scholarly journals Analysis of Orthopaedic Sequelae of Special Treatment of Malignant Tumors in Children

2014 ◽  
pp. 54-58
Author(s):  
A. V. Petrichenko ◽  
E. A. Bukreeva ◽  
A. V. Korneeva ◽  
I. A. Shavyrin ◽  
A. A. Ochkurenko ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bone Metabolism ◽  
Motor System ◽  
Malignant Tumors ◽  
Social Adaptation ◽  
Special Treatment ◽  
Joint Movement ◽  
Metabolism Disorder ◽  
Muscular Tension

Ninety five patients (mean age 13.72±4.2) with complaints on loco-motor system disorders after special treatment for malignant tumors were under observation of orthopaedic surgeon. The most common sequelae of treatment were muscular hypotrophy (66 children), I-III degree scoliosis (75), rigidity (61), bone metabolism disorder and osteopenia (47), one limb shortening even in presence of “growing” endoprosthesis (46). Individual rehabilitation course was performed in 43 (45.3%) children and resulted in increase of joint movement range, improvement of posture, and increase in muscular tension. Timely performed complex of rehabilitation measures enabled to correct sequelae of special treatment at early terms that significantly decreased disability of children, increases their social adaptation and quality of life.

scholarly journals Analysis of Orthopaedic Sequelae of Special Treatment of Malignant Tumors in Children

2014 ◽  
Vol 21 (4) ◽  
pp. 54-58
Author(s):  
A. V Petrichenko ◽  
E. A Bukreeva ◽  
A. V Korneeva ◽  
I. A Shavyrin ◽  
A. A Ochkurenko ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bone Metabolism ◽  
Motor System ◽  
Malignant Tumors ◽  
Social Adaptation ◽  
Special Treatment ◽  
Joint Movement ◽  
Metabolism Disorder ◽  
Muscular Tension

Ninety five patients (mean age 13.72±4.2) with complaints on loco-motor system disorders after special treatment for malignant tumors were under observation of orthopaedic surgeon. The most common sequelae of treatment were muscular hypotrophy (66 children), I-III degree scoliosis (75), rigidity (61), bone metabolism disorder and osteopenia (47), one limb shortening even in presence of “growing” endoprosthesis (46). Individual rehabilitation course was performed in 43 (45.3%) children and resulted in increase of joint movement range, improvement of posture, and increase in muscular tension. Timely performed complex of rehabilitation measures enabled to correct sequelae of special treatment at early terms that significantly decreased disability of children, increases their social adaptation and quality of life.

scholarly journals Orthopedic treatment in cancer patients with maxillofacial pathology

2021 ◽  
Vol 2 (2) ◽  
pp. 22-33
Author(s):  
I. V. Pustovaya ◽  
M. A. Engibaryan ◽  
P. V. Svetitskiy ◽  
I. V. Aedinova ◽  
V. L. Volkova ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Soft Tissues ◽  
Malignant Tumors ◽  
Social Adaptation ◽  
Research Centre ◽  
Orthopedic Treatment ◽  
National Medical ◽  
Upper Jaw ◽  
The Aesthetic

Relevance. Staged orthopedic treatment was used to improve the quality of life of patients who underwent radical maxillofacial surgeries for cancer.Patients and methods. 197 patients receiving treatment for maxillofacial cancer were observed at the Department of head and neck tumors, National Medical Research Centre for Oncology of the Ministry of Health of Russia, in 1998- 2018. All patients underwent radical surgical treatment resulting in postoperative defects of the upper jaw, soft tissues of the zygomatic- buccal-orbital region, nose, or auricle.Results. Removable obturator prostheses with various supporting and retaining elements were made for 159 (80.7 %) patients. Individual facial prostheses were made for 38 (19.3 %) patients: 17 (44.7 %) – external orbital prostheses, 14 (36.8 %) – external nasal prostheses, 6 (15.8 %) – external zygomatic- buccal-orbital prostheses, 1 (2.7 %) – external auricle prosthesis. Combined prostheses were made for 4 patients– removable upper jaw obturator and nose prosthe[1]sis; removable upper jaw obturator and eye prosthesis. Combined prostheses were fixed to each other using magnets. The results of maxillofacial prosthetics were evaluated according to the aesthetic requirements of the patients and their quality of life. Maxillofacial prostheses allowed a complete restoration of chewing, swallowing, and speaking, restored facial deformation, and improved the appearance of patients.Conclusions. Timely and comprehensive orthopedic treatment of patients with postoperative maxillofacial defects after radical surgeries for malignant tumors takes the main place in the complex of rehabilitation measures. Early elimination of extensive defects is aimed at maximum restoration of oral dysfunctions and appearance preservation. The apparent advantages of maxillofacial prostheses involve improvement of social adaptation and the quality of life of patients, which promotes complete rehabilitation and a return to socially useful activities.

