scholarly journals Antibiotic Sensitivity Pattern in Neck Space infection

2020 ◽  
Vol 19 (2) ◽  
pp. 28-31
Author(s):  
Md Mukhlesur Rahman ◽  
Mahmuda Begum ◽  
Md Mujibul Hoque Khan ◽  
Mostafa Mahfuzul Anwar
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Agents ◽  
Antibiotic Sensitivity ◽  
Neck Surgery ◽  
College Hospital ◽  
Klebsiella Species ◽  
Medical College ◽  
Space Infection ◽  
Sensitivity Pattern ◽  
Life Threatening

Background: Infection caused by microorganisms are common and may be serious and life threatening, requires immediate attention and management to get best outcome. The purpose of this study is to assess the anatomical spaces and causative microorganisms responsible for neck infections and evaluate the sensitivity pattern of the isolated microorganisms to antimicrobial agents. Materials and methods: This study was carried out in the Department of Otolaryngology- Head and Neck Surgery, Chittagong Medical College Hospital, from January to December 2018. A total of 70 cases were selected consecutively. All underwent surgical incision & drainage. Pus sample was obtained either by aspiration or by swab stick from the involved spaces and culture and sensitivity tests were performed. Results: The most common neck space infection were submandibular abscess 27 (38.57%) followed by Ludwig's angina 20 (28.57%). Out of 70 cases, 51(72.86%) cases yielded positive growth and 19(27.14%) cases showed no growth. Predominant microorganisms were Staphylococcus aureus, Streptococcuspyogenes, klebsiellaspecies and E coli. Staphylococcus aureus showed sensitivity to vancomycin, clindamycin, gentamycin. Streptococcus pyogenes showed sensitivity to cefuroxime, ceftriaxone and klebsiella species showed sensitivity to amikacin. Conclusion: Bacteriological examination and culture help to identify the causative microorganisms in neck abscess. It helps to isolate even the rarest of the organism and by knowing there sensitivity pattern, we can direct specific therapy against them. It thus helps in a more effective treatment and fast recovery of patients. Chatt Maa Shi Hosp Med Coll J; Vol.19 (2); July 2020; Page 28-31

scholarly journals Bacteriological profile of pyoderma in a tertiary care centre in Kerala, India

2016 ◽  
Vol 2 (1) ◽  
pp. 1
Author(s):  
Soumya Rani R ◽  
Jayalekha B ◽  
Sreekumary P. K.
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Agents ◽  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Bacterial Agent ◽  
Bacteriological Profile ◽  
Sensitivity Pattern ◽  
One Year

<p><strong>Background: </strong>Pyoderma is a leading cause of childhood infection, which also affects the adults with a changing trend of antibiotic sensitivity pattern of the bacterial agent. A study on the bacteriological profile of pyoderma and its antibiotic sensitivity pattern is beneficial as it is the first study of its kind in this study centre.<strong> </strong>The main objective of the study was to find the bacteriological profile and the antibiotic sensitivity pattern of the isolates.<strong></strong></p><p><strong>Methods: </strong>A descriptive study was conducted during a one year period at Government medical college, Kottayam, India. 150 cases were studied. Data was collected to assess the risk factors. Pus collected from the site of infection was cultured, the organisms were identified and their antibiotic sensitivity pattern was found by conventional methods. <strong></strong></p><p><strong>Results: </strong>There were 173 isolates obtained from 150 patients. The predominant isolate obtained was <em>Staphylococcus aureus </em>including 13% of MRSA, followed by <em>Beta hemolytic Streptococci</em>. Other isolates obtained were <em>Pseudomonas aeruginosa</em> and <em>Citrobacter amalonaticus</em>.<strong></strong></p><strong>Conclusion: </strong>The most common organism causing pyoderma is found to be <em>Staphylococcus aureus </em>which include 13.3% of MRSA. The next common isolate obtained is<em> Beta hemolytic Streptococci. </em>38 cases showed mixed infections including few gram negative bacilli. So this study emphasizes the need for pus culture and sensitivity which facilitates the appropriate usage of antimicrobial agents which can prevent emergence of antimicrobial resistance.

