Neuro-ophthalmologic manifestations of corona virus disease (COVID-19): A case series

2021 ◽  
pp. 42-44
Author(s):  
Mohammad Afzal Mahfuzullah ◽  
Md Sharfuddin Ahmed ◽  
Md Zafar Khaled ◽  
Nuzhat Choudhury ◽  
Shah Noor Hassan ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Optic Neuropathy ◽  
Virus Disease ◽  
Case Series ◽  
Recovery Phase ◽  
Acute Illness ◽  
Corona Virus ◽  
Nerve Dysfunction ◽  
Late Recovery ◽  
Phase Optic

Manifold neuro-ophthalmological signs & symptoms have been described in association with corona virus disease 19 (COVID-19). These presenting manifestations probably due to the result of a range of pathophysiological mechanisms throughout the course from acute illness to recovery phase & late recovery phase. Optic nerve dysfunction like optic neuropathy is associated with post COVID-19 infection. In this case series we want to highlight about the course, sequelae & association of optic neuropathy in COVID-19 patients. BSMMU J 2021; 14 (COVID -19 Supplement): 42-44

CASE SERIES: A SPECTRUM OF FUNGAL INFECTIONS IN COVID-19

2021 ◽  
pp. 29-30
Author(s):  
Venkatesh B. C. ◽  
Rajendra Rao K. M. ◽  
K. N. Mohan Rao
Keyword(s):  
Diabetes Mellitus ◽  
Fungal Infections ◽  
Virus Disease ◽  
Case Series ◽  
Health Crisis ◽  
Major Health ◽  
Corona Virus ◽  
Patients With Diabetes ◽  
Causative Agents

Corona virus Disease 2019 (COVID-19) pandemic is causing a major health crisis across the globe. With the increasing number of fungal infections associated with COVID-19 being reported, it is imperative to understand the spectrum of such infections. Most documented cases have been reported in patients with diabetes mellitus or treatment with immunomodulators. The most common causative agents are Aspergillus, Candida or Mucorales. This series aims to portray the spectrum of fungal infections associated with COVID-19.

scholarly journals Chloroquine-induced Prolonged QT Interval in COVID-19 Patients in Indonesia: Case Series

2021 ◽  
Vol 14 (1) ◽  
pp. 01-05
Author(s):  
Putu Dyah Widyaningsih ◽  
Putu Gita Pranata Putra ◽  
DG Wedha Asmara ◽  
Erna Bagiari ◽  
Agus Santosa ◽  
...  
Keyword(s):  
Qt Interval ◽  
Virus Disease ◽  
Case Series ◽  
Corona Virus ◽  
Prolonged Qt Interval ◽  
Prolonged Qt ◽  
Anti Inflammation

The treatment of corona virus disease 2019 (COVID-19)remains in debate, and the use of chloroquine has not been validated by accurate clinical trials.The aim of this study was to provide the possible cardiotoxicity effect of chloroquine in patients with COVID-19. This study was a case-series of prolonged QT interval of COVID-19 patients treated with chloroquine in a hospital in Bali, Indonesia. There were two cases of COVID-19 with exhibited a prolonged QT interval after being administrated of chloroquine. The prolonged QT interval returned to normal after chloroquine was stopped.These cases alert us the cardiotoxicity effect of chloroquine and the need for serial electro-cardiography monitoring before and during therapy. In conclusion, although antiviral and anti-inflammation properties of chloroquine on COVID-19 are promising, its cardiotoxicity effects should be monitored closely for less harm to the patients.

Outcomes of Steroid Therapy in Combination with Endoscopic Optic Nerve Decompression Surgery for Direct Traumatic Optic Neuropathy: A Case-Series

2021 ◽  
Vol 104 (7) ◽  
pp. 1166-1171
Keyword(s):  
Visual Acuity ◽  
Optic Nerve ◽  
Optic Neuropathy ◽  
Poor Prognosis ◽  
Combined Treatment ◽  
Treatment Protocol ◽  
Case Series ◽  
Light Perception ◽  
Traumatic Optic Neuropathy ◽  
Nerve Decompression

Background: Direct traumatic optic neuropathy (TON) carries a poor prognosis. However, the outcome of this injury is diverse and is related to time to treatment and treatment protocol. Objective: To evaluate the outcomes of the combined treatment protocol in patients with direct TON. Materials and Methods: The authors retrospectively reviewed the medical records of patients between January 2015 and August 2019. Main outcome was visual acuity (VA) improvement after the treatment. Results: Thirteen patients (15 eyes) were included. The mean age was 38.61 years with a range of 13 to 65 years. Initial VA varied from no light perception (NPL) in seven eyes of six patients, light perception (PL) in one eye, counting fingers in two eyes, 20/200 in three eyes, and 20/60 in two eyes. Average timing to treatment was 2.8 days (range 0 to 7 days). There were no side effects of high-dose corticosteroids treatment in all patients. During a follow-up period of three months, six of 13 patients (46.1%) had VA improvement. Conclusion: Despite poor prognosis of direct TON, the combined treatment protocol provides a favorable successful rate with most patients on having stable vision, and some having visual improvement from reducing intracanalicular pressure of the optic nerve. Keywords: Endoscopic optic nerve decompression; Traumatic optic neuropathy; Visual acuity; Case series

scholarly journals EVALUASI KESEHATAN KERJA PETUGAS KESEHATAN DI IGD RSUD PALEMBANG BARI TERHADAP WABAH COVID-19

2021 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Riska Nia Andriani ◽  
Gunawan A. Tohir ◽  
Vina Pramayastri
Keyword(s):  
Virus Disease ◽  
Case Series ◽  
Rt Pcr ◽  
Corona Virus

COVID-19 (Corona Virus Disease 2019) merupakan penyakit akibat infeksi SARS-CoV-2. Tenaga kesehatan merupakan kelompok yang paling rentan terpapar virus ini dikarenakan adanya kontak langsung dengan orang yang terinfeksi. Penelitian ini bertujuan untuk mengevaluasi kesehatan kerja petugas kesehatan di IGD RSUD Palembang BARI terhadap wabah COVID-19. Metode penelitian ini adalah penelitian kuantitatif dengan desain deskriptif case series. Hasil penelitian ini menunjukkan bahwa yang paling banyak ditemukan adalah karakteristik petugas kesehatan dengan usia antara 26–35 tahun, masa kerja >3 tahun dan lama kerja >8 jam, patuh menggunakan APD yang sesuai dengan rekomendasi WHO atau Kemenkes RI, jam kerja tetap, pendapatan yang tidak bertambah atau tetap, RT-PCR negatif, adanya rasa takut dan melakukan tindakan pencegahan terhadap COVID-19, serta motivasi kerja yang tidak rendah. Sehingga dapat disimpulkan bahwa petugas kesehatan di IGD RSUD Palembang BARI patuh menggunakan APD yang sesuai dengan rekomendasi WHO atau Kemenkes RI serta motivasi kerja yang tidak rendah. Saran bagi tenaga kesehatan diharapkan dapat terus mempertahankan kepatuhan dalam menggunakan APD, motivasi kerja maupun tindakan pencegahan.

Severe COVID-19 infection in a 32 weeks pregnant woman successfully treated with convalescent plasma therapy

2021 ◽  
pp. 64-66
Author(s):  
Ashraful Hoque ◽  
Talukder Mohammad Al Amin
Keyword(s):  
Pregnant Woman ◽  
Pregnant Women ◽  
Private Hospital ◽  
Virus Disease ◽  
Case Series ◽  
Favourable Outcome ◽  
Plasma Therapy ◽  
Corona Virus ◽  
Women Experiences

From the beginning of corona virus disease 19(COVID-19) pandemic, there has been concern how to protect vulnerable group like pregnant women from severe acute respiratory syndrome corona virus 2(SARS-CoV-2). Historically, pregnant women experiences increased mortality during any pandemic situation. Pregnant women show almost the similar clinical features as that of non-pregnant adults with COVID-19 infection. Different systematic reviews have begun to focus light on pregnancy outcomes in COVID-19 patients, but knowledge is very limited and still the basis is case series and individual experiences. Apart from the scientifically proven therapeutic options used in COVID-19 such as steroid, low molecular weight heparin, the role of convalescent plasma therapy (CPT) has never been evaluated. We present a case of a pregnant woman of 32 weeks of conception, treated with CPT with favourable outcome in a private hospital of Dhaka, Bangladesh. BSMMU J 2021; 14 (COVID -19 Supplement): 64-66

scholarly journals Endoscopic Trans-ethmo-sphenoidal Optic Nerve Decompression for Traumatic Optic Neuropathy: Case Series and Review

2015 ◽  
Vol 8 (3) ◽  
pp. 99-103
Author(s):  
Manish Gupta ◽  
Gavinder Singh Bindra ◽  
Ravi Vohra
Keyword(s):  
Optic Nerve ◽  
Optic Neuropathy ◽  
Case Series ◽  
Visual Outcome ◽  
Traumatic Optic Neuropathy ◽  
Nasal Endoscope ◽  
Endoscopic Endonasal ◽  
Tertiary Referral Center ◽  
Nerve Decompression ◽  
Optic Nerve Decompression

ABSTRACT Objective To assess the visual outcome after endoscopic, endonasal trans-ethmo-sphenoidal optic nerve decompression in patients with traumatic optic neuropathy. Materials and methods Prospective study, at tertiary referral center. Study included 12 patients with post-traumatic indirect unilateral optic nerve injury, not responding to medical management with methylprednisolone. These patients underwent optic nerve decompression via trans-ethmo-sphenoidal route using nasal endoscope. Main outcome measure was postoperative visual acuity. Results Out of the 12 cases of traumatic optic neuropathy (TON) operated upon, nine had good visual outcome. Conclusion The endoscopic endonasal trans-sphenoidal approach can decompress the traumatized and swollen optic nerve with excellent visualization of the orbital apex and optic canal, without the morbidity associated with brain retraction as in the conventional transcranial decompression. How to cite this article Gupta M, Bindra GS, Vohra R. Endoscopic Trans-ethmo-sphenoidal Optic Nerve Decompression for Traumatic Optic Neuropathy: Case Series and Review. Clin Rhinol An Int J 2015;8(3):99-103.

scholarly journals Therapeutic Management of Covid-19 Pneumonia with Ayurveda – Case Series Report

2021 ◽  
Vol 5 (2) ◽  
pp. 113-121
Author(s):  
Ghanshyam M Dongare ◽  
Yashashree V. Joshi
Keyword(s):  
Virus Disease ◽  
Case Series ◽  
Evidence Based ◽  
X Rays ◽  
Antigen Test ◽  
Rt Pcr ◽  
Corona Virus ◽  
Case Series Report ◽  
Ayurvedic Treatment ◽  
Series Report

Infection of Severe Acute Respiratory Syndrome Corona virus 2 (SARS-CoV- 2) which causes novel corona virus disease (COVID-19) has put the world in a medical disaster. Scientists are taking vast efforts to contain the disease by finding a vaccine or clinically proven medicine. Despite the efforts there is no proven medication in any stream of medicine. Covid19 affects respiratory tract and causes pneumonia. Here we are presenting a case series report of patients who had developed Covid19 with subsequent pneumonia and approached for Ayurvedic treatment. All these patients were primarily diagnosed with Covid-19 by RT PCR and SAARS Covid-19 Antigen test. They had subsequently developed viral pneumonia. As per Ayurveda, patients had developed symptoms of vitiation of Vata and Kapha Doshas which affected Rasavaha Srotasa and Pranavaha Srotasa. Patients were treated uniformly with internal Ayurvedic medicines which were prescribed for median duration of 30days and had been analyzed clinically with pre and post chest X-rays. All the symptoms were relieved as well as haziness in chest was also cleared in all patients, which was confirmed with pre and post chest x-rays. This study will be an evidence-based example that Ayurveda can contribute in fight against Covid-19 successfully.

scholarly journals EFFICACY OF AYURVEDA THERAPEUTICS IN PREVENTION AND MANAGEMENT OF COVID 19 PANDEMIC AND POST COVID RECOVERY PHASE: AN EVIDENCE BASED REVIEW

2021 ◽  
Vol 12 (01) ◽  
Author(s):  
Dr Archana Rai
Keyword(s):  
Virus Disease ◽  
Recovery Phase ◽  
Evidence Based ◽  
Disease Manifestation ◽  
Targeting Therapy ◽  
Corona Virus ◽  
Therapeutic Measures ◽  
Dreaded Disease ◽  
Work Done ◽  
The Impact

