scholarly journals Effects of exercise on plasma lactic acid and body temperature in man, following a standardized meal

2018 ◽  
Vol 17 (2) ◽  
pp. 270-274
Author(s):  
Tesleem K Babalola ◽  
Udoh Utibe Abasi
Keyword(s):  
Lactic Acid ◽  
Body Temperature ◽  
Statistical Tests ◽  
Medical Science ◽  
Lactate Concentration ◽  
Bicycle Ergometer ◽  
Mean Value ◽  
Plasma Lactate ◽  
Post Exercise ◽  
Before And After

Background: The effects of exercise on plasma lactic acid level and body temperature following a standardized meal were carried out on 20 healthy young individuals (aged between 18 and 29 yrs.), consisting of 10 males and 10 females. The physical fitness of the subjects was determined measuring their blood pressure, pulse rate and other physical examinations.Methodology: Each subject was made to ride the bicycle ergometer for 6mins, at a rhythmic cadence of 50revolution/ min via 100beats metronome counts. Blood samples were collected before and after the exercise to analyze for the pre and post exercise plasma lactate levels. Pre and post-exercise values for body temperature were also measured. Statistical tests were carried out at 95% CI (P=0.05).Result: The result obtained showed that exercise causes a statistically significant increase (p< 0.05) in both plasma lactate concentration (from a pre-exercise mean value of 0.98 ±0.07mmol/L to post- exercise mean value of 2.84 ±0.21mmol/L) and body temperature (from a mean value of 36.45 ±0.130C before exercise to a mean value of 36.91 ±0.190C after exercise).Conclusion: There was a statistically significant increase in plasma lactateand body temperature because of exposure to exercise which is in line with findings from most previous studies.Bangladesh Journal of Medical Science Vol.17(2) 2018 p.270-274

Diving and swimming performance of white whales, Delphinapterus leucas: an assessment of plasma lactate and blood gas levels and respiratory rates.

1997 ◽  
Vol 200 (24) ◽  
pp. 3091-3099 ◽  
Author(s):  
S A Shaffer ◽  
D P Costa ◽  
T M Williams ◽  
S H Ridgway
Keyword(s):  
High Speed ◽  
Swimming Performance ◽  
Lactate Concentration ◽  
Delphinapterus Leucas ◽  
Breath Hold ◽  
Plasma Lactate ◽  
Post Exercise ◽  
Test Platform ◽  
Plasma Lactate Concentration ◽  
Breath Hold Duration

The white whale Delphinapterus leucas is an exceptional diver, yet we know little about the physiology that enables this species to make prolonged dives. We studied trained white whales with the specific goal of assessing their diving and swimming performance. Two adult whales performed dives to a test platform suspended at depths of 5-300 m. Behavior was monitored for 457 dives with durations of 2.2-13.3 min. Descent rates were generally less than 2 m s-1 and ascent rates averaged 2.2-3 m s-1. Post-dive plasma lactate concentration increased to as much as 3.4 mmol l-1 (4-5 times the resting level) after dives of 11 min. Mixed venous PO2 measured during voluntary breath-holds decreased from 79 to 20 mmHg within 10 min; however, maximum breath-hold duration was 17 min. Swimming performance was examined by training the whales to follow a boat at speeds of 1.4-4.2 m s-1. Respiratory rates ranged from 1.6 breaths min-1 at rest to 5.5 breaths min-1 during exercise and decreased with increasing swim speed. Post-exercise plasma lactate level increased to 1.8 mmol l-1 (2-3 times the resting level) following 10 min exercise sessions at swimming speeds of 2.5-2.8 m s-1. The results of this study are consistent with the calculated aerobic dive limit (O2 store/metabolic rate) of 9-10 min. In addition, white whales are not well adapted for high-speed swimming compared with other small cetaceans.

