scholarly journals Quantitative Antibiotic Use Profile in Typhoid

2020 ◽  
Vol 3 (3) ◽  
pp. 113-118
Author(s):  
Hidayatul Kurniawati ◽  
Marianti

Background. Typhoid fever is a common health problem in developing countries. Antibiotics are used to treat typhoidfever which is caused by a bacterial infection. Selection and use of appropriate and rational antibiotic therapy candetermine a success in treatment to avoid bacterial resistance and minimize drug side effects. This study aims todetermine the rationality of the use of antibiotics in adult patients diagnosed with typhoid fever in the InpatientInstallation of X Hospital in Yogyakarta. Method. Non-experimental research with descriptive observational researchdesign and retrospective data collection. The sample of this study was inpatients with a diagnosis of typhoid fever andwas recorded at the X Hospital Medical Records Installation in Yogyakarta for the period January 2016 - December2017 which was included in the inclusion criteria. Result. Data taken came from 75 medical records that were includedin the inclusion criteria. Patients were dominated by female patients as many as 64% and the adult age range was 18-30 years. The single most widely used antibiotic was levofloxacin in 27 cases (36%). The use of antibiotics with theright indication was 75 patients (100%), the right type was 75 patients (100%), the exact duration of administrationwas 64 patients (85.33%), the right dose was 73 patients (97.33%), the right interval was 73 patients (97.33%) and theright route of administration were 75 patients (100%). Conclusion. The rationality of using antibiotics is good withaccuracy> 75%.

2021 ◽  
Vol 17 (1) ◽  
pp. 7
Author(s):  
Hidayatul Kurniawati ◽  
Anisa Auliyanah

Abstract: Introduction: Urinary tract infection (UTI) is an infectious disease caused by the growth and proliferation of bacteria in the urinary tract, including infections in the bladder to the renal parenchyma with a certain number of bacteria in the urine. The use of antibiotics is therapy that commonly used to treat infectious diseases caused by bacteria. Irrational use of antibiotics can lead to bacterial resistance and toxicity. Objective: To determine the rationality of using antibiotics in adult patients with a urinary tract infection (UTI) in the X Hospital Yogyakarta from January-December 2017.Methods: This study is a non-experimental study with a descriptive observational study design and retrospective data collection. The sample of this study was inpatients with a diagnosis of urinary tract infection (UTI) and was recorded in the Medical Record X Hospital Yogyakarta for the period January-December 2017 which was included in the inclusion criteria. Results: Medical records that were included in the inclusion criteria were 61. The single most widely used antibiotic was ceftriaxone in 25 cases (44.64%) and the most widely used combination antibiotic was ceftazidime + levofloxacin in 2 cases (40%). The use of antibiotics with the right indication was 61 patients (100%), the right type was 61 patients (100%), the correct duration was 54 patients (88.52%), the right dose was 61 patients (100%), the right interval was 60 patients (98.36%) and the right route of administration was 61 patients (100%). Keywords: Urinary tract infection, antibiotic, rational


2021 ◽  
Vol 3 (2) ◽  
pp. 69-73
Author(s):  
Amanda Safithri Sinulingga ◽  
Novidawati Boru Situmorang ◽  
Mas Gabena Siregar

Tuberculosis is a disease caused by the bacterium Mycobacterium tuberculosis, a first- line anti-tuberculosis drug, namely Isoniazid (H) and Rifampicin (R). The increase in the number of Tb Lung patients from 2019 to 2020 at the RS Grandmed Lubuk Pakam encouraged researchers to conduct this study. The purpose of this study was to determine the description of the use of antituberculosis drugs and the rationality of the use of anti-tuberculosis drugs in pulmonary TB patients in RS Grandmed Lubuk Pakam in 2019. This study was a descriptive (non-experimental) study with retrospective data collection taken from patient medical records. Pulmonary tuberculosis at RS Grandmed Lubuk Pakam. Data was collected using purposive sampling technique in accordance with the inclusion criteria and exclusion criteria using the Data Collection Sheet. The number of samples used in the study is 76 medical records of patients diagnosed with pulmonary TB. Data analysis was performed using the Univariate with the help of SPSS. Results of the distribution of treatment duration data that most patients underwent treatment for <6 months, as many as 31 people (19.9%). Followed by patients with exactly 6 months length of 30 people (0.39%). Whereas patients from 6 months 16 people (21.1%). And the number of Chronic Disease that suffered by Diabetes Mellitus patients was 24 patients (14.5%). All three have a significant relationship to the patient's treatment outcomes. Whereas at the age range 18-24 years, 44 people (57.9%) were affected by pulmonary TB. and The results of the evaluation of the rationality of pulmonary TB treatment are the exact indications of (97.4%), (74 patients), the right patients by 100% (76 patients), the right drugs by (97.4%) (74 patients), and the correct dosage of 100% ( 76).


