scholarly journals Clinical Findings and Risk Factors of COVID-19 Infection and Death in Elderly patients Admitted to Medical Centers of Mazandaran University of Medical Sciences During 1 Year

Salmand ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. 128-139
Author(s):  
Zoya Hadinejad ◽  
◽  
Yahya Saleh Tabari ◽  
Zeinab Sajadi ◽  
Hassan Talebi Ghadicolaei ◽  
...  
Keyword(s):  
Risk Factors ◽  
Kidney Diseases ◽  
Oldest Old ◽  
The Elderly ◽  
Clinical Findings ◽  
Age Group ◽  
Medical Sciences ◽  
Risk Of Death ◽  
Descriptive Research ◽  
Medical Centers

Objectives: The elderly are at higher risks for developing Coronavirus Disease 2019 (COVID-19). Besides, when generating the illness, they have a higher risk of death. Recognizing clinical characteristics and risk factors associated with morbidity and mortality in the elderly is necessary to prevent mortality in similar infectious diseases. Methods & Materials: This descriptive research explored the data of all geriatrics admitted following COVID-19 in the medical centers affiliated with Mazandaran University of Medical Sciences. These data were collected from February 20, 2020, to February 20, 2021. Data analysis was performed by SPSS using logistic regression analysis. P<0.05 was considered significant. Results: Of the total 54523 patients admitted to the medical centers in the 12 months, 25218 patients were elderlies. In total, 51.05% and 12343 of the patients were female and male, respectively. In total, 3512 elderlies were expired. The death cases included 1814 (51.65%) males and the rest were females. Moreover, 16203 patients were in the age group of youngest-old, aged 60-75 years; 8270 patients were middle-old, 76-90 years; and the oldest-old category included 745 patients in the age group of ≥90 years. There was a significant relationship between age, gender, and COVID-19-induced death in the elderly (P<0.05). Older adults presented the highest death rate due to this disease Men were 10% more prone to die from COVID-19 than women. Major comorbidities recorded in this population were kidney diseases (92%), cancer (76%), diabetes (32%), and cardiovascular diseases (17%). Conclusion: Preventive measures to support the elderly are essential to combat the COVID-19 pandemic. Furthermore, it is essential to focus on the specific health needs of the elderly, such as proper nutrition, wellbeing, and mental health promotion.

Abstract P614: Effect Sizes of Vascular Risk Factors for Stroke Occurrence by Age Among West Africans

Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Mayowa Owolabi ◽  
FRED S SARFO ◽  
Onoja Akpa ◽  
Joshua Akinyemi ◽  
Albert Akpalu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Middle Age ◽  
Meat Consumption ◽  
The Elderly ◽  
Vascular Risk Factors ◽  
Effect Sizes ◽  
Modifiable Risk Factors ◽  
Age Group ◽  
Vascular Risk ◽  
Elderly Age

Background: Age is a non-modifiable risk factor for stroke occurrence due its influence on vascular risk factor acquisition. In sub-Saharan Africa, the effect sizes of vascular risk factors for stroke occurrence by age is unknown. Objective: To quantify the magnitude and direction of the effect sizes of key modifiable risk factors of stroke according to three age groups: <50years(young), 50-65 years(middle age) and >65 years(elderly) in West Africa. Methods: The Stroke Investigative Research and Educational Network (SIREN) is a multicenter, case-control study involving 15 sites in Ghana and Nigeria. Cases include adults aged ≥18 years with evidence of an acute stroke. Controls were age-and-gender matched stroke-free adults. Detailed evaluations for vascular, lifestyle, stroke severity and outcomes were performed. We used conditional logistic regression to estimate adjusted odds ratios (aOR) of vascular risk factors of stroke. Results: Among 3,553 stroke cases, 813(22.9%) were young, 1441(40.6%) were middle-aged and 1299(36.6%) were elderly. Five modifiable risk factors were consistently associated with stroke occurrence regardless of age namely hypertension, dyslipidemia, diabetes mellitus, regular meat consumption and non-consumption of green vegetables. Among the 5 co-shared risk factors, the effect size, aOR(95%CI) of dyslipidemia, 4.13(2.64-6.46), was highest among the young age group, hypertension, 28.93(15.10-55.44) and non-consumption of vegetables 2.34(1.70-3.23) was highest among the middle-age group while diabetes, aOR of 3.50(2.48-4.95) and meat consumption, 2.40(1.76-3.26) were highest among the elderly age group. Additionally, among the young age group cigarette smoking and cardiac disease were associated with stroke. Furthermore, physical inactivity and salt intake were associated with stroke in the middle-age group while cardiac disease was associated with stroke in the elderly age group. Conclusions: Age has a profound influence on the profile, magnitude and direction of effect sizes of vascular risk factors for stroke occurrence among West Africans. Population-level prevention of stroke must target both co-shared dominant risk factors as well as factors that are unique to specific age bands in Africa.

