scholarly journals Impact of dental care on the oral health of in patients with trauma sequelae

2021 ◽  
Vol 10 (8) ◽  
pp. e9610816864
Author(s):  
Maria Patrícia Rogério de Mendonça ◽  
Ana Karisse de Carvalho Andrade ◽  
Manoel de Jesus Rodrigues Mello ◽  
Clarice Maia Soares de Alcântara Pinto ◽  
Paulo Goberlânio de Barros Silva ◽  
...  
Keyword(s):  
Oral Health ◽  
Dental Care ◽  
Adult Patients ◽  
World Health ◽  
Oral Exam ◽  
Spinal Cord Trauma ◽  
Before And After ◽  
Health Organization ◽  
Trauma Sequelae ◽  
The City

This study aims to assess oral health before and after dental care to adult patients restricted to bed with trauma sequelae, admitted to the Instituto Doutor José Frota (IJF) hospital, located in the city of Fortaleza, in the state of Ceará. This is a longitudinal study with adult patients with motor and cognitive disabilities, diagnosis of traumatic brain injury, spinal cord trauma, and exogenous intoxication. We evaluated 39 patients, using the World Health Organization (WHO) dental caries index and Bedside oral exam (BOE) before and after dental care. After two dental consultations, there was a reduction of 46% of decayed teeth, poor oral health decreased by 11% and 29.6% of the BOE index, and good oral health increased by 57%. Although dental care in bed is challenging, it has proved effective, improving the health of the oral mucosa, perioral and dental surfaces and, consequently, reducing the likelihood of changes in oral health.

scholarly journals Management of acute ischemic stroke in patients with COVID-19 infection: Report of an international panel

2020 ◽  
Vol 15 (5) ◽  
pp. 540-554 ◽  
Author(s):  
Adnan I Qureshi ◽  
Foad Abd-Allah ◽  
Fahmi Al-Senani ◽  
Emrah Aytac ◽  
Afshin Borhani-Haghighi ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Current Knowledge ◽  
Intravenous Thrombolysis ◽  
Adult Patients ◽  
World Health ◽  
Stroke Patients ◽  
International Panel ◽  
Health Organization ◽  
Tract Infections

Background and purpose On 11 March 2020, World Health Organization (WHO) declared the COVID-19 infection a pandemic. The risk of ischemic stroke may be higher in patients with COVID-19 infection similar to those with other respiratory tract infections. We present a comprehensive set of practice implications in a single document for clinicians caring for adult patients with acute ischemic stroke with confirmed or suspected COVID-19 infection. Methods The practice implications were prepared after review of data to reach the consensus among stroke experts from 18 countries. The writers used systematic literature reviews, reference to previously published stroke guidelines, personal files, and expert opinion to summarize existing evidence, indicate gaps in current knowledge, and when appropriate, formulate practice implications. All members of the writing group had opportunities to comment in writing on the practice implications and approved the final version of this document. Results This document with consensus is divided into 18 sections. A total of 41 conclusions and practice implications have been developed. The document includes practice implications for evaluation of stroke patients with caution for stroke team members to avoid COVID-19 exposure, during clinical evaluation and performance of imaging and laboratory procedures with special considerations of intravenous thrombolysis and mechanical thrombectomy in stroke patients with suspected or confirmed COVID-19 infection. Conclusions These practice implications with consensus based on the currently available evidence aim to guide clinicians caring for adult patients with acute ischemic stroke who are suspected of, or confirmed, with COVID-19 infection. Under certain circumstances, however, only limited evidence is available to support these practice implications, suggesting an urgent need for establishing procedures for the management of stroke patients with suspected or confirmed COVID-19 infection.

