scholarly journals Antibiotic Susceptibility Pattern of Bacterial Pathogens Isolated from Infected Lesions

2019 ◽  
Vol 16 (41) ◽  
pp. 446-451
Author(s):  
Jatan Bahadur Sherchan ◽  
Pranita Gurung
Keyword(s):  
Risk Factors ◽  
Wound Infection ◽  
Antibiotic Susceptibility ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Microbiological Analysis ◽  
Susceptibility Pattern ◽  
Multidrug Resistant Bacteria ◽  
Antibiotic Susceptibility Pattern ◽  
Number Of Patients

Background: Wound infection with multidrug resistant bacteria along with risk factors is a major burden and challenge to the health care persons. This study focuses on antibiotic susceptibility pattern of bacterial isolates and risk factors of patients with infected wounds.Methods: This was a cross-sectional study conducted between November 2017 to June 2018 in Kathmandu University Hospital. Pus sample and wound swabs collected from patients during the study period were included. All microbiological processing were done following standard guidelines and patient’s information was collected following ethical guidelines.Results: Total number of patients observed for wound infection was 2,763. Pathogenic bacteria were detected in 252(9.12%) samples. 167(66.27%) were multidrug resistant. 118(46.82%) had risk factors. Among risk factors 14 had malignancy, 12 had diabetes, 32 were above age 60 without other risk factors, 45 received prior antibiotics and had critical illness and 15 were renal failure patients. Multidrug resistant bacteria was detected more among patients with risk factors 101(85.59%) in comparison to patients without risk factor 66(49.25%). When p value was calculated it was found significant. (p=<0.05).Conclusions: Significant amount of multidrug resistant bacteria were found in wounds of patients with risk factors. Prevention of wound infection by taking care of postoperative wounds, controlling and treating the risk factors, avoiding misuse of antibiotics and early microbiological analysis of infected wound might help to reduce the burden in healthcare centers.Keywords: Extended spectrum beta-lactamase; methicillin resistant staphylococcus aureus; multidrug resistant.

scholarly journals Bacteriological Study of Wound Infection and Antibiotic Susceptibility Pattern of the Isolates

2014 ◽  
Vol 14 (2) ◽  
pp. 143-150
Author(s):  
R KC ◽  
A Shrestha ◽  
VK Sharma
Keyword(s):  
Wound Infection ◽  
Antibiotic Susceptibility ◽  
Klebsiella Oxytoca ◽  
Microbiological Analysis ◽  
Susceptibility Pattern ◽  
Gram Positive ◽  
Bacteriological Study ◽  
Antibiotic Susceptibility Pattern ◽  
Gram Negative ◽  
Staph Aureus

Wound infections result in sepsis, limb loss, long hospital stays, higher costs, and are responsible for significant human mortality and morbidity worldwide. The present study was conducted to isolate and identify the causative organisms of wound infection, to determine the antibiotic susceptibility pattern of the isolates and to study the risk factors for wound infection. The study was conducted for six months in which pus specimens collected from 244 patients were processed to investigate etiological agents using standard technique. Disc susceptibility of bacterial agents were then determined. A total of 244 pus samples were collected and 147 (60.20%) samples showed growth. A total of 150 bacterial isolates were isolated; of which 118 (78.67%) were Gram positive and 32 (21.33%) were Gram negative bacteria. Staphylococcus aureus (72.00%) was most common followed by Escherichia coli (6.67%), Citrobacter freundii (5.34%), Staphylococcus epidermidis (4.00%), Pseudomonas aeruginosa (3.33%), Proteus mirabilis (2.00%), Enterococcus faecalis (1.33%), Acinetobacter spp. (1.33%), Klebsiella oxytoca (1.33%), Klebsiella pneumoniae (1.33%), Streptococcus pneumoniae (0.67%) and Streptococcus pyogenes (0.67%). The most effective antibiotic for Gram positive isolates was Gentamicin (77.97%). For Gram negative isolates (except Ps. aeruginosa), Amikacin (74.07%), for Ps. aeruginosa, Amikacin, Ciprofloxacin, Gentamicin and Ofloxacin each with the susceptibility of 80.00% and for Staph. aureus, Cloxacillin (79.63%) were the most effective antibiotics. Hence, the most common isolate in wound infection was Staph. aureus followed by E. coli. Therefore, routine microbiological analysis of the wound specimens and their antibiotic susceptibility testing is recommended that will guide clinician for treatment of wound infection. DOI: http://dx.doi.org/10.3126/njst.v14i2.10428   Nepal Journal of Science and Technology Vol. 14, No. 2 (2013) 143-150

scholarly journals Occurrence of Antibiotic Resistant Bacteria in Environmental Wastes

Our Nature ◽  
1970 ◽  
Vol 7 (1) ◽  
pp. 151-157
Author(s):  
R.C. Poudel ◽  
D.R. Joshi ◽  
N.R. Dhakal ◽  
A.B. Karki
Keyword(s):  
Staphylococcus Aureus ◽  
Sewage Sludge ◽  
Antibiotic Susceptibility ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Antibiotic Resistant ◽  
Antibiotic Susceptibility Pattern ◽  
Antibiotic Susceptibility Test ◽  
Enterococcus Spp

