scholarly journals Carcinoembryonic Antigen (CEA) dan Neutrofil-to-Limfosit Ratio (NLR) sebagai Faktor Prediktif Kanker Kolorektal

2019 ◽  
Vol 7 (1) ◽  
pp. 68-76
Author(s):  
Retno Martini Widhyasih ◽  
Suci Dwi Rahmadhanti ◽  
Rizana Fajrunni'mah
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Secondary Data ◽  
Cross Sectional ◽  
The Third ◽  
A Value ◽  
The World ◽  
Cross Sectional Design ◽  
Colorectal Cancer Patients ◽  
Predictive Indicator

Colorectal cancer is a cancer that attacks the colon to the rectum. This cancer is the fourth most cancer in the world, and the second most cancer in western countries, and the third most common cause of cancer that occurs in men and women in 2012 in Indonesia. 72.4% of colorectal cancer patients have increased preoperative CEA levels, and increased NLR has been reported as a valuable predictive indicator of various types of cancer, including colorectal cancer. This study aims to analyze the correlation between CEA examination and NLR in colorectal cancer using secondary data with cross-sectional design. The sample of this study was all colorectal cancer patients in Tarakan Hospital, Central Jakarta, who examined CEA and complete hematology in 2014 - 2018. Based on the results of the study, it could be concluded that there was a correlation between CEA with NLR in colorectal cancer with a value of p = 0.000 smaller than alpha = 0.05, and the value of r = 0.78, meaning a strong correlation between CEA and NLR in colorectal cancer, so if there is an increase in CEA, it is accompanied by an increase in NLR.

scholarly journals Relationship Between Staging and Carcinoembryonic Antigen Serum Levels In Colorectal Cancer Patients'

2020 ◽  
Vol 2 (3) ◽  
pp. 118-123
Author(s):  
Chandra Agusrly ◽  
Taufik Sungkar ◽  
Gontar Alamsyah Siregar
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patient ◽  
Carcinoembryonic Antigen ◽  
Cancer Patients ◽  
Colorectal Cancer Patient ◽  
Serum Levels ◽  
Cross Sectional ◽  
Diagnosis And Prognosis ◽  
Cross Sectional Design ◽  
Colorectal Cancer Patients

The staging can be used as one of the prognostic factors providing a clinical picture of the patient in the future in colorectal cancer patient. In addition, carcinoembryonic antigen (CEA) as tumor markers can determine the commonly used diagnosis and prognosis of colorectal cancer. Objective: The aims study was to investigate the relationship of the staging and carcinoembryonic antigen serum levels in colorectal cancer patients. Methods. This was an analytical study with a cross-sectional design. The sample used was colorectal cancer patients at H. Adam Malik General Hospital, Medan from January 2016 to December 2018. As many as 52 subject study who met the inclusion and exclusion criteria. The Kruskal-Wallis test was used to determine relationship between staging and CEA serum levels. Results: The median value of carcinoembryonic antigen levels in Stage I, II, III, and IV group was (2.74 ng/ml vs 6.16 ng/ml vs 2.52 ng/ml, vs 26.87 ng/ml; p=0.003) respectively. Conclusion: There was relationship between staging and carcinoembryonic antigen serum levels in colorectal cancer patient

The impact of an ostomy on older colorectal cancer patients: a cross-sectional survey

2016 ◽  
Vol 32 (1) ◽  
pp. 89-94 ◽  
Author(s):  
N. M. Verweij ◽  
M. E. Hamaker ◽  
D. D. E. Zimmerman ◽  
Y. T. van Loon ◽  
F. van den Bos ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Colorectal Cancer Patients ◽  
The Impact

scholarly journals HUMAN DNA QUANTIFICATION IN THE STOOLS OF PATIENTS WITH COLORECTAL CANCER

2015 ◽  
Vol 52 (4) ◽  
pp. 293-298 ◽  
Author(s):  
Yolanda TEIXEIRA ◽  
Jacqueline Miranda LIMA ◽  
Maria Luiza Almeida Prado Oliveira SOUZA ◽  
Pedro AGUIAR Jr ◽  
Tiago Donizetti SILVA ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Cells ◽  
Cancer Patients ◽  
Roc Curve ◽  
Dna Quantification ◽  
Non Invasive ◽  
Human Dna ◽  
The World ◽  
Invasive Method ◽  
Colorectal Cancer Patients

Background - Colorectal cancer is one of the main cause of cancer in the world. Colonoscopy is the best screen method, however the compliance is less than 50%. Quantification of human DNA (hDNA) in the feces may be a possible screen non-invasive method that is a consequence of the high proliferation and exfoliation of cancer cells. Objective - To quantify the human DNA in the stools of patients with colorectal cancer or polyps. Methods - Fifty patients with CRC, 26 polyps and 53 with normal colonoscopy were included. Total and human DNA were analyzed from the frozen stools. Results - An increased concentration of hDNA in the stools was observed in colorectal cancer patients compared to controls and polyps. Tumors localized in the left side of the colon had higher concentrations of hDNA. There were no difference between polyps and controls. A cut off of 0.87 ng/mL of human DNA was determined for colorectal cancer patients by the ROC curve, with a sensitivity of 66% and a specificity of 86.8%. For polyps the cut off was 0.41, the sensitivity was 41% and the specificity 77.4%. Conclusion - A higher concentration of hDNA had been found in colorectal cancer patients The quantification of hDNA from the stools can be a trial method for the diagnosis of colorectal cancer.

