scholarly journals Pattern of Common Inherited Coagulation Disorders: Evaluation of 100 Cases

2020 ◽  
Vol 15 (1) ◽  
pp. 64-66
Author(s):  
Mohammed Nuruzzaman Bhuiyan ◽  
Maj Gen Susane Giti ◽  
Mohammed Mosleh Uddin ◽  
Monwar Tarek ◽  
Lutfunnahar Khan
Keyword(s):  
Clinical Manifestations ◽  
Cost Effective ◽  
Armed Forces ◽  
Fresh Frozen Plasma ◽  
Haemophilia A ◽  
Age Group ◽  
Coagulation Disorders ◽  
Cross Sectional ◽  
Female Ratio ◽  
Coagulation Defect

Introduction: The bleeding disorders having inherited abnormality of haemostasis may present with significant difficulties in diagnosis and management. The overall frequency of these disorders in the general population is low. Objectives: To study the frequency of inherited coagulation disorders and their prevalent clinical manifestations. Materials and Methods: A prospective cross sectional study of one hundred patients of all age group and both sexes was organized as both in-patient and out-patient based in the Department of haematology, Armed Forces Institute of Pathology (AFIP) from July 2012 to June 2013. Results: In this study, out of 100 patients, haemophilia A, diagnosed in 75% patients, was the most common disorder. Age group ranging from 5-15 years constituted 48% of total patients. Male to female ratio of patients having hereditary coagulation defect was 73:2 in haemophilia A whereas 2:3 in vWD. Consanguinity was documented in 60% of vWD and 24% of haemophilia A. The most common clinical symptom in hereditary coagulation defect (HCD) was echymosis (60%). The most common presenting feature of haemophilia was haematoma (57.95%) whereas menorrhagia was the most common presentation of female patients with vWD. Among 97 patients of haemophilia and vWD, 59(60.82%) cases were in mild form and 04(4.12%) cases were found to have severe coagulation defect. Fresh frozen plasma (FFP) is the most common modality of treatment in HCD. Conclusion: It has become the need of the time to find out such a cost effective diagnostic parameter to make an early diagnosis of inherited coagulation disorders. Journal of Armed Forces Medical College Bangladesh Vol.15 (1) 2019: 64-66

scholarly journals Role of Squash Cytology in Intraoperative Diagnosis of Meningioma

2021 ◽  
Author(s):  
Gowri Prakasam ◽  
K Karkuzhali ◽  
Veeraraghavan Gurusamy
Keyword(s):  
Tamil Nadu ◽  
Frozen Section ◽  
Cost Effective ◽  
Cross Sectional Study ◽  
Histopathological Diagnosis ◽  
Suspected Case ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Cost Effective Technique

Introduction: Primary Central Nervous System (CNS) tumours constitute less than 2% of overall cancers in adults and are the second most frequently encountered tumours in children. Meningiomas form 24-30% of primary intracranial tumours. Most intrinsic brain tumours are soft and gelatinous in consistency, smear preparation can readily made which gives excellent cytological details when compared to frozen section as the latter produces ice crystal artifacts. Aim: To assess the diagnostic utility of squash cytological evaluation of meningiomas and its comparison with final histopathological diagnosis. Materials and Methods: The cross-sectional study was done at Thanjavur Medical College, Thanjavur, Tamil Nadu, India for period of three years from January 2015 to December 2017. Total of 54 clinically diagnosed and radiologically suspected case of meningiomas were selected. Smears were prepared from the biopsy samples sent in normal saline and stained by Haematoxylin and Eosin (H&E) method. The cytological features were noted and matched with biopsy findings. Descriptive statistics were used to analyse the results. Results: Total of 54 squash smears with male to female ratio was 1:1.5. Maximum number of cases were seen between 41- 50 years followed by 51-60 years. Complete concordance was obtained in 51 cases (94.44%) and partial concordance was noted in a case due to underestimation of malignancy grade in squash cytology. Out of 54 cases, two cases were found to be discordant with final histopathological diagnosis. Conclusion: Intraoperative squash cytology is easy, rapid, reliable and cost-effective technique for neurosurgical consultation with fairly high accuracy in diagnosing meningiomas.

