scholarly journals The Biophysical Modeling of the Nephrogenesis in the Perinatal Periods

2020 ◽  
Vol 5 (3) ◽  

Our experiments analyzed the microscopic picture of kidneys of patients who died during gestational age or infancy. We wanted to investigate nephrogenesis in its ontogenetic development. We only conducted the analysis until the age of three, because the one million nephron number characteristic of the kidney in adulthood is already developed by the age of three. This perinatal time interval was divided into five periods. Intrauterine are the early fetal (3–5 months) and late fetal periods, neonates (0–1 months), infants (1–12 months) and young children (1–3 years). The specific case numbers are not taken into account, only general remarks are communicated. We found that the structural and functional unit of the kidney is the nephron, which undergoes three initial stages: pro-, meso- and metanephros. There are two periods of accumulation: late fetal and infant age. After birth, the number of incomplete renal corpuscles is negligible. Nephrogenesis occurs from the outside to the inside. By the age of three, the volume of the cortex doubles that of the marrow. In further periods of ontogenesis, the nephron count remains unchanged, only the volume of the nephrons increases. When modelling kidney function, we found that the body is “resting” some of the nephrons, because it is during this time that the cell walls resulting from cavitation are regenerated.

Author(s):  
Janos Vincze ◽  
Gabriella Vincze Tiszay

We wanted to investigate nephrogenesis in its ontogenetic development (in the perinatal periods). This perinatal time interval was divided into five periods. Intrauterine are the early fetal (3–5 months) and late fetal periods, neonates (0–1 months), infants (1–12 months) and young children (1–3 years). We only conducted the analysis until the age of three, because the one million nephron number characteristic of the kidney in adulthood is already developed by the age of three. We found that the structural and functional unit of the kidney is the nephron, which undergoes three initial stages: pro-, meso- and metanephros. There are two periods of accumulation: late fetal and infant age. After birth, the number of incomplete renal corpuscles is negligible. In further periods of ontogenesis, the nephron count remains unchanged, only the volume of the nephrons increases. When modeling kidney function, we found that the body is “resting” some of the nephrons, because it is during this time that the cell walls resulting from cavitation are regenerated


2020 ◽  
Vol 5 (3) ◽  

The kidney excretes excess substances through urine: decomposition products of substances foreign to the metabolism and organism (medicines, nutritional supplements). The kidneys also play an important regulatory role (fluid and water balance, pH, blood pressure, hematopoiesis, bone metabolism). Our experiments analyzed the microscopic picture of kidneys of patients who died during gestational age or infancy. We found that the structural and functional unit of the kidney is the nephron. The nephrons have two important mechanisms: filtration and reabsorb. We determined the spatial form of the nephrons is rotating ellipsoid. In our opinion, the excretory apparatus should have a control associated with its own structure, which is likely to consist of neurons with hyperordonated spatial structure, called the “hypothetical secondary brain”.


2017 ◽  
Vol 5 (3) ◽  
pp. 272
Author(s):  
Jordi Morell Rovira

The article explores the relationship of the person with the hole through both literal and metaphorical situations. On the one hand, it points up the body in seclusion and suspended in a time interval, as in the case of the accident at the mine in San José (Chile) or works by artists like J. Wall, G. Schneider or R. Ondák. In this way, opposed feelings evoke the experiences of waiting and/or punishment, which are explanatory of a confined body or a hole. Literature, cinema and art deal with these events from multiple aspects, which become existential allegories about the individual. On the other hand, the act of digging gains prominence as a symbol of work, but also of the absurd. Recalling the ambivalence that may suggest a person making a hole, this article carries out a drift through works by artists of different generations and contexts, such as C. Burden, M. Heizer, F. Miralles, Geliti, S. Sierra, F. Alÿs, M. Salum, X. Ristol or N. Güell. A series of clearly performative or conceptual works, where the act of digging, drilling, burying or unburying become common practices that show the diversity of meanings and intentions.


2017 ◽  
Vol 3 (1) ◽  
pp. 76
Author(s):  
Siti Asiyah ◽  
Dwi Estuning Rahayu ◽  
Wiranti Dwi Novita Isnaeni