scholarly journals QUALITY OF LIFE AMONG COLORECTAL CANCER PATIENTS AT THAI NGUYEN ONCOLOGY CENTER

2021 ◽  
Vol 62 (4) ◽  
Author(s):  
Nguyen To Quynh Chau ◽  
Nguyen Manh Tuan ◽  
Nguyen Thanh Nhai ◽  
Nguyen Thi Ngan ◽  
Tran Bao Ngoc
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Cross Sectional Study ◽  
Functional Score ◽  
Cross Sectional ◽  
European Organization ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Aim: To describe quality life’s colorectal cancer patients who are being treated at Thai Nguyenoncology center from June 2020 to August 2020.Objects and method: The descriptive cross- sectional study was conducted over 68 patientsdiagnosed with colorectal cancer by face to face interview using the European Organization forResearch and Treatment of Cancer (EORTC) QLQ-C30 and the EORTC QLQ-CR29.Results: Mean of overall health score was 51,96±18,78; mean of functional score was 21,49±12,42(1,71–47,06). In functional sector, social function was scored lowest. In symptomatic scale, appetiteloss was scored highest (47,06).Conclusion: Quality of life of colorectal cancer patients was medium level. Highest scores wereobserved for appetite loss and fatigue. To improve quality life’s patients, medical staffs need to keepenhancing symptoms and function for patients during treatment.

Attachment style, social support and finding meaning among spouses of colorectal cancer patients: Gender differences

2013 ◽  
Vol 13 (3) ◽  
pp. 527-535 ◽  
Author(s):  
Ilanit Hasson-Ohayon ◽  
Gil Goldzweig ◽  
Tal Sela-Oren ◽  
Noam Pizem ◽  
Gil Bar-Sela ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Social Support ◽  
Gender Differences ◽  
Cancer Patients ◽  
Attachment Style ◽  
Attachment Styles ◽  
Spousal Caregivers ◽  
Cross Sectional ◽  
Finding Meaning ◽  
Colorectal Cancer Patients

AbstractObjectives:The current study explores the relationship between attachment styles, social support, gender and finding meaning in caregiving among spousal caregivers of colorectal cancer patients.Methods:Sixty caregivers (30 men and 30 women) were administered questionnaires assessing attachment styles, social support and finding meaning in caregiving, using a cross-sectional design.Results:For male caregivers avoidance attachment is associated with their finding meaning, whereas for female caregivers social support is associated with their finding meaning.Significance of results:Psychological interventions for caregivers should take into consideration gender differences and might benefit from addressing the process of finding meaning in caregiving.

scholarly journals CLINICAL EVALUATION AND PATTERN OF SYMPTOMS IN COLORECTAL CANCER PATIENTS

2020 ◽  
Vol 57 (2) ◽  
pp. 131-136
Author(s):  
Marianne Regina Silva Potengy de MELLO ◽  
Silmara Fernandes MOURA ◽  
Camila Drumond MUZI ◽  
Raphael Mendonça GUIMARÃES
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Clinical Management ◽  
Gastrointestinal Symptoms ◽  
Signs And Symptoms ◽  
Tumor Stage ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Epidemiological Profile ◽  
Colorectal Cancer Patients

ABSTRACT BACKGROUND: Colorectal cancer is the third most common type of cancer in the world and the increased survival of the colorectal cancer population is very significant. Thus, it becomes relevant to study the symptoms associated with the progression of the disease and treatment, for proper clinical management. OBJECTIVE: To describe the clinical and epidemiological profile of colorectal cancer patients and to identify the most prevalent signs and symptoms patterns. METHODS: Cross-sectional study evaluating the prevalence of symptoms in 348 colorectal cancer patients admitted to a referral oncology hospital. We applied MSAS-BR scale and, through factor analysis with principal componente analysys, we performed the grouping of symptoms. RESULTS: There was a predominance of men, aged 60 years or older, married, white, with high school, moderately differentiated tumor, stage III/IV disease, colon cancer and no distant metastasis. The most prevalent symptoms were weight loss (67.53%) and the least prevalent were mouth sores (2.01%). The groupings of symptoms established were “fatigue and psychic symptoms”, “gastrointestinal symptoms”, “self-perceptive symptoms” and “general symptoms”, which described 80% of the symptoms presented. CONCLUSION: We evidenced the importance of identifying these symptoms clusters in order to improve strategies for clinical management in patients with colorectal cancer.

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