scholarly journals A Further Comprehensive Review on the Phytoconstituents from the Genus Erythrina

2020 ◽  
Vol 23 (1) ◽  
pp. 65-77 ◽  
Author(s):  
Mohammad Musarraf Hussain
Keyword(s):  
Chemical Structure ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Pharmaceutical Journal ◽  
Significant Source ◽  
Comprehensive Review ◽  
Chemical Structures ◽  
Previous Review

Erythrina is a significant source of phytoconstituents. The aim of this review is to solicitude of classification, synthesis, and phytochemicals with biological activities of Erythrina. In our previous review on this genus (Hussain et. al., 2016a) fifteen species (Erythrina addisoniae, E. caribeae, E. indica, E. lattisima, E. melanacantha, E. mildbraedii, E. poeppigiama, E. stricta, E. subumbrans, E. veriagata, E. vespertilio, E. velutina, E. zeberi, E. zeyheri and E. americana) have been studied and 155 molecules with chemical structures were reported. A further comprehensive review was done upon continuation on the same genus and thirteen species (E. abyssinica, E. arborescens, E. berteroana, E. burttii, E. caffra, E. coralloids, E. crista-galli, E. fusca, E. herbaceae, E. lysistemon, E. mulungu, E. speciosa and E. tahitensis) of Erythrina have been studied and 127 compounds are reported as phytoconstituents with their chemical structure in this review. Erythrina crista-galli and E. lysistemon consist of highest number of chemical constituents. Bangladesh Pharmaceutical Journal 23(1): 65-77, 2020

scholarly journals Chemical constituents of the Rhizomes of Curcuma zedoaria

2021 ◽  
Vol 5 (2) ◽  
pp. first
Author(s):  
Truong Nhat Van Do ◽  
Hai Xuan Le ◽  
Tho Huu Le ◽  
Mai Thanh Thi Nguyen
Keyword(s):  
Medicinal Plants ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Preparative Thin Layer Chromatography ◽  
Chemical Constituent ◽  
Scientific Data ◽  
Curcuma Zedoaria ◽  
Etoac Extract ◽  
Chemical Structures ◽  
Pure Compounds

Curcuma zedoaria (Berg.), belongs to the Zingiberaceae family, is one of the medicinal plants that is found in Southeast Asia. This plant is known as “Nghe tim” in Vietnam; and a decoction of its rhizomes has been used traditionally for the cure flatulence, fatigue, and hepatitis. Previously, some studies on the chemical constituent of the rhizomes of C. zedoaria have reported plenty of curcuminoids and sesquiterpenoids together with their derivatives, which have shown a lot of various bioactivities such as antiproliferative characteristic, anti-ulcer, antioxidant and antibacterial potential. By chromatography column method along with preparative thin layer chromatography on a normal phase silica gel on the EtOAc extract of the rhizomes of Curcuma zedoaria, we have isolated five pure compounds. Their chemical structures have been elucidated by NMR techniques and comparison with publishing data that have determined to be gajustulactone A (1), isozedoarondiol (2), neolitacumone (3), β-sitosterol (4), and β-stigmasterol (5). The results of this study have contributed to the scientific data system on the chemical composition of Vietnamese medicinal plants, especially the rhizomes of Curcuma zedoaria grown in Tinh Bien, An Giang. Therefore, there is more evidence to continue screening studies to detect interesting biological activities from this species.

scholarly journals Tectona grandis L.f : A comprehensive review on its patents, chemical constituents, and biological activities

2021 ◽  
Author(s):  
Syed Mohammed Basheeruddin Asdaq ◽  
Naira Nayeem ◽  
Abida ◽  
Md. Tauquir Alam ◽  
Saleh I. Alaqel ◽  
...  
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Tectona Grandis ◽  
Comprehensive Review ◽  
Tectona Grandis L.F

scholarly journals A Comprehensive Review on the Phytoconstituents from Six Species of the Genus Amaranthus