scholarly journals Prevalence of Metabolic Syndrome among Border Guard Bangladesh Personnel

2020 ◽  
Vol 14 (2) ◽  
pp. 97-100
Author(s):  
Md Abdul Wahab ◽  
Md Mustafizur Rahman ◽  
Md Abdur Razzak ◽  
Md Habibur Rahman ◽  
Mimi Parvin ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
International Diabetes Federation ◽  
Armed Forces ◽  
Cross Sectional Study ◽  
Age Group ◽  
Metabolic Abnormalities ◽  
Sectional Study ◽  
Ethnic Population ◽  
Cross Sectional ◽  
Medical College

Introduction: Metabolic syndrome (MetS) is a multifaceted syndrome comprises a cluster of metabolic abnormalities including hypertension, central obesity, insulin resistance, dyslipidemia, and is strongly associated with developing diabetes mellitus and cardiovascular diseases. Prevalence of MetS differs in different ethnic population by using different definition. Objectives: To determine the prevalence of the MetS and its component risk factors among Border Guard Bangladesh (BGB) personnel working in Chattagram Hill Tract (CHT). Materials & Methods: This descriptive cross-sectional study was conducted from October 2016 to February 2018 among 1455 male BGB personnel aged between 40 to 59 years and working in CHT of Bangladesh. Study subjects were selected at BGB hospital, Guimara, Khagrachari. The new International Diabetes Federation (IDF) guidelines were used to identify MetS. Detail history, clinical examination, anthropometry and blood pressure (BP) were measured and fasting plasma glucose (FPG) and lipid profile were assessed. Results: Among the 1455 respondents’ BMI, waist circumference, systolic and diastolic BP were found more than normal in 34.1, 37.7, 16.4% and 12.3% respectively. Biochemical parameters including FPG, TC, TG, and LDL-C was raised in 28.7%, 49.8%, 52.2% and 37.7% of respondents respectively. HDL-C was found decreased in 26.9% respondents. Age wise prevalence of MetS for age group 40-44, 45-49, 50-54 and 55- 59 years were found 21.3%, 21.7%, 24.1% and 26.1% of the respondents respectively. The overall prevalence of MetS was found 22.4%. Conclusion: The prevalence of the MetS in BGB personnel was found 22.4%. Appropriate measure should be taken to lower the MetS cases. Journal of Armed Forces Medical College Bangladesh Vol.14 (2) 2018: 97-100

scholarly journals Study of psychiatric morbidity of patients attending free mental health check up camp, Simara, Bara district of Nepal

2013 ◽  
Vol 2 (1) ◽  
pp. 30-34
Author(s):  
CP Sedain
Keyword(s):  
Mental Health ◽  
Depressive Disorder ◽  
Demographic Data ◽  
Psychiatric Morbidity ◽  
Cross Sectional Study ◽  
Health Clinic ◽  
Age Group ◽  
Cross Sectional ◽  
Female Ratio ◽  
Community Mental Health Clinics

Introduction: Maryknoll Nepal has been running community mental health clinics different part of the country. The aim of the study was to find out psychiatric morbidity of patients attending Maryknoll free check up clinic Simara, Bara district of Nepal. Methods: A prospective cross-sectional study comprised of all consecutive patients attending Maryknoll free check up clinic Simara, Bara district, Nepal. All the patients attending the free clinics were taken as cases. The study was conducted in January 2009. Demographic data and disease profile of 87 patients attending the clinic were analyzed. The ratios and proportions were used for statistical analysis. Results: Data from Simara free mental health clinic shows that the male to female ratio was 0.55:0.44.The age group 30-39(N-25, 28.74%) followed by age group 20-29 (N-19, 21.84%) was the commonest. The farmer were (N-49, 56.31 %) the most common visitor. The highest number of cases were depressive disorder (N-16, 18.93 %) followed by mania/BPAD (N-14, 16.09 %) and Schizophrenia (N-12, 13.73 %). Conclusion: The commonest incidence of psychiatric illness attending the free clinic is depressive disorder and mania/BPAD. DOI: http://dx.doi.org/10.3126/jpan.v2i1.8572 J Psychiatrists’ Association of Nepal Vol .2, No.1, 2013 30-34

scholarly journals IN-HOSPITAL EARLY COMPLICATIONS IN DIABETICS VS NON DIABETICS WITH ACUTE ST ELEVATION MYOCARDIAL INFARCTION AGE GROUP 30-70 YEARS