Onset of submaximal exercise in thoroughbred horses

1987 ◽  
Vol 65 (10) ◽  
pp. 2513-2518 ◽  
Author(s):  
Jean-Michel Weber ◽  
Wade S. Parkhouse ◽  
Geoffrey P. Dobson ◽  
Joyce C. Harman ◽  
David H. Snow ◽  
...  
Keyword(s):  
Heart Rate ◽  
Steady State ◽  
Cardiovascular Response ◽  
Lactate Concentration ◽  
Mean Value ◽  
Plasma Lactate ◽  
Work Intensity ◽  
Thoroughbred Horses ◽  
Plasma Lactate Concentration ◽  
Intensity Of Exercise

Plasma lactate concentration, hematocrit, and heart rate were measured during a 40-min trot (3–4 m/s, 6% incline) and a 15-min canter (6.5 m/s, 0% incline) in catheterized thoroughbred horses running on a treadmill to characterize the transient changes in plasma lactate concentration during the onset of exercise, and to determine if and when a steady state was established. The intensity of exercise had an effect on the pattern of changes observed for the three variables investigated. Mean hematocrit rose from 38.5% at rest to 52.0% after a 4-min walk (1.6 m/s) and to 57.7% after 3 min of subsequent trotting (4 m/s). The highest mean value of 58.7% was reached after 3 min of cantering. A slow but significant decrease in hematocrit was measured between the time maximum levels were attained for each work intensity and the end of exercise. During the onset of submaximal work, plasma lactate concentration, hematocrit, and heart rate all reached a maximum simultaneously. The rapid cardiovascular response of thoroughbreds (strong hematocrit increase and heart-rate overshoot) did not prevent them from temporarily relying on anaerobic metabolism, as shown by a marked lactate overshoot before a steady state was established. The observed changes in lactate concentration are explained by a model predicting lactate fluxes to and from the plasma compartment during the transition from the resting steady state to the exercise steady state. Biopsies of the middle gluteal muscle were taken before and after the canter protocol to measure the metabolic intermediates of the glycogenolytic pathway. The resting and postexercise concentrations of these intermediates were not different except for a 30% reduction in glycogen. Aerobic glycogenolysis was the main pathway for energy metabolism in the middle gluteus and, as in plasma, a metabolic steady state was established in this muscle.

Deficiency of glycerol kinase (EC 2.7.1.30).

1983 ◽  
Vol 29 (4) ◽  
pp. 718-722 ◽  
Author(s):  
A Eriksson ◽  
S Lindstedt ◽  
L Ransnäs ◽  
L von Wendt
Keyword(s):  
Blood Glucose Concentration ◽  
Lactate Concentration ◽  
Glycerol Kinase ◽  
Bicycle Ergometer ◽  
Gas Chromatography Mass Spectrometry ◽  
Glycerol Concentration ◽  
Plasma Lactate ◽  
Cultured Fibroblasts ◽  
Plasma Lactate Concentration ◽  
Large Peak

Abstract We describe the case of a 10-year-old boy who had been admitted on several occasions with a diagnosis of gastroenteritis. He had been severely ill, and on one occasion lost consciousness. He had a metabolic acidosis on these occasions. Examination of the urine by gas chromatography-mass spectrometry showed a large peak, identified as glycerol. The concentration of glycerol in the urine was 40-280 mmol/L and the concentration in plasma about 2 mmol/L. He was subjected to a fast of 21 h, at the end of which he expressed feelings of discomfort and nausea, began vomiting, and became somnolent. During this period the blood glucose concentration was only slightly decreased, the plasma glycerol concentration increased to 4.9 mmol/L, and the plasma lactate concentration increased to 3.8 mmol/L. During work on a bicycle ergometer for 35 min (40 W) he complained of muscle pain and became nauseated, but there was no significant increase in the concentration of plasma glycerol. The activity of glycerol kinase (EC 2.7.1.30) in leukocytes and cultured fibroblasts was less than 1% of the value for healthy subjects.

scholarly journals The Effect of Disaster Management Education on Mother’s Under Five Preparedness Facing Floods In Aceh Province

