scholarly journals Bacteriological Profile Of Ear Discharge And Their Antibiotic Sensitivity In Chronic Suppurative Otitis Media In Kashmir,India

2012 ◽  
Vol 11 (3) ◽  
pp. 212-216 ◽  
Author(s):  
A Yousuf ◽  
M Malik ◽  
IU Shamas ◽  
Z Beigh ◽  
S Kumari ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Medical Science ◽  
Antibiotic Sensitivity ◽  
Chronic Suppurative Otitis Media ◽  
Diffusion Method ◽  
Sensitivity Testing ◽  
Disk Diffusion Method ◽  
Suppurative Otitis Media ◽  
Staph Aureus

The objective of the study was to study the microflora and the antibiograms of patients with chronic suppurative otitis media (CSOM) in Kashmir,in order to provide a guidelines for making a protocol for empirical antibiotic therapy. Study design:Prospective study Material and methods: This study was conducted on OPD basis in Department of Ear, Nose and Throat and HNS Government medical college Srinagar kashmir from july 2010 to june 1011 and one hundred twenty five(125) patients with unilateral or bilateral active chronic suppurative otitis media were prospectively studied.They had chronic ear discharge and had not received antibiotics for the previous five days. Swabs were taken from discharging ear's and sent to microbiological section of hospital were culture for bacteria was done Antibiotic sensitivity testing was done with standard antibiotic discs using Kirby-bauer disk diffusion method.4 Results:From the Clinical specimens off the 125 patients microbiological culture was positive in 110 specimens. The most common causal organisms isolated were Staphylococcus aureus (48%) including 8% of methcillin resistant staph aureus and Pseudomonas aeruginosa (16%) followed by coagulase negative.Antibiotic sensitivities of staph aureus (other than MRSA) showed that 72% isolates were sensitivity to gentamicin,55% to ciprofloxacin followed by 36% to cephalosporins (cetazidime,ceftriaxone) .For pseudomonas aeruginosa 72% isolates were sensitive to piperacillin/tazobactum 48% to ciprofloxacin and 32% to ceftazidime/ceftriaxone. Of the three antibiotics commonly available as topical eardrops,ciprofloxacin and gentamicin has the highest susceptibility rate. DOI: http://dx.doi.org/10.3329/bjms.v11i3.11731 Bangladesh Journal of Medical Science Vol. 11 No. 03 July’12

scholarly journals Bacteriological and mycological profile of chronic suppurative otitis media

2018 ◽  
Vol 4 (3) ◽  
pp. 754 ◽  
Author(s):  
Nagraj M. ◽  
Premalatha D. E.
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Antibiotic Sensitivity ◽  
Cross Sectional Study ◽  
Chronic Suppurative Otitis Media ◽  
Diffusion Method ◽  
Cross Sectional ◽  
Suppurative Otitis Media ◽  
Sensitivity Pattern

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is the chronic inflammation of the middle ear cleft. It can cause permanent perforation and is famous for its recurrence and persistent infection. Haphazard use of antibiotics and increasing use of newer ones has led to persistent change in microbial flora. The aim of this study was to isolate and identify the bacteria and fungi causing chronic suppurative otitis media and to determine the antibiotic sensitivity pattern of the bacterial isolates.</p><p class="abstract"><strong>Methods:</strong> This is a prospective cross sectional study was done in 70 patients of chronic suppurative otitis media presenting with active ear discharge. Sterile swabs were used to collect pus from discharging ear and sent for culture sensitivity. All organisms isolated were identified according to standard microbiological methods.Antimicrobial susceptibility test was performed using Kirby- Bauer disc diffusion method according to Clinical and Laboratory Standards Institute guidelines.  </p><p class="abstract"><strong>Results:</strong> <em>Staphylococcus aureus </em>and <em>Pseudomonas aeruginosa </em>were the most common organisms isolated in this study. Fungi isolated most commonly was <em>Aspergillus species. Pseudomonas aeruginosa </em>was most sensitive to Piperacillin-Tazobactam, and Gentamycin. <em>Staphylococcus aureus </em>was most sensitive to Linezolid and vancomycin and least sensitive to Erythromycin.</p><p class="abstract"><strong>Conclusions:</strong> <em>Staphylococcus aureus</em> was the most common bacteria isolated and <em>Aspergillus </em>spp was the most common fungi isolated from patients with CSOM. Judicial use of antibiotics is necessary for the prevention of development of antibiotic resistance.</p>