2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Hidayatul Kurniawati

Introduction: Urinary tract infection (UTI) is an infectious disease caused by the growth and proliferation of bacteria in the urinary tract, including infections in the bladder to the renal parenchyma with a certain number of bacteria in the urine. The use of antibiotics is therapy that commonly used to treat infectious diseases caused by bacteria. Irrational use of antibiotics can lead to bacterial resistance and toxicity. Objective: To determine the rationality of using antibiotics in adult patients with a urinary tract infection (UTI) in the X Hospital Yogyakarta from January-December 2017.Methods: This study is a non-experimental study with a descriptive observational study design and retrospective data collection. The sample of this study was inpatients with a diagnosis of urinary tract infection (UTI) and was recorded in the Medical Record X Hospital Yogyakarta for the period January-December 2017 which was included in the inclusion criteria. Results: Medical records that were included in the inclusion criteria were 61. The single most widely used antibiotic was ceftriaxone in 25 cases (44.64%) and the most widely used combination antibiotic was ceftazidime + levofloxacin in 2 cases (40%). The use of antibiotics with the right indication was 61 patients (100%), the right type was 61 patients (100%), the correct duration was 54 patients (88.52%), the right dose was 61 patients (100%), the right interval was 60 patients (98.36%) and the right route of administration was 61 patients (100%).


2018 ◽  
Vol 10 (1) ◽  
pp. 303
Author(s):  
Santi Purna Sari ◽  
Natasha Kurnia Salma S ◽  
Alfina Rianti

Objective: This study aimed to monitor the side effects of carbamazepine, phenytoin, and valproic acid, and combinations of these drugs in adultpatients with epilepsy, to raise awareness of the importance of drug side effect monitoring in hospitals.Methods: In this prospective study, descriptive data were collected from patients who met the inclusion criteria of complete samples. Primary datawere obtained using questionnaires, secondary data were collected from medical records, and analyses were performed using the Naranjo algorithm.Results: Among the 54 included patients, 38 (70.37%) of them experienced drug side effects, and the most frequently observed side effect occurredin 48.15% of study subjects.Conclusion: No correlation was identified between side effects and age (p=0.903) or gender (p=1.000).


2010 ◽  
Vol 18 (6) ◽  
pp. 1131-1137 ◽  
Author(s):  
Graziella Gasparotto Baiocco ◽  
Jefferson Luis Braga da Silva

The study aimed to analyze the history of the use of the peripherally inserted central catheters in adult patients admitted to hospital from 2000 to 2007. The historical cohort approach was used with retrospective data collection from medical records of the Catheter Group of the Moinhos de Vento Hospital Association in Porto Alegre, RS, totaling 229 catheters inserted. The growth curve in the use of the PICC was from 1 catheter inserted in 2000 to 57 in 2007. The most prevalent pathology was oncology (17.9%, n=41). In relation to the indications of use, antibiotic use prevailed (54.1%, n=124). In the radiological confirmation the vena cava was prevalent (68.1%, n=156). The use of the PICC in the hospital environment is expanding and nursing has a fundamental role in its insertion, maintenance and removal.