Developmental venous anomaly in adult patients with diffuse glioma

Neurology ◽  
2018 ◽  
Vol 92 (1) ◽  
pp. e55-e62 ◽  
Author(s):  
Alexandre Roux ◽  
Myriam Edjlali ◽  
Sayuri Porelli ◽  
Arnault Tauziede-Espariat ◽  
Marc Zanello ◽  
...  
Keyword(s):  
External Validation ◽  
Adult Patients ◽  
World Health ◽  
Diffuse Glioma ◽  
Developmental Venous Anomaly ◽  
Venous Anomaly ◽  
Control Sets ◽  
Control Set ◽  
Validation Set ◽  
Health Organization

ObjectiveTo determine the prevalence of developmental venous anomaly in adult patients with diffuse glioma.MethodsWe performed a retrospective cohort study (2010–2016) of consecutive adult patients harboring a supratentorial diffuse glioma in 2 centers: Sainte-Anne Hospital (experimental and control sets) and Pitié-Salpêtrière Hospital (external validation set). We included 219 patients with diffuse glioma (experimental set), 252 patients with brain metastasis (control set), and 200 patients with diffuse glioma (validation set). The inclusion criteria were age ≥18 years at diagnosis, histopathologic diagnosis of diffuse glioma according to the 2016 World Health Organization classification of tumors of the CNS, surgery as first-line treatment without previous oncologic treatment, available presurgical MRI performed with similar acquisition protocol, and absence of a nodular-like or a ring-like pattern of contrast enhancement on MRI that may preclude the identification of a possible developmental venous anomaly within the glioma.ResultsWe found more developmental venous anomaly in the experimental set (21.5%) than in the control set (5.2%, p < 0.001). Similarly, we found more developmental venous anomaly in the validation set (23.5%) than in the control set (5.2%, p < 0.001). There was no difference in the developmental venous anomaly prevalence between the experimental and validation sets. The developmental venous anomaly distribution was not significantly associated with histopathologic, molecular, or imaging findings of the diffuse gliomas.ConclusionsWe report and replicate in an external cohort a high prevalence of developmental venous anomaly in adult patients with diffuse glioma, which suggests a potential underlying common predisposition or a causal relationship that requires deeper investigations.

scholarly journals Analysis of the physical aspects of quality of life of kidney recipients

2015 ◽  
Vol 49 (1) ◽  
pp. 76-81 ◽  
Author(s):  
Ana Elza Oliveira de Mendonça ◽  
Marina de Góes Salvetti ◽  
Eulália Maria Chaves Maia ◽  
Ana Cristina de Oliveira e Silva ◽  
Gilson de Vasconcelos Torres
Keyword(s):  
Quality Of Life ◽  
Kidney Transplantation ◽  
Kidney Transplant ◽  
World Health ◽  
Need For Treatment ◽  
Kidney Recipients ◽  
Quality Of Life Scale ◽  
Before And After ◽  
Health Organization

OBJECTIVE To identify the main factors of the physical domain modified after kidney transplantation and analyze the influence of those aspects in the perception of Overall quality of life (QOL). METHOD Longitudinal study, conducted with 63 chronic kidney patients, evaluated before and after kidney transplant, using the quality of life scale proposed by the World Health Organization. RESULTS We observed significant improvement in the physical aspects of QOL after kidney transplantation. Significant correlations were observed between physical aspects and the Overall QOL. CONCLUSION The kidney transplant generated improvement in all physical aspects of QOL. The factors that showed stronger correlation with the Overall QOL before the transplant were the capacity to work and pain. After the transplant, the perception of need for treatment was the factor that showed stronger correlation with the Overall QOL.

scholarly journals Pyrethroid and Etofenprox Resistance in Anopheles gambiae and Anopheles coluzzii from Vegetable Farms in Yaoundé, Cameroon: Dynamics, Intensity and Molecular Basis

Molecules ◽  
2021 ◽  
Vol 26 (18) ◽  
pp. 5543
Author(s):  
Michael Piameu ◽  
Philippe Nwane ◽  
Wilson Toussile ◽  
Konstantinos Mavridis ◽  
Nadja Christina Wipf ◽  
...  
Keyword(s):  
Anopheles Gambiae ◽  
Mortality Rates ◽  
World Health ◽  
Anopheles Coluzzii ◽  
Cross Sectional ◽  
Metabolic Genes ◽  
Anopheles Gambiae S.L ◽  
Underlying Mechanisms ◽  
Health Organization ◽  
The City