scholarly journals Emergence of antibiotic resistance in bacteria isolated from tubotympanic type of chronic suppurative otitis media in Chhattisgarh

2019 ◽  
Vol 5 (6) ◽  
pp. 1674
Author(s):  
B. R. Singh ◽  
Sagarika Pradhan ◽  
R. Murthy ◽  
Ekta Agrawal ◽  
Rekha Barapatre ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Antibiotic Sensitivity ◽  
Chronic Suppurative Otitis Media ◽  
Causative Organism ◽  
Suppurative Otitis Media ◽  
Major Health Problem ◽  
Common Organism ◽  
Life Threatening

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is a common chronic ear disease and a major health problem in developing countries causing deafness and life threatening complications like meningitis and brain abscess. Early and effective treatment based on the knowledge of causative organism and their antibiotic sensitivity is essential for immediate clinical recovery.</p><p class="abstract"><strong>Methods:</strong> Total of 152 clinically diagnosed patients with CSOM safe were enrolled in the study and two swab of the discharge ear were obtained from each patient under aseptic precaution. Microbiological study was done according to standard operative guidelines.  </p><p class="abstract"><strong>Results:</strong> Out of 152 patients 93 male and 59 were female, majority of the patient seen below 30 year of age. Most common organism found was <em>Staphylococcus aureus </em>(43.2%) and <em>Pseudomonas aeruginosa </em>(27.9%). <em>Staphylococcus aureus</em> was sensitive to vancomycin (98%) and linezolide (100%) and <em>Pseudomonas aeruginosa </em>was found highly sensitive to Imipenem cilastin (84.85%) and Imipenem (66.7%).</p><p class="abstract"><strong>Conclusions:</strong> In our study gram positive <em>Staphylococcus aureus</em> (43.2%) and gram negative bacilli <em>P. aeuroginosa</em> (27.9%) was the most common organism was found and this <em>P. aeruginosa</em> were hospital acquired infections. We found out high resistant to Cefepime, ceftazidime, ciprofloxacin and levofloxacin and aztreonam.</p>

scholarly journals Aerobic bacteriology of Chronic Suppurative Otitis Media (CSOM) in a tertiary care hospital: A retrospective study

2012 ◽  
Vol 7 (2) ◽  
pp. 1-8 ◽  
Author(s):  
RK Sanjana ◽  
YI Singh ◽  
NS Reddy
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Tertiary Care ◽  
Chronic Suppurative Otitis Media ◽  
Diffusion Method ◽  
National Committee ◽  
Care Hospital ◽  
Suppurative Otitis Media ◽  
Sensitivity Pattern

The present study was carried out to determine the aerobic microorganisms involved and their antibiotic sensitivity pattern in patients with Chronic Suppurative Otitis Media (CSOM) and to provide a guideline for empirical antibiotic therapy.Between March 2009 to February 2011, the ear discharge samples submitted at the microbiology laboratory were processed aerobically and all the isolates were included in this study. All organisms were identified morphologically and biochemically by standard laboratory procedures and antibiotic susceptibility pattern was determined by modified Kirby Bauer disc diffusion method as per National Committee for Clinical Laboratory Standard recommendations.Out of a total of 214 samples, microbiological culture was yielded from 202 (94.3%) specimens. Single organism were isolated from 168 (78.5%) of the culture positive specimens, while the remaining 34 (15.9%) had two or more organisms isolated. Pseudomonas aeruginosa 59 (35.1%) was the most common isolate, followed by Staphylococcus aureus 42 (25.0%) including 5 (3%) of the Methicillin Resistant Staphylococcus Aureus (MRSA). Antibiotic sensitivities of Pseudomonas aeruginosa showed that 93.2% isolates were sensitive to tobramycin, whereas, 91.5% isolates were sensitive to ceftazidime and 77.9% to amikacin.Only 50.8% of the isolates of Pseudomonas aeruginosa were sensitive to ciprofloxacin and 25.4% to gentamicin. For Staphylococcus aureus (other than MRSA) 95.2% were sensitive to cloxacillin, 83.3% to gentamicin and 78.5% to erythromycin. Only 07.1% were sensitive to ampicillin and 26.1% to ciprofloxacin.Pseudomonas aeruginosa was the most common isolate followed by Staphylococcus aureus. More than 90% of Pseudomonas and 90% of Staph aureus were sensitive to tobramycin and cloxacillin respectively. Therefore, these two drugs may be included in the formulary to cover the most common aerobic isolates involved in CSOM.Journal of College of Medical Sciences-Nepal, 2011, Vol-7, No-2, 1-8DOI: http://dx.doi.org/10.3126/jcmsn.v7i2.6673

scholarly journals Chronic Suppurative Otitis Media (CSOM): Etiological Agents and Antibiotic Sensitivity Pattern of the Isolates

2015 ◽  
Vol 16 (2) ◽  
pp. 79-82
Author(s):  
Metri C Basavaraj ◽  
P Jyothi
Keyword(s):  
Otitis Media ◽  
Antibiotic Susceptibility ◽  
Clinical Laboratory ◽  
Antibiotic Sensitivity ◽  
Chronic Suppurative Otitis Media ◽  
Diffusion Method ◽  
Susceptibility Pattern ◽  
Suppurative Otitis Media ◽  
Sensitivity Pattern ◽  
Microbiological Techniques

Introduction: Chronic suppurative otitis media (CSOM) remains one of the most common childhood chronic infectious diseases worldwide. It is recognized as an important cause of preventable hearing loss in the developing world. The present study was carried out to determine the etiological agent of CSOM and their antibiotic susceptibility pattern at the teaching hospital in North Karnataka.Methods: Samples were collected from patients in accordance with standard protocols. Organisms were identified by conventional microbiological techniques. Antibiotic susceptibility of the isolates was done by disc diffusion method according Clinical Laboratory Standards Institute (CLSI) guidelines.Results: A total of 159 patients were included in the study, out of which 53.5 % were males. Majority of the patients (85/159) were in the age group of 1-20 years. Pseudomonas was the most common organism causing CSOM, closely followed by Staphylococcus aureus. Pseudomonas were more sensitive to piperacilln-tazobactam (91%), followed by amikacin (80%). Among Staphylococcal isolates sensitivity was more to linezolid (93%), closely followed by piperacilln -tazobactam (88%). 73% of the Gram negative bacilli were sensitive to amikacin and 67% to gentamicinConclusion: Due to the easy availability and widespread use of antibiotics the susceptibility pattern of the pathogenic microorganisms are changing, therefore it is imperative to know the local susceptibility pattern of the causative agents, to treat the infection effectively.J MEDICINE July 2015; 16 (2) : 79-82

scholarly journals Microbiology and antibiotic sensitivity of uncomplicated chronic suppurative otitis media at Dr. George Mukhari Academic Hospital, South Africa

2021 ◽  
Vol 7 (4) ◽  
pp. 565
Author(s):  
Monica Kotu ◽  
Ian Paul Olwoch
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Proteus Mirabilis ◽  
Antibiotic Sensitivity ◽  
Chronic Suppurative Otitis Media ◽  
Older Children ◽  
Suppurative Otitis Media ◽  
Sensitivity Pattern ◽  
Age Range

<p class="abstract"><strong>Background:</strong> The study was conducted to assess the type and frequency of isolation of different microorganisms in uncomplicated chronic suppurative otitis media (CSOM) and their antibiotic sensitivity in our institution.</p><p class="abstract"><strong>Methods:</strong> A total of 88 consecutive patients with unilateral or bilateral active, chronic suppurative otitis media attending outpatient department at DGMAH were included in the study after obtaining an informed consent. There were 55 males (62.5%) and 33 females (37.9%) with age range between 6 months and 76 years. Pus swabs were taken through the perforation site and from the promontory after ear mopping under direct vision.  </p><p><strong>Results:</strong> Children less than 5 years were more affected (23.9%) than older children 5-10 years (13.6%) and 11-15 years (11.45%). One hundred and six microorganisms were isolated from analysis of cultures obtained from 72 patients. Seven cultures were negative (5.9%), 8 specimens were contaminated (6.7%) and 1 specimen was lost (1.1%). <em>Pseudomonas aeruginosa (</em>24.0%<em>) </em>was the most common isolate, followed by <em>Staphylococcus aureus </em>(17%) and <em>Proteus mirabilis </em>(10%). Drug sensitivity pattern showed that Piperacillin-tazobactam was effective against the majority of <em>Pseudomonas aeruginosa </em>isolates at 72%, followed by both Gentamicin and Ceftazidime at 64% and Ciprofloxacin at 48%. <em>Staphylococcus aureus </em>isolates were sensitive to Erythromycin (77%), Cloxacillin and Clindamycin at 72%. <em>Proteus mirabilis </em>was sensitive to Cefuroxime (91%), Co-amoxiclav (72.8%).</p><p class="abstract"><strong>Conclusions:</strong> Isolation rate and susceptibility patterns in CSOM, suggest a need for regular surveillance to monitor antimicrobial resistance and to guide antibacterial therapy.</p><p class="abstract"> </p><h1> </h1>

scholarly journals “The Study of Bacteriological Agents of Chronic Suppurative Otitis Media Aerobic Culture and Antibiotic Sensitivity Testing Pattern at a Tertiary Care Hospital in and around Rajamundry: A cross-sectional study”

2021 ◽  
Vol 7 (4) ◽  
pp. 207-214
Author(s):  
Dr. Neelima Pantagada ◽  
◽  
Dr. Praveen Kavoori ◽  
Keyword(s):  
Otitis Media ◽  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Cross Sectional Study ◽  
Chronic Suppurative Otitis Media ◽  
Care Hospital ◽  
Sectional Study ◽  
Sensitivity Testing ◽  
Cross Sectional ◽  
Suppurative Otitis Media

Introduction: Chronic suppurative otitis media is a chronic infection of the middle ear and mastoidcavity which if not treated leads to partial or total loss of hearing and even life-threateningcomplications like meningitis and Intracranial abscess. Hence it is important to treat the persistentear discharge in CSOM according to the antimicrobial sensitivity of the organism isolated. Methods:This is a prospective cross-sectional study done in 135 clinically diagnosed patients of CSOM at GSLmedical college and General Hospital, Rajamundry, Andhra Pradesh from May 2019 to October 2019.Sterile swabs were used to collect pus from discharging ear and were inoculated onto Blood andMacConkey agar for 24-48 hrs, and identification of organisms was done by using standardbiochemical reactions and antibiotic sensitivity testing done by using modified Kirby- Bauer methodas per CLSI guidelines. Results: A total of 156 strains were isolated from 135 patients in thepresent study of which Pseudomonas aeruginosa and Staphylococcus aureus were amongst the mostisolated pathogens in culture. Imipenem showed the most sensitivity against Pseudomonas,subsequently levofloxacin and piperacillin. Linezolid was the most sensitive versus Staphylococcusensued by ciprofloxacin and cloxacillin. Conclusions: In the present study of Chronic suppurativeotitis media patients, Pseudomonas and Staphylococcus were highly prevalent and showed increasedresistance to beta-lactams and commonly used antimicrobial drugs. Antimicrobials like imipenem,piperacillin, and quinolones are effective against most cases of chronic suppurative otitis media

Bacteriological study and antibiotic sensitivity profile in patients with ear discharge visiting ENT OPD at tertiary care center

2017 ◽  
Vol 4 (1) ◽  
pp. 237
Author(s):  
Kailas R. Patel ◽  
Alpesh D. Fefar ◽  
Paresh J. Khavdu ◽  
Sejal N. Mistry ◽  
Manish R. Mehta
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Middle Ear ◽  
Chronic Otitis Media ◽  
Antibiotic Sensitivity ◽  
Polymyxin B ◽  
Chronic Suppurative Otitis Media ◽  
Purulent Discharge ◽  
Suppurative Otitis Media

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Otitis media (OM) is a big menace in countries like India. Chronic suppurative otitis media (CSOM) is chronic inflammation of middle ear, which affects the tympanic membrane, middle ear mucosa and other middle ear structures characterised by the presence of persistent perforation or persistent mucoid or muco-purulent discharge for at least 8 weeks. Variety of organisms founds in patients suffering from chronic otitis media like, <em>Pseudomonas</em>, <em>Staphylococcus aureus</em>, <em>Proteus mirabilis</em>, <em>Klebsiella pneumonia</em> and <em>Escherichia coli</em> found. The pattern of organisms varies in different geographical areas. The objectives of the study were to isolate bacteria from patients with ear discharge, to find out antibiotic sensitivity of isolated organisms</span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">This is an observational cross sectional study done in the OPD department of otorhinolaryngology, at P.D.U medical college and hospital, Rajkot, for a period of six months from January 2017 to June 2017. A total number 200 patients of both gender between 5 to 74 years who visited the OPD department of otorhinolaryngology with chronic ear discharge taken for study.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Out of 200 patients of 5-74 years with chronic suppurative otitis media were examined and out of this Hundred and twelve (54%) of the patients were males with mean age of 33.44. <em>Pseudomonas aeruginosa</em> was the commonest identified organisms the sensitivity pattern highly favoured Pipercillin, Amikacin and Polymyxin B, Cefoparazone. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Chronic otitis media is more prevalent in males than females. Commonest organisms found were <em>Pseudomonas aeruginosa</em> followed by <em>Staphylococcus aureus. </em>Piperacillin, Amikacin, Gentamicin, Polymyxin B and Cefoperazone were found most effective agents against <em>Pseudomonas aeruginosa</em>.</span></p>

Perbedaan sensitivitas tetes telinga antibiotik terhadap Pseudomonas aeruginosa pada otitis media supuratif kronik

2012 ◽  
Vol 42 (2) ◽  
Author(s):  
Anton Budhi Darmawan ◽  
Dwi Utami Anjarwati
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Test Results ◽  
Sectional Study ◽  
Suppurative Otitis Media ◽  
Number Of Patients ◽  
Significant Difference ◽  
Cochran Test ◽  
Post Hoc

Background: Chronic suppurative otitis media (CSOM) is one infectious disease of the middle ear, most commonly caused by Pseudomonas aeruginosa. A high number of patients come to the ENT outpatient clinic with active benign type of CSOM. The bacteria Pseudomonas aeruginosa is capable of producing biofilm which protects itself from penetration of antibiotics, and therefore creates resistance towards antibiotics and difficult to eradicate. Objective: The aim of this study was to compare the sensitivity levels of chloramphenicol, polymyxin-neomycin, cyprofloxacin and ofloxacine against Pseudomonas aeruginosa in patients with active benign type CSOM in ENT clinic. Method: The method used was across sectional study on 25 patients, from August 2010 until December 2010. Samples were taken withear swab and then put on sensitivity test to chloramphenicol, polymyxin-neomycin, cyprofloxacin andofloxacine using the diffusion disc method. The analysis used in this study was Cochran test. Results: Results showed a significant difference in sensitivity among chloramphenicol (38,70%), polymyxinneomycin(83,87%),cyprofloxacin(90,32%)andofloxacin(58,06%)withp=0,000(p<0,05).PostHocanalysisusing the Mc Nemar indicated that there were significant differences in sensitivity betweenpolymyxin-neomycin to chloramphenicol with p=0,000 (p<0,05), ciprofloxacin to chloramphenicol andciprofloxacin to ofloxacine with p= 0,002, but there were no significant differences between cyprofloxacinto polymyxin-neomycin with p=0,687, polymyxin-neomycin to ofloxacin p=0.057 and ofloxacin tochloramphenicol p=0,109.   There were significant differences in antibiotic ear dropssensitivity to Pseudomonas aeruginosa in patients with active benign type of CSOM. Cyprofloxacin andpolymyxin-neomycin were more sensitive than ofloxacin and chloramphenicol. Keywords: Pseudomonas aeruginosa, active benign type of chronic suppurative otitis media, antibioticear drops.  Abstrak :  Latar belakang: Otitis media supuratif kronik (OMSK) merupakan penyakit infeksi kronik telinga tengah yang sering dijumpai di klinik THT. Penyebab tersering OMSK adalah bakteri Pseudomonasaeruginosa. Pseudomonas aeruginosa mempunyai kemampuan untuk membentuk biofilm yangmelindunginya dari penetrasi antibiotik sehingga menimbulkan resistensi terhadap antibiotik dan sulituntuk eradikasinya. Tujuan: Untuk mengetahui perbandingan tingkat sensitivitas kloramfenikol,polimiksin-neomisin, ciprofloksasin dan ofloksasin terhadap isolat Pseudomonas aeruginosa padapasien OMSK benigna aktif di klinik THT RSMS. Metode: Metode yang digunakan adalah crosssectional terhadap 29 pasien OMSK di klinik THT RSMS periode bulan Agustus 2010 - Desember2010. Pengambilan sampel dilakukan dengan swab telinga. Uji sensitivitas terhadap kloramfenikol,polimiksin-neomisin, ciprofloksasin dan ofloksasin dilakukan dengan metode cakram secara difusi.Analisis yang digunakan dalam penelitian ini adalah Cochran dan analisis post hoc. Hasil: Didapatkansensitivitas kloramfenikol sebesar 38,70%, polimiksin-neomisin sebesar 83,87%, ciprofloksasin sebesar90,32% dan ofloksasin sebesar 58,06% dengan p=0,01 (P<0,05), yang menunjukkan adanya perbedaansensitivitas yang bermakna antara kloramfenikol, polimiksin-neomisin, ciprofloksasin dan ofloksasinterhadap Pseudomonas aeruginosa. Analisis post hoc menggunakan Mc Nemar menunjukkan bahwaterdapat perbedaan sensitivitas yang bermakna antara tetes telinga polimiksin-neomisin terhadapkloramfenikol, dan ciprofloksasin terhadap kloramfenikol p=0,000 (p<0,05), serta terdapat perbedaanyang bermakna antara tetes telinga ciprofloksasin terhadap ofloksasin, p=0,002, tetapi tidak terdapatperbedaan yang bermakna antara ciprofloksasin terhadap polimiksin-neomisin, p=0,687, polimiksinneomisinterhadap ofloksasin p=0,057, dan kloramfenikol terhadap ofloksasin p=0,109. Kesimpulan:Terdapat perbedaan sensitivitas yang bermakna tetes telinga antibiotik terhadap Pseudomonas aeruginosa pada pasien OMSK benigna aktif. Ciprofloksasin dan polimiksin-neomisin tetes telinga mempunyai sensitivitas yang lebih baik dibanding ofloksasin dan kloramfenikol. Kata kunci: Pseudomonas aeruginosa, otitis media supuratif kronik, tetes telinga antibiotik 

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