scholarly journals External genital endometriosis: treatment and rehabilitation

2020 ◽  
Author(s):  
A. G. Solopova ◽  
E. E. Achkasov ◽  
V. S. Moskvichyova ◽  
E. Grigorevskaya ◽  
D. M. Ampilogova
Keyword(s):  
Quality Of Life ◽  
Malignant Tumors ◽  
Pathological Process ◽  
Social Adaptation ◽  
Cochrane Library ◽  
Current View ◽  
Comprehensive Treatment ◽  
Modern Approach ◽  
Rehabilitation Programs

Aim: to systematize data on rehabilitation methods and management tactics for women with external form of genital endometriosis.Materials and Methods. We searched for publications in international scientific databases: scientific electronic library eLibrary, Scholar, ScienceDirect, Cochrane Library, PubMed/MEDLINE for the last 5 years. The data on the modern approach to the therapy and rehabilitation of women with external genital endometriosis are presented. Search terms in Russian and English were used: “endometriosis”, “rehabilitation”, “gynecology”, “quality of life”.Results. Endometriosis is considered an independent risk factor for the development of malignant tumors not only of the reproductive system, but also of the large intestine, bladder, mammary glands. The review presents a current view of the treatment and rehabilitation of women with external genital endometriosis. Endometriosis is a polyetiological disease that can manifest itself as dysmenorrhea, dyspareunia, chronic pelvic pain, as well as dysuria and dyshesia when involving adjacent organs in the pathological process. Relapses, infertility, emotional and psychosexual disorders, problems with socialization are often detected in these patients.Conclusion. It is necessary not only to conduct comprehensive treatment, but also to develop personalized rehabilitation programs that can improve the quality of life, as well as create comfortable conditions for social adaptation in society.

scholarly journals Quality of life and psychological status of thoracic and abdominal pediatric cancer survivors

2019 ◽  
Vol 21 (2) ◽  
pp. 55-60
Author(s):  
Svetlana N Mikhailova ◽  
Olga V Sachuk ◽  
Elena N Sukhanovskaya ◽  
Timur T Valiev ◽  
Anatolii P Kazantsev ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Malignant Tumors ◽  
Personality Development ◽  
Integrated Approach ◽  
Psychosocial Adaptation ◽  
Social Adaptation ◽  
Psychological Status ◽  
Psychological State ◽  
Adaptation Measures

Relevance. The integrated approach in the treatment of malignant tumors in the chest or abdomen combined with achievements of surgery, chemotherapy and accompanying therapy significantly increased survival rate and recovery in paediatric patients and then specialists faced the new challenge - to improve indicators of the quality of life (QOL) in cured patients. The aim. To study indicators of the QOL and psychological characteristics of personality development in patients cured in childhood of tumors in the chest or abdomen. Materials and methods. The study included 184 patient aged between 8 and 18 years, cured of tumors in the chest or abdomen in RAMS N.N.Blokhin RCRC Pediatric Oncology and Hematology Research Institute of Ministry of Health of Russia from 1979 to 2015. The follow-up period was 3-25 years after the end of the complex antitumor treatment. The QOL analysis was held in 92 (50%) of patients. The QOL analysis was performed according to the examining children’s questioning in the PedsQL questionary. In addition, we assessed the psychological state and social adaptation measures in patients cured of tumors in the chest or abdomen. Results. The analysis demonstrated the reduction of the indicators of the QOL and psychosocial adaptation in patients cured of tumors in the chest or abdomen. Most often the reduction of adaptation occurred in adolescents (78%). We marked the increase in the frequency of medical care encounters of non-oncological profile, the decrease in cognitive function, hypererethism, indecisiveness and low self-confidence. Conclusions. We showed guidelines for the individual rehabilitation of patients cured of tumors in the chest or abdomen: sanatorium resort therapy, psychocorrective work, psychological rehabilitation for family of the patient.

