scholarly journals Prevalence of Metabolic Syndrome in Ischemic Heart Disease Patients

2015 ◽  
Vol 23 (2) ◽  
pp. 157-160
Author(s):  
Nafisa Sultana ◽  
Md Saifullah Kabir ◽  
Mohammad Zaid Hossain ◽  
Jesmine Chowdhury ◽  
Shahara Begum ◽  
...  

Ischemic heart disease (IHD) is one of the four leading causes of death globally. An important risk factor for IHD is metabolic syndrome. The definition of metabolic syndrome is not universally agreed. The most commonly used definition was proposed by the National Cholesterol Education Program – Adult Treatment panel III ( NCEP—ATP III ), where metabolic syndrome defined as involving three or more of the following criteria: Blood pressure > 130/85 mm of Hg, fasting blood sugar > 100 mg / dl, triglyceride level > 150mg / dl, high density lipoprotein cholesterol ( HDL-C) < 40mg / dl in men and < 50mg/ dl in women, and abdominal circumference > 102 cm in men and > 88 cm in women.I- which is characterized by clustering of central obesity, hypertension, hyperglycemia and dyslipidemia. This cross sectional analytical study was carried out in the Department of Biochemistry, Dhaka Medical college. The samples were collected from the Department of Cardiology of Dhaka Medical College Hospital (DMCH), Bangladesh Institute of Research on Diabetes Endocrine and Metabolic Disorder (BIRDEM), and National Institute of Cardiovascular Diseases (NICVD), Dhaka, during the period from July 2009 to June 2010. Age distribution of study group shows that majority of the IHD patients with or without metabolic syndrome were in 41-60 years of age group. In the present study the prevalence of metabolic syndrome in IHD patients was found to be 30%. Prevalence was higher in less then 50 years of age group. The prevalence was also higher in female than male.J Dhaka Medical College, Vol. 23, No.2, October, 2014, Page 157-160

KYAMC Journal ◽  
2013 ◽  
Vol 3 (1) ◽  
pp. 223-234
Author(s):  
Md Saiful Islam ◽  
Md Annaz Mus Sakib ◽  
Ranjan Talukder ◽  
Sheikh Mohammed Taslim Yusuf

Background: Echocardiography is a non-invasive, on-injurious, relatively cheap and useful   imaging technique for the evaluation of cardiac diseases. The procedure has reliable levels of  accuracy. Echocardiography commenced at the Cardiology Department of Khawja Yunus Ali   Medical College Hospital,Enayetpur Sirajgonj,Bangladesh since 2004.The aim of this study is to  report our experience with the procedure, and to define the clinical cases seen in our setting.Methods: This is a retrospective analysis of a prospectively collected data. Echocardiography was  performed using Aloka Prosound-SSD 5500 SV echocardiograph equipped with 2.5-5.0 MHz   transducer.  Results: During the period of 6 months under review (July 2011-December 2011), 1883 procedures  were performed. Those reports were reviewed for demographic parameter, indications for the procedure and the main echocardiographic diagnoses. The mean age of the 1883 individuals   studied was 50 +/- 18.67 years (10-90). There were 1221 men and 662 women. Four hundred   ninety eight(498) (26.45%) had Ischemic Heart Disease, 229(12.16%) subjects were Hypertensive Heart disease,160 subjects (8.5%) had rheumatic heart disease while 62,(3.3%) had   cardiomyopathy. Pericardial diseases, corpulmonale, congenital heart diseases, were present in 36(1.92%), 35 (1.85%), 88(4.67%), respectively. Seven hundred and Seventy Five (41.1%) subjects had normal study.   Conclusion: Ischemic heart disease was found to be the most prevalent cardiac condition in this study. The relatively frequent diagnoses of Hypertensive heart Disease, valvular heart disease, cardiomyopathies and pericardial diseases reflect the impact of infections on the cardiovascular   health of adult Bangladeshis. We suggest that prevention and treatment of cardiac diseases in our setting should among other things focus on life style modification, Ceasation of smoking,regular exercise, blood pressure and blood glucose control and early treatment of infections causing heart   diseases.DOI: http://dx.doi.org/10.3329/kyamcj.v3i1.13657KYAMC Journal Vol. 3, No.-1, June 2012 p.223-224


2019 ◽  
Vol 34 (2) ◽  
pp. 122-126 ◽  
Author(s):  
Anisur Rahman Khan ◽  
AKM Azad Hossain ◽  
Md Akteruzzaman ◽  
Sabina Jesmin ◽  
Md Salahuddin Ulubbi ◽  
...  