Corona virus disease 19 (COVID 19) is a dreaded disease caused by Severe Acute Respiratory Syndrome corona virus 2(SARS CO V2). This wide spread pandemic had taken whole world into custody, alone in India as per data available on myGov (Govt of India website) more than 3 cr. people affected and 4 lac surplus fatalities reported till 17 September 2021. Post COVID complications are also severe and hospitalisation is needed in some cases. Despite all the prophylactic and therapeutic measures been taken to contain the disorder, strategies to cure it thoroughly without other complications, is still a challenge. Though vaccination drive against COVID 19 is running successfully in India, medicines to minimise the impact and sufferings because of COVID is indispensable. Approaching holistically based on Dosha sidhanta Ayurveda therapeutics had shown favourable results in COVID positive patients. Ayurveda believes that disease manifestation is the result of imbalanced doshas, if we become competent to manage and pacify those doshas, disease can be cured. Vyadhipratyanik chikitsha (disease and symptoms targeting therapy) and Hetupratyanik chikitsha (cause and dosha targeting therapy) are the modules that are approached in Ayurveda system. Reviewing the previous work done in this field and observing COVID19 on Ayurveda parameters, Ayurveda medicines and therapeutics have been anticipated here to heal the scar impacted by precarious COVID 19. Much more researches and clinical interventions are required to establish kind of effective therapy.

scholarly journals Co-existence of multisystem inflammatory syndrome in children associated with COVID-19 and scrub typhus infection: a case series

2021 ◽  
Author(s):  
Sarbani M. Roy ◽  
Sushama Sahoo
Keyword(s):  
Clinical Features ◽  
Scrub Typhus ◽  
Virus Disease ◽  
Clinical Manifestations ◽  
Case Series ◽  
World Health ◽  
Laboratory Findings ◽  
Term Outcome ◽  
Corona Virus ◽  
Inflammatory Syndrome

We are in the midst of pandemic of corona virus disease (COVID-19), caused by the novel coronavirus severe acute respiratory syndrome corona virus-2 (SARS-CoV-2). A clinical entity with hyperinflammatory syndrome, defined by World Health Organization (WHO) as multisystem inflammatory syndrome in children (MIS-C) and adolescents, temporarily related to COVID-19, is being reported in this pandemic from several countries. MIS-C has overlapping clinical features of Kawasaki disease (KD). KD has been described in association with various organisms including dengue, scrub typhus. MIS-C with concomitant infection has rarely been reported in literature till date. We report on ten sick pediatric patients presented with clinical features of MIS-C, in whom diagnosis of concomitant scrub typhus were also made. This retrospective study was conducted in the department of pediatric medicine of a medical college, in a district town of West Bengal, India. SARS-CoV-2 immunoglobulin G level was elevated in all of them and they were also positive with Scrub typhus serology. We reviewed and analysed their basic informations, clinical manifestations, epidemiological history, laboratory findings, treatment and short term outcome. Median age was 24 months (range 4 months-8 years), male: female was 1:1. All the patients survived. Concomitant tropical infection in a patient with MIS-C may play an important role in determining the prognosis of such patients. Early detection and intervention will result in better management and intact survival of them.

scholarly journals Corona Virus Disease 2019 in situ arterial and venous thrombosis in critically ill patients: a case series

2020 ◽  
Author(s):  
Mireya Castro-Verdes ◽  
Antonia Gkouma ◽  
John Wort ◽  
Carole Ridge ◽  
Saeed Mirsadraee ◽  
...  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Virus Disease ◽  
Case Series ◽  
Bleeding Risk ◽  
Conventional Mechanical Ventilation ◽  
Cross Sectional ◽  
Cardiorespiratory Failure ◽  
Corona Virus

Abstract Background Corona Virus Disease 2019 (COVID-19) pneumonitis associated with severe respiratory failure carries a high mortality. Coagulopathy has emerged as a significant contributor to thrombotic complications. Case summary We describe two cases of severe COVID-19 pneumonitis refractory to conventional mechanical ventilation and proning position, transferred to our specialist centre for cardiorespiratory failure. Cross-sectional imaging demonstrated concurrent venous and aortic thrombosis with end-organ ischaemic changes. One patient received thrombolysis with a partial response. This could not be offered to the other patient due to a recent haemorrhagic event. Both patients died of multi-organ failure in the hospital. Discussion Concurrent aortic and venous thromboses are rare. This finding in COVID-19 cases, who were both critically ill patients, likely reflects the strongly thrombogenic nature of this illness which ultimately contributed to poor outcomes. The absence of deep vein thrombosis or a potential systemic source of embolism suggests in situ thrombosis. Further, the management of anticoagulation and thrombolysis is challenging in patients where an attendant bleeding risk exists.

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