2021 ◽  
Vol 70 (Suppl-4) ◽  
pp. S576-80
Author(s):  
Gul Khan ◽  
Imtiaz Ahmed Khan ◽  
Fahad Ahmad Khan ◽  
Shaheer Farhan ◽  
Javeria Kamran ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Armed Forces ◽  
Cross Sectional Study ◽  
Diabetic Group ◽  
Diabetic Patients ◽  
Age Group ◽  
Sectional Study ◽  
Early Complications ◽  
Cross Sectional ◽  
St Elevation

Objective: To determine in hospital early complications in diabetics’ vs non diabetics with acute ST elevation myocardial infarction. Study Design: Comparative cross-sectional study. Place and Duration of Study: The study was conducted in emergency departments and adult cardiology wards of Armed Forces Institute of Cardiology/National Institute of Heart Diseases, from Aug to Nov 2019. Methodology: A comparative cross sectional study was conducted on 380 patients (190 patients with diabetes and 190 patients without diabetes) who presented with acute ST-Elevation MI in age group 30 to 70 years to emergency department of Armed Forces Institute of Cardiology/National Institute of Heart Disease during specified period. Patients with rescue PCI and new onset of LBBB were also included. Patients with age group lesser than 30 years or greater than 70 years with STEMI were excluded. Sampled with consecutive non probability technique in patients was assessed with ECG, cardiac enzymes, transthoracic echocardiography, renal Doppler and RFTs. All patients were admitted in wards and were followed up during hospital stay. Patients were evaluated and their record of Primary PCI and thrombolysis was also noted. Data was entered and analyzed with SPSS-23. Results: A total of 380 patients with STEMI were included in this study consisting of 292 (76.8%) male and 88 (23.1%) female from 30 to 70 years. The patients were divided in two groups i.e. diabetic and non-diabetic, 190 patients were included in each group. It was found that frequency of ST-Elevation MI was higher in diabetic group as compared to non-diabetic group. All the patients were analyzed for complications occurred after STElevation MI. LV failure, Brady arrhythmias, atrial fibrillation, post MI angina and cardiogenic shock were the main complications noted. It was found that all these complications are more in diabetic group post MI angina which occurred most frequently in non-diabetic group. Conclusion: In our study we observed that left ventricular failure and arrhythmias were the major complications. Mortality was higher in diabetic patients than non-diabetic patients. In both groups PPCI and SK reduced mortality. Post MI angina were found more frequent in non-diabetic group.

CLINICAL STUDY OF POST COVID SYMPTOMS AFTER 1ST WAVE OF COVID 19, AT A TERTIARY HOSPITAL

2021 ◽  
pp. 51-53
Author(s):  
Dilip Pandurang Patil
Keyword(s):  
Chest Pain ◽  
Tertiary Hospital ◽  
Residual Effects ◽  
Chronic Obstructive ◽  
Age Group ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Female Ratio ◽  
Raising Awareness ◽  
Cognitive Disturbances

