scholarly journals Autonomic Dysfunction in Current Cigarette Smokers Assessed by Time Series Analysis of Heart Rate Variability

2014 ◽  
Vol 8 (2) ◽  
pp. 84-88
Author(s):  
Mehboba Ferdouse ◽  
Sultana Ferdousi

Background: Cigarette smoking is one of the strong contributors to the risk of development of cardiovascular diseases including coronary artery disease, stroke, sudden death, peripheral artery disease & aortic aneurysm. Objective: To assess HRV by time domain methods in healthy cigarette smokers. Methods: This cross sectional study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka from July 2011 to June 2012. 120 apparently healthy male current regular cigarette smokers (Group B) aged 20-55 years were enrolled in the study group.70 apparently healthy male non smoker subjects (Group A) were taken as control. Time domain measures of HRV were recorded by a RMS digital Polyrite. Statistical analysis was done by independent sample t test. Results: Resting Pulse, SBP, DBP, Mean heart rate was significantly higher (p<0.001) and Mean R-R interval, SDNN, RMSSD were significantly lower (p<0.001) in all smokers compared to control. Conclusion: Generalized reduced HRV & attenuated cardiac vagal modulation occur in apparently healthy cigarette smokers. DOI: http://dx.doi.org/10.3329/jbsp.v8i2.18659 Bangladesh Soc Physiol. 2013, December; 8(2): 84-88

1970 ◽  
Vol 6 (2) ◽  
pp. 77-83 ◽  
Author(s):  
Sangita Mithun ◽  
Noorzahan Begum ◽  
Sultana Ferdousi ◽  
Shelina Begum ◽  
Taskina Ali

Background: Physical inactivity and low resting heart rate variability (HRV) are associated with increased incidence of coronary heart disease. Heavy physical activity is associated with higher heart rate variability and reduces the risk of coronary heart disease Objective: To assess some time domain measures of HRV in order to compare Cardiac Autonomic Function between sedentary and heavy workers. Methods: This cross sectional study was carried out in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University between 1st July 2008 to 30th June 2009 on 30 apparently healthy heavy workers aged 28-50 years from low socioeconomic condition (study group). For comparison 30 age, sex, BMI and socioeconomic status matched apparently healthy sedentary subjects (group A) were also studied. The study subjects were selected among rickshaw-pullers living in the slum areas nearby BSMMU, Dhaka and the controls were from fourth class employee of BSMMU, Dhaka. Heart Rate Variability were assessed by a Polygraph. Several time domain measures of HRV such as mean R-R interval, mean HR, SDNN, RMSSD were analyzed. For statistical analysis, Independent-Samples t-test, and Pearson’s correlation coefficient tests were done as applicable. Results: Resting mean heart rate (P<0.01), SDNN (P<0.01) and RMSSD (P<0.001) were significantly lower but mean R-R interval (P<0.001) was significantly higher in heavy workers than those of sedentary control. The mean R-R interval (P<0.05) showed significant positive correlation in heavy workers but significant negative correlation in sedentary workers with BMI. Conclusion: Cardiac autonomic nerve function status may be higher with parasympathetic dominance by increased physical activity. DOI: http://dx.doi.org/10.3329/jbsp.v6i2.9755 JBSP 2011 6(2): 77-83


2021 ◽  
Vol 12 ◽  
Author(s):  
Lvming Zhang ◽  
Shi Qiu ◽  
Chunxia Zhao ◽  
Peifu Wang ◽  
Shengyuan Yu

Objective: It has been reported that autonomic nervous dysfunction is more prevalent in migraineurs. Heart rate variability (HRV) is a commonly used method to evaluate the cardiac autonomic nervous function modulation. However, HRV changes in migraine are still contradictory. The main objective of this study was to explore the potential HRV change patterns in episodic migraine (EM) and whether there were differences in HRV between EM ictal period and the interictal period.Patients and Methods: We conducted a cross-sectional study including 18 patients with EM and 18 age- and sex-matched controls. The characteristics of demographics, some lifestyle factors, and psychological conditions were assessed at baseline. HRVs including time-domain analysis and frequency-domain analysis were performed in all participants. HRV analyses in migraine were recorded not only in the interictal period but also in the ictal period.Results: All the HRV parameters showed a decreased trend in migraine than controls. Time-domain parameters standard deviation of all NN intervals in 24 h (SDNN) and triangular index were significantly lower in the migraine ictal period than controls separately (SDNN, 56.94 ± 22.09 ± 7.76 vs. 135.78 ± 35.16, p &lt; 0.001; triangular index, 12.61 ± 3.20 vs. 22.11 ± 6.90, p &lt; 0.001). Frequency-domain parameter low-frequency power was also lower in the migraine ictal period than controls (351.28 ± 206.71 vs. 559.61 ± 281.24, p = 0.02). SDNN was much lower in the migraine ictal period than migraine interictal period (56.94 ± 22.09 vs. 115.94 ± 46.88, p &lt; 0.001). HRV changes during migraine interictal period did not differ from the control group. The correlation analysis revealed a negative correlation between visual analog scale and HRV parameters in the migraine ictal period (p = 0.04).Conclusions: The present cross-sectional study indicates that HRV was significantly decreased in EM population especially during the migraine ictal period, which means unbalance of autonomic system in EM. Perhaps larger prospective cohort studies are wanted to validate these findings.


2018 ◽  
Vol 08 (02) ◽  
pp. 111-122
Author(s):  
Félicité Kamdem ◽  
Yacouba Njankouo Mapoure ◽  
Ba Hamadou ◽  
Fanny Souksouna ◽  
Ahmadou Musa Jingi ◽  
...  

2013 ◽  
Vol 7 (2) ◽  
pp. 78-82 ◽  
Author(s):  
Kawser Jahan ◽  
Noorzahan Begum ◽  
Sultana Ferdousi

Background: Altered cardiovascular autonomic nerve function with impaired sympathovagal balance is found in rheumatoid arthritis (RA). Heart Rate Variability (HRV) analysis is an important tool for assessment of autonomic nerve activity. Objective: To assess cardiac autonomic nerve function status in patients with Rheumatoid arthritis (RA) by time domain measures of HRV. Methods: This cross sectional study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from January to December 2010. Sixty female RA patients, age range 18-50 years were constituted study group enrolled from the Out- patient Rheumatology Wing, Department of Medicine, BSMMU. Age matched thirty apparently healthy females were studied as control. Time domain measures of Heart Rate Variability (HRV) such as Mean RR intervals, Mean HR, SDNN, RMSSD, NN50% and PNN 50% were recorded for 5 minutes by a Polygraph machine to observe cardiac autonomic nerve function activity. Data were analyzed by independent sample t test. Results: Mean R-R interval, SDNN, RMSSD, PNN50%, NN50% were significantly lower (p<0.001) but heart rate was significantly (P<0.001) higher in rheumatoid arthritis patients. Conclusion: Cardiac autonomic nerve function is impaired and characterized by reduced resting parasympathetic activity in female Rheumatoid Arthritis patients. DOI: http://dx.doi.org/10.3329/jbsp.v7i2.14455 J Bangladesh Soc Physiol. 2012, December; 7(2): 78-82


2013 ◽  
Vol 18 (2) ◽  
pp. 27-29
Author(s):  
N Akter ◽  
R Begum ◽  
QS Akhter ◽  
S Shahjadi ◽  
J Akhtar ◽  
...  

Background: Obesity is a common health problem in urban population nowadays. Objective: The present study was carried out to asses the relationship of age with obesity in adult males. Methods: This cross sectional study was done in department of Physiology, Dhaka Medical College, Dhaka. For this purpose, 60 male subjects within the age range of 25 to 50 years were included in the study. Among them 30 non-obese, apparently healthy subjects were selected as control (Group A) and 30 obese subjects as case (Group B). Case and control subjects were selected from the Urban Primary Health Care Project (UPHCP), PA-2, Dhaka City Corporation, Dhaka and by personal contact during the period from January 2010 to December 2010. All the subjects were apparently healthy. Result: In this study, obese males showed significant negative correlation (p=0.032, r= -392) but non obese male showed non-significant (p=0.719, r= +0.069) positive correlation with age. Conclusion: This study concludes that, Serum iPTH level decreases with age in obese males. DOI: http://dx.doi.org/10.3329/jdnmch.v18i2.16019 J. Dhaka National Med. Coll. Hos. 2012; 18 (02): 27-29


2021 ◽  
Vol 71 (3) ◽  
pp. 836-39
Author(s):  
Mehwish Anjum ◽  
Nilofar Mustafa ◽  
Qurratulain Mushtaq ◽  
Pakeza Aslam ◽  
Saima Qamar ◽  
...  