Previous studies have indicated widespread insecticide resistance in malaria vector populations from Cameroon. However, the intensity of this resistance and underlying mechanisms are poorly known. Therefore, we conducted three cross-sectional resistance surveys between April 2018 and October 2019, using the revised World Health Organization protocol, which includes resistance incidences and intensity assessments. Field-collected Anopheles gambiae s.l. populations from Nkolondom, Nkolbisson and Ekié vegetable farms in the city of Yaoundé were tested with deltamethrin, permethrin, alpha-cypermethrin and etofenprox, using 1× insecticide diagnostic concentrations for resistance incidence, then 5× and 10× concentrations for resistance intensity. Subsamples were analyzed for species identification and the detection of resistance-associated molecular markers using TaqMan® qPCR assays. In Nkolbisson, both An. coluzzii (96%) and An. gambiae s.s. (4%) were found together, whereas only An. gambiae s.s. was present in Nkolondom, and only An. coluzzii was present in Ekié. All three populations were resistant to the four insecticides (<75% mortality rates―MR1×), with intensity generally fluctuating over the time between mod-erate (<98%―MR5×; ≥98%―MR10×) and high (76–97%―MR10×). The kdr L995F, L995S, and N1570Y, and the Ace-1 G280S-resistant alleles were found in An. gambiae from Nkolondom, at 73%, 1%, 16% and 13% frequencies, respectively, whereas only the kdr L995F was found in An. gambiae s.s. from Nkolbisson at a 50% frequency. In An. coluzzii from Nkolbisson and Ekié, we detected only the kdr L995F allele at 65% and 60% frequencies, respectively. Furthermore, expression levels of Cyp6m2, Cyp9k1, and Gste2 metabolic genes were highly upregulated (over fivefold) in Nkolondom and Nkolbisson. Pyrethroid and etofenprox-based vector control interventions may be jeopardized in the prospected areas, due to high resistance intensity, with multiple mechanisms in An. gambiae s.s. and An. coluzzii.

scholarly journals Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission

2020 ◽  
Vol 134 (16) ◽  
pp. 2137-2160 ◽  
Author(s):  
Daniella S. Battagello ◽  
Guilherme Dragunas ◽  
Marianne O. Klein ◽  
Ana L.P. Ayub ◽  
Fernando J. Velloso ◽  
...  
Keyword(s):  
Signaling Pathways ◽  
Clinical Impact ◽  
World Health ◽  
Current Evidence ◽  
Cellular Interaction ◽  
Crucial Importance ◽  
Future Perspectives ◽  
Organ Systems ◽  
Health Organization ◽  
The City

Abstract The highly infective coronavirus disease 19 (COVID-19) is caused by a novel strain of coronaviruses – the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – discovered in December 2019 in the city of Wuhan (Hubei Province, China). Remarkably, COVID-19 has rapidly spread across all continents and turned into a public health emergency, which was ultimately declared as a pandemic by the World Health Organization (WHO) in early 2020. SARS-CoV-2 presents similar aspects to other members of the coronavirus family, mainly regarding its genome, protein structure and intracellular mechanisms, that may translate into mild (or even asymptomatic) to severe infectious conditions. Although the mechanistic features underlying the COVID-19 progression have not been fully clarified, current evidence have suggested that SARS-CoV-2 may primarily behave as other β-coronavirus members. To better understand the development and transmission of COVID-19, unveiling the signaling pathways that may be impacted by SARS-CoV-2 infection, at the molecular and cellular levels, is of crucial importance. In this review, we present the main aspects related to the origin, classification, etiology and clinical impact of SARS-CoV-2. Specifically, here we describe the potential mechanisms of cellular interaction and signaling pathways, elicited by functional receptors, in major targeted tissues/organs from the respiratory, gastrointestinal (GI), cardiovascular, renal, and nervous systems. Furthermore, the potential involvement of these signaling pathways in evoking the onset and progression of COVID-19 symptoms in these organ systems are presently discussed. A brief description of future perspectives related to potential COVID-19 treatments is also highlighted.

