scholarly journals TO STUDY THE INCIDENCES OF CARDIAC MANIFESTATION IN THYROID DISORDER (HYPO & HYPER) BOTH IN RURAL AREA OF MALWA REGION

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Dr. Ravija Prasad Ram ◽  
Dr. Divyesh Lad ◽  
Dr. Badri Vishal Singh ◽  
Dr. Arihant Jain
Keyword(s):  
Pulse Pressure ◽  
Sinus Tachycardia ◽  
Heart Sound ◽  
Sinus Bradycardia ◽  
Signs And Symptoms ◽  
Thyroid Disorder ◽  
Diastolic Hypertension ◽  
Prolonged Qt Interval ◽  
Cardiac Manifestation ◽  
Almost All

Background: In this study 100 cases of thyroid dysfunction were studied for the cardiovascular manifestations. Out of these, 60 cases were of hypothyroidism and 40 cases were of hyperthyroidism. There was no age bar for inclusion in the study. All of these cases were selected from those attending the Endocrinology OPD in IMCHRC hospital, Indore. Result: Low pulse pressure is the commonest cardiovascular finding in hypothyroidism (68.33%) followed by diastolic hypertension (55%), soft heart murmur (31.66%), sinus bradycardia (30%) and pericardial effusion (20%) Pulse pressure >40 mm of Hg is the commonest finding in hyperthyroidism. Almost all patients of hyperthyroidism have sinus tachycardia. Conclusion: Study of cardiac signs and symptoms in patient with hyperthyroidism revealed 87.5% prevalence of pulse pressure > 40 mm hg, 85% prevalence of loud heart sound, 82.5% cases of sinus tachycardia, 52.5% cases of hyperdynamic precordium, 47.5% cases of ejection systolic murmur, 42.5% cases of prolonged Qt interval, 25% cases of precordial thrill, 47.5% patients with systolic BP>160 mm Hg, 20 5 cases with mid systolic click, 27.5% patients with LVH , 15% cases with ST-T changes, 5% cases with S3 and 10% patients with atrial fibrillation. Keywords: Cardiac, Manifestation, Thyroid, Hyperthyroidism & Hypothyroidism.

TO STUDY CORRELATION OF CRITERIA LIKE OBESITY, DM, HYPERTENSION, DYSLIPIDEMIA IN RELATION WITH THYROID DISORDER

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Ravija Prasad Ram ◽  
Shivam Sharma ◽  
Manish Kumar Saraf ◽  
Gyanendra Ahirwar
Keyword(s):  
Diabetes Mellitus ◽  
Thyroid Dysfunction ◽  
Thyroid Disorder ◽  
Age Group ◽  
Diastolic Hypertension ◽  
Cardiac Manifestation

Background: In this study 100 cases of thyroid dysfunction were studied for the cardiovascular manifestations. Out of these, 60 cases were of hypothyroidism and 40 cases were of hyperthyroidism. There was no age bar for inclusion in the study. All of these cases were selected from those attending the Endocrinology OPD in IMCHRC hospital, Indore. Result: 78.3% cases of hypothyroidism in our study were suffering from obesity. Relationship between age group and obesity was not significant in these patients. In our study out of 40 patients suffering from hypothyroidism 10 (25%) patients have DM. In our study out of 60 patients suffering from hypothyroidism 28(46.7%) patients were have DM. In our study out of 40 patients of hyperthyroidism, 12 had dyslipidemia. In our study out of 60 patients of hypothyroidism, 41 had dyslipidemia. Conclusion: In our study out of 60 patients suffering from hypothyroidism 28(46.7%) patients were found to have diabetes mellitus. All were females. Out of 60 patients of hypothyroidism, 33 had diastolic hypertension. Out of these 6.1% were male and 93.9% were female. Out of 60 patients of hypothyroidism, 41 had dyslipidemia, of these 97.6% were females only 2.4% were male. Keywords: Cardiac, Manifestation, Thyroid, Hyperthyroidism & Hypothyroidism.

Isolated diastolic hypertension, pulse pressure, and mean arterial pressure as predictors of mortality during a follow-up of up to 32 years

2002 ◽  
Vol 20 (3) ◽  
pp. 399-404 ◽  
Author(s):  
Timo E. Strandberg ◽  
Veikko V. Salomaa ◽  
Hannu T. Vanhanen ◽  
Kaisu Pitkälä ◽  
Tatu A Miettinen
Keyword(s):  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Pulse Pressure ◽  
Predictors Of Mortality ◽  
Diastolic Hypertension

scholarly journals Study of cardiac manifestations in hypothyroid patients admitted in tertiary care centre

2021 ◽  
Vol 8 (12) ◽  
pp. 1852
Author(s):  
Parshv P. Shah ◽  
Harvy Parikh ◽  
Hemant Shah ◽  
Nilesh Doctor
Keyword(s):  
Early Recognition ◽  
Sinus Bradycardia ◽  
Tertiary Care ◽  
General Medicine ◽  
Thyroid Stimulating Hormone ◽  
Hormone Deficiency ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Cardiac Manifestation ◽  
Cardiac Manifestations

Background: Hypothyroidism is the most common pathological hormone deficiency. To study various cardiac manifestations in overt and subclinical hypothyroidism.Methods: The cross-sectional analytic study is carried out on 60 patients of hypothyroid subjects in indoor facility of general medicine department in SMIMER hospital.Results: This study shows positive correlation between thyroid stimulating hormone (TSH) level, electrocardiogram (ECG) and echocardiographic findings. In this study, there is female predominance, ECG findings most commonly suggestive of sinus bradycardia and ECHO findings are most commonly suggestive of diastolic dysfunction with pericardial effusion.Conclusions: The early recognition and early initiation of treatment of hypothyroidism may helpful to lowering heart changes as hypothyroidism is reversible cause for cardiac manifestation.

scholarly journals A randomized trial evaluating the safety profile of sugammadex in high surgical risk ASA physical class 3 or 4 participants

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
W. Joseph Herring ◽  
Yuki Mukai ◽  
Aobo Wang ◽  
Jeannine Lutkiewicz ◽  
John F. Lombard ◽  
...  
Keyword(s):  
Sinus Tachycardia ◽  
Sinus Bradycardia ◽  
Neuromuscular Block ◽  
Tolerability Profile ◽  
Double Blind ◽  
Link Type ◽  
Cardiac Arrythmias ◽  
Deep Neuromuscular Block ◽  
American Society ◽  
The Impact

Abstract Background The aim of this randomized, double-blind trial was to evaluate the safety and tolerability profile, including cardiac safety, of sugammadex-mediated recovery from neuromuscular block in participants undergoing surgery who met the American Society of Anesthesiologists (ASA) Physical Class 3 or 4 criteria. Specifically, this study assessed the impact of sugammadex on cardiac adverse events (AEs) and other prespecified AEs of clinical interest. Methods Participants meeting ASA Class 3 and 4 criteria were stratified by ASA Class and NMBA (rocuronium or vecuronium) then randomized to one of the following: 1) Moderate neuromuscular block, sugammadex 2 mg/kg; 2) Moderate neuromuscular block, neostigmine and glycopyrrolate (neostigmine/glycopyrrolate); 3) Deep neuromuscular block, sugammadex 4 mg/kg; 4) Deep neuromuscular block, sugammadex 16 mg/kg (rocuronium only). Primary endpoints included incidences of treatment-emergent (TE) sinus bradycardia, TE sinus tachycardia and other TE cardiac arrhythmias. Results Of 344 participants randomized, 331 received treatment (61% male, BMI 28.5 ± 5.3 kg/m2, age 69 ± 11 years). Incidence of TE sinus bradycardia was significantly lower in the sugammadex 2 mg/kg group vs neostigmine/glycopyrrolate. The incidence of TE sinus tachycardia was significantly lower in the sugammadex 2 and 4 mg/kg groups vs neostigmine/glycopyrrolate. No significant differences in other TE cardiac arrythmias were seen between sugammadex groups and neostigmine/glycopyrrolate. There were no cases of adjudicated anaphylaxis or hypersensitivity reactions in this study. Conclusions Compared with neostigmine/glycopyrrolate, incidence of TE sinus bradycardia was significantly lower with sugammadex 2 mg/kg and incidence of TE sinus tachycardia was significantly lower with sugammadex 2 mg/kg and 4 mg/kg. These results support the safety of sugammadex for reversing rocuronium- or vecuronium-induced moderate and deep neuromuscular block in ASA Class 3 or 4 participants. Trial registration ClinicalTrials.gov Identifier: NCT03346057.

Meningitis—What Is It?

2019 ◽  
pp. 1-22
Author(s):  
Janet R. Gilsdorf
Keyword(s):  
Cerebrospinal Fluid ◽  
Young Children ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Pathologic Examination ◽  
Helen Keller ◽  
Clinical Signs And Symptoms ◽  
Almost All

Before the advent of antibiotics, meningitis was a dreadful infection by any standard; many of its victims were young children, and almost all died, succumbing to the disease from days to six weeks, or sometimes longer, after the onset of their illness. Incredibly, patients occasionally survived but were often left with varying degrees of neurologic damage. Before the first spinal tap, the diagnosis of meningitis was based on clinical signs and symptoms and could be confirmed only by pathologic examination of the brains of deceased patients during an autopsy. Since the advent of the spinal tap, the diagnosis of meningitis rests on examination of the cerebrospinal fluid. Treatment of meningitis depends on which bacteria cause the infection. Helen Keller may be a famous surviving victim of this disease.

Sinus Bradycardia and Sinus Tachycardia

2011 ◽  
Vol 31 (2) ◽  
pp. 75-79
Author(s):  
Darlene Hutton
Keyword(s):  
Sinus Tachycardia ◽  
Sinus Bradycardia

scholarly journals GUILLIAN BARRE SYNDROME;

2019 ◽  
Vol 26 (02) ◽  
Author(s):  
Shahid Iqbal ◽  
Naeemullah Bullo ◽  
Dileep Kumar ◽  
Suneel Kumar ◽  
Munir Afzal ◽  
...  
Keyword(s):  
Clinical Features ◽  
Sinus Tachycardia ◽  
Sinus Bradycardia ◽  
Tertiary Care ◽  
Care Hospital ◽  
Inclusion Criteria ◽  
Control Effect ◽  
Study Results ◽  
Data Analysis Procedure ◽  
Tertiary Care Hospitals

Objectives: To determine the frequency of various clinical features of Guillian Barre Syndrome in patients presenting to a tertiary care hospital in Karachi. Study Design: Descriptive study. Period: July 2015 to December 2015. Setting: Tertiary care hospitals of Karachi. Material & Methods: Seventy five diagnosed case of GBS who fulfill the inclusion criteria irrespective of gender included in the study after informed consent. Data was collected on preformed proforma. Detailed history, physical examination was done on each patient, diagnosis was confirmed on NCV & EMGs.  Data analysis procedure was done with the help of SPSS version 16. Mean±SD was calculated for age of the patient and duration of clinical features. Frequency and percentages were calculated for different clinical features. Stratification was done with respect to age, gender and duration of clinical features to control effect modifiers in the study. Results: Mean age was 43.96±14.22 (ranging from 15 to 70) years, among 75 patients 51(68%) were male & 24(32%) were female, majority of patients (34) were >50 years of age, 45.3% of patients had pain in extremities; pain in back was reported by 49.3%. Dysphagia in 80%, Ophthalmoplegia in 20% and Dysarthria in 16% of patients Respiratory failure was prevalent in 34.7% patients. Sinus tachycardia occurred in 49.3%, Sinus bradycardia 14.7% patients and 20% patients had urinary dysfunction. Constipation was also a predominant feature affecting 80% of patients. Conclusion: We found that GBS occurred at all ages and was more common in males. There are various clinical features of GBS along with flaccid limbs weakness clinical features observed & these should be address promptly for better outcome.

scholarly journals Incidence of scrub typhus in a tertiary care hospital in Kolkata, India

2020 ◽  
Vol 7 (5) ◽  
pp. 825
Author(s):  
Kausik Munsi ◽  
Sayonee Das ◽  
Ramiz Islam ◽  
Parvez Shahide Biswas ◽  
Satyabrata Ganguly ◽  
...  
Keyword(s):  
Scrub Typhus ◽  
Tertiary Care ◽  
Febrile Illness ◽  
Signs And Symptoms ◽  
Care Hospital ◽  
Female Ratio ◽  
Gi Symptoms ◽  
Ns1 Antigen ◽  
Morbilliform Rash ◽  
Almost All

Background: Authors aimed to identify incidence of scrub typhus among patients of fever. Scrub typhus is an endemic disease in India caused by Orientia tsutsugamushi, transmitted by trombiculid mites. It is an important cause of acute febrile illness in India. Signs and symptoms include fever, headache, myalgia and GI symptoms and is generally associated with morbilliform rash (<40%), eschar (<50%) which is due to bite of the mite. Abnormal LFTs and lymphocytosis are commonly seen in early phase of illness. It’s often labelled as PUO. Early diagnosis and prompt administration of therapy mostly leads to complete recoveryMethods: Authors screened 100 patients presenting with fever, malaise, headache, with or without rash for more than a week from the month of May to December 2019. Routine blood investigations with fever profile (Dengue NS1 antigen, MP, MPDA, TyphidotM) and cultures were done. Patients in whom no cause of fever could be established, having lymphocytosis, hyponatremia and transaminitis, they were tested for Scrub typhus by using Indirect immunofluorescence & detection of IgM antibody.Results: Total 22 patients were found positive for scrub typhus by using the aforementioned method (22%). Male: Female ratio was 3:4 (9 vs 12). Patients were in the age group of 16-76 years. Lymphocytosis, hyponatremia and transaminitis were cardinal features seen in almost all patients diagnosed with Scrub Typhus.Conclusions: This study will help clinicians to have a stronger suspicion of scrub typhus in undiagnosed febrile patients.

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