scholarly journals MDCT evaluation of coronary artery calcification in Nepalese population undergoing CT thorax examination for non-cardiac pathology

2014 ◽  
Vol 6 (4) ◽  
pp. 40-44
Author(s):  
Mukesh Kumar Gupta ◽  
Raj Kumar Rauniyar ◽  
Naveen Kumar Pandey ◽  
Deepak Kumar Yadav
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Cross Sectional Study ◽  
Age Group ◽  
Medical Sciences ◽  
Cross Sectional ◽  
Cardiac Pathology ◽  
Patients With Diabetes ◽  
Ct Evaluation ◽  
Atherosclerotic Risk Factors

Background:Coronary artery calcification (CAC) is frequently encountered as incidental findings during CT evaluation of thorax; however, little is known about its magnitude and association with atherosclerotic risk factors in Nepalese population. The purpose of this study was to evaluate the frequency of incidental CAC in patients undergoing standard thoracic CT examination for non-cardiac pathology and to correlate it with risk factors for coronary atherosclerosis.Methods: A hospital based prospective cross-sectional study was conducted on 216 patients over 8 month duration. The coronary arteries were evaluated for calcification on 16-slice MDCT and the frequency of CAC was correlated with atherosclerotic risk factors viz. age, sex, diabetes mellitus, hypertension, smoking and obesity.Results: Incidental CAC was seen in 72(33.3%) of total 216 patients. The rates of CAC below 40, 40-60 and above 60 years age group were 0%, 31.6% and 43.9% respectively. The frequency of CAC in male and female were 35% and 31.2% for all ages, 43.6% and 20% for 40-60 years group, and 35.2% and 61.1% for above 60 years age group respectively. The frequency of CAC was higher in patients with diabetes mellitus (47.5%), hypertension (42.3%), smoking (43%) and obesity (38.9%).Conclusion: Incidental CAC was seen in 33.3% of the patients and it had significant association with advancing age, diabetes mellitus, hypertension and smoking. Rate of CAC was significantly higher in male for 40-60 years group but the frequency drastically increased in female for above 60 years group. DOI: http://dx.doi.org/10.3126/ajms.v6i4.11205 Asian Journal of Medical Sciences Vol.6(4) 2015 40-44

scholarly journals The Influence of Pain on Frailty among the Elderly: Based on Korea Health Panel

2020 ◽  
Author(s):  
Sun Mi SHIN
Keyword(s):  
Economic Activity ◽  
Physical Inactivity ◽  
Daily Life ◽  
Oldest Old ◽  
The Elderly ◽  
Age Group ◽  
Odds Ratios ◽  
Prevalence Of Pain ◽  
Mobility Reduction ◽  
Extreme Pain

Background: Interests between pain and frailty have been increasing in aging or aged societies. This study aimed to identify the prevalence of pain and frailty and to find the influence of pain on frailty. Methods: Subjects were selected with aged 65 yr or older among pooled Korea Health Panel data from 2009 to 2013. The prevalence of pain was determined by combining some pain and extreme pain and also, frailty was defined when subjects had at least one of the following 6-domain frailty: physical inactivity, mobility reduction, dependence of daily life, depression, multimorbidity, and disability. Results: The prevalence of pain and frailty was 56.1% and 59.8%. It was significantly higher in female (66.1% and 65.2%) and the oldest-old (69.4% and 71.8%). After adjusting for gender, age group, spouse, illiteracy, and economic activity, odds ratios of frailty for some pain and extreme pain were 2.8 (95% CI 2.6-3.0) and 10.5 (95% CI 8.0-13.8) in total subjects. The odds ratios of each 6-domain frailty for some and extreme pain were also significant. Among them, mobility reduction was 5.1 (95% CI 4.5-5.8) and 16.5 (95% CI 13.6-20.1), and dependence of daily life was 3.9 (95% CI 3.5-4.5) and 12.4 (95% CI 10.2-15.1). Conclusion: Among the elderly, prevalence of frailty (59.8%) was somewhat higher than that of pain (56.1%). Female and oldest-old had higher prevalence of pain and frailty. In addition, some pain and extreme pain had a decisive influence on frailty and each 6-domain frailty. Therefore, pain control is essential to prevent or manage frailty.

