scholarly journals CORRELATION OF PAP SMEAR AND COLPOSCOPIC FINDING WITH DIRECTED BIOPSY TO ASSESS THE ADVANTAGE OF CONCURRENT TESTING BY CYTOLOGY AND COLPOSCOPY IN THE DETECTION OF CERVICAL NEOPLASM

2021 ◽  
Vol 5 (11) ◽  
Author(s):  
Diksha Kumari Chittara ◽  
Suman Mendiratta ◽  
Anil Gurjar
Keyword(s):  
Cervical Cancer ◽  
Pap Smear ◽  
Exclusion Criteria ◽  
Cervical Neoplasm ◽  
Poor Countries ◽  
Medical College ◽  
Obstetrics And Gynaecology ◽  
Concurrent Testing ◽  
Study Participants

Background: Cervical cancer was the second most common cancer among women 15-44 years of age and in 2018 it was the fourth most frequent cancer and cause of cancer death among all women in the world Methods:Women (18-65 yrs) attending Department of Obstetrics and Gynaecology, SMS Medical College, Jaipur were recruited for study. After applying inclusion and exclusion criteria written and informed consent were taken from all study participants Results: On histopathology report we found that 10% had normal inflammation followed by 9.33% had carcinoma in situ, 8% had CIN-2, 6.67% had CIN-1, 5.67% had CIN-3 and Squamous cell carcinoma each. Conclusion: Pap smear and colposcopy both the tests can be used to complement each other in a hospital based screening programme, where facilities for both modalities are available. Hence use of single visit approach in which cytology, colposcopy and guided biopsy all are done in single sitting, and treated accordingly in resource poor countries like ours will enable maximal utilization of scarce medical resources. Keywords: Pap smear, CIN, Cervical cancer

scholarly journals Diagnostic Modalities of Precancerous and Cancerous Cervical Lesions with Special Emphasis on CD31 Angiogenesis Factor as a Marker

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Bandana Sharma ◽  
Neetu Singh ◽  
Neena Gupta ◽  
Pavika Lal ◽  
Shefali Pande ◽  
...  
Keyword(s):  
Statistical Analysis ◽  
Pap Smear ◽  
Histopathological Examination ◽  
Cervical Lesions ◽  
Invasive Group ◽  
Angiogenesis Factor ◽  
Medical College ◽  
Obstetrics And Gynaecology ◽  
Diagnostic Modalities

Objectives. To evaluate the role of angiogenesis tumor marker CD31 in the detection of precancerous and cancerous cervical lesions and to compare its efficacy with colposcopy and histopathology. Materials and Methods. 230 patients with a suspicious looking cervix and an abnormal Pap smear attending the Outpatient Department of Obstetrics and Gynaecology of GSVM Medical College were subjected to a colposcopic examination. 180 patients with suspected colposcopic findings were subjected to a colposcopic directed biopsy. Biopsy tissues were sent for histopathological examination out of which 50 biopsied samples were sent for immunostaining of CD-31. Statistical analysis was done. Results. Comparison of microvessel density (MVD) count by haematoxylin and eosin staining (HE) and immunostaining of CD31 in preinvasive group were and , respectively, and in invasive group were and , respectively, which showed that MVD was higher by CD31 both in preinvasive and invasive group, and it was statistically significant. Conclusion. Angiogenesis is a marker of tumor progression, and CD31 fixes up vessel better as compared to HE, so aggressiveness of the tumor can be better predicted by MVD-CD31 as compared to MVD-HE.

scholarly journals AN INTERVENTIONAL STUDY TO ASSESS THE CYTOLOGICAL AND COLPOSCOPIC CHANGES AFTER INTRAUTERINE CONTRACEPTIVE DEVICES INSERTION IN THE DEPARTMENT OF OBSTETRICS GYNAECOLOGY, SMS MEDICAL COLLEGE, JAIPUR

2021 ◽  
Vol 5 (7) ◽  
Author(s):  
Mamta Prajapat ◽  
Suniti Verma ◽  
R N Sehra ◽  
Jyoti Saini
Keyword(s):  
Trichomonas Vaginalis ◽  
Pap Smear ◽  
Medical College ◽  
Contraceptive Devices ◽  
Exfoliated Cells ◽  
Increased Risk ◽  
Intrauterine Contraceptive ◽  
Long Term Follow Up

Background: Cytology examines exfoliated cells, while colposcopy examines the changes that occur in the vascular structure of the cervix5. Patients with an abnormal pap smear result or patients with a suspicious-looking cervix even if they had a negative pap smear, should be evaluated by colposcopy and colposcopy directed biopsy. Methods: Interventional Prospective study conducted at Department of Obstetrics and Gynaecology, SMS Medical College & associated Hospitals, Jaipur. Results: In this study, among 15 IUCD users, 5 (33.33%) had bacterial vaginosis, 2 (13.33%) had trichomonas vaginalis and 1 (6.66%) were found candidal infection, 1 (6.66%) polymicrobial infection. Conclusion: The present study indicates that there is definite changes in the cervical architecture in IUCD users and the change is also dependent on the duration of use. A simple technique like cytology and colposcopy is highly useful in diagnosing these changes and combating them by early interference whenever necessary. The present study does not reveal any increased risk of cervicitis and dysplasia in IUCD users. We further recommend that a long term follow-up is required to rule out the possibility of any increased risk of dysplasia or carcinoma in-situ. Keywords: IUCD, Colposcopy, Dysplasia.

scholarly journals Kisspeptin: new biomarker of pregnancy

2019 ◽  
Vol 8 (8) ◽  
pp. 3021
Author(s):  
Priyanka Meena ◽  
Rati Mathur ◽  
Mohan L. Meena
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Positive Relationship ◽  
Elisa Method ◽  
Medical College ◽  
Obstetrics And Gynaecology ◽  
Study Participants ◽  
Relationship Of ◽  
The Relationship ◽  
Single Blood Sample

Background: The recently identified hormone kisspeptin has been suggested to play an important regulatory role in placentation. The aim and objective of the study is the measurement of serum kisspeptin level in asymptomatic pregnant women and to find out the association of serum kisspeptin with gestational age in women with early pregnancy.Methods: This was a longitudinal study to the evaluation of 178 asymptomatic pregnant women with a gestation of 6 to 16 weeks attending routine antenatal booking visit recruited as study participants from the Antenatal Clinical of Obstetrics and Gynaecology Department, S.M.S. Medical College and Attached Hospitals, Jaipur, Rajasthan, India.Results: After initial clinical examination of every participant, a single blood sample was taken for the measurement of serum kisspeptin. Serum kisspeptin measurement test was performed by ELISA method and results were expressed as ng/ml. Pregnancy outcome was recorded prospectively. Mean serum kisspeptin level of study participants was 2.80±1.87ng/ml and median were 2.41 (Range 0.244-14.06ng/ml). Our result showed the relationship of serum kisspeptin with gestational age (GA) (p<0.000).Conclusions: serum kisspeptin level increases in pregnancy and showed positive relationship with gestational age significantly (p<0.000).

scholarly journals Breakthroughs and Issues in HPV Genital Infections in relation to Cervical Cancer

2012 ◽  
Vol 1 (2) ◽  
pp. 27-30
Author(s):  
Farhat Hussain ◽  
Khairun Nahar ◽  
Kaniz Fatema ◽  
Mahbuba Khan
Keyword(s):  
Cervical Cancer ◽  
Pap Smear ◽  
Pap Test ◽  
Cervical Cancer Prevention ◽  
Cervical Lesions ◽  
Related Condition ◽  
Papilloma Virus ◽  
Medical College ◽  
Hpv Test ◽  
Neoplastic Process

The field of cervical cancer prevention is rapidly evolving because of identification of the cause of disease. Human Papilloma Virus (HPV) has been recognized as a necessary cause of cervical cancer, and the association applies equally to both squamous cell and adenocarcinoma and is consistent worldwide. HPV 16 and 18 together attribute 70% of world's cervical cancer. HPV is highly prevalent among sexually active women and traceable in its natural history with technology that can detect HPV DMA at all stages of infection and neoplastic process. HPV DMA testing represents the scientifically obvious next step after Pap test for secondary prevention. A clinically validated and FDA approved HPV test has proven a substantial gain in sensitivity with a limited loss in speciality as compared to the standard Pap smear. We are now in the fortunate position of having two highly promising HPV vaccines in the pipeline. These vaccines today represent new hope for protection against cervical cancer, pre-cancerous cervical lesions and other HPV related condition for the current generation of adolescents, for the young and middle aged women as well as for the future generations. DOI: http://dx.doi.org/10.3329/jssmc.v1i2.12163 Journal of Shaheed Suhrawardy Medical College Vol.1, No.2, December 2009 p.27-30

scholarly journals Uterine Cervical Neoplasm Diagnosed by Flexible Magnifying Endoscopy with Narrow Band Imaging

Diagnostics ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 903
Author(s):  
Hideki Kobara ◽  
Kunihisa Uchita ◽  
Noriya Uedo ◽  
Noriko Matsuura ◽  
Noriko Nishiyama ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Pap Smear ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Early Stage ◽  
Magnifying Endoscopy ◽  
Diagnostic Tools ◽  
Gastrointestinal Neoplasms ◽  
Cervical Neoplasm ◽  
Uterine Cervical Neoplasm

When detected early, uterine cervical cancer is one of the most successfully treatable forms of cancer. The diagnostic accuracy of the standard method, the Pap smear test followed by colposcopy, remains unsatisfactory. To improve detection of early-stage cervical cancer, new diagnostic tools for uterine cervical intraepithelial neoplasm (CIN) need to be developed. Magnifying endoscopy with narrow- band imaging (ME-NBI), which allows the visualization of the micro-structure as well as micro-vascularity of the mucosal surface, has excellent diagnostic ability for early gastrointestinal neoplasms. In our previous investigation, ME-NBI was efficacious for diagnosis of CIN. We herein report two notable cases of CIN3 that were diagnosed by ME-NBI that were not detected by colposcopy. These cases illustrate the usefulness of ME-NBI for diagnosis of early-stage uterine cervical neoplasms.

scholarly journals TO STUDY THE PATTERN OF VARIOUS CERVICAL LESION

2021 ◽  
Vol 5 (7) ◽  
Author(s):  
Seema Gupta ◽  
Deepali Jain ◽  
Shweta Khandelwal
Keyword(s):  
Cervical Cancer ◽  
Retrospective Study ◽  
Health Problem ◽  
Pap Smear ◽  
Early Stage ◽  
Medical College ◽  
Efficient Management ◽  
Cellular Changes ◽  
Malignant Lesions ◽  
Cancer Of The Cervix

Background: Cancer of the cervix is an increasing health problem and an important cause of mortality in women worldwide. The incidence of cervical cancer arises worldwide. Methods: A retrospective study was conducted in the Department of Pathology, JLN Medical College & Hospital Ajmer. Results: A total of 100 smears were analyzed. Out of which 96.00% smears were satisfactory for evaluation.  Out  of 96.00% satisfactory smears, 30.00% shows normal smear and 52.00% shows benign cellular changes and 4.00% shows epithelial cells abnormality. 5.00% smears shows Bacterial vaginosis. 45.00% were inflammatory smears. Conclusion: We concluded that cervical cytology by Pap smear is a simple, safe and effective test to detect premalignant and malignant lesions of cervix at an early stage, and thus help the clinicians in early and more efficient management of the patients. Keywords: Pap smear, Cervix, Cytology.

scholarly journals Knowledge and Awareness of Cervical Cancer and Screening Practices among Nurses at Lahore General Hospital, Pakistan

2020 ◽  
pp. 7-12
Author(s):  
Nazia Ayub ◽  
Mahliqa Maqsud ◽  
Huma Tahseen ◽  
Mehmona Sharif ◽  
Nahid Waris ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
General Hospital ◽  
Pap Smear ◽  
Reproductive Age ◽  
Early Marriage ◽  
Age Group ◽  
Cross Sectional ◽  
Screening Practices ◽  
Abnormal Growth ◽  
Study Participants

Objective: To find out the knowledge, awareness and screening practices of cervical cancer among nurses at Lahore general Hospital, Lahore, Pakistan. Materials and Methods: This cross-sectional, interview based study was conducted on 250 nurses at Lahore general Hospital, Lahore, Pakistan. The duration of this study was one year from 2017 to 2018. All the cases underwent interview based information regarding cervical cases. The questionnaire was applied to assess the knowledge, awareness and screening practices about cervical cancer among nurses. Data was collected via self-made proforma. Results: Most of the study participants were less than 35 years. 72% nurses were married and 28% were married. Most of the study participants 96% known that cervical cancer is the abnormal growth of cervical cells and few were unaware regarding it. According to causes of cervical cancer, 70% to 75.6% participants agreed with the causes of early marriage and multiple sex partners, while others had ideas of smoking, infection and hereditary causes. 25.5% nurses answered that it can occur in any age group, 11.2% replied in reproductive age group, 42.8% were agreed with menopausal age group and 20.4% had no idea. 75.6% to 95.5% nurses were in the favor of scanning, pap smear test and cervical biopsy methods. 85 participants said it is a preventable disease via vaccination, early diagnosis and safe sex activities. Conclusion: It was concluded that nurses had satisfactory knowledge and screening practice cervical cancer at Lahore general Hospital.

scholarly journals Knowledge attitude and practices about cervical cancer among urban women working in BPO in Chennai, India

2021 ◽  
Vol 8 (3) ◽  
pp. 1252
Author(s):  
Nilofur Banu ◽  
Azarudheen S.
Keyword(s):  
Cervical Cancer ◽  
Tamil Nadu ◽  
Pap Smear ◽  
Hpv Vaccination ◽  
Urban Women ◽  
Vital Role ◽  
Common Source ◽  
Cross Sectional ◽  
Attitudes And Practices ◽  
Study Participants

Background: Worldwide cervix cancer ranks fourth place among all the cancer affecting women and commonest cause of death due to cancer among women in developing countries. Business process outsourcing sector in India is a relatively new industry with each growth there is also various negative health issue emerge among people working in those sectors some risk factors associated with ca cervix. Aim of the study was to knowledge, attitudes and practices (KAP) toward cervical cancer, HPV vaccination and screening practice among urban women working in BPO in Chennai.Methods: A cross sectional study was conducted among urban women working in a BPO in Chennai, Tamil Nadu. A face-to-face interview was conducted using a structured questionnaire by the team leader who was train to interview before starting the study.Results: Among 155 female study participants only 46% of the respondents knew about cervix. Among the study participants who knew about cervix and cervical cancer, internet (26%) and TV/Radio (26%) were the most common source of information. Only 4% of respondent heard of Pap smear and none of them had undergone it. Similarly, only 3.73% of the respondents knew about vaccines that are available for Cancer Cervix.Conclusions: The findings of study will help us in planning focused health measures about CA cervix and its prevention strategies .Health awareness will play a vital role in reducing risks of casualties caused by diseases like cancer Cervix.

STUDY AND ANALYSIS OF CERVICAL PAP SMEARS IN A MEDICAL COLLEGE HOSPITAL

2021 ◽  
pp. 31-33
Author(s):  
S. Preetika ◽  
Sahayaraj Sahayaraj
Keyword(s):  
Cervical Cancer ◽  
Pap Smear ◽  
Age Groups ◽  
Pap Test ◽  
Developed Countries ◽  
Pap Smears ◽  
Cervical Lesions ◽  
College Hospital ◽  
Medical College ◽  
Pap Smear Screening

Introduction: Cervical cancer is the second most common gynaecological cancer worldwide and the third leading cause of cancer-related mortality in the less developed countries. Cervical cancer may be prevented or diagnosed at early stages due to the easy accessibility and clinical evaluation of the cervix. A pap test is a simple, easy, painless procedure which can be carried out as an outpatient procedure to detect specic, nonspecic inammations, precancerous and cancerous lesions In our study we have analysed the results of PAP smears of women in all age groups and have tried to evaluate the prevalence of cervical lesions and the importance of cervical cancer screening. Material And Methods: Our study was conducted between October 2020 to JULY 2021 and patients who have visited the Gynaec OP during this period were included for this study. We received Pap smears from the Department of Obstetrics and Gynecology, stained the slides with Pap stain and studied the smears according to the new Bethesda System for Reporting Cervical Cytology 2014. Results: In our study, majority of the patients were in the age group of 41-50 years. Smears showing ASCUS were 14 , LSIL reports were 5, HSIL reports were 4. No Smears showed squamous cell carcinoma in our study. Reports in our study like many other studies has shown the importance of Pap smear test in screening cervical cancer. By conducting health camps, increasing health awareness and performing Pap smear screening programmes the incidence of cervical carcinoma can be decreased.

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