Background: Ischemic Heart Disease (IHD) is preventable and reversible if early screening and elimination of the risk factors like life style modification and dietary intervention can be done. Exercise Tolerant Test (ETT) has become an important diagnostic tool to evaluate patient with suspected or known case of ischemic heart disease. Objective: To determine the frequency of IHD among subjects who presented with chest pain and to identify the common indications for ETT. Methodology: It was a cross-sectional study; the data was collected from ETT Unit of Mugda Medical College Hospital, Dhaka, Bangladesh using standard Bruce protocol. Result: Out of 200 patients, there were 124(61%) male and 78(39%) female who presented in the cardiology department for ETT. Common indications for ETT were evaluation of chest pain 180(90%), followed by general check-up 14(7%), post-PCI evaluations 4(2%) and post- CABG evaluation 2(1%).Presenting complaints were typical angina 12(6%), shortness of breath 56(28%), nonspecific chest pain 82(41%), chest compression 46(23%) and others 4(2%). Exercise ECG showed no ST changes in 138(69%) patients. The most common risk factors were hypertension, diabetes, smoking and obesity. Majority of the subjects 136(68%) were test negative whereas 42 (21%) were test positive and 22(11%) were test equivocal. Conclusions: It is concluded that most of the subjects presenting with the suspected symptoms of myocardial ischemia were negative for IHD, and so why we advocate the use of ETT as a screening tool in patients who presents with features simulating angina. This will prevent unnecessary hospital admission. Bangladesh Heart Journal 2019; 34(2) : 122-126


2014 ◽  
Vol 7 (1) ◽  
pp. 14-16 ◽  
Author(s):  
BA Ferdous ◽  
N Sultana ◽  
S Ahmed ◽  
EH Khan ◽  
S Sultana ◽  
...  

Risk of coronary heart disease and other forms of atherosclerotic vascular diseases, rises with plasma cholesterol concentration and in particular with the rise of ratio of total cholesterol to high density lipoprotein (HDL-C) cholesterol. A much weaker correlation also exists with plasma triglyceride concentration. Extensive large-scale randomized trials have shown that lowering total cholesterol and LDL-C concentrations reduces the risk of cardiovascular events including death, myocardial infarction and stroke and reduces the need for revascularisation.This cross-sectional analytical study was designed to observe association between lipid profile level with chronic ischaemic heart disease and the study was conducted in the Department of Biochemistry, Dhaka Medical College, Dhaka from July 2010 to June 2011. A total of 50 cases were selected purposively according to the selection criteria from the patients admitted in the Department of Cardiology, Dhaka Medical College Hospital with chronic ischaemic heart disease (IHD). Diagnosed IHD patients were taken as cases and 50 age- & sex- matched healthy subjects were taken as controls. Serum TC, TG, LDL-C & HDL-C were measured in all study subjects.The mean±SD of serum TC, TG, HDL-C and LDL-C concentration in cases were 314.54±73.72 mg/dl, 288.04±60.45 mg/dl, 36.02±4.12 mg/dl, and 178.62±22.7 mg/dl respectively and in controls were 174.64±18.97 mg/dl, 119.42±12.47 mg/dl, 43.04±2.58 mg/dl & 126.28±11.45 mg/dl respectively. Serum Total Cholesterol, TG & LDL-C were found to be significantly higher in cases than that of controls. Serum HDL-C was found to be significantly lower in cases than that of controls. The present study reveals that the patients with chronic ischemic heart disease is accociated with significantly higher levels of serum TC, TG and LDL-C whereas HDL-C was found to be lower in IHD patients. DOI: http://dx.doi.org/10.3329/bjmb.v7i1.18574 Bangladesh J Med Biochem 2014; 7(1): 14-16


2017 ◽  
Vol 26 (4) ◽  
pp. 160-163
Author(s):  
Tania Gudu ◽  
◽  
Alexandra Peltea ◽  
Andra Balanescu ◽  
Violeta Bojinca ◽  
...  

Hyperuricemia is frequent in psoriatic arthritis (PsA) and it seems to be related to metabolic syndrome rather than extensive psoriatic skin disease. The objectives of this study were to evaluate the prevalence of hyperuricemia in PsA patients and to identify the associ-ated factors. Design: cross-sectional study, including consecutive, unselected, adult PsA patients. Data collection: demographic variables (age, gender, disease duration), clinical variables (affected joints, current moderate/severe psoriasis, nail disease, axial involvement, enthesi-tis, dactylitis), laboratory variables (acute phase reactants), treatment-related variables (non-steroidal anti-inflammatory drugs, corticosteroids, synthetic and biologic disease modifying drugs) and comorbidities. Hyperuricemia was defined as uric acid level above 6.8 mg/dl. Statistical analysis: the factors that were potentially associated with hyperuricemia were assessed by uni- and multivariate logistic regression. In all, 120 PsA patients were included in the study: 69 (57.5%) women, mean age±standard deviation 54±11.8 years, mean disease duration 7±7.4 years; 24 (20%) had moderate/severe psoriasis and 30 (25%) were taking a biologic. Around a quarter of patients had hyperuricemia (33; 27.5%). Hyperuricemia was significantly associated with obesity, diabetes, ischemic heart disease and hypertension, but there was no correlation with current skin psoriasis. In the multivariate analysis, it was best explained by diabetes (odds ratio: 4.95, [95% confidence intervals: 1.47; 16.67]), ischemic heart disease (3.61 [1.00; 12.98]) and obesity (1.86 [1.04; 3.32]). Hyperuricemia in PsA is associated with metabolic syndrome rather than skin dis-ease, but further longitudinal studies are needed to identify causal relationships.