Antibiotic Sensitivity and Resistance Patterns of Salmonella Typhi in Rajshahi Medical College Hospital

2020 ◽  
Vol 33 (2) ◽  
pp. 10-14
Author(s):  
Md Azizul Haque ◽  
Laila Shamima Sharmin ◽  
KM Faisal Alam ◽  
Md Mohimanul Hoque ◽  
M Morsed Zaman Miah ◽  
...  
Keyword(s):  
Blood Culture ◽  
Enteric Fever ◽  
Antibiotic Sensitivity ◽  
Salmonella Typhi ◽  
Medical College Hospital ◽  
Personal Hygiene ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College ◽  
Sensitivity Pattern

Typhoid and paratyphoid fevers, collectively known as enteric fever, is caused by Salmonella enterica subspecies serovars Typhi and Paratyphi A, B and C. Despite this declining global trend, enteric fever is still considered to be a major public health hazard in Bangladesh and other developing countries due to poor sanitation, inadequate food safety measures and poor personal hygiene. In Bangladesh, the incidence of typhoid fever was reported to be 200 episodes per 100,000 person-years during 2003–2004. Multidrug-resistant (resistance to the first-line antimicrobials ampicillin, cotrimoxazole, and chloramphenicol) strains of S. Typhi and S. Paratyphi are on the rise globally and even cases of extensively drug-resistant (XDR) typhoid cases resistant to chloramphenicol, ampicillin, trimethoprim-sulfamethoxazole, third generation cephalosporins and fluoroquinolones are being reported from many corners of the world. This descriptive, observational study was carried out in Rajshahi Medical College Hospital Hospital, Rajshahi, Bangladesh from July 2017 to June 2019. Antibiotic sensitivity pattern of total 76 cases of enteric fever due to Salmonella Typhi were studied. Blood culture was carried out by BACT ALERT-3D, Automated blood culture analyzer from BioMeriuex SA, France Patented FAN Plus method. Based on the minimum inhibitory concentration (MIC), the organism was categorized as sensitive, intermediate, and resistant against the respective antibiotics as per Clinical and Laboratory Standards Institute (CLSI) criteria. We are reporting antibiotic sensitivity and resistant patterns of S. Typhi documented in Rajshahi Medical College Hospital, a large tertiary care hospital in Northern Bangladesh. TAJ 2020; 33(2): 10-14

scholarly journals Blood Culture Isolates and Antibiogram of Salmonella: The Gathering Storm

KYAMC Journal ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 188-190
Author(s):  
Ishrat Binte Reza ◽  
HAM Nazmul Ahasan ◽  
Moshtaque Ahmed ◽  
Homayra Tahseen ◽  
Tasmina Chowdhury
Keyword(s):  
Drug Resistance ◽  
Antibiotic Sensitivity ◽  
Multidrug Resistant ◽  
Bacterial Strains ◽  
College Hospital ◽  
Major Health ◽  
Medical College ◽  
Sensitivity Pattern ◽  
Highly Sensitive ◽  
The World

Introduction: Typhoid fever is a common problem all over the world including Bangladesh. It is caused by salmonella typhae and paratyphae and it is an old infectious water born disease. It is encountered in Bangladesh throughout the year. For many years it is treated by Chloramphenicol and subsequently Cotrimoxazole and Amoxicillin. Despite the use of newly developed antibacterial drugs, enteric fevers caused by multidrug-resistant bacterial strains are one of major health problems in Bangladesh. Multidrug resistant Salmonella sp. has been emerged is a cause of concern. Materials and Methods: This is a retrospective study done at the Popular Medical College Hospital over a period of 6 months between January 2018 to june 2018. Results: During the study period, total 115 cases were enrolled. Regarding antibiotic sensitivity pattern, 69% strains were sensitive to Ampicillin, 100% to Cefixime and Ceftriaxone, 75% to Cotrimoxazole, 52% to Nalidixic Acid and 68% to Ciprofloxacin, 69% to Levofloxacin, 80% to Cholarphenicol. Conclusion: Ceftriaxone and Cefixime were found to be highly sensitive. So, we should be very careful for the judicious use of these valuable drug to prevent drug resistance. KYAMC Journal Vol. 10, No.-4, January 2020, Page 188-190

scholarly journals Prevalent Bacteria and Their Sensitivity and Resistance Pattern to Antibiotics: A Study in Dhaka Medical College Hospital

2017 ◽  
Vol 26 (1) ◽  
pp. 52-64
Author(s):  
Mohammad Zaid Hossain ◽  
Akhtarun Naher ◽  
Pratyay Hasan ◽  
Kazi Tuba E Mozazfia ◽  
Homyra Tasnim ◽  
...  
Keyword(s):  
Nalidixic Acid ◽  
Antibiotic Sensitivity ◽  
Sampling Technique ◽  
Salmonella Typhi ◽  
Medical College Hospital ◽  
Resistance Pattern ◽  
College Hospital ◽  
Medical College ◽  
Sensitivity Pattern ◽  
Changes Over Time

Background and rationale: Antibiotic resistance is a global problem. Many factors are complexly related to the issue in multiple dimensions. Bangladesh is right in the middle of this great calamity, and is seeing the rise in resistant strains of several bacteria. Very sadly, the prevalent malpractice of abusing antibiotics in Bangladesh contributes to add complexity to the danger which may prove to be possibly the greatest threat humans have ever faced. There is much scarcity of medical literature in Bangladesh, on the antibiotic sensitivity pattern and prevalent microorganisms. Moreover, antibiotic sensitivity pattern changes over time and place. Again, most of the studies done in Bangladesh, concentrate on a single disease, pathogen, or specimen. This study attempts to see the prevalent microorganisms and the antibiotic sensitivity pattern in multiple types of specimens collected from Dhaka Medical College Hospital. This study also attempts to establish a way of presentation of the relevant findings which can be used in future to ensure easy comparability and contrasting of findings.Methods: The specimens were collected from the adult patients (age >12 years) admitted in the Internal Medicine ward of Dhaka Medical College Hospital, Dhaka, over a period of 6 months. The sampling technique was consecutive sampling method. Specimens which were culture positive, were only included in the study for analysis. Multiple specimens were taken.Results: S. aureus was 100% sensitive to amikacin, moxifloxacin, imipenem, meropenem, piperacillin+tazobactum combination, vancomycin, doxycycline, tetracycline, tigecycline, nitrofurantoin, azactum, linezolid and 100% resistant to cefixime. Enterobacter was 100% sensitive to penicillin, amikacin, gentamicin, netilmicin, doxycycline, tetracycline, tigecycline and 100% resistant to cefixime, ceftazidime, ceftriaxone, cefepime, cotrimoxazole, levofloxacin, vancomycin. E. coli was 100% sensitive to imipenem, meropenem, vancomycin, tigecycline and 100% resistant to mecillinam, aztreonam. Klebsiella was 100% sensitive to flucloxacillin, colistin, vancomycin, tigecycline, linezolid and 100% resistant to nalidixic acid. Proteus was 100% sensitive to cephradine, cefoxitin, cefixime, ceftazidime, ceftriaxone, cefepime, cotrimoxazole, amikacin, ciprofloxacin, imipenem, meropenem, netilmicin, piperacillin+tazobactum combination, tetracycline, tigecycline, azithromycin, azactum and 100% resistant to doxycycline, tetracycline, chloramphenicol and cefuroxime. Pseudomonas was 100% sensitive only to amikacin, netilmicin, and 100% resistant to cefixime, ceftazidime, ceftriaxone, cefepime, cotrimoxazole, gentamicin, ciprofloxacin, levofloxacin, imipenem, meropenem, doxycline, tetracycline, chloramphenicol. Salmonella typhi was 100% sensitive to amoxicillin, cefoxitin, cefixime, ceftriaxone, cefepime, cotrimoxazole, amikacin, netilmicin, azithromycin, chloramphenicol, azactum and 100% resistant to cephradine, doxycycline, tetracycline, nalidixic acid. MRSA was 100% sensitive to imipenem, vancomycin, teicoplanin, nitrofurantoin, linezolid and 100% resistant to cefpirome, cefoxitin, ceftazidime, cotrimoxazole, clindamycin, gentamicin, ciprofloxacin, netilmicin, tetracycline, clarithromycin. Acinetobacter was 100% sensitive to penicillin, cefuroxime, colistin, piperacillin+tazobactum combination, tigecycline, chloramphenicol and 100% resistant to cefixime, nalidixic acid. Citrobacter freundii was 100% sensitive to ceftazidime, ceftriaxone, cotrimoxazole, amikacin, gentamicin, ciprofloxacin, levofloxacin, imipenem, meropenem, netilmicin, nalidixic acid and 100% resistant to ampicillin, cefixime, nitrofurantoin.Conclusion: More and more antibiotics are becoming ineffective due to emergence of resistance. Serious actions should be taken. Awareness should be raised from the policy maker level to the physicians and patients.J Dhaka Medical College, Vol. 26, No.1, April, 2017, Page 52-64