scholarly journals Lebanon Cities’ Public Spaces

2018 ◽  
Vol 3 (1) ◽  
pp. 119-152 ◽  
Author(s):  
Maryam Nazzal ◽  
Samer Chinder
Keyword(s):  
Green Space ◽  
Public Spaces ◽  
World Health ◽  
Right To The City ◽  
Social Connections ◽  
Land Prices ◽  
The Social ◽  
Health Organization ◽  
The Right ◽  
The City

In Lebanon, the social connections are undeniable and crucial. However, meeting places remain private such as houses, restaurants, malls, and beach resorts. This is mainly due to the shortage of public spaces in Lebanon resulting from lack of planning, regulations and awareness around the right to the city and the importance of public spaces. In main cities where land prices are so expensive, common practice has prioritized the use of land in real estate development, thus trumping other uses such as public and communal spaces.In the late 1990s, Lebanon saw the emergence of malls, which have arguably acted as alternatives to public spaces. Malls, with their wealth of food courts, restaurants, cinemas, and play areas, have become the new downtown for a portion of the Lebanese population. They are also considered safe, which is another important factor.In 2015, the percentage of green spaces in Lebanon has decreased to less than 13%. While the World Health Organization (WHO) recommends a minimum of 9m2 of green space per capita (UN-HABITAT, 2016), Beirut has only 0.8m2.

scholarly journals A PIECEWISE GROWTH MODEL FOR MODELING THE ACCUMULATED NUMBER OF COVID-19 CASES IN THE CITY OF CAMPO GRANDE

2021 ◽  
Vol 39 (1) ◽  
pp. 240
Author(s):  
Erlandson Ferreira SARAIVA ◽  
Leandro SAUER ◽  
Basílio De Bragança PEREIRA ◽  
Carlos Alberto de Bragança PEREIRA
Keyword(s):  
Growth Model ◽  
Health Department ◽  
World Health ◽  
Mathematical Study ◽  
Number Of Patients ◽  
Technical Report ◽  
The World ◽  
The Government ◽  
Health Organization ◽  
The City

In December of 2019, a new coronavirus was discovered in the city of Wuhan, China. The World Health Organization officially named this coronavirus as COVID-19. Since its discovery, the virus has spread rapidly around the world and is currently one of the main health problems, causing an enormous social and economic burden. Due to this, there is a great interest in mathematical models capable of projecting the evolution of the disease in countries, states and/or cities. This interest is mainly due to the fact that the projections may help the government agents in making decisions in relation to the prevention of the disease. By using this argument, the health department of the city (HDC) of Campo Grande asked the UFMS for the development of a mathematical study to project the evolution of the disease in the city. In this paper, we describe a modeling procedure used to fit a piecewise growth model for the accumulated number of cases recorded in the city. From the fitted model, we estimate the date in which the pandemic peak is reached and project the number of patients who will need treatment in intensive care units. Weekly, was sent to HDC a technical report describing the main results.

scholarly journals Features of the dental status of athletes of teams of olympic teams as a reflection of the regional level of dental assistance and high psychophysical loads

2020 ◽  
Vol 24 (2) ◽  
pp. 82-86
Author(s):  
Egor E. Olesov ◽  
T. N. Novozemtseva ◽  
I. M. Makeeva ◽  
V. N. Olesova ◽  
M. Ya. Salamov ◽  
...  
Keyword(s):  
Dental Care ◽  
Poor Quality ◽  
Dental Status ◽  
World Health ◽  
Endodontically Treated Teeth ◽  
Dental Examination ◽  
Status Assessment ◽  
Dental Diseases ◽  
Health Organization