2019 ◽  
Vol 22 (1) ◽  
pp. 117-124 ◽  
Author(s):  
Mohammad Musarraf Hussain
Keyword(s):  
Pharmaceutical Journal ◽  
Comprehensive Review ◽  
Chemical Structures

The objective of this review is to consider the phytoconstituents from six species under the genus Amaranthus (A. retroflexus, A. spinosus, A. viridis, A. caudatus, A. hypocondriacus and A. tricolor). A total of sixty five (1-65) phytoconstituents with chemical structures have been reported in this study. A. retroflexus consists of high number of reported phytoconstituents. Bangladesh Pharmaceutical Journal 22(1): 117-124, 2019

Seco-tetracyclic and Seco-pentacyclic Triterpenoids from Nature: Phytochemistry, Biological Activity: A Review

2021 ◽  
Vol 18 ◽  
Author(s):  
Yingkai Liu ◽  
Yuqing Jian ◽  
Mengru Cao ◽  
Bin Wang ◽  
Yixing Qiu ◽  
...  
Keyword(s):  
Natural Products ◽  
Biological Activity ◽  
Special Class ◽  
Biological Activities ◽  
Pentacyclic Triterpenoids ◽  
Comprehensive Review ◽  
Chemical Structures

: Seco-tetracyclic and seco-pentacyclic triterpenoids are a special class of triterpenoids with ring/rings cleaved on the original skeleton structures. A class of important triterpene derivatives, seco-tetracyclic and seco-pentacyclic triterpenoids, have long stimulated the interest and attention of botanists and natural products chemists. There is no systematic and comprehensive review for them. This review is focused on the phytochemical investigations and biological activities of seco-tetracyclic and seco-pentacyclic triterpenoids from nature, covering the literature from 2000-2019. This review describes 310 seco-tetracyclic and 139 seco-pentacyclic triterpenoids discovered from 154 species belong to 97 genera, which cover the chemical structures, types, sources, and bioactivities of compounds. The literature from 2000-2019 is reviewed and 208 references are cited.

scholarly journals Recent Advances in Kaempferia Phytochemistry and Biological Activity: A Comprehensive Review

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2396 ◽  
Author(s):  
Elshamy ◽  
Mohamed ◽  
Essa ◽  
Abd-ElGawad ◽  
Alqahtani ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Principal Component ◽  
Comprehensive Review ◽  
Traditional Uses ◽  
Biological Studies ◽  
Tract Infections

Background: Plants belonging to the genus Kaempferia (family: Zingiberaceae) are distributed in Asia, especially in the southeast region, and Thailand. They have been widely used in traditional medicines to cure metabolic disorders, inflammation, urinary tract infections, fevers, coughs, hypertension, erectile dysfunction, abdominal and gastrointestinal ailments, asthma, wounds, rheumatism, epilepsy, and skin diseases. Objective: Herein, we reported a comprehensive review, including the traditional applications, biological and pharmacological advances, and phytochemical constituents of Kaempheria species from 1972 up to early 2019. Materials and methods: All the information and reported studies concerning Kaempheria plants were summarized from library and digital databases (e.g., Google Scholar, Sci-finder, PubMed, Springer, Elsevier, MDPI, Web of Science, etc.). The correlation between the Kaempheria species was evaluated via principal component analysis (PCA) and agglomerative hierarchical clustering (AHC), based on the main chemical classes of compounds. Results: Approximately 141 chemical constituents have been isolated and reported from Kaempferia species, such as isopimarane, abietane, labdane and clerodane diterpenoids, flavonoids, phenolic acids, phenyl-heptanoids, curcuminoids, tetrahydropyrano-phenolic, and steroids. A probable biosynthesis pathway for the isopimaradiene skeleton is illustrated. In addition, 15 main documented components of volatile oils of Kaempheria were summarized. Biological activities including anticancer, anti-inflammatory, antimicrobial, anticholinesterase, antioxidant, anti-obesity-induced dermatopathy, wound healing, neuroprotective, anti-allergenic, and anti-nociceptive were demonstrated. Conclusions: Up to date, significant advances in phytochemical and pharmacological studies of different Kaempheria species have been witnessed. So, the traditional uses of these plants have been clarified via modern in vitro and in vivo biological studies. In addition, these traditional uses and reported biological results could be correlated via the chemical characterization of these plants. All these data will support the biologists in the elucidation of the biological mechanisms of these plants.