2021 ◽  
Vol 4 (1) ◽  
pp. 1-6
Author(s):  
Dini Mayasari ◽  
Delfi Mutiara Hutahean ◽  
Debi Dinha Octora

Gastritis is a disease caused by the bacterium Helicobacter phylory, this first gastritis drug, namely Antacids, Omeprazole, and Ranitidine. The increasing number of Gastritis patients from 2019 to 2020 at Grandmed Lubuk Pakam Hospital is encouraging researchers to conduct this study. The purpose of this study was to determine the description of the use of Gastritis drugs and the rationality of the use of Gastritis medications in Gastritis patients at Grandmed Lubuk Pakam Hospital in 2019. This study was a descriptive (non-experimental) study with retrospective data collection taken from patient medical records. Gastritis at Grandmed Lubuk Pakam Hospital. Data were collected using a purposive sampling technique in accordance with the inclusion criteria and exclusion criteria using the Data Collection Sheet. The number of samples used in this study were 64 medical records of patients diagnosed with gastritis. Data analysis was performed using Univariat with the help of SPSS. Results of distribution of duration of treatment data for which most patients undergo treatment. And the number of Chronic Diseases suffered by Diarrhea patients is 20 patients (31.2%). All three have a significant relationship with patient care outcomes. While in the age range 31-60 years, 45 people (70.3%) affected by gastritis. and The results of evaluating the rationality of treatment for gastritis are the right indications (96.9%), (62 patients), 100% correct patients (64 patients), the right medication by (96.9%) (62 patients), and the correct dosage 100% correct (64).


PHARMACON ◽  
2019 ◽  
Vol 8 (2) ◽  
pp. 498
Author(s):  
Febryan Gultom ◽  
Weny I. Wiyono ◽  
Heedy Tjitrosantoso

ABSTRACT Malaria is an infectious disease caused by the Plasmodium parasite (class of Sporozoa) that attacks red blood cells. In indonesia, there are 4 (four) species of malaria parasites, namely Plasmodium falciparum as the cause of tropical malaria which often causes brain malaria with death, Plasmodium vivax as the cause of malaria tertiana, Plasmodium malariae as the cause of malaria quartana and Plasmodium ovale as the cause of ovale malaria. This study aims to determine the patient characteristics and treatment patterns in malaria patients at the inpatient installation of the Mimika District Hospital in period June – December 2018. This study was a descriptive study with retrospective data collection against 68 medical records of malaria patients who were hospitalized inclusion criteria. There were  more men group than women, 41 patiensts (60,29%). Most of malaria patients are in the 0 – 5 year age group with 30 patients (44,12%). The most common type of malaria is uncomplicated vivax malaria 21 patients (33,82%). The most drug use of patients was Primaquin as many as 57 (83,82%) of 68 patients. The exact percentage of drug use for patients is 100%, right drug 89.71%, right dose 92.65%, timely 97.06% and right route 100%. Keywords : Malaria, Drug Utilization Study, Hospitalization.  ABSTRAK Malaria merupakan penyakit menular disebabkan oleh parasit Plasmodium (kelas Sporozoa) yang menyerang sel darah merah. Di Indonesia dikenal 4 (empat) macam spesies parasit malaria yaitu Plasmodium falciparum sebagai penyebab malaria tropika yang sering menyebabkan malaria otak dengan kematian, Plasmodium vivax sebagai penyebab malaria tertiana, Plasmodium malariae sebagai penyebab malaria quartana dan Plasmodium ovale sebagai penyebab malaria ovale. Penelitian ini bertujuan untuk mengetahui karakteristik pasien dan pola pengobatan penyakit malaria pada pasien malaria di instalasi rawat inap RSUD Kabupaten Mimika periode bulan Juni – Desember 2018. Penelitian ini merupakan penelitian deskriptif dengan pengambilan data secara retrospektif terhadap 68 data rekam medik pasien malaria rawat inap yang memenuhi kriteria inklusi. Jumlah pasien laki-laki lebih banyak dibandingkan perempuan yaitu sebanyak 41 pasien (60,29%). Pasien Malaria kebanyakan berada pada kelompok usia 0-5 tahun sebanyak 30 pasien (44,12%). Jenis malaria yang paling sering terjadi adalah Malaria vivax tanpa komplikasi sebanyak 23 pasien (33,82%). Penggunaan obat pasien paling banyak yaitu Primakuin sebanyak 57 (83,82%) dari total 68 pasien. Persentase ketepatan penggunaan obat yang tepat pasien 100%, tepat obat 89,71%, tepat dosis  92.65%, tepat waktu 97,06% dan tepat rute 100%. Kata kunci : Malaria, Studi Penggunaan Obat, Rawat Inap.