scholarly journals Comparing the Clinical Characteristics and Mortality of Residential and Non-Residential Older People with COVID-19: Retrospective Observational Study

2022 ◽  
Vol 19 (1) ◽  
pp. 483
Author(s):  
Francesc X. Marin-Gomez ◽  
Jacobo Mendioroz-Peña ◽  
Miguel-Angel Mayer ◽  
Leonardo Méndez-Boo ◽  
Núria Mora ◽  
...  
Keyword(s):  
Risk Factors ◽  
Electronic Medical Records ◽  
Medical Records ◽  
Clinical Characteristics ◽  
Fold Increase ◽  
The Elderly ◽  
Health Administration ◽  
Epidemic Outbreak ◽  
Risk Of Death ◽  
Using Data

Nursing homes have accounted for a significant part of SARS-CoV-2 mortality, causing great social alarm. Using data collected from electronic medical records of 1,319,839 institutionalised and non-institutionalised persons ≥ 65 years, the present study investigated the epidemiology and differential characteristics between these two population groups. Our results showed that the form of presentation of the epidemic outbreak, as well as some risk factors, are different among the elderly institutionalised population with respect to those who are not. In addition to a twenty-fold increase in the rate of adjusted mortality among institutionalised individuals, the peak incidence was delayed by approximately three weeks. Having dementia was shown to be a risk factor for death, and, unlike the non-institutionalised group, neither obesity nor age were shown to be significantly associated with the risk of death among the institutionalised. These differential characteristics should be able to guide the actions to be taken by the health administration in the event of a similar infectious situation among institutionalised elderly people.

Prevalence of Cardiovascular Risk Factors in the Elderly Population of Alentejo

2020 ◽  
pp. 185-195
Author(s):  
Maria do Céu Mendes Pinto Marques ◽  
Ana Filipa Pereira Vaz ◽  
Ana Sofia Emídio Cardoso Leite ◽  
Cláudia Sofia Araújo ◽  
Cláudia Roque Condeço ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Elderly Population ◽  
Research Question ◽  
National Level ◽  
The Elderly ◽  
Regional Level ◽  
Age Group ◽  
Prevalence Studies

The objective of this chapter is to identify cardiovascular risk factors in the elderly and their prevalence in the elderly population of Alentejo. The research question was elaborated according to the PI[C]OD methodology. The prevalence studies included allow the authors to identify the risk factors with the greatest impact on cardiovascular diseases, with the analysis of at least one of the factors (hypertension, diabetes, smoking, obesity, hypercholesterolemia, alcoholism, and sedentary lifestyle) and their prevalence in the elderly from the region of Alentejo. The results present the prevalence of cardiovascular risk factors, mainly at the national level, compared to those at the regional level, with a small number of exclusive studies in the Alentejo region, while simultaneously disaggregating the results by age group. From the data obtained, it can be concluded that the prevalence of risk factors is generally increased in the elderly population and, consequently, in Alentejo, because it is a region in the interior of the country that is predominantly rural and very old.

scholarly journals Prevalence and risk factors of pulmonary nontuberculous mycobacterial infections in the Zhejiang Province of China

2019 ◽  
Vol 147 ◽  
Author(s):  
Jintian Xu ◽  
Ping Li ◽  
Shengchao Zheng ◽  
Wei Shu ◽  
Yu Pang
Keyword(s):  
Risk Factors ◽  
Reference Group ◽  
The Elderly ◽  
Zhejiang Province ◽  
Age Group ◽  
Pulmonary Tb ◽  
History Of ◽  
Normal University ◽  
The Difference ◽  
Culture Positive