scholarly journals Note on forgotten topological index of chemical structure in drugs

2016 ◽  
Vol 1 (2) ◽  
pp. 369-374 ◽  
Author(s):  
Harishchandra S. Ramane ◽  
Raju B. Jummannaver
Keyword(s):  
Chemical Structure ◽  
Topological Index ◽  
Pharmaceutical Journal ◽  
Chemical Structures ◽  
The One

AbstractThe forgotten topological index of a graph G is defined as the sum of the cube of the degrees of its vertices. In the recent paper [6], [W. Gao et al. (2016), Forgotten topological index of chemical structure in drugs, Saudi Pharmaceutical Journal, 24, 258-264], the forgotten topological index of some chemical structures has been obtained. In this note, we correct their result regarding triangular benzenoid. Also, we have given the expression for the forgotten topological index of graphene structure which is more compact than the one was obtained in the paper above.

A link between chemical structure and biological activity in triterpenoids

2021 ◽  
Vol 16 ◽  
Author(s):  
Zang Li ◽  
Hao Xu ◽  
Chao Huang ◽  
Cunqin Wang ◽  
Rongbin Wang ◽  
...  
Keyword(s):  
Chemical Structure ◽  
Biological Activities ◽  
Chemical Structures ◽  
Pentacyclic Triterpenoid ◽  
Medicinal Value ◽  
Anti Cancer ◽  
Cell Death Signaling ◽  
Cancer Activity ◽  
Novel Therapeutic ◽  
Skeleton Structure

Background: Plants with triterpenoid compounds in nature have various biological activities and are reported in many scientific works of literature. Triterpenoids are compounds that draw the attention of scientists because of their wide source, wide variety, high medicinal value, and anti-tumor properties. However, a lack of approach to understand their chemical structures has limited the fundamental comprehension of these compounds in cancer cell therapy. Objective: To seek anti-cancer activity of the structures of triterpenoid compounds and their derivatives, we summarized a number of plants and their derivatives that are a source of potential novel therapeutic anti-cancer agents. Methods: This work focuses on relevant 1036 patents and references that detail the structure of organic compounds and derivatives for the treatment of tumors. Result: Compared to tetracyclic triterpenoid, pentacyclic triterpenoid has contributed more to improve the autophagic signaling pathways of cancer cells. Conclusion: The heterogenous skeleton structure of triterpenoids impaired the programmed cell death signaling pathway in various cancers

scholarly journals The Distribution of Asterosaponins, Polyhydroxysteroids and Related Glycosides in Different Body Components of the Far Eastern Starfish Lethasterias fusca

Marine Drugs ◽  
2019 ◽  
Vol 17 (9) ◽  
pp. 523 ◽  
Author(s):  
Roman S. Popov ◽  
Natalia V. Ivanchina ◽  
Alla A. Kicha ◽  
Timofey V. Malyarenko ◽  
Boris B. Grebnev ◽  
...  
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Protective Role ◽  
Individual Variability ◽  
Coelomic Fluid ◽  
Pyloric Caeca ◽  
Chemical Structures ◽  
Body Components ◽  
Distribution In The Organism ◽  
Far Eastern

