabolic syndrome and frailty with a low level of therapeutic alliance who did not want to cooperate with a physical therapist and / or actively improve their health on their own. The main group 2 included patients who agreed to undergo a developed program of physical therapy (a high level of therapeutic alliance) using kinesitherapy, massage, nutritional correction, education of the patient and his family, elements of cognitive training and occupational therapy for 1 year. The effectiveness of the program was assessed by the dynamics of systolic and diastolic blood pressure, heart rate, Kvass endurance coefficient, Baevsky's adaptive potential, Robinson's index, physical performance (based on the results of a 6-minute test), carbohydrate parameters (fasting blood glucose and after glucose load) and lipid (concentration of cholesterol, triglycerides, high density lipoproteins) metabolism, the level of depression according to the GDS-15 questionnaire. Results and discussion. In elderly people with frailty and metabolic syndrome, a statistically significant (p <0.05) deterioration in the parameters of the functioning of the cardiovascular system (according to the levels of DBP, heart rate at rest, Kvass endurance coefficient, Baevsky's adaptive potential, Robinson's index), physical performance (according to the results of a 6-minute test - distance, severity of fatigue, shortness of breath, cardialgia), biochemical parameters (fasting hyperglycemia, impaired glucose tolerance, atherogenic dyslipidemia), psycho-emotional state (depression) from their peers. The use of physical therapy tools led to a statistically significant improvement (p <0.05) of all the studied parameters of the functioning of the cardiovascular system, biochemical parameters in elderly people with metabolic syndrome and frailty, an increase in their physical performance, and an improvement in psycho-emotional status. A low level of therapeutic / rehabilitative alliance led to unsatisfactory fulfillment or non-fulfillment of the recommendations provided by patients and is associated with a lack of improvement in the state of the cardiovascular system, physical performance, age-associated depression. Conclusion. It is advisable to include physical therapy means in the rehabilitation programs for elderly patients with comorbid pathology like frailty and metabolic syndrome for the prevention of cardiovascular accidents

PP238 Budget Impact Of Methionine-Free Amino Acid Formula For Homocystinuria

2019 ◽  
Vol 35 (S1) ◽  
pp. 75-75
Author(s):  
Eduardo Mulinari ◽  
Nayara Castelano Brito ◽  
Lays Pires Marra
Keyword(s):  
Amino Acid ◽  
Free Amino Acid ◽  
Free Amino ◽  
Budget Impact ◽  
National Committee ◽  
Budgetary Impact ◽  
Health Technologies ◽  
Number Of Patients ◽  
Wide Range ◽  
Amino Acid Formula

IntroductionThe National Committee for Health Technology Incorporation (CONITEC) evaluates health technologies to recommend their inclusion or exclusion within the Brazilian Public Health System (SUS), and uses the budget impact assessment to estimate costs to the system. This study estimated the budget impact of the supply of methionine-free amino acid formula (MFAAf) for patients with classical homocystinuria (HCU) in the SUS.MethodsThe incidence of one case per 250,000 live births in Brazil and the registration of a Brazilian association of patients with HCU was assumed to calculate the population. Mortality and responsiveness to pyridoxine rates were applied. The costs of treatment were estimated according to the recommended dosage in literature and public purchasing prices. For calculating the dose of MFAAf patients, a median age of 19 years and weight of 60 kg were assumed, according to Brazilian study data.ResultsThe annual cost of treatment was estimated at BRL 77,000 (USD 21,084) per patient. The incorporation of MFAAf for HCU would generate a budget impact in SUS of around BRL 37 million (USD 10.1 million) in 2019 and BRL 188 million (USD 51.5 million) after five years which considers the epidemiological data, and a budget impact of around BRL 6.4 million (USD 1.75 million) in 2019 and BRL 33 million (USD 9 million) after five years which considers the information of a Brazilian association of patients with HCU. The wide range of values in the incremental budgetary impact is due to the lack of information on the epidemiology of the disease in Brazil.ConclusionsThe incorporation of the MFAAf in the SUS represents an important budgetary impact and covers a small number of patients. CONITEC recommended the incorporation of the MFAAf in the SUS, according to clinical protocol.

scholarly journals Use of mobile health technologies for postoperative care in paediatric surgery: A systematic review

2020 ◽  
pp. 1357633X2093468
Author(s):  
Nam Nguyen ◽  
Etienne Leveille ◽  
Elena Guadagno ◽  
Luc Malemo Kalisya ◽  
Dan Poenaru
Keyword(s):  
Systematic Review ◽  
Mobile Health ◽  
Postoperative Care ◽  
Data Extraction ◽  
Intervention Group ◽  
Paediatric Surgery ◽  
High Quality Research ◽  
Health Technologies ◽  
Surgery Patient ◽  
Wide Range

