scholarly journals Sistematik Review: Faktor Resiko Obesitas terhadap Diabetes Mellitus Tipe 2 pada Remaja

2021 ◽  
Vol 7 (1) ◽  
pp. 233-242
Author(s):  
Barto Mansyah

Degenerative diseases or non-communicable diseases are caused by changes in lifestyle, especially changes in diet. One of the degenerative diseases is type 2 diabetes mellitus, characterized by insufficient insulin secretion, insulin resistance, and increased glucose production in the liver. Adolescence is a critical period, unhealthy dietary habits are one of the risky behaviors in adolescence, and an unhealthy diet in adolescents is one of the causes of obesity. Obesity is a hallmark of type 2 diabetes mellitus, and most adolescents with type 2 diabetes mellitus are obese at diagnosis. This study is a systematic review study with article search methodology through Google Scholar, PubMed, and Elsevier with the keywords Obesity as a Risk Factor for Type II Diabetes Mellitus in adolescents. There are 12 research articles identified. It is known that obsession in adolescents is a risk factor for diabetes mellitus—type 2 diabetes mellitus in adulthood. The importance of providing education that focuses on lifestyle changes that aim to reduce the level of overweight and obesity in children and adolescents as well as education is also given to all family members so that families understand the importance of lifestyle changes for the successful management of type 2 diabetes mellitus.

2015 ◽  
Vol 7 (1) ◽  
pp. 1-6
Author(s):  
Kyuzi Kamoi

Previous longitudinal studies have demonstrated that blood pressure measurements at home (HBP) in the wakening- up display stronger predictive power for death, and vascular complications in patients with type 2 diabetes mellitus (T2DM) than clinic blood pressure measurements (CBP). The leading cause of death was cancer. Patients with T2DM have associated with cancer, and high CBP is a risk factor for cancer. Therefore, this study investigated whether HBP or CBP is related to cancer event in patients with T2DM for 10 years. At baseline, 400 Japanese patients with T2DM were classified as hypertensive (HT) or normotensive (NT) based on HBP and CBP. Mean (± SD) duration was 95 ± 35 months. Primary and secondary endpoints were death and cancer, respectively. Differences in outcome between HT and NT were analyzed using survival curves from Kaplan-Meier analysis and log-rank testing. Associated risk factors were assessed using Cox proportional hazards. On basis of HBP, death and event of cancer were significantly higher in HT than in NT. The leading cause of death was cancer. On basis of CBP, there was no significant difference in the incidence of death and event of cancer between patients with HT and NT at baseline. Associated risk factor for cancer was T2DM. Home morning HT may be reflected more keenly state of cancer than clinic HT, which may be superior to clinic NT. When we meet with such patients, it is important that cancer may be one of many causes for morning HT in Japanese patients with T2DM.


2020 ◽  
Vol 42 (3) ◽  
pp. 92-96
Author(s):  
Ishwor Sharma ◽  
Sanjay K Gupta ◽  
Kiran Niraula

Introduction Overweight and obesity with their surrogate anthropometric markers like body mass index (BMI), waist circumference (WC) and waist hip ratio (WHR) have been shown to be strongly associated with Type 2 diabetes mellitus. Neck circumference (NC) though less used can be an equally effective alternative to diagnose overweight and obesity in patients with Type 2 diabetes mellitus in a resource limited setting. MethodsPatients who had Type 2 Diabetes Mellitus for 5 years or more and above 35 years underwent simple random sampling. Weight, height, WC and NC were measured. BMI was calculated and patients were graded into overweight and obesity based on the Asian cutoffs for BMI and abdominal obesity. ResultsAmong 100 patients enrolled in this study, 45% were men and the mean age was 53.05. Mean neck circumference was 36.55 ± 1.28 cm and 35.27 ± 1.78 cm for male and female respectively. NC was positively correlated with WC and BMI in both men and women (p ˂ 0.001). In the ROC curves, NC presented the largest area under the curve (AUC) for overweight in males (p ˂ 0.001), while NC presented a large AUC for central obesity in both genders. Furthermore, the cut off value of neck circumference for overweight was 35.6 cm in males vs 35.2 cm in females and for central obesity was 36.75 cm in males vs 34.75 cm in females. ConclusionNeck circumference was positively associated with overweight and central obesity in patients with type 2 diabetes mellitus.


2021 ◽  
Vol 11 (2) ◽  
pp. 339-343
Author(s):  
Ling Hu ◽  
Xiao-Ling Yin ◽  
Ting Li

Objective: This study aims to analyze the blood cadmium level and prevalence of type 2 diabetes mellitus in the general population and explore the correlation between blood cadmium levels and the prevalence of type 2 diabetes mellitus. Methods: From February to December 2017, a multistage, random cluster sampling method was adopted to conduct this cross-sectional epidemiological survey of permanent residents aged >18 years in Nanchang, Jiangxi province (including one urban area, Changdong district and one county, Jinxing county). Blood cadmium levels and the prevalence of type 2 diabetes in the population were analyzed, and the correlation between blood cadmium levels and the incidence of type 2 diabetes was analyzed. Results: The average blood cadmium content of the population in Nanchang (Changdong town, Jinxian county) was 2.91 ± 0.08 ug/L, and the prevalence of type 2 diabetes was 9.2%. The average blood cadmium content of the population in Jinxian county was higher than that of the population of the Changdong district. The results of multivariate regression analysis indicate that high blood cadmium levels are a risk factor for type 2 diabetes. Conclusions: Elevated levels of cadmium in human blood may be a risk factor for type 2 diabetes.


Gerontology ◽  
2019 ◽  
Vol 66 (2) ◽  
pp. 209-210
Author(s):  
Pouneh K. Fazeli ◽  
Hang Lee ◽  
Matthew L. Steinhauser

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