Objective: To compare the frequency of abnormal fetal heart rate in continuous versus discontinuous use of oxytocin infusion for augmentation of labour. Study Design: Comparative cross sectional study. Place and Duration of Study: Department of Obstetrics and Gynaecology, Combined Military Hospital Lahore, from Feb to Aug 2018. Methodology: After fulfilling the inclusion criteria, 76 patients were equally divided in two groups A and B. In both groups, at 3 cm dilatation, intravenous infusion of 5 IU oxytocin in 500 cc normal saline was initiated at infusion rate 3.3mIU/minute Carditocography was initiated 10 minutes before infusion and then continued. An increment in infusion of 3.3mIU/minute was done every 20 minutes till 4 to 5 contractions in 10 minutes were achieved. After this, no more increment was done. The maximum rate was 30mIU/minute. Once cervix was 5 cm dilated, infusion was continued in group A and discontinued in group B for 2 hours. Fetal heart rate was noted on cardiotocography from 20 minutes before initiation of infusion till 2 hours after 5cm. Results: Age of the patients was 25.4 ± 3.5 years in group A and 26.1 ± 2.4 years in group B. Mean gestation age was 39.2 ± 1.1 weeks in group A and 38.6 ± 1.3 weeks in group B. Group A had significantly more abnormal fetal heart rate compared to group B (p=0.016). Conclusion: Discontinuous oxytocin infusion in labour showed significantly less abnormal fetal heart rate compared to continuous oxytocin infusion (p=0.016).


2015 ◽  
Vol 10 (1) ◽  
pp. 36-40
Author(s):  
Shamima Jahan ◽  
Qaz Shamima Akhter

Background: Smoking may cause systemic inflammation, and high level of serum high sensitive Creactive protein may be found in smoker as an indicator of inflammation.Objective: To assess the serum high sensitive C - reactive protein level in male smokers of Bangladesh.Methods: The present cross sectional study was carried out in the Department of Physiology, Dhaka Medical College, Dhaka between July 2013 and June 2014. Hundred apparently healthy male regular cigarette smokers aged 20 to 40 years who smokes at least 5 sticks of cigarette per day for the last 5 years were included as study group. They were further divided in to 5-10 years, 11-15 years, 16-20 years and 1-10 cigarette sticks, 11- 20 cigarette sticks, more than 20 cigarette sticks/day depending on the duration of smoking and also according to consumption of number of sticks/day respectively. Age matched 100 apparently healthy male nonsmokers were included for control. To assess their inflammatory status, serum hs-CRP level was estimated by particles enhanced immunonephelometry using BN Systems in the Department of Microbiology & Immunology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. In addition, BMI and blood pressure were measured by standard method to observe their association with smoking.Results: The mean serum hs-CRP level was significantly higher in male smokers than that of non smokers which was progressively increased with duration of smoking and number of cigarette sticks consumed per day. Again, mean BMI was significantly lower and diastolic blood pressure was significantly higher in male smokers than those of non smokers.Conclusion: The result of this study can be concluded that serum hs-CRP level progressively increases with duration of smoking and number of cigarette sticks consumed per day in male smokers.Bangladesh Soc Physiol. 2015, June; 10(1): 36-40


Author(s):  
Naeimeh Hosseinzadeh ◽  
Alireza Ala ◽  
Sama Rahnemayan ◽  
Elyar Sadeghi-Hokmabadi ◽  
Aylar Gholami Milani ◽  
...  