Introduction Mobile health (mHealth) is the use of mobile communication devices such as smartphones, wireless patient monitoring devices and tablet computers to deliver health services. Paediatric surgery patient care could potentially benefit from these technologies. This systematic review summarises the current literature on the use of mHealth for postoperative care after children’s surgery. Methods Seven databases were searched by a senior medical librarian. Studies were included if they reported the use of mHealth systems for postoperative care for children  <18 years old. Data extraction and risk of bias assessment were performed in duplicate. Results A total of 18 studies were included after screening. mHealth use was varied and included appointment or medication reminders, postoperative monitoring and postoperative instruction delivery. mHealth systems included texting systems and mobile applications, and were implemented for a wide range of surgical conditions and countries. Discussion Studies showed that mHealth systems can increase the postoperative follow-up appointment attendance rate ( p < 0.001), decrease the rate of postoperative complications and returns to the emergency department and reliably monitor postoperative pain. mHealth systems were generally appreciated by patients. Most non-randomised and randomised studies had many methodological problems, including lack of appropriate control groups, lack of blinding and a tendency to devote more time to the care of the intervention group. mHealth systems have the potential to improve postoperative care, but the lack of high-quality research evaluating their impact calls for further studies exploring evidence-based mHealth implementation.

OP101 Do We Need To Extend Health Technology Assessment To Health Enhancement Assessment?

2017 ◽  
Vol 33 (S1) ◽  
pp. 46-46
Author(s):  
Bjørn Hofmann
Keyword(s):  
Health Care ◽  
Health Technology Assessment ◽  
Technology Assessment ◽  
Cognitive Abilities ◽  
Literature Search ◽  
Ethical Issues ◽  
Health Technology ◽  
Health Technologies ◽  
Health And Wellbeing ◽  
Wide Range

INTRODUCTION:Several health technologies used for therapy can also be used for health enhancement. Drugs stimulating cognitive abilities are but one example. Health Technology Assessment (HTA) has not been developed for assessing enhancements. This raises the question of how HTA should address the blurred distinction between therapy and enhancement. Should we (i) carve out a distinction between therapy and enhancement and limit HTA to therapy, (ii) use HTA for both therapy and enhancement (with some modifications), or (iii) should we develop a separate health enhancement assessment (HEA)?METHODS:A literature search of the medical, philosophical, and bioethical literature was conducted for debates, arguments, and suggested solutions to the issue of therapy versus enhancement.RESULTS:The same improvement in health may be therapeutic in one patient, but an enhancement in another. Moreover, both therapy and enhancement share the same goal: increased health and wellbeing. A wide range of arguments try to establish a difference between therapy and enhancement. They refer to naturalness, rehabilitation, normality, species-typical functioning/potential, disease, sustainability, and responsibility. On closer scrutiny few of these arguments do the job in bolstering the therapy-enhancement distinction. We already use a wide range of means to extend human abilities. Moreover, the therapy-enhancement distinction raises a wide range of ethical issues that are relevant for the assessment of a number of emerging health technologies.CONCLUSIONS:Existing HTA methodology can address a wide range of non-therapeutic health enhancements. However, a series of broader issues related to the goal of health care and responsibility for altering human evolution may not be addressed within traditional HTA frameworks. Specific HEAs may therefore be helpful.

scholarly journals Prospective long-term follow-up analysis of the cardiovascular system in marathon runners: study design of the Pro-MagIC study

2020 ◽  
Vol 6 (1) ◽  
pp. e000786
Author(s):  
Julia Schoenfeld ◽  
Michael Johannes Schindler ◽  
Bernhard Haller ◽  
Stefan Holdenrieder ◽  
David Christopher Nieman ◽  
...  
Keyword(s):  
Cardiovascular System ◽  
Cardiopulmonary Exercise Testing ◽  
Strenuous Exercise ◽  
Ventricular Ejection Fraction ◽  
Cardiovascular Changes ◽  
Link Type ◽  
Wide Range ◽  
Exercise Induced