The needed of Iron Tablet in pregnancy was increase than mother who not pregnant.  That  cause of  high metabolism at the pregnancy for formed of  fetal organ and energy. One of effort for prevent anemia in mother pregnant with giving the Iron tablet and vitamin c. The reason of  this research in 4 June – 11 July 2014 is for compare the effect of  iron tablet suplementation with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks In Desa Keniten Kecamatan Mojo Kabupaten Kediri. This research method using comparative analytical.  Research design type of Quasy Eksperiment that have treatment group and control group. Treatment group will giving by Iron tablet and 100 mg vitamin C, and control group just giving by iron tablet during 21 days. Population in this research are all of mother pregnant with Gestational Age Of 16-32 Weeks with Sampling technique is  cluster random sampling is 29 mother pregnant. Comparison analysis of  iron tablet suplementation effect with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks, data analysis using Mann Whitney U-test and the calculated U value (44,5) less than U-table (51). So there was difference of iron tablet suplementation effect with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks Therefore, the addition of vitamin C on iron intake is needed to increase the uptake of iron tablets. When the amount of iron uptake increases, the reserves of iron in the body will also increase, so as to prevent anemia in pregnant women; Keywords : Iron Tablet (Fe), Vitamin C, Hemoglobin level, Mother Pregnant


2018 ◽  
Vol 13 (3) ◽  
pp. 364-381
Author(s):  
Margot Gayle Backus ◽  
Spurgeon Thompson

As virtually all Europe's major socialist parties re-aligned with their own national governments with the outbreak of World War I, Irish socialist and trade unionist James Connolly found himself internationally isolated by his vociferous opposition to the war. Within Ireland, however, Connolly's energetic and relentless calls to interrupt the imperial transportation and communications networks on which the ‘carnival of murder’ in Europe relied had the converse effect, drawing him into alignment with certain strains of Irish nationalism. Connolly and other socialist republican stalwarts like Helena Molony and Michael Mallin made common cause with advanced Irish nationalism, the one other constituency unamenable to fighting for England under any circumstances. This centripetal gathering together of two minority constituencies – both intrinsically opposed, if not to the war itself, certainly to Irish Party leader John Redmond's offering up of the Irish Volunteers as British cannon fodder – accounts for the “remarkably diverse” social and ideological character of the small executive body responsible for the planning of the Easter Rising: the Irish Republican Brotherhood's military council. In effect, the ideological composition of the body that planned the Easter Rising was shaped by the war's systematic diversion of all individuals and ideologies that could be co-opted by British imperialism through any possible argument or material inducement. Although the majority of those who participated in the Rising did not share Connolly's anti-war, pro-socialist agenda, the Easter 1916 Uprising can nonetheless be understood as, among other things, a near letter-perfect instantiation of Connolly's most steadfast principle: that it was the responsibility of every European socialist to throw onto the gears of the imperialist war machine every wrench on which they could lay their hands.


Author(s):  
Mohammed Ibrahim ◽  
Alaa Zaky ◽  
Mohsen Afouna ◽  
Ahmed Samy

Carrier erythrocytes are emerging as one of the most promising biological drug delivery systems investigated in recent decades. Beside its biocompatibility, biodegradability and ability to circulate throughout the body, it has the ability to perform extended release system of the drug for a long period. The ultimate goal of this study is to introduce a new carrier system for Salbutamol, maintaining suitable blood levels for a long time, as atrial to resolve the problems of nocturnal asthma medication Therefore in this work we study the effect of time, temperature as well as concentration on the loading of salbutamol in human erythrocytes to be used as systemic sustained release delivery system for this drug. After the loading process is performed the carrier erythrocytes were physically and cellulary characterized. Also, the in vitro release of salbutamol from carrier erythrocytes was studied over time interval. From the results it was found that, human erythrocytes have been successfully loaded with salbutamol using endocytosis method either at 25 Co or at 37 Co . The highest loaded amount was 3.5 mg/ml and 6.5 mg/ml respectively. Moreover, the percent of cells recovery is 90.7± 1.64%. Hematological parameters and osmotic fragility behavior of salbutamol loaded erythrocytes were similar that of native erythrocytes. Scanning electron microscopy demonstrated that the salbutamol loaded cells has moderate change in the morphology. Salbutamol releasing from carrier cell was 43% after 36 hours in phosphate buffer saline. The releasing pattern of the drug from loaded erythrocytes showed initial burst release in the first hour followed by a very slow release, obeying zero order kinetics. It concluded that salbutamol is successfully entrapped into erythrocytes with acceptable loading parameters and moderate morphological changes, this suggesting that erythrocytes can be used as prolonged release carrier for salbutamol.