Glycoconjugated and other polar steroids of starfish have unique chemical structures and show a broad spectrum of biological activities. However, their biological functions remain not well established. Possible biological roles of these metabolites might be indicated by the studies on their distribution in the organism–producer. In order to investigate the localization of polar steroids in body components of the Far Eastern starfish Lethasterias fusca, chemical constituents of body walls, gonads, stomach, pyloric caeca, and coelomic fluid were studied by nanoflow liquid chromatography/mass spectrometry with captive spray ionization (nLC/CSI–QTOF–MS). It has been shown that the levels of polar steroids in the studied body components are qualitatively and quantitatively different. Generally, the obtained data confirmed earlier made assumptions about the digestive function of polyhydroxysteroids and protective role of asterosaponins. The highest level of polar steroids was found in the stomach. Asterosaponins were found in all body components, the main portion of free polyhydroxysteroids and related glycosides were located in the pyloric caeca. In addition, a great inter-individual variability was found in the content of most polar steroids, which may be associated with the peculiarities in their individual physiologic status.

Effects to Active Composition of Tibetan Medicinal Materials with Twinkling Ultrasonic Cavitation

2010 ◽  
Vol 152-153 ◽  
pp. 1660-1664
Author(s):  
Bao Qiang Wang ◽  
Liang Liang Yang
Keyword(s):  
Chemical Structure ◽  
Chemical Constituents ◽  
Sound Field ◽  
High Energy ◽  
Ultrasonic Extraction ◽  
Tibetan Medicine ◽  
Active Ingredients ◽  
Extraction Technology ◽  
Chemical Structures ◽  
The Impact

To get higher rate of medicinal active ingredients of Tibetan medicine, the high-energy ultrasonic extraction technology is used. But the effect mechanism of acoustic cavitation to the chemical structure of the drugs is not clear yet. It is because that the theoretical and experimental researches are not enough. The research contents: the impact mechanism of HI ultrasound to the chemical structure of extracts should be tested comparing with other extraction technology, and the chemical composition of extracts with the different sound field parameters, media conditions, and process parameters. The methods: the chemical structures of active ingredients of extracts are detected by means of HPLC with the HI ultrasonic and reflux boiling extraction technologies; ultrasonic type, frequency and power density are repeatedly adjust respectively; the ③changes of the chemical constituents of the Tibetan medicine extracts are detected. The optimized acoustic parameters are obtained. Based on the findings above, the symmetrical collective and high intensity ultrasound is established. The results: the bio-pharmaceutical active ingredients of Tibetan medicine will not be compromised with the ultrasonic extraction; the ability of SCHIU extraction of Tibetan medicine is 3 to 4 times more than conventional ultrasound extraction with the same extracting rate.

Biodegradation of Phenol: Mini Review

2020 ◽  
Vol 6 (2) ◽  
pp. 53-61
Author(s):  
Razan Saraireh ◽  
Batool Asasfeh ◽  
Mutaz Saraireh ◽  
Kholoud Shiyyab ◽  
Rawan Shawawreh
Keyword(s):  
Aromatic Compounds ◽  
Metabolic Pathways ◽  
Chemical Structure ◽  
Biological Degradation ◽  
Comprehensive Review ◽  
Chemical Structures ◽  
Determining Factors ◽  
Pure Cultures ◽  
Physical And Chemical ◽  
Number Of Bacteria

This paper is a comprehensive review related to the biological degradation of phenol by microorganisms. The aromatic compound, phenol or hydroxybenzene, is produced industrially or naturally. Many microorganisms that are able to biodegrade phenol have been isolated and at the same time, the metabolic pathways responsible for these metabolic processes have been determined. A large number of bacteria were studied in detail especially, pure cultures as well as the pathways of aerobic phenol metabolism and the enzymes involved. Phenol oxygenation occurred as the initial steps through phenol hydroxylase enzymes leading to formation of catechol, pursued by the splitting of the adjacent ring or in between the two groups of catechol hydroxyls. Thus, the physical and chemical environments plus the chemical structures that affecting biodegradation processes are important determining factors for combating of pollution. This nature of chemical structure for the other aromatic compounds is also a main decisive factor of biodegradability.

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