The purpose of the study: Comparison of indicators of dental status in athletes of the Olympic national teams and the population of Moscow of the same age.Material and methods: Dental examination of 132 athletes of the Olympic national teams and 104 residents of Moscow, males aged 2035 years was carried out using the modified World Health Organization Dental Status Assessment Card.Results of the study: Analysis of the prevalence and intensity of dental diseases showed that the dental status of athletes is worse in such areas as the detection of previously performed endodontic treatment and its unsatisfactory quality (with more endodontically treated teeth), the detection of large fillings and poor-quality fillings among existing fillings, prevalence pathological abrasion, the prevalence of periodontitis, the detection of unsatisfactory levels of oral hygiene, yyavlyaemost pathology of the temporomandibular joint. The obtained patterns reflect the untimely and insufficient quality of dental care for adolescents-athletes in the regions, as well as indicate higher psychophysical loads in athletes compared to peers. This necessitates special therapeutic and preventive approaches in the implementation of dental care aimed at reducing the parafunctional overload of the dentition in athletes.

scholarly journals Peter Chew Formular for calculate Covid-19 Vaccine efficiency

2021 ◽  
Author(s):  
Peter chew
Keyword(s):  
Relative Risk ◽  
New England ◽  
Target Population ◽  
World Health ◽  
Medical Worker ◽  
The Public ◽  
1 Peter ◽  
The World ◽  
Before And After ◽  
Health Organization

Abstract Background: The World Health Organization (WHO) said the situation in India was a "devastating reminder" of what the coronavirus could do. India shifts from mass vaccine exporter to importer, worrying the world. Every country needs to vaccinate its citizens faster, vaccination can reduce viral load. This results in vaccination that can reduce transmission, preventing serious illness and death'. Therefore, Countries with higher levels of vaccination can prevent them from becoming "Second India".Preprint study, Vaccination Education App (1). [Peter Chew, 2021] shows that most people do not take the covid-19 vaccine because they question the safety and effectiveness of the vaccine. Therefore, it is important to create a simple formula for calculate the efficiency of the covid-19 vaccine. The purpose of creating this calculation formula is to allow the public to calculate the efficiency of the covid-19 vaccine by themselves, so that they can understand the effectiveness of the vaccine and decide to take the vaccine. This helps to get a high response to COVID vaccinationMethods: Use the Data publish at The New England JOURNAL of MEDICINE, Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine [Fernando P. Polack et all , 2020]. Calculate of Pfizer BioNTech’s COVID-19 vaccine efficiency by using normal formular and Peter Chew Formular , show that the same result are obtain, which is 95.0599 %. In addition, By using public news information, the public can use the Peter Chew formula to easily calculate Covid-19 vaccine efficacy. This is to ensure public can do the calculation themselves. A calculation of relative risk is also provided to provide more information to persuade the public to take the vaccine.Results: The efficiency of Pfizer BioNTech's COVID-19 vaccine for Malaysian medical worker calculated by using the Peter Chew formula is 95.0599 %. In addition, the calculation of Peter Chew's formula also shows that before the vaccination, about 12 medical staff were infected every day, but after the full vaccination, only about one medical worker was infected every two days. The calculation of relative risk can also make it easier for the public to know that people who are not vaccinated with Pfizer BioNTech's COVID-19 vaccine are 22 times more likely to be infected than people who are fully vaccinated. The above results can convince those who easily question the effectiveness of vaccination.Conclusions: Peter Chew Formular easy to calculate, and the data required for the Peter Chew Formular calculation easy to obtain from public news. This is to ensure that the public can calculate the efficacy of the vaccine by themselves. The information on the calculation can let public compare the average target group get infected every day before and after fully vaccination is also an advantage to let public know the effectiveness of vaccination. One of the advantage of Peter Chew formulator is that we can assume a high target population of vaccination with k = 100, such as the medical worker group When k = 100, the Peter Chew formular calculation becomes very simple. The Proof of Peter Chew Formular must also be shown.

CORONOVIRUS INFECTION COVID-19. MASKS (literature review)

2021 ◽  
Vol 7 (1) ◽  
pp. 24-32
Author(s):  
Semen Kireev ◽  
I. Popov ◽  
A. Ban'kovskiy ◽  
E. Litