scholarly journals Transplacentally transmitted organophosphorous compound poisoning in a newborn : Acase report and narrative review of literature

2020 ◽  
Vol 8 (2) ◽  
pp. 120-123
Author(s):  
Nargis Ara Begum ◽  
Mohammad Omar Faruq ◽  
Shahnaz Parvin Siddiqua ◽  
Runa Laila ◽  
Suman Sharker ◽  
...  
Keyword(s):  
Neonatal Intensive Care ◽  
Early Recognition ◽  
Perinatal Asphyxia ◽  
Medical Emergency ◽  
Rare Occurrence ◽  
Review Of Literature ◽  
Organophosphorous Compound ◽  
History Of ◽  
The Tropics ◽  
Treatable Condition

Organophosphorous compound (OPC) poisoning in the newborn is a medical emergency but completely treatable condition. Early recognition and treatment is of paramount importance in preventing fatality. A newbornmale of severe perinatal asphyxia was admitted in our neonatal intensive care unit (NICU) with a history of maternal OPC poisoning 31 hours before delivery. We treated the case on urgent basis, had stormy neonatal course and finally baby went home safely. OPC poisoning in newborn is a rare occurrence in the tropics. We report a rare case of transplacentally transmission of OPC poisoning innewborn and it is going to be 3rd and latest such reported case across the world upon literature search. Bangladesh Crit Care J September 2020; 8(2): 120-123

scholarly journals Subacute Thyroiditis from COVID-19 Infection: A Case Report and Review of Literature

2020 ◽  
pp. 1-5
Author(s):  
Akshay Khatri ◽  
Esti Charlap ◽  
Angela Kim
Keyword(s):  
Clinical Features ◽  
Clinical Laboratory ◽  
Early Recognition ◽  
Subacute Thyroiditis ◽  
The Novel ◽  
Review Of Literature ◽  
Successful Management ◽  
Case Presentation ◽  
Radiologic Findings ◽  
History Of

<b><i>Introduction:</i></b> The novel severe-acute-respiratory-syndrome-coronavirus-2 (SARS-CoV-2) virus has led to the ongoing Coronavirus disease 2019 (COVID-19) disease pandemic. There are increasing reports of extrapulmonary clinical features of COVID-19, either as initial presentations or sequelae of disease. We report a patient diagnosed with subacute thyroiditis precipitated by COVID-19 infection, as well as review the literature of similar cases. <b><i>Case Presentation:</i></b> A 41-year-old female with no significant personal or family history of endocrinologic disorders presented with clinical features of thyroiditis that began after COVID-19 infection. Clinical, laboratory, and radiologic findings were indicative of subacute thyroiditis. Workup for potential triggers other than SARS-CoV-2 was negative. <b><i>Discussion/Conclusion:</i></b> We compared the clinical and diagnostic findings of our patient with other well-documented cases of subacute thyroiditis presumed to be triggered by SARS-CoV-2 viral infection. We also reviewed the literature related to the potential mechanisms leading to thyroiditis. Clinicians must be aware of the possibility of thyroid dysfunction after COVID-19 infection. Early recognition and timely anti-inflammatory therapy help in successful management.

scholarly journals Unusual case of Marchiafava-Bignami disease presenting as axial hypotonia

2019 ◽  
Vol 76 (6) ◽  
pp. 645-647
Author(s):  
Svetlana Miletic-Drakulic ◽  
Jasna Jevdjic ◽  
Dejan Aleksic ◽  
Gordana Toncev
Keyword(s):  
Alcohol Consumption ◽  
Corpus Callosum ◽  
Motor Coordination ◽  
Early Recognition ◽  
Medical Emergency ◽  
First Case ◽  
Heavy Alcohol Consumption ◽  
History Of ◽  
Acute Form ◽  
The Brain

Introduction. Marchiafava-Bignami disease is a rare disorder mostly associated with chronic heavy alcohol consumption that results in progressive demyelination and necrosis of the corpus callosum. Case report. We reported a 35-year-old woman with a history of alcohol consumption and malnutrition. Neurological examination revealed axial hypotonia, dysarthric speech and lack of motor coordination. The brain multislice computed tomography imaging demonstrated hypodense lesion of the corpus callosum. On the basis of her history, clinical features and imaging studies, the diagnosis of an acute form of Marchiava-Bignami disease was made. Definite diagnosis was confirmed at autopsy. Conclusion. Marchiafava-Bignami disease is of a medical emergency and early recognition and early aggressive treatment are critical for a good clinical outcome. To our knowledge, this is the first case of Marchiafava-Bignami disease presented with axial hypotonia.

scholarly journals Severe Birth Asphyxia without Sequelae: A Case Report

2019 ◽  
Vol 57 (218) ◽  
Author(s):  
Sujata Dahal ◽  
Roshan Lama ◽  
Nita Lohala ◽  
Prashant Simkhada ◽  
Meena Thapa ◽  
...  
Keyword(s):  
Heart Rate ◽  
Neonatal Intensive Care ◽  
Life Support ◽  
Perinatal Asphyxia ◽  
Neonatal Resuscitation ◽  
Birth Asphyxia ◽  
Advanced Life Support ◽  
Neonatal Morbidity ◽  
Neurodevelopmental Delay ◽  
History Of

Perinatal asphyxia is one of the major causes of neonatal morbidity and mortality. It mainly causes neurodevelopmental delay leading to hypoxic-ischemic encephalopathy. We present here the case of a preterm male baby of 1670 grams born at 31+3 weeks of gestation delivered by 25-year-old primi mother through vaginal delivery with history of umbilical cord prolapse. At birth, the baby had no heart rate and cyanosed following which he was resuscitated according to the Neonatal Advanced Life Support 2015 guidelines protocol.  After 5 minutes of neonatal resuscitation, the baby’s heart rate reappeared, but was only upto 20 beats/min and resuscitation thus continued. But heart rate did not improve despite of using all form of resuscitation procedure including intubation and drugs. After 2 hours, baby cried spontaneously and later baby was managed in Neonatal Intensive Care Unit according to the neonatal unit protocol of the hospital.   

scholarly journals FULL TERM BABIES;

2017 ◽  
Vol 24 (06) ◽  
pp. 828-833
Author(s):  
Abdur Rehman Malik ◽  
Ahmed Iqbal Quddusi ◽  
Nazia Fatima ◽  
Imran Iqbal ◽  
Azhar Mehmood Javeed
Keyword(s):  
Birth Weight ◽  
Neonatal Intensive Care ◽  
Perinatal Asphyxia ◽  
Full Term ◽  
P Value ◽  
Cranial Ultrasound ◽  
Positive Correlation ◽  
Cranial Sonography ◽  
History Of ◽  
Moderate Positive Correlation

Introduction: Perinatal asphyxia is one of the most common causes of neonatalmorbidity and mortality in most countries of the world. The objective of my study was to assessthe correlation of clinical findings of perinatal asphyxia with cranial sonography in full termbabies. Study Design: Retrospective study. Setting: Neonatal Intensive Care Unit of Children’sHospital Multan. Period: January 2016 to October 2016. Material and Methods: 100 fullterm babies having history of delayed cry were scanned within three days of birth in NeonatalIntensive Care Unit of Children’s Hospital Multan. Clinically findings including full term babies,birth weight, grunting, cyanosis history of mode delivery, resuscitation history, delayed cry andhypoxic ischemic encephalopathy (HIE) grades were taken from baby’s hospital file record andstandard images including coronal and sagittal plans were taken by Ultrasound machine probeof frequency 3-5 MHz. Findings were recorded on data collection sheets and spread on EXELsheets. Correlation was found by using SPSS software. Result: Out of 100 neonates 63 weremale and 37 were female with birth weight (2.4-3.6) having mean ± SD 3.08 ± 0.53. HIE grades(mild, moderate and severe) were found in 12, 83, 5 babies respectively and ultrasound grades0 (normal/ mild echogenic), grade 1 (moderate echogenic) and grade 2 (severe/generalizedechogenic) were found in 32, 52, 16 neonates respectively with r= 0.37 and P-value < 0.05showing moderate positive correlation. Conclusion: Cranial ultrasound is a good screeningtool to evaluate asphyxiated neonatal brain. It has a moderate positive correlation with clinicalfindings.

In situ deteriorating patient simulation in general practice

2020 ◽  
Vol 70 (suppl 1) ◽  
pp. bjgp20X711425
Author(s):  
Joanna Lawrence ◽  
Petronelle Eastwick-Field ◽  
Anne Maloney ◽  
Helen Higham
Keyword(s):  
Life Support ◽  
Early Recognition ◽  
Phase 1 ◽  
Patient Simulation ◽  
Medical Emergency ◽  
Phase 2 ◽  
Action Plans ◽  
Integrated Simulation ◽  
Deteriorating Patient

BackgroundGP practices have limited access to medical emergency training and basic life support is often taught out of context as a skills-based event.AimTo develop and evaluate a whole team integrated simulation-based education, to enhance learning, change behaviours and provide safer care.MethodPhase 1: 10 practices piloted a 3-hour programme delivering 40 minutes BLS and AED skills and 2-hour deteriorating patient simulation. Three scenarios where developed: adult chest pain, child anaphylaxis and baby bronchiolitis. An adult simulation patient and relative were used and a child and baby manikin. Two facilitators trained in coaching and debriefing used the 3D debriefing model. Phase 2: 12 new practices undertook identical training derived from Phase 1, with pre- and post-course questionnaires. Teams were scored on: team working, communication, early recognition and systematic approach. The team developed action plans derived from their learning to inform future response. Ten of the 12 practices from Phase 2 received an emergency drill within 6 months of the original session. Three to four members of the whole team integrated training, attended the drill, but were unaware of the nature of the scenario before. Scoring was repeated and action plans were revisited to determine behaviour changes.ResultsEvery emergency drill demonstrated improved scoring in skills and behaviour.ConclusionA combination of: in situ GP simulation, appropriately qualified facilitators in simulation and debriefing, and action plans developed by the whole team suggests safer care for patients experiencing a medical emergency.

Internal herniation during pregnancy after banded Roux-en-Y gastric bypass: a unique location

2020 ◽  
Vol 13 (12) ◽  
pp. e236798
Author(s):  
Daniëlle Susan Bonouvrie ◽  
Evert-Jan Boerma ◽  
Francois M H van Dielen ◽  
Wouter K G Leclercq
Keyword(s):  
Gastric Bypass ◽  
Small Bowel ◽  
Neonatal Intensive Care ◽  
Postoperative Recovery ◽  
Internal Herniation ◽  
Referral Centre ◽  
Mri Scan ◽  
Tertiary Referral Centre ◽  
Bariatric Complications ◽  
History Of

A 26-year-old multigravida, 30+3 weeks pregnant woman, was referred to our tertiary referral centre with acute abdominal pain and vomiting suspected for internal herniation. She had a history of a primary banded Roux-en-Y gastric bypass (B-RYGB). The MRI scan showed a clustered small bowel package with possible mesenteric swirl diagnosed as internal herniation. A diagnostic laparoscopy was converted to laparotomy showing an internal herniation of the alimentary limb through the silicone ring. The internal herniation was reduced by cutting the silicone ring. Postoperative recovery, remaining pregnancy and labour were uneventful. During pregnancy after B-RYGB, small bowel obstruction can in rare cases occur due to internal herniation through the silicone ring. Education regarding this complication should be provided before bariatric surgery. Treatment of women, 24 to 32 weeks pregnant, in a specialised centre for bariatric complications with a neonatal intensive care unit is advised to improve maternal and neonatal outcome.

scholarly journals Neonate born with ischemic limb to a COVID-19 positive mother: management and review of literature

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Shahana Perveen ◽  
Karmaine A. Millington ◽  
Suchitra Acharya ◽  
Amit Grag ◽  
Vita Boyar
Keyword(s):  
Differential Diagnosis ◽  
Compartment Syndrome ◽  
Upper Extremity ◽  
Preterm Neonate ◽  
Review Of Literature ◽  
Case Presentation ◽  
Ischemic Limb ◽  
History Of ◽  
Hand Amputation ◽  
Work Up

AbstractObjectivesTo describe challenges in diagnosis and treatment of congenital neonatal gangrene lesions associated with history of maternal coronavirus disease 2019 (COVID-19) infection.Case presentationA preterm neonate was born with upper extremity necrotic lesions and a history of active maternal COVID-19 infection. The etiology of his injury was challenging to deduce, despite extensive hypercoagulability work-up and biopsy of the lesion. Management, including partial forearm salvage and hand amputation is described.ConclusionsNeonatal gangrene has various etiologies, including compartment syndrome and intrauterine thromboembolic phenomena. Maternal COVID-19 can cause intrauterine thrombotic events and need to be considered in a differential diagnosis.

scholarly journals Atypical cutaneous and musculoskeletal manifestation of SARS-CoV-2: ‘COVID-19 toes’ and spasticity in a 48-year-old woman

2021 ◽  
Vol 14 (3) ◽  
pp. e241410
Author(s):  
Avery Kopacz ◽  
Cameron Ludwig ◽  
Michelle Tarbox
Keyword(s):  
Nervous System ◽  
Adult Patient ◽  
Early Identification ◽  
Lower Limbs ◽  
Rare Occurrence ◽  
Cutaneous Manifestations ◽  
Crucial Component ◽  
History Of ◽  
Screening Questions ◽  
Insight Into

Establishing accurate symptomatology associated with novel diseases such as COVID-19 is a crucial component of early identification and screening. This case report identifies an adult patient with a history of clotting dysfunction presenting with rare cutaneous manifestations of COVID-19, known as ‘COVID-19 toes’', previously described predominantly in children. Additionally, this patient presented with possible COVID-associated muscle spasticity of the lower limbs, as well as a prolonged and atypical timeline of COVID-19 infection. The rare occurrence of ‘COVID-19 toes’' in this adult patient suggests that her medical history could have predisposed her to this symptom. This supports the coagulopathic hypothesis of this manifestation of COVID-19 and provides possible screening questions for patients with a similar history who might be exposed to the virus. Additionally, nervous system complaints associated with this disease are rare and understudied, so this novel symptom may also provide insight into this aspect of SARS-CoV-2.

scholarly journals Ancestry and evolution of seasonal migration in the Parulidae

2011 ◽  
Vol 279 (1728) ◽  
pp. 610-618 ◽  
Author(s):  
Benjamin M. Winger ◽  
Irby J. Lovette ◽  
David W. Winkler
Keyword(s):  
Phylogenetic Signal ◽  
Rapid Change ◽  
Large Family ◽  
Seasonal Migration ◽  
Ancestral State ◽  
Migratory Behaviour ◽  
Wood Warbler ◽  
Wood Warblers ◽  
History Of ◽  
The Tropics

Seasonal migration in birds is known to be highly labile and subject to rapid change in response to selection, such that researchers have hypothesized that phylogenetic relationships should neither predict nor constrain the migratory behaviour of a species. Many theories on the evolution of bird migration assume a framework that extant migratory species have evolved repeatedly and relatively recently from sedentary tropical or subtropical ancestors. We performed ancestral state reconstructions of migratory behaviour using a comprehensive, well-supported phylogeny of the Parulidae (the ‘wood-warblers’), a large family of Neotropical and Nearctic migratory and sedentary songbirds, and examined the rates of gain and loss of migration throughout the Parulidae. Counter to traditional hypotheses, our results suggest that the ancestral wood-warbler was migratory and that losses of migration have been at least as prevalent as gains throughout the history of Parulidae. Therefore, extant sedentary tropical radiations in the Parulidae represent losses of latitudinal migration and colonization of the tropics from temperate regions. We also tested for phylogenetic signal in migratory behaviour, and our results indicate that although migratory behaviour is variable within some wood-warbler species and clades, phylogeny significantly predicts the migratory distance of species in the Parulidae.

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