Objective: The main objective of this study is to evaluate the prevalence of risk factors for and demographics of patients younger than 65 years old with stroke. Methods: This retrospective cross-sectional study took into consideration all patients younger than 65 years old who were admitted to the emergency department from 2016 to 2018. Some significant criteria such as age, sex, type of stroke, stroke risk factors, and modified Ranking Scale (mRS) were extracted from patients’ medical records. Based on their age, these patients were divided into three groups: younger than 35 years old (Group A), between 35-50 years old (Group B), and older than 50 years old (Group C). Data analysis was carried out using IBM® SPSS® Statistics 20.0 software. Results: A total of 392 patients with stroke were included in this study. Groups A, B, and C included 31, 124, and 237 patients, respectively. Among them, 313 patients (79.84%) were admitted to the hospital in cold seasons, while 73 patients (18.6%) had no symptoms related to stroke at the time of admission. The most common adjustable risk factor among the patients was hypertension (HTN) with a frequency of 230 (58.7%). Of note, the frequency of HTN, diabetes, atrial fibrillation (AF), oral contraceptive pill (OCP) consumption, and coronary artery disease (CAD) in patients was significantly different among these three groups. Conclusion: According to the findings of the present study, the prevalence rate of stroke probably varies for male and female (gender) in the studied groups, which is significantly correlated with age. Among the adjustable risk factors for stroke, HTN, diabetes, AF, OCP consumption, and CAD are significantly correlated with the age.


Author(s):  
Rosalía Romero-Tena ◽  
Carmen Llorente-Cejudo ◽  
María Puig-Gutiérrez ◽  
Raquel Barragán-Sánchez

Without having a reaction time, the pandemic has caused an unprecedented transformation in universities around the world, leading to a revolution from structured models anchored in the conception of transmission of training towards a teaching approach-learning saved thanks to the incorporation of technology. This study aims to verify whether the pandemic situation has influenced the digital competence self-perception of students. Comparing two groups during the academic years 2019/2020 and 2020/2021, the instrument used is the questionnaire for digital competence “DigCompEdu Check-In” for future teachers. After the educational intervention, group A (before COVID-19) presented higher self-perceptions of competence than group B (during COVID-19); the pandemic situation caused by COVID-19 has negatively influenced students’ self-perception of their digital skills in the pretest in the different dimensions under study. Before receiving the training, the group that did not experience the pandemic enjoyed a higher self-perception of their competencies than the group that experienced the pandemic. The data obtained indicate that the difference exists, and that it is statistically significant, and may be a consequence of the clear relationship between self-perception and the way in which students face reality through their personal and subjective vision.


Angiology ◽  
2021 ◽  
pp. 000331972110043
Author(s):  
Clemens Höbaus ◽  
Gerfried Pesau ◽  
Bernhard Zierfuss ◽  
Renate Koppensteiner ◽  
Gerit-Holger Schernthaner

We evaluated angiogenin as a prospective biomarker in peripheral artery disease (PAD) patients with and without claudication symptoms. A pilot study suggested an elevation of angiogenin in critical limb ischemia. However, in PAD patients, the predictive value of angiogenin has not yet been evaluated. For this purpose, 342 patients with PAD (age: 69 ± 10 years, 34.5% women) were followed-up for 7 years in a cross-sectional study. Angiogenin was measured by enzyme-linked immunosorbent assay. All-cause and cardiovascular mortality were analyzed by Cox regression. Angiogenin levels were higher in men ( P = .001) and were associated with patient waist-to-hip ratio ( P < .001), fasting triglycerides ( P = .011), and inversely with estimated glomerular filtration rate ( P = .009). However, angiogenin showed no association with age, characteristics of diabetes, markers of lipid metabolism, or C-reactive protein. Angiogenin did not correlate with markers of angiogenesis such as vascular endothelial growth factor, angiopoietin-2, or tie-2. Furthermore, angiogenin was not associated with PAD Fontaine stages or with patient ankle-brachial index in addition to all-cause mortality (hazard ratio [HR] = 1.09 [95% CI: 0.89-1.34]) or cardiovascular morality (HR = 1.05 [0.82-1.35]). These results suggest that angiogenin does not provide further information regarding outcome prediction in patients with PAD.


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