Background: Early reports suggest residual effects of SARS-CoV-2 infection, such as fatigue, dyspnea, chest pain, cognitive disturbances, arthralgia and decline in quality of life. In present study we aimed to evaluate post covid symptoms after 1st wave of COVID 19 in COVID 19 recovered patients at a tertiary hospital. Present study was Material and Methods: hospital based, descriptive, cross-sectional, questionnaire-based study conducted in Covid 19 positive patients (RT-PCR or Rapid Antigen positive patients) either hospital admitted or home isolation patients, recovered (either RTPCR negative or completed 14 days isolation and no symptoms) came to post covid OPD for follow up, were studied. In present study 101 post Results: COVID 19 recovered patients were studied. Most of patients were from age group 51-60 years (19.8 %) followed by age group 41-50 years (16.83 %). Male patients (65.35 %) were more than female patients (34.65%), male to female ratio was 1.9 :1. Majority of patients received treatment at hospital (75.25%) & were diagnosed by RTPCR (57.43%). Most of patients had recovered from COVID 61-90 days ago (28.71%) followed by 121-150 days ago (19.8%). During acute COVID-19 pneumonia was diagnosed in 36.63 % cases. Other characteristics were intensive care unit admission (14.85 %), oxygen supplementation (21.78 %), noninvasive ventilation (7.92 %) & mechanical ventilation (2.97 %). Pre-existing comorbidities noted were hypertension (12.87 %), thyroid disease (4.95 %), diabetes (3.96 %), chronic obstructive pulmonary disease (3.96 %), h/o kidney failure (1.98 %), active smoker (8.91 %) & former smoker (14.85 %). No regular physical activity was noted in 83.17 %. Post COVID symptoms noted in present study were cough (14.85 %), fatigue (13.86 %), Breathlessness (8.91 %), headaches (5.94 %), myalgia (3.96 %), palpitation (3.96 %), loss of smell sensation (3.96 %), muscle weakness (2.97 %), loss of taste sensation (2.97 %) & chest pain (1.98 %). Most of the Conclusion: COVID-19 survivors experienced mild post-recovery symptoms such as cough, fatigue, breathlessness, headache, myalgia & palpitation. Raising awareness, recognition, research, and multidisciplinary involvement will be considered the cornerstones to manage long-term sequelae of COVID-19 effectively.

scholarly journals Prevalence of Anti-Red Cell Antibodies in Repeatedly Transfused Patients

2019 ◽  
Vol 14 (1) ◽  
pp. 73-77
Author(s):  
Masuma Ahmed Salsabil ◽  
Ashesh Kumar Chowdhury ◽  
Debashish Saha ◽  
Arif Ahmed Khan ◽  
Sazia Sultana
Keyword(s):  
Haemolytic Anaemia ◽  
Armed Forces ◽  
Cross Sectional Study ◽  
Red Cell ◽  
Cross Sectional ◽  
Transfusion Therapy ◽  
Female Ratio ◽  
Medical College ◽  
Male Female Ratio ◽  
Immune Haemolytic Anaemia

Introduction: The development of anti-RBC antibodies (alloantibodies and/or autoantibodies) can significantly complicate transfusion therapy, particularly in patients needed repeated transfusion. Objectives: To find out the prevalence of alloantibodies and autoantibodies in repeatedly transfused patients so that serious hazards due to immune reaction may be avoided. Materials and Methods: This descriptive cross-sectional study was carried out in Department of Immunology, BIRDEM and Armed Forces Institute of Pathology (AFIP) during the period of July 2015 to June 2016. Total 370 patients who had received at least five units of transfusions were enrolled in this study but known patients of auto immune haemolytic anaemia, patients in whom antibody was previously detected and pregnant women were excluded from the study. Blood grouping and Direct Anti-globulin Test (DAT) were performed with cell suspension using a poly-specific Coombs reagent. In cases of a positive DAT, further investigation using specific monoclonal reagents to detect IgG or a complement (C3d) was carried out. Serum was used to detect red cell alloantibodies using standard blood bank methods. Antibody identification was performed in antibody screening positive samples using red cell Identicells. Results: Maximum 132 (35.7%) patients were in the age group 1-10 years. The male-female ratio was 1.2:1. Among 370 total patients 290 were HHA and 80 were non-HHA. Antibody was detected in only 17(4.59%) patients. Among the Hereditary Haemolytic Anaemia (HHA) patients it was 11 (3.79%) but among the non-HHA patients it was 6(7.5%). Out of 8 auto-antibodies, 5 were anti IgG followed by 3 were anti C3d. Out of 14 alloantibodies, 4(28.6%) were anti E, 3(21.4%) were anti K and in 3(21.4%) cases specificity of alloantibody was not detected. Conclusion: Prevalence of anti-RBC antibodies was not so uncommon in multiple transfused patients. Journal of Armed Forces Medical College Bangladesh Vol.14(1) 2018: 73-77

scholarly journals Assessment of immunization coverage and associated factors among children in Paravur Taluk of Ernakulam district, Kerala