Author(s):  
Lisa Sousa

The Woman Who Turned Into a Jaguar examines gender relations in indigenous societies of central Mexico and Oaxaca from the 1520s to the 1750s, focusing mainly on the Nahua, Ñudzahui (Mixtec), Bènizàa (Zapotec), and Ayuk (Mixe) people. This study draws on an unusually rich and diverse corpus of original sources, including Ñudzahui- (Mixtec-), Tíchazàa- (Zapotec-), and mainly Nahuatl-language and Spanish civil and criminal records, published texts, and pictorial manuscripts. The sources come from more than 100 indigenous communities of highland Mexico. The book considers women’s lives in the broadest context possible by addressing a number of interrelated topics, including: the construction of gender; concepts of the body; women’s labor; marriage rituals and marital relations; sexual attitudes; family structure; the relationship between household and community; and women’s participation in riots and other acts of civil disobedience. The study highlights subtle transformations and overwhelming continuities in indigenous social attitudes and relationships. The book argues that profound changes following the Spanish conquest, such as catastrophic depopulation, economic pressures, and the imposition of Christian marriage, slowly eroded indigenous women’s status. Nevertheless, gender relations remained inherently complementary. The study shows how native women and men under colonial rule, on the one hand, pragmatically accepted, adopted, and adapted certain Spanish institutions, concepts, and practices, and, on the other, forcefully rejected other aspects of colonial impositions. Women asserted their influence and, in doing so, they managed to retain an important position within their households and communities across the first two centuries of colonial rule.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Caleb Liang ◽  
Wen-Hsiang Lin ◽  
Tai-Yuan Chang ◽  
Chi-Hong Chen ◽  
Chen-Wei Wu ◽  
...  

AbstractBody ownership concerns what it is like to feel a body part or a full body as mine, and has become a prominent area of study. We propose that there is a closely related type of bodily self-consciousness largely neglected by researchers—experiential ownership. It refers to the sense that I am the one who is having a conscious experience. Are body ownership and experiential ownership actually the same phenomenon or are they genuinely different? In our experiments, the participant watched a rubber hand or someone else’s body from the first-person perspective and was touched either synchronously or asynchronously. The main findings: (1) The sense of body ownership was hindered in the asynchronous conditions of both the body-part and the full-body experiments. However, a strong sense of experiential ownership was observed in those conditions. (2) We found the opposite when the participants’ responses were measured after tactile stimulations had ceased for 5 s. In the synchronous conditions of another set of body-part and full-body experiments, only experiential ownership was blocked but not body ownership. These results demonstrate for the first time the double dissociation between body ownership and experiential ownership. Experiential ownership is indeed a distinct type of bodily self-consciousness.


2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Jung-ah Choi ◽  
Jae Hoon Lim

AbstractThis paper is a self-reflective narrative of our teaching experience as two immigrant Asian female professors who teach Multicultural Education. Employing collaborative autoethnography (CAE), the study addresses the issues of authority, positionality, and legitimacy of knowledge claims in critical feminist pedagogy. Two research questions guided our inquiry: 1. How does a teacher’s racial positionality play out in exercising professional knowledge, and conversely, 2. How does seemingly neutral professional knowledge become racialized in the discussions of race? Major findings demonstrate the double-edged contradictions in the body/knowledge nexus manifested in our everyday teaching contexts. On the one hand, the bodily dimension of teacher knowledge is de-racialized because of institutional norms and cultures. On the other hand, there are times professional knowledge becomes racialized through the teacher’s body. Understanding the body/knowledge nexus that invites precarious power dynamics in racial discussions and even blatantly dismisses our professional knowledge, we, as an immigrant faculty of color, find it impossible to create a safe environment for participatory, critical discourse. Acknowledging our triple marginality, we put forth the concept of “pedagogy of fear” (Leonardo, Z., & Porter, R. K. (2010). Pedagogy of fear: Toward a Fanonian theory of ‘safety’ in race dialogue. Race, Ethnicity and Education, 13(2), 139–157) which squarely disrupts the idea of a safe environment in race dialog and urges teachers to confront their own/their students’ fear and create a space of teaching vulnerably.


Tempo ◽  
2021 ◽  
Vol 75 (296) ◽  
pp. 7-20
Author(s):  
Bethany Younge

AbstractThis article adopts a disability studies perspective to evaluate the ways in which Mauricio Kagel's Repertoire from Staatstheater reimagines human bodies. Objects and bodies interact in myriad ways within the one hundred vignettes of Repertoire: some objects hinder or aid the bodies on stage, while others become incorporated within the body, acting as a single expressive unit. My analysis demonstrates the ways in which both objects and bodies transform their traditional roles as ascribed by society, rejecting procrustean physiques. Using disability studies concepts such as embodiment and experientialism I evaluate sound and physical action as inextricable expressions of imaginative corporealities. Reflecting upon Kagel's identity as an outsider of the European avant-garde, as well as his irreverence for oppressive social institutions, I evince that other forms of hierarchical disruptions are at play, namely that abled bodies do not preside over disabled ones and notions of beauty hold no clout.


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