IntroductionProlonged strenuous exercise training may result in structural, functional and electrical cardiac remodelling, as well as vascular and myocardial injuries. However, the extent to which high-volume, intense exercise is associated with arrhythmias, myocardial fibrosis, coronary heart disease and pathological alterations of the vasculature remains unknown. In addition, there is no clear consensus on the clinical significance of these exercise-induced changes. Previous studies typically used cross-sectional designs and examined exercise-induced cardiovascular changes in small cohorts of athletes for up to 3–7 days of recovery. Long-term longitudinal studies investigating cardiovascular changes induced by prolonged strenuous exercise in large cohorts of athletes are needed to improve scientific understanding in this area.Methods and analysisIn this prospective observational monocenter study, 277 participants of the Beer, Marathon, Genetics, Inflammation and the Cardiovascular System (Be-MaGIC) study (ClinicalTrials.gov: NCT00933218) will be invited to participate in this 10-year follow-up study. A minimum target sample size of 130 participants will be included in the study. Participating athletes will be examined via the following: anthropometry, resting electrocardiography and echocardiography, blood sampling, retinal vessel diameters, carotid sonography and cardiopulmonary exercise testing, including exercise electrocardiography.DiscussionThis longitudinal study will provide comprehensive data on physiological changes in the cardiovascular system and the development of pathologies after a 10-year period of prolonged and strenuous endurance exercise. Since the participants will have engaged in a wide range of training loads and competitive race events, this study will provide useful risk factor determinants and training load cut-off values. The primary endpoint is the association between the exercise-induced increase in cardiac troponin during the Munich marathon 2009 and the decline in right ventricular ejection fraction over the next 10 years.Trial registration numberNCT04166903.

scholarly journals The Effects of Cannabidiol, a Non-Intoxicating Compound of Cannabis, on the Cardiovascular System in Health and Disease

2020 ◽  
Vol 21 (18) ◽  
pp. 6740
Author(s):  
Aleksandra Kicman ◽  
Marek Toczek
Keyword(s):  
Cardiovascular Diseases ◽  
Cardiovascular System ◽  
Heart Diseases ◽  
Ischemia Reperfusion ◽  
Antioxidant Properties ◽  
Positive Effects ◽  
Nitrative Stress ◽  
Cardiovascular Side Effects ◽  
Wide Range ◽  
Health And Disease

Cannabidiol (CBD) is a non-intoxicating and generally well-tolerated constituent of cannabis which exhibits potential beneficial properties in a wide range of diseases, including cardiovascular disorders. Due to its complex mechanism of action, CBD may affect the cardiovascular system in different ways. Thus, we reviewed the influence of CBD on this system in health and disease to determine the potential risk of cardiovascular side effects during CBD use for medical and wellness purposes and to elucidate its therapeutic potential in cardiovascular diseases. Administration of CBD to healthy volunteers or animals usually does not markedly affect hemodynamic parameters. Although CBD has been found to exhibit vasodilatory and antioxidant properties in hypertension, it has not affected blood pressure in hypertensive animals. Hypotensive action of CBD has been mainly revealed under stress conditions. Many positive effects of CBD have been observed in experimental models of heart diseases (myocardial infarction, cardiomyopathy, myocarditis), stroke, neonatal hypoxic ischemic encephalopathy, sepsis-related encephalitis, cardiovascular complications of diabetes, and ischemia/reperfusion injures of liver and kidneys. In these pathological conditions CBD decreased organ damage and dysfunction, oxidative and nitrative stress, inflammatory processes and apoptosis, among others. Nevertheless, further clinical research is needed to recommend the use of CBD in the treatment of cardiovascular diseases.

Research on Evaluation of Energy Saving and Loss Decreasing Based on Rank Correlation Analysis in Power Distribution Networks

2014 ◽  
Vol 962-965 ◽  
pp. 1635-1640
Author(s):  
Shu Xin Li ◽  
Wen Ying Liu ◽  
Yu Ze Zhang ◽  
Wei Zhou Wang ◽  
Fu Chao Liu
Keyword(s):  
Correlation Analysis ◽  
Energy Saving ◽  
Power Distribution ◽  
Index System ◽  
Rank Correlation ◽  
Evaluation Process ◽  
Distribution Networks ◽  
Power Distribution Networks ◽  
Research On Evaluation ◽  
Wide Range

In this paper, a series of scientifically rational index system is set up to evaluate the effect of energy saving and loss decreasing in power distribution networks. The establishment of the index system is based on a variety of new technical measures. According to the feature of wide range and weak consistency, an evaluation in power distribution networks based on rank correlation analysis is proposed. In such a way, the procedure is clear, simple and highly exercisable. With the application of evaluation process described in this paper, present situation in power distribution networks in a region is evaluated, which justifies the validity of the method.

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