Abstract Risk factors and prevalence of pulmonary nontuberculous mycobacterial (NTM) diseases were retrospectively evaluated in 1208 suspected pulmonary TB patients seeking care at the Affiliated Hospital of Hangzhou Normal University between July 2018 and December 2018. Further analysis of 390 culture-positive cases demonstrated that 358 (358/390, 91.8%) were infected with Mycobacterium tuberculosis (MTB), 24 (24/390, 6.2%) with NTM and eight (8/390, 2.0%) with both MTB and NTM. M. intracellulare was the most prevalent NTM isolated (16/24, 66.7%), followed by M. abscessus (3/24), M. kansasii (2/24), M. avium (1/24), M. szulgai (1/24) and M. fortuitum (1/24). The difference between NTM and TB case rates for the ⩾65-year-old age group significantly exceeded the difference for the reference group (patients aged 25–44 years) (OR (95% CI): 4.63 (1.03–20.90)). Pulmonary NTM diseases incidence positively correlated with prior TB history (OR (95% CI): 12.92 (3.24–31.82)). Moreover, pulmonary NTM patients were significantly more likely to exhibit underlying bronchiectasis than pulmonary TB patients (OR (95% CI): 18.89 (7.54–47.88)). In conclusion, approximately one-tenth of culture-positive suspected pulmonary TB patients are infected with NTM (most frequently M. intracellulare) in Zhejiang Province, China. The elderly and those with bronchiectasis or a history of TB are at the greatest risk of contracting pulmonary NTM disease.

scholarly journals Prevalence of cardiovascular risk factors among elderly Brazilians over eighty with ischemic stroke

2008 ◽  
Vol 66 (3a) ◽  
pp. 454-457 ◽  
Author(s):  
Alexandre Pieri ◽  
Mariana Spitz ◽  
Tania Oliveira Lopes ◽  
Claudia Garcia de Barros ◽  
Marcelo Wood Faulhaber ◽  
...  
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Ischemic Stroke ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Oldest Old ◽  
The Elderly ◽  
Catastrophic Event ◽  
Cardiovascular Involvement ◽  
Definition Of

INTRODUCTION: An ischemic stroke is usually a catastrophic event, mostly in the elderly. Cardiovascular involvement is the leading cause of ischemic stroke in this age population and hence the knowledge about its risk factors is important for the definition of specific policies of prevention. PURPOSE: To evaluate the prevalence of cardiovascular risk factors in patients with age equal to or above 80 in a hospital population with ischemic stroke. METHOD: Retrospective study of consecutive patients diagnosed with ischemic stroke admitted to a tertiary health facility. RESULTS: From September 2004 to March 2006, 215 patients were studied. There was a female preponderance (p<0.01). Among patients over eighty, 72% had hypertension and atrial fibrillation was more common among the oldest old (p<0.01). CONCLUSION: Hypertension and atrial fibrillation should be treated aggressively in the elderly. Anticoagulants should be considered more often in these patients.

scholarly journals Neurosarcoidosis Presenting With Recurrent Strokes

2016 ◽  
Vol 7 (2) ◽  
pp. 91-95 ◽  
Author(s):  
Naheed Raza ◽  
Karisa C. Schreck
Keyword(s):  
Risk Factors ◽  
Young People ◽  
Elderly Patients ◽  
Classification Scheme ◽  
The Elderly ◽  
Secondary Stroke Prevention ◽  
High Grade ◽  
Age Group ◽  
Vascular Risk ◽  
Recurrent Strokes

Neurosarcoidosis is a rare but important cause of stroke as it is treatable. Cases reported thus far have primarily been in young people who are relatively healthy. Here we report the case of a 73-year-old woman presenting with recurrent strokes and high-grade intracranial stenosis caused by probable neurosarcoidosis. This is unique as neurosarcoidosis is not usually considered as an etiology for recurrent strokes in our patient’s age-group. We review and categorize published cases of neurosarcoidosis causing stroke and describe a classification scheme for certainty of diagnosis. Given the implications of this diagnosis for secondary stroke prevention, we recommend that neurosarcoidosis be considered in the differential for patients with few vascular risk factors, recurrent strokes refractory to medical treatment, or possible vasculitis even in the elderly patients.

scholarly journals Pola Hidup Penderita Hipertensi di Desa Duata Karya Kecamatan Masama Tahun 2021

2021 ◽  
Vol 12 (2) ◽  
Author(s):  
Pipin Kumalasari ◽  
Marselina Sattu ◽  
Mirawati Tongko ◽  
Ramli Bidullah ◽  
Nurhendra Gunawan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Diastolic Pressure ◽  
Univariate Analysis ◽  
Coffee Consumption ◽  
Secondary Data ◽  
Primary Data ◽  
Age Group ◽  
Salt Consumption ◽  
Descriptive Research ◽  
Spiral Type