2021 ◽  
Vol 9 (E) ◽  
pp. 1032-1035
Author(s):  
Rachmawati Rachmawati ◽  
Rosi Novita ◽  
Ida Fitria
Keyword(s):  
Disaster Management ◽  
Disaster Preparedness ◽  
Management Education ◽  
Statistical Tests ◽  
Mean Value ◽  
T Test ◽  
Under Five ◽  
Significant Difference ◽  
Before And After ◽  
Post Test

BACKGROUND: The flood disaster has had various impacts on the people in Aceh. One of the groups prone to flooding is mothers with toddlers. Efforts should be made to increase capacity, understanding, and knowledge through education and education for disaster preparedness to reduce the risk of occurring. AIM: Analyzing the effect of disaster management education on the Preparedness of mothers under five in Aceh. METHODS: This type of research is a quasi-experimental study using the One-Group Pretest-Posttest. The sample in this study was 51 mothers of children under five who were willing to sample and resided in two flood-affected villages. Data collection on the Preparedness of mothers under five in this study was carried out using pre-test and post-test questionnaires before and after the provision of disaster education. Data analysis using bivariate used dependent T-test and correlation analysis used Rank Spearman correlation. RESULTS: The results showed a significant difference in the mean value of knowledge, attitudes, and Preparedness of under-five mothers before and after receiving education about disasters, as evidenced by statistical tests using the dependent t-test p < 0.05. Measurement of the pre-test and post-test scores on the average increase in knowledge from before 89.45 to 94.53 after education provision. The attitude variable also increased on average from 39.43 to 48.40 after the provision of education. The preparedness variable also increased on average from 50.69 to 58.28 after the provision of education. CONCLUSION: Disaster management education has provided increased knowledge, attitudes, and Preparedness for mothers under five to flood disasters.

Suppression Of Exercise-Induced Plasminogen Activator And Plasma Renin Activity Following Aspirin Ingestion

1981 ◽  
Author(s):  
D H Osmond ◽  
A M Hedlin ◽  
A Y Loh ◽  
D Sakac ◽  
R R Topp
Keyword(s):  
Plasma Renin Activity ◽  
Plasminogen Activator ◽  
Plasma Renin ◽  
Bicycle Ergometer ◽  
Renin Activity ◽  
Post Exercise ◽  
Before And After ◽  
Exercise Induced ◽  
Aspirin Ingestion

The influence of aspirin on the fibrinolytic and renin systems was studied in 10 healthy young men, who served as their own controls. Basal blood samples were obtained after a 15-minute rest, immediately after exercise, and following a 15-min post-exercise rest. Later, (7-14 days) 1250 mg aspirin was ingested 1 hr. before test samples were obtained, as before. Exercise on a bicycle ergometer induced doubling of the resting heart rate within 2 min., and was continued for 3 min. longer. Aspirin induced a significant reduction in the level of plasminogen activator, before and after exercise, and also some decrease in hemoglobin and hematocrit levels. Exercise almost doubled the baspl plasma renin activity (PRA, angiotensin I, ng/ml plasma/hr., by radioimmunoassay) in the control and aspirin experiments. Aspirin did not significantly blunt this exercise-induced rise in PRA. However, after 15-minute rest, the control PRA remained elevated, while the postaspirin PRA was 37% below it (p < 0.025). After cold activation of the plasmas (-4°C, 72 hr.), the PRA increment over corresponding non-activated samples was used to estimate “prorenin”. Prorenin as % of active renin before aspirin was 347.2, 210.5, and 210.8, for the basal and 2 post-exercise periods respectively; after aspirin the values were 460.5, 354.9, and 353.4. Clearly, exercise depresses the proportion of prorenin, suggesting an exercise-induced enhancement of prorenin conversion, possibly related to the exercise-induced stimulation of the fibrinolytic system. After aspirin, all 3 prorenin percentages are higher, implying that it interferes with prorenin conversion. Thus, exercise increases both fibrinolysis and PRA. The increase in PRA could be due in part to fibrinolytic enzyme conversion of prorenin (plasmin activates prorenin in vitro). Aspirin suppresses plasminogen activator, and thus prorenin activation.

Hyperthermia, lactic acid infusion, and the composition of arterial blood and cerebrospinal fluid

1962 ◽  
Vol 202 (6) ◽  
pp. 1049-1054 ◽  
Author(s):  
S. C. Alexander ◽  
R. D. Workman ◽  
C. J. Lambertsen
Keyword(s):  
Cerebrospinal Fluid ◽  
Lactic Acid ◽  
Body Temperature ◽  
Lactate Concentration ◽  
Respiratory Control ◽  
Acid Infusion ◽  
Arterial Blood ◽  
Csf Lactate ◽  
Ph Scale ◽  
End Tidal

The effect of an approximately 2 C rise in body temperature on arterial and cerebrospinal fluid (CSF) lactate concentration, pH, Pco2, and [HCO3–] was studied in eight artificially ventilated dogs maintained at constant end-tidal Pco2. The combined effect of hyperthermia and intravenous lactic acid infusion on CSF lactate concentration was also studied in three additional dogs. In normothermia the lactate concentration, Pco2, and [HCO3–] in the CSF were significantly higher than in arterial blood, whereas CSF pH was significantly lower than arterial pH. Rise in body temperature at constant end-tidal (and arterial) Pco2 resulted in no significant change in lactate concentration of blood or CSF, a parallel fall in arterial and CSF pH, a decrease in both arterial and CSF [HCO3–], and a rise in CSF PCO2. An intravenous lactic acid infusion had no measurable effect on CSF lactate concentration. A general entrance of lactate ion into the CSF from blood or brain does not appear to play a role in respiratory control during hyperthermia. The possibility remains that lactate enters CSF during exercise but from the brain rather than from the circulating blood. Limitations of the conventional pH scale preclude assessment of changes in hydrogen ion activity during hyperthermia.

Effect of dichloroacetate on lactate concentration in exercising humans

1989 ◽  
Vol 66 (2) ◽  
pp. 591-597 ◽  
Author(s):  
F. Carraro ◽  
S. Klein ◽  
J. I. Rosenblatt ◽  
R. R. Wolfe
Keyword(s):  
Dehydrogenase Activity ◽  
Pyruvate Dehydrogenase ◽  
Tissue Oxygenation ◽  
Lactate Concentration ◽  
Bicycle Ergometer ◽  
Plasma Lactate ◽  
Exercise Load ◽  
Plasma Lactate Concentration ◽  
Oxidation Of Glucose ◽  
Exercise In Humans

The precise mechanism responsible for the increase in plasma lactate concentration during exercise in humans is not known. We have used dichloroacetate to test the hypothesis that a limitation in pyruvate dehydrogenase activity is responsible for the rise in plasma lactate. Dichloroacetate stimulates the activity of pyruvate dehydrogenase, which is normally the regulatory enzyme in the oxidation of glucose when tissue oxygenation is adequate. Six subjects were studied twice according to a randomized, crossover protocol, involving one test with saline infusion and another with dichloroacetate infusion. Exercise load on a bicycle ergometer was increased progressively until exhaustion. Blood samples were drawn each minute throughout exercise and periodically throughout 120 min of recovery. Dichloroacetate significantly lowered the lactate concentration during exercise performed at less than 80% of the average maximal O2 consumption. The peak concentration of lactate at exhaustion was not affected by dichloroacetate treatment, but dichloroacetate did lower lactate concentration throughout recovery. These results suggest that a limitation in pyruvate dehydrogenase activity contributes to the increase in plasma lactate during submaximal exercise and recovery.