2013 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
BA Ferdous ◽  
N Sultana ◽  
S Ahmed ◽  
EH Khan ◽  
F Atia ◽  
...  

C-reactive protein (CRP) is a sensitive marker of inflammation, and elevated levels have been associated with future risk of myocardial infarction (MI). Even elevated CRP in healthy men and women can predict the future coronary events. This cross-sectional analytical study was undertaken to observe association between high hsCRP level with chronic ischaemic heart disease and was conducted in the Department of Biochemistry, Dhaka Medical College, Dhaka from July 2010 to June 2011. A total 50 cases were selected purposively according to the selection criteria form the patients admitted in the Department of Cardiology, Dhaka Medical College Hospital with chronic ischaemic heart disease (IHD). Diagnosed IHD patients were taken as cases; age- and sex-matched 50 healthy subjects were taken as controls. Serum hsCRP and serum TC, TAG, LDL-C and HDL-C were measured in all study subjects. The mean serum hsCRP concentration in cases and controls were 11.22±7.64 mg/dl and 1.72±0.98 mg/dl respectively. Serum hsCRP, Total Cholesterol, TAG and LDL-C were significantly higher in cases than control subjects. Serum HDL-C was significantly lower in cases than control subjects. The present study reveals that the patients of chronic ischemic heart disease have been found to have close association of increased level of hsCRP. DOI: http://dx.doi.org/10.3329/bjmb.v6i1.13281 Bangladesh J Med Biochem 2013; 6(1): 11-13


2016 ◽  
Vol 7 (2) ◽  
pp. 108
Author(s):  
Md. Ashfaqul Islam Chowdhury ◽  
Md. Ismail Patwary ◽  
Md. Matiur Rahman ◽  
M. A. Ahbab

<p><strong>Background:</strong> The common clustering of glucose intolerance, abdominal adiposity, high triglyceride level, low high­density lipoprotein cholesterol level and high blood pressure in a single individual is referred to as Metabolic Syndrome (MS) and it is associated with ischaemic heart disease (IHD). <strong>Objectives:</strong> To find out the relationship between MS and lHD. <strong>Design:</strong> Cross sectional observational study. <strong>Materials:</strong> 100 subjects were selected following simple random sampling technique. 50 patients of MS and another 50 non MS were enrolled as case and controlled respectively in the department of medicine and cardiology at Sylhet M.A. G. Osmani medical college hospital. <strong>Results:</strong> Proportion of IHD was found to be high among the MS (40%) compared to non MS (16%) and the difference was statistically significant (p=0.008) indicating there is a relationship between MS and lliD. Among the components of MS proportion of hyperten­sion (39.2%), diabetes mellitus (41.9%), dyslipidernia (42.6%) and family history of cardiovascular disease (47.1 %) had significant higher association with patients with IHD (p&lt;0.05). <strong>Conclusion:</strong> The MS has a significant association with IHD by electrocardiogram criteria.</p>


2012 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
Sushmita Roy ◽  
S.M. Shamsuzzaman ◽  
K.Z. Mamun

Rotavirus is one of the leading causes of pediatric diarrhea globally. Accurate and rapid diagnosis of Rotavirus diarrhea should reduce unnecessary use of antibiotics and ultimately reduce drug resistance. Study was designed for rapid diagnosis of Rotavirus antigen in stool sample by ICT (Immunochromatographic test) as well as to observe the seasonal variation of rotavirus infection. This cross sectional study was carried out in the department of Microbiology, Dhaka Medical College from January 2011 to December 2011. Eighty stool samples were collected from Dhaka Shishu Hospital and Dhaka Medical College Hospital. All samples were tested for rotavirus antigen by ICT. Among 80 patients, 42 (52.5%) samples were positive for rotavirus antigen. Among these 42 positive samples, 30 (71.43%) were from 0-12 months of age group, 10 (23.81%) from 13 to 24 months of age group and rest 2 (4.76%) from 25 to 36 months of age group. Rotavirus Ag was detected in stool samples from January to April and another peak episode from October to December. Considering the importance of Rotavirus associated diarrhea, rapid detection of Rotavirus infection in human is substantially needed and should be routinely practiced.DOI: http://dx.doi.org/10.3329/bjmm.v6i1.19354 Bangladesh J Med Microbiol 2012; 06(01): 11-13


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