scholarly journals Screening of Milk Borne Staphylococcus aureus for Resistance against Beta Lactam Antibiotics

2020 ◽  
Author(s):  
B. Anurag ◽  
T. Ramasamy ◽  
S. Ramesh ◽  
K.S. Sriraam ◽  
L. Kalaiselvi ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Meca Gene ◽  
Antibiotic Sensitivity ◽  
Large Animal ◽  
Beta Lactam ◽  
College Hospital ◽  
Mannitol Salt Agar ◽  
Beta Lactam Antibiotics ◽  
Outpatient Unit ◽  
Sensitivity Pattern

Background: A study was carried out to screen milk borne Staphylococcus aureus for resistance against Beta lactam antibiotics. Methods: A total of 45 milk samples were collected over a period of three months from large animal outpatient unit of Madras Veterinary College Hospital, Chennai. Upon collection of samples, ABST followed by its growth in Mannitol Salt Agar was carried out as part of the phenotypic screening. Genotypic screening for Staphylococcus screening was done with the help of PCR by using nuc and mec A primers. MIC for ceftriaxone and cloxacillin was carried out with the samples that were found positive for Staphylococcus aureus. The antibiotic sensitivity pattern is presented: Fluoroquinolones (87.5% sensitive), aminoglycosides (72.5% sensitive), Amoxicillin-Clavulanic acid (Amoxyclave) (72.5% sensitive). The MSA positive samples were subjected to molecular identification with the help of PCR. Result: The results revealed 10 samples positive for Staphylococcus aureus and 5 among them positive for mecA gene. The MIC results were as follows: MIC50-10.95µg/ml and MIC90- 87.510.95µg/ml for ceftriaxone and MIC50- 43.75 µg/ml and MIC90- 87.5µg/ml for cloxacillin, indicating emergence of resistance. However, further studies are required in a larger sample size that can help us to attain more conclusive results.

scholarly journals Antibacterial susceptible pattern of ear, nose and throat in paediatric patient infections

2017 ◽  
Vol 6 (8) ◽  
pp. 1900
Author(s):  
Selvaraj Rajendran ◽  
Chakrapani Cheekavolu ◽  
Rama Mohan Pathapati ◽  
Madhavulu Buchineni
Keyword(s):  
Staphylococcus Aureus ◽  
College Hospital ◽  
Antibiotic Susceptibility Pattern ◽  
Medical College ◽  
Gram Positive Bacteria ◽  
Sensitivity Pattern ◽  
Antimicrobial Susceptibility Profile ◽  
Positive Growth ◽  
Klebsiella Spp ◽  
Nose And Throat

Background: To study the bacterial pathogens of ear, nose and throat (ENT) to determine the frequency and sensitivity pattern of ENT infections in paediatric patients.Methods: The study was conducted during the period of June 2016 to May 2017 in Kerala Medical College Hospital. A total 225 samples were collected and evaluated for microbiological investigations. Antimicrobial susceptibility profile was determined by modified Kirby Bauer disc diffusion method.Results: Out of 225 samples, 140 (62.22%) were found positive growth and 85 (37.77%) of samples were found negative culture. The frequency of different organisms isolated was as follows: Pseudomonas 43 (30.71%), Staphylococcus aureus 32 (22.85%), Proteus spp. 18 (12.85%) Klebsiella spp. 17 (12.14%) etc., Antibiotic susceptibility pattern gram positive bacteria were vancomycin (100%) followed by amikacin (97.14%), and in gram negative bacteria; sulbactam/ cefoperazone (97.14%), piperacillin/tazobactam (95.23%) and meropenem (94.28%) were the most effective drugs.Conclusions: Pseudomonas aeruginosa, Staphylococcus aureus, Proteus spp. and Klebsiella spp. are the leading ENT pathogens in paediatric patients. Most of the isolates showed high resistance to cephalosporins. Showed high effectiveness to sulbactam/ cefoperazone, piperacillin/tazobactam.

scholarly journals STUDY OF BACTERIA ISOLATED FROM URINARY TRA INFECTION AND THEIR SENSITIVITY PATTERN

2004 ◽  
Vol 43 (154) ◽  
Author(s):  
Aarati Karki ◽  
B R Tiwari ◽  
S B Pradhan
Keyword(s):  
Staphylococcus Aureus ◽  
Retrospective Study ◽  
Nalidixic Acid ◽  
Urine Sample ◽  
Bacterial Species ◽  
Antibiotic Sensitivity ◽  
Klebsiella Species ◽  
E Coli ◽  
Sensitivity Pattern ◽  
Proteus Species

A retrospective study was conducted among out-patient and in-patient in Kathmandu medical collegeTeaching hospital of one month from the duration 2060-11-15 to 2060-12 -15. Mid-stream urine [MSU] of300 patient were cultured. Out of these, 75 patients’ urine were found to have significant bacterial growth.Total of five species of bacterial species isolated were viz.E.coli 37(33.3%), Proteus species 25(27.7%),Klebsiella species 15(16.6%), Staphylococcus aureus 8(8.8%) and Pseudomonas aureginosa 1(1.1%).Regarding their antibiotic sensitivity pattern, E. coli were sensitive to Nitrofurantoin 31 (83.8% ), Norfloxacin25 (67.5%), Ofloxacin 30(81.0%), Amoxycillin 16(43.2%), Nalidixic acid 15 (40.5%).proteus species weresensitive to Nitrofurantoin 15 (60.0%), Norfloxacin 15 (60.0%), Ofloxacin 12(48.0%), Amoxycillin 13(52.0%),Nalidixic acid 10 (40.0%), Ciprofloxacillin 12(48.0%). Klebsiella species were sensitive to Nitrofurantoin 9(60.0%), Norfloxacin 5 (33.3%), Oflaxin 6(40.0%), Amoxycillin 5(33.3%), Nalidixic acid 4 (26.6%),ciprofloxacillin 6(40.0%).Staphylloccus aureus were sensitive to Nitrofurantoin 8(100.0%), Norfloxacin 6(75.0%), Oflaxin 8(100.0%),Amoxycillin 7(87.5%), Nalidixic acid 6(75.0%), Ciprofloxacillin 8(100 %). And Pseudomonas aureginosawere resistant to all antibiotics which we are using in this research work.Key Words: Urine sample, Identification, Sensitivity pattern.

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