2021 ◽  
Vol 1 (1) ◽  
pp. 64-69
Author(s):  
Yayuk Suyudi Rahayu ◽  
Suci Wulandari ◽  
Titi Anjar Pangetsu

Typhoid fever is a systemic infection caused by the salmonella thypi bacteria which attacks the small intestine with fever for 1 week or more accompanied by disturbances in the digestive tract. This disease is endemic and is a community disease that is transmitted through food and drink contaminated with bacteria. Typhoid fever can be treated using antibiotics, giving antibiotics especially in children and infants must consider the side effects on body systems and organ function that are still not perfect. The purpose of this study was to determine the use of ceftriaxone antibiotics based on the right indication, appropriate patient, appropriate medication, proper dosage, timely administration of the drug and the right way of giving antibiotics in the inpatient installation of the Deli Serdang Regional General Hospital in 2019.      This study used retrospective data and was analyzed descriptively by purposive sampling method. Data used by pediatric patients (2-12 years). Data according to the inclusion characteristics of 43 cases were evaluated for their quality based on the right indication, appropriate patient, appropriate medication, proper dosage, the right time of administration and the right way of administration.      The results of this study indicate that the percentage of the quality of antibiotic use includes 43 (100%) right indications, 43 (100%) right patients, 43 (100%) right drugs, 30 (73%) right doses, 42 right time of administration ( 97.67%) and the right way of giving was 43 (100%).


2021 ◽  
Vol 3 (2) ◽  
pp. 47-52
Author(s):  
Yayuk Suyudi Rahayu ◽  
Suci Wulandari ◽  
Titi Anjar Pangestuti

Typhoid fever is a systemic infection caused by the salmonella thypi bacteria which attacks the small intestine with fever for 1 week or more accompanied by disturbances in the digestive tract. This disease is endemic and is a community disease that is transmitted through food and drink contaminated with bacteria. Typhoid fever can be treated using antibiotics, giving antibiotics especially in children and infants must consider the side effects on body systems and organ function that are still not perfect. The purpose of this study was to determine the use of ceftriaxone antibiotics based on the right indication, the right patient, the right drug, the right dose, the right time of administration and the right way of giving antibiotics in the inpatient installation of the Deli Serdang Regional General Hospital in 2019.      This study used retrospective data and was analyzed descriptively by purposive sampling method. Data used by pediatric patients (2-12 years). Data according to the inclusion characteristics of 43 cases were evaluated for their quality based on the right indication, the right patient, the right drug, the right dose, the right time of administration and the right way of administration.      The results of this study indicate that the percentage of the quality of antibiotic use includes 43 (100%) right indications, 43 (100%) right patients, 43 (100%) right drugs, 30 (73%) right doses, 42 right time of administration ( 97.67%) and the right way of giving was 43 (100%).


2020 ◽  
pp. 37
Author(s):  
I Gusti Ayu Nyoman Dyah Sukmawati ◽  
Made Krisna Adi Jaya ◽  
Dewa Ayu Swastini

Typhoid is a global health problem especially in developing countries, one of which is in Indonesia. The incidence of antibiotic resistance in typhoid therapy can occur due to inappropriate use of antibiotics. This study aims to determine patterns of antibiotic use as well as the quality and quantity of antibiotic use in typhoid therapy in one of the provincial government hospitals in Bali. This study was an observational study conducted retrospectively which was analyzed using the Gyssens and ATC/DDD methods. The research data were taken from the medical records of patients in the January-December 2019 period that met the inclusion criteria. The results showed that of the 40 total antibiotics prescribing, ceftriaxone was the most widely used antibiotic for typhoid therapy. The quality of antibiotic use as much as 40% is stated rational (category 0), while the other 60% is irrational (categories I-VI) which includes the use of antibiotics with incorrect interval of administration (IIB; 5%), the use of antibiotics that is too long (IIIA; 40%), the use of antibiotics that are too short (IIIB; 5%), there are other antibiotics that are more effective (IVA; 5%), and there are other antibiotics that are less toxic/safer (IVB; 5%). The quantity of antibiotic use was stated more than WHO standards which includes the use of ceftriaxone at 83.80 DDD/100 patient days; levofloxacin at 27.47 DDD/100 patient days; and azithromycin at 3.52 DDD/100 patient days. The results of this study are expected to be a consideration for the hospital as a material for evaluation and improvement in order to improve the rationality of antibiotic use.


Sign in / Sign up

Export Citation Format

Share Document