2019 ◽  
Vol 6 (8) ◽  
pp. 3594
Author(s):  
Anuradha Kizhatil ◽  
Reshma . ◽  
Harsha Chollankil Hariharan ◽  
Alexander John ◽  
Ann Mary Thomas ◽  
...  
Keyword(s):  
Child Protection ◽  
Associated Factors ◽  
Immunization Coverage ◽  
Cost Effective ◽  
Cross Sectional Study ◽  
Bivariate Analysis ◽  
Cluster Sampling ◽  
Age Group ◽  
Cross Sectional ◽  
Group 5

Background: Immunization is one of the most cost-effective interventions averting countless childhood deaths and protecting millions of children from disability and illness. The objective of the current study was to assess the immunization coverage and associated factors among children aged 12-23 months and 5-7 years in Paravur Taluk of Ernakulam district, Kerala.Methods: A community based cross sectional study was done. Cluster sampling method of WHO was used for evaluation of immunization coverage.300 children in the age group of 12–23 months and 300 children in the age group 5-7 years were selected from each of the 30 clusters. Crude coverage details for each vaccine were estimated using percentages. Bivariate analysis was conducted to identify independent predictors of immunization coverage.Results: Among the children 12-23 months old, eleven (3.7%) children were partially immunized, while everybody had received at least one vaccine. The proportion of children fully immunized was 96.3%. Among the children 5-7 years old 55 (18.3%) were partially immunized. Belonging to Muslim religion, fathers’ occupation i.e. who were labourers/unskilled workers, mother’s education less than 12th standard and not possessing the mother and child protection card were found to be factors associated with partial immunization.Conclusions: This study shows that full immunization has not reached all children.

scholarly journals COVID-19 Cluster in School: A Study on Epidemiology and Clinical Manifestations among Cases from Rengas Cluster in Perak, Malaysia

2021 ◽  
Vol 2 (2) ◽  
pp. 125-134
Author(s):  
Syahrizal Abdul Halim ◽  
Nor Azila Muhd Aris ◽  
Muhammad Zikri Fadzil ◽  
Husna Maizura Ahmad Mahir
Keyword(s):  
Clinical Manifestations ◽  
Movement Control ◽  
Epidemiological Data ◽  
Cross Sectional Study ◽  
Effective Control ◽  
Age Group ◽  
District Health ◽  
Cross Sectional ◽  
Notification System ◽  
Co Morbidity

   Background: A COVID-19 cluster named as Rengas Cluster was declared on 6th November 2020 after nine students from a boarding school in Padang Rengas, Perak diagnosed as positive COVID-19. Risk assessment was conducted and Targeted Enhanced Movement Control Order (TEMCO) was enforced at the school to contain the viral transmission. An investigation was carried out to analyze epidemiological data, clinical manifestations among cases and effect of TEMCO on this cluster.  Methods: A retrospective cross-sectional study was conducted from 2nd August 2021 until 3rd September 2021 using data that obtained from Kuala Kangsar District Health Office Crisis Preparedness and Response Centre (CPRC) Surveillance System through e-COVID notification system. The variables used in this current study include socio-demographic and clinical characteristics that include age group, gender, occupation, co-morbidities, symptoms and signs.  Results: There were 132 cases out of 324 exposed populations whereby most cases were students (87.9%) and aged between 11 and 20 years old (84.8%). More than half of cases were female (57.6%) with only one case had existing co-morbidity. Majority of cases were asymptomatic (64.4%). Those symptomatic mainly presented with cough (66%) and the strongest significant positive correlation were observed between anosmia and ageusia (r = 0.807, n = 47, p < 0.001). There was no significant association between age group and development of symptoms [χ2 (6, N = 132) = 6.014, p > 0.05]. An abrupt decline in number of cases was observed following TEMCO enforcement.  Conclusion: COVID-19 cases in Rengas Cluster were mostly among young students, asymptomatic and mildly symptomatic. This cluster was timely and effectively controlled by TEMCO enforcement which contributed towards early diagnosis, isolation and treatment for more effective control and preventive measures. 