Bone and shell contribution to lactic acid buffering of submerged turtles Chrysemys picta bellii at 3°C

2000 ◽  
Vol 278 (6) ◽  
pp. R1564-R1571 ◽  
Author(s):  
Donald C. Jackson ◽  
Carlos E. Crocker ◽  
Gordon R. Ultsch
Keyword(s):  
Lactic Acid ◽  
Lactate Concentration ◽  
Plasma Lactate ◽  
Acid Base ◽  
Bone Ash ◽  
Chrysemys Picta Bellii ◽  
Bone Water ◽  
Plasma Lactate Concentration ◽  
Plasma Calcium Concentration ◽  
Acid Base Status

To evaluate shell and bone buffering of lactic acid during acidosis at 3°C, turtles were submerged in anoxic or aerated water and tested at intervals for blood acid-base status and plasma ions and for bone and shell percent water, percent ash, and concentrations of lactate, Ca2+, Mg2+, Pi, Na+, and K+. After 125 days, plasma lactate concentration rose from 1.6 ± 0.2 mM (mean ± SE) to 155.2 ± 10.8 mM in the anoxic group but only to 25.2 ± 6.4 mM in the aerated group. The acid-base state of the normoxic animals was stable after 25 days of submergence. Plasma calcium concentration ([Ca2+]) rose during anoxia from 3.2 ± 0.2 to 46.0 ± 0.6 mM and [Mg2+] from 2.7 ± 0.2 to 12.2 ± 0.6 mM. Both shell and bone accumulated lactate to concentrations of 135.6 ± 35.2 and 163.6 ± 5.1 mmol/kg wet wt, respectively, after 125 days anoxia. Shell and bone [Na+] both fell during anoxia but the fate of this Na+ is uncertain because plasma [Na+] also fell. No other shell ions changed significantly in concentration, although the concentrations of both bone calcium and bone potassium changed significantly. Control shell water (27.8 ± 0.6%) was less than bone water (33.6 ± 1.1%), but neither changed during submergence. Shell ash (44.7 ± 0.8%) remained unchanged, but bone ash (41.0 ± 1.0%) fell significantly. We conclude that bone, as well as shell, accumulate lactate when plasma lactate is elevated, and that both export sodium carbonate, as well as calcium and magnesium carbonates, to supplement ECF buffering.

scholarly journals The Effect of Sports Rules Amendments on Exercise Intensity during Taekwondo-Specific Workouts

2020 ◽  
Vol 17 (18) ◽  
pp. 6779
Author(s):  
Michał Janowski ◽  
Jacek Zieliński ◽  
Monika Ciekot-Sołtysiak ◽  
Agata Schneider ◽  
Krzysztof Kusy
Keyword(s):  
Blood Lactate ◽  
Lactate Concentration ◽  
Breathing Rate ◽  
Exercise Tests ◽  
Post Exercise ◽  
Kinematic Data ◽  
Exercise Response ◽  
Before And After ◽  
Rule Changes ◽  
Lactate Peak

We aimed to compare the change in exercise response to taekwondo-specific circuit workouts before and after competition rule amendments. A total of 240 workouts in 15 elite athletes were analyzed over two years. Physiological and kinematic data were gathered with the wireless Bioharness system along with capillary blood samples for lactate concentration. Progressive exercise tests until exhaustion were periodically performed to obtain reference data. The rule changes resulted in significant increases (mainly medium or large effects) in the physiological (2.9–14.4%) and kinematic (4.8–10.1%) response to taekwondo-specific workouts. The largest increases were for peak breathing rate (12.0%), energy expenditure (6.6%), blood lactate immediately after exercise (10.2%) and at the 30th min of recovery (14.4%), and peak kinematic activity (10.1%). Significant differences between taekwondo-specific workouts and tournament combats persisted after the shift from old to new rules, ranging from 2.4 to 38.5% for physiological and from 2.9 to 15.5% for kinematic variables. The largest workout–combat differences were revealed for post-exercise (15.9%) and recovery (38.5%) blood lactate, peak (−15.8%) and relative (−15.0%) breathing rate, and mechanical (13.5%) and physiological (14.2%) intensity. Our study suggests that the rule amendments significantly modify the exercise response to discipline-specific workouts and that taekwondo-specific training sessions do not fully recreate the tournament demands in terms of physiological and kinematic load.

Sign in / Sign up

Export Citation Format

Share Document