Microbial resistance to antibiotics has been emerging in environmental isolates. This study was carried out from October 2008 to January 2009 to describe the antibiotic susceptibility pattern of the bacteria isolated from sewage sludge, biowaste and bioslurry samples. A total of 49 identified isolates were taken for antibiotic susceptibility test. Amikacin and Gentamicin were the effective antibiotics for the Gram negative bacteria, comparatively Escherichia coli was the most sensitive. Similarly, all isolates of Staphylococcus aureus and Enterococcus spp. were sensitive to Tetracycline and Erythromycin respectively and none of these isolates were resistant to Vancomycin. Out of 13 S. aureus, five (38.5%) were Methicillin resistant Staphylococcus aureus (MRSA). The multidrug resistant (MDR) isolates accounted for 46.9%, the highest percentage of MDR isolates was seen in Pseudomonas aeruginosa (9/12, 75.0%). The proper management of multidrug resistant bacteria present in waste is suggestive for environmental and public health.Key words: Multidrug resistant bacteria, Bio-waste, Sewage sludge, BioslurryDOI: 10.3126/on.v7i1.2563Our Nature (2009) 7:151-157 

Antibiotic susceptibility pattern against pathogenic bacteria causing Dental Caries

2011 ◽  
Vol 1 (1) ◽  
pp. 31-35
Author(s):  
Deepak Dwivedi ◽  
Tejram Kushwah ◽  
Mukesh Kushwah ◽  
Vinod Singh
Keyword(s):  
Dental Caries ◽  
Antibiotic Susceptibility ◽  
Pathogenic Bacteria ◽  
Resistant Bacteria ◽  
Susceptibility Pattern ◽  
Antibiotic Resistant ◽  
Antibiotic Susceptibility Pattern ◽  
Penicillin V ◽  
Antibiotics Susceptibility ◽  
Susceptibility Tests

Antibiotics to treat dental caries infection are routinely prescribed which led to the increased resistance against bacteria. The purpose of this investigation was to perform antibiotic susceptibility tests on a panel of pathogenic bacteria isolated from dental caries infection. Bacteria were isolated from caries site of patients and identified at the species level. Each of 150 species of bacteria was tested for antibiotics susceptibility to a five antibiotics using Etest. The antibiotics used were Amoxicillin, Cloxocillin, Erythromycin, Tetracycline and Penicillin‐V. The obtained resistance percentage for each antibiotic were Penicillin V: 72/150 (48%), Tetracycline: 99/150 (66%), Amoxicillin: 135/150 (90%), Cloxocillin: 117/150 (78%), and Erythromycin: 90/150 (60%) (Table 1). In case of combinatorial antibiotic exposure, the resistance percentage of Penicillin V/Amoxicillin and Amoxicillin/ Erythromycin was 39/150 (26%), and 45/150 (30%) respectively. The study has well demonstrated the clinical picture of antibiotic resistance and susceptibility pattern of bacteria causing dental caries. The obtained comprehensive data will allow investigating the spatial distribution of pathogenic, antibiotic resistant bacteria among dental caries patients which further may help into development of novel diagnostic and treatment approaches for the same.

SAT-045-Prevalence, type and risk factors of colonization by multidrug-resistant bacteria in a large series of patients with decompensated cirrhosis

2019 ◽  
Vol 70 (1) ◽  
pp. e646-e647
Author(s):  
Maria Hernandez-Tejero ◽  
Fatima Aziz ◽  
Cristina Pitart ◽  
Francesc Marco Reverte ◽  
Irene Campo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multidrug Resistant ◽  
Large Series ◽  
Decompensated Cirrhosis ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria

scholarly journals Pathogenic and Drug Resistant Bacteria in Raw Milk of Jessore City: A Potential Food Safety Threat

2015 ◽  
Vol 13 (1) ◽  
pp. 71-78 ◽  
Author(s):  
UT Tasnim ◽  
MT Islam
Keyword(s):  
Antibiotic Susceptibility ◽  
Microbiological Quality ◽  
Antibiotic Sensitivity ◽  
Raw Milk ◽  
Resistance Pattern ◽  
Resistant Bacteria ◽  
Susceptibility Pattern ◽  
Antibiotic Susceptibility Pattern ◽  
E Coli ◽  
Klebsiella Spp

Milk is such a food which can meet almost all nutritional needs of human lives. Raw or unprocessed milk supports the growth of wide variety of microorganisms. The major interests of this study were examining the microbial quality of raw milk collected from different locations of Jessore city in Bangladesh and determining antibiotic susceptibility pattern of some isolated bacteria. To do so, 12 raw milk samples were collected from different areas of Jessore city. Microbial analysis comprised of enumeration of TVC (total viable count), TCC (total coliform count) and TSC (total staphylococcal count). The highest TVC, TCC and TSC were 1.95x109 CFU/ml, 2.5x107 CFU/ml and 1.02x107 CFU/ml respectively. Prevalent bacterial populations were Klebsiella spp., Enterobacter spp., Shigella spp. Staphylococcus spp., Escherichia coli and Citrobacter spp. In order to observe the antibiotic susceptibility pattern, the antibiotic sensitivity test was performed for some randomly selected isolates of E. coli and Klebsiella spp. More than 90% isolates of Klebsiella spp. were found to be resistant against Erythromycin whereas more than 90% isolates were sensitive against Imipenem. On the other hand, 100% E. coli isolates were observed as resistant against Erythromycin and in case of Trimethopreme 100% isolates were sensitive. Multidrug resistance pattern was also found. These results suggest the necessity of hygienic practices during handling, processing and post-processing of raw milk to improve the microbiological quality and safety of raw milk.DOI: http://dx.doi.org/10.3329/bjvm.v13i1.23723Bangl. J. Vet. Med. (2015). 13 (1): 71-78

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