scholarly journals PATIENTS SATISFACTION ABOUT HEALTH CARE DELIVERY IN OUT-PATIENTS DEPARTMENT OF COMBINED MILITARY HOSPITAL RAWALPINDI

2020 ◽  
Vol 70 (6) ◽  
pp. 1929-34
Author(s):  
Tahir Sardar ◽  
Iqbal Ahmad Khan ◽  
Muhammed Alamgir Khan
Keyword(s):  
Health Care ◽  
Health Care Delivery ◽  
Care Delivery ◽  
Cost Effective ◽  
Armed Forces ◽  
Cross Sectional Study ◽  
Military Hospital ◽  
Nursing Assistant ◽  
Cross Sectional ◽  
Level Of Satisfaction

Objective: To determine patient’s level of satisfaction and factors leading to dissatisfaction in selected patientsgroup with health care delivery in outpatients department of CMH Rawalpindi. Study Design: Cross sectional study. Place and Duration of Study: Out Patients Department of Combined Military Hospital Rawalpindi, from Sep2013 to Aug 2015. Methodology: Before data collection, written informed consent was taken from all the participants. The studypopulation comprised of armed forces personnel and their families. Patients, including both, males and females, coming to the outpatient department of Combined Military Hospital Rawalpindi were included in the study through consecutive sampling. Results: Results revealed that only 30% were satisfied. 67% patients were satisfied with the facilities in reception and 70% were satisfied with cleanliness in waiting area. A relatively low level of satisfaction with dealing of nursing assistant was recorded while very high percentage of satisfaction with performance of doctor i.e. 91%, examination done by doctor 91% and information provided by doctor 93% was recorded.90% patients reported high level of satisfaction with medicines provided.95.33% patients were satisfied with lab tests being done in hospital. Conclusion: Assessing satisfaction of patients is a simple and cost effective way for assessment of hospitalservices. Most of the patients were contented with services delivered in OPD and showed their trust in doctors,medicines provided and lab facilities offered. Majority were willing to revisit the hospital if required.

scholarly journals A study of etiology of fever of unknown origin in children aged 2 months to 18 years

2021 ◽  
Vol 8 (11) ◽  
pp. 1842
Author(s):  
Naveen Gandla ◽  
Sheela A. Bharani ◽  
Tushar P. Shah
Keyword(s):  
Enteric Fever ◽  
Fever Of Unknown Origin ◽  
Lymphoblastic Leukemia ◽  
Connective Tissue Diseases ◽  
Unknown Origin ◽  
Age Group ◽  
Antimicrobial Drugs ◽  
Cross Sectional ◽  
Female Ratio ◽  
Geographical Regions

Background: In an era of advance science of modern technologies, many diseases are diagnosed and excluded rapidly and now Fever of Unknown Origin (FUO) has been redefined for any fever of 380C lasting for more than 7 days without any clear cause. The aetiology varies according to different geographical regions, socioeconomical status, age, prevalence of resistance to antimicrobial drugs and genetic susceptibility.Methods: It was a descriptive cross sectional, hospital-based study, carried out on 150 children from August 2018 to May 2020. All cases in the age group of 2 months to 18 years with fever of >38.0°C, lasting for more than 7 days without a clear source were included.Results: The mean age of presentation was 5.8 years±Standard Deviation of 3.7 years with male to female ratio was 1.4:1. Nearly half of the cases, presented with the duration of fever between 8-14 days. Enteric fever in 52%, tuberculosis in 13.3% and acute lymphoblastic leukemia (ALL) in 8.5% were three common etiologies found in this study. Amongst all cases of FUO, infective causes were seen in 113 (75.3%) followed by malignancies in 15(10%) cases. In 10 (6.7%) cases, cause could not be established.Conclusions: Enteric fever and tuberculosis were the leading etiologies from infective subgroup of FUO. ALL was the commonest cause from malignancies sub group. FUO presenting with low haemoglobin, platelet is a pointer towards malignancy. Occurrence of FUO with infectious diseases and malignancies was found in younger age group as compared to connective tissue diseases. 

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