Hipertensi adalah peningkatan tekanan darah sistolik sedikitnya 140 mmHg dan tekanan diastolik sedikitnya 90 mmHg. Sesuai dengan data di wilayah kerja Puskesmas Tangeban Kecamatan Masama tahun 2020, bahwa Desa Duata Karya merupakan satu-satunya Desa yang penyakit hipertensi tertinggi. Penelitian ini bertujuan untuk mengetahui pola hidup penderita hipertensi di Desa Duata Karya Kecamatan Masama menggunakan jenis penelitian deskriptif, menggunakan total sampling. Pengumpulan data berdasarkan data primer dan data sekunder. Pengolahan data menggunakan program SPSS. Analisis dalam penelitian ini menggunakan analisis univariat dan di sajikan dalam bentuk tabel yang menggambarkan penyajian data dalam bentuk distribus frekuensi. Hasil penelitian menunjukkan bahwa faktor risiko tidak dapat di modivikasi yaitu jenis kelamin responden terbanyak pada jenis kelamin perempuan (59,8%), umur terbanyak adalah golongan umur 61 tahun keatas (58,5%), faktor risiko keturunan sebagian besar responden tidak memiliki keturunan (43,9%), dan untuk faktor risiko yang dapat di modivikasi mendapatkan hasil bahwa penggunaan kontrasepsi oral sebanyak  (6,5%) responden dan kontrasepsi terbanyak yang digunakan adalah kontrasepsi jenis spiral sebanyak  (54,3%), faktor risiko konsumsi garam lebih pada responden sebanyak 71 responden (86,6%), faktor risiko konsumsi kopi sebagian besar mengkonsumsi kopi (84,1%). Untuk itu di harapkan kepada masyarakat untuk tetap menjaga pola hidup dengan mengurangi konsumsi garam berlebihan, tidak mengkonsumsi alkohol, dan mengurangi konsumsi kopi Hypertension is an increase in systolic blood pressure of at least 140 mmHg and diastolic pressure of at least 90 mmHg. In accordance with the data in the working area of Tangeban Health Center masama subdistrict in 2020, that Duata Karya Village is the only village with the highest hypertension disease. This study aims to find out the lifestyle of people with hypertension in Duata Karya Village masama subdistrict using a type of descriptive research, using total sampling. Data collection based on primary data and secondary data. Data processing using the SPSS program. The analysis in this study uses univariate analysis and is presented in the form of a table that describes the presentation of data in the form of frequency distribution. The results showed that the risk factors that cannot be modivikasi are the sex of the respondents mostly in the female sex (59.8%), the most age is the age group 61 years and above (58.5%), the risk factors of heredity most of the respondents do not have offspring (43.9%), and for risk factors that can be modivikasi get the result that the use of oral contraceptives as much as (6.5%) respondents and the most contraceptives used are spiral type contraceptives se many (54.3%), risk factors for more salt consumption in respondents as many as 71 respondents (86.6%), risk factors for coffee consumption mostly consumed coffee (84.1%). For this reason, it is expected to keep the lifestyle by reducing excessive salt consumption, not consuming alcohol, and reducing coffee consumption

scholarly journals Role of Fungal Infections in Carcinogenesis and Cancer Development; A Literature Review

2021 ◽  
Author(s):  
Kamran Hosseini ◽  
Hossein Ahangari ◽  
Florence Chapeland-leclerc ◽  
Gwenael Ruprich-Robert ◽  
Vahideh Tarhriz ◽  
...  
Keyword(s):  
Risk Factors ◽  
Fungal Infections ◽  
The Elderly ◽  
Fungal Species ◽  
Clinical Findings ◽  
Cancer Development ◽  
Microbial Infection ◽  
Common Causes ◽  
Acquired Immunodeficiency ◽  
Comprehensive Framework

Cancer is a serious debilitating disease and one of the most common causes of death. In recent decades the high risk of various cancers enforced scientists to discover novel prevention and treatment methods to diminish the mortality of this terrifying disease. Accordingly, its prevention can be possible in near future. Based on epidemiological evidence, there is a clear link between pathogenic fungal infections and cancer development. This association is often seen in people with weakened immune systems such as the elderly and people with acquired immunodeficiency (AIDS). Carcinoma in these people is first seen chronically and then acutely. Although the different genetic and environmental risk factors are involved in carcinogenesis, one of the most important risk factors is fungal species and infections associating with cancers etiology. Now it is known that microbial infection is responsible for initiating 2.2 million new cancer cases. In this way, many recent studies have focused on investigating the role and mechanism of fungal infections in diverse cancers occurrence. This review provides a comprehensive framework of the latest clinical findings and the association of fungal infections with versatile cancers including esophageal, gastric, colorectal, lung, cervical, skin, and ovarian cancer.

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