MALIGNANT TUMORS ASSOCIATED WITH METABOLIC SYNDROME: THE EXPRESSION PROFILE OF THE TRANSCRIPTIONAL AND GROWTH FACTORS

2017 ◽  
Vol 63 (6) ◽  
pp. 817-823
Author(s):  
Natalya Yunusova ◽  
Irina Kondakova ◽  
Sergey Afanasev ◽  
Larisa Kolomiets ◽  
Alena Chernyshova
Keyword(s):  
Quality Of Life ◽  
Metabolic Syndrome ◽  
Growth Factors ◽  
Cell Motility ◽  
Expression Profile ◽  
Malignant Tumors ◽  
Molecular Targets ◽  
Factors Associated ◽  
High Incidence

The study of the pathogenetic features of malignant tumors associated with metabolic syndrome (MS) is relevant because of high incidence of these tumors. Investigations of the mechanisms of involvement of MS in the pathogenesis of cancer reasonably supplemented by the study of transcription and growth factors associated with energy imbalance of the cell and involved in proliferation, apoptosis, angiogenesis, cell motility and inflammation. More research is needed to identify the most promising molecular targets for therapy of malignant tumors associated with MS with a view to increasing the survival and quality of life of these patients.

THE ROLE OF COMPREHENSIVE GERIATRIC ASSESSMENT IN THE TREATMENT OF CANCER PATIENTS IN ELDERLY AND SENILE AGE

2020 ◽  
pp. 65-73
Author(s):  
Ю. В. Алексеева ◽  
Т. Ю. Семиглазова ◽  
Б. С. Каспаров ◽  
Е. В. Ткаченко ◽  
К. И. Прощаев ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Malignant Tumors ◽  
Adverse Outcomes ◽  
Geriatric Syndromes ◽  
Complex Treatment ◽  
Increase Life Expectancy ◽  
Specialized Treatment

Современные подходы к организации диагностики и лечения больных пожилого и старческого возраста со злокачественными новообразованиями позволяют улучшать качество жизни и увеличивать продолжительность жизни. Оценка гериатрического статуса в онкологии позволяет прогнозировать осложнения в процессе комплексного лечения, в том числе лекарственного, модифицировать терапию для уменьшения факторов риска неблагоприятных исходов, осуществлять отбор пациентов на специализированное лечение с использованием стандартных схем. Таким образом, своевременная оценка гериатрических синдромов и их коррекция способна расширить показания к специализированному лечению больных пожилого и старческого возраста. Modern approaches to the organization of diagnosis and treatment of elderly and senile patients with malignant tumors allow to maintain the necessary level of health, improve the quality of life and increase life expectancy. Assessment of geriatric status in Oncology allows: to predict complications during the complex treatment, including drug treatment; to modify treatment to reduce the risk factors of adverse outcomes; to select patients for specialized treatment using standard schemes. So, timely assessment of geriatric syndromes and their correction can expand the indications for specialized treatment of elderly and senile patients.

scholarly journals EVALUATION OF THE QUALITY OF LIFE IN PATIENTS WITH LUNG CARCINOMA AFTER PNEUMONECTOMY

2021 ◽  
Vol 20 (3) ◽  
pp. 90-97
Author(s):  
E. A. Toneev ◽  
O. V. Pikin ◽  
V. I. Orelkin ◽  
A. L. Charyshkin ◽  
A. A. Martynov ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Functional Status ◽  
Short Form ◽  
Special Treatment ◽  
Combined Modality Treatment ◽  
Concomitant Disease ◽  
Extent Of Surgery ◽  
Questionnaire Method

Background. Pneumonectomy is one of the most traumatic thoracic surgeries, leading to a significant decrease in the patient’s functional status. Despite numerous questionnaires, there is no standard approach to the study of the quality of life of patients who have undergone radical surgery for lung cancer.The purpose of the study was to conduct a retrospective analysis of the quality of life of patients who underwent pneumonectomy during the period 2017–2018, taking into account the extent of surgery, presence of concomitant disease and adjuvant antitumor treatment.Material and Methods. Changes in the quality of life (qol) during combined modality treatment were evaluated in 40 patients with non-small cell lung cancer. To assess the functional status, the criteria adopted for determining the surgical risk were used. The st. George`s Respiratory Questionnaire (sgrq) and Quality Outcomes study short-Form 36 (sf-36) were used to assess the respiratory system of patients. Data collection was carried out 12 months after surgery using a questionnaire method based on a direct survey of respondents.Conclusion. Postoperative special treatment significantly worsens both the functional parameters of patients and the quality of life. Thus, a multidisciplinary approach to the management of patient with participation of an oncologist, pulmonologist, physiotherapist, and rehabilitologist is required.

scholarly journals Possibilities and prospects for glucocorticoid withdrawal in systemic lupus erythematosus

2020 ◽  
Vol 14 (1) ◽  
pp. 6-11
Author(s):  
S. K. Solovyev ◽  
E. A. Aseeva ◽  
E. L. Nasonov ◽  
A. M. Lila ◽  
G. M. Koilubaeva
Keyword(s):  
Quality Of Life ◽  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Social Adaptation ◽  
The Other ◽  
Systemic Lupus ◽  
Low Disease Activity ◽  
Pathogenetic Therapy

The efficiency of glucocorticoid (GC) therapy for systemic lupus erythematosus (SLE) is beyond question and is confirmed by the experience gained over many decades of their use. However, there are many problems with prolonged GC use, even in its low and medium doses. In particular, the development of GC-associated irreversible organ damages significantly worsens prognosis and causes a decrease in quality of life and social adaptation and a substantial increase in treatment costs. On the other hand, the current capabilities of early diagnosis, pathogenetic therapy, and monitoring in many patients with SLE allow for maintaining low disease activity and remission, the conditions in which the feasibility of further GC treatment can and should be decided. The paper gives the data available in the literature and the authors’ own studies on the possibility and prospects of GC withdrawal in SLE patients in a stage of low disease activity and remission.

Perceived stress mediates the relationship between social adaptation and quality of life in individuals at ultra high risk of psychosis

2019 ◽  
Vol 13 (6) ◽  
pp. 1447-1454 ◽  
Author(s):  
Laura Ortega ◽  
Itziar Montalvo ◽  
Rosa Monseny ◽  
Elisabet Vilella ◽  
Javier Labad
Keyword(s):  
Quality Of Life ◽  
High Risk ◽  
Perceived Stress ◽  
Social Adaptation ◽  
Ultra High Risk ◽  
The Relationship

scholarly journals Diagnosis and treatment of Paget's disease of bone: a mini-review

2013 ◽  
Vol 57 (8) ◽  
pp. 577-582 ◽  
Author(s):  
Bruno Ferraz-de-Souza ◽  
Pedro Henrique Silveira Correa
Keyword(s):  
Quality Of Life ◽  
Bone Metabolism ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Paget’S Disease Of Bone ◽  
Diagnosis And Treatment ◽  
Laboratory Evaluation ◽  
Sustained Remission ◽  
Paget's Disease Of Bone

Paget's disease of bone (PDB) is a chronic progressive disorder of bone metabolism that may go undetected for many years, and endocrinologists should be alert to its clinical signs and promptly diagnose and treat PDB before it results in irreversible complications, such as deformity, fracture or neurological sequelae. Most commonly, PDB is suspected upon the incidental finding of elevated serum alkaline phosphatase levels or a radiographic abnormality in an otherwise healthy individual above 55 years of age. Some of these individuals may have symptoms such as bone pain or enlargement with increased warmth. In general, a basic laboratory evaluation of bone metabolism, plain radiographies of affected bones and bone scintigraphy are sufficient to corroborate the diagnosis. Antiresorptive therapy with bisphosphonates is the mainstay of treatment of symptomatic PDB, and intravenous zoledronic acid has emerged as an effective and safe treatment option, leading to sustained remission and improved quality of life. It is extremely important, though, to ensure calcium and vitamin D sufficiency before and during treatment in order to prevent hypocalcemia. The benefit of treating all asymptomatic patients is not clear, but treatment is warranted if the pagetic lesion is located in a site where progression to fracture, deformity, or compression would significantly impair the patient quality of life. This mini-review focuses on important aspects of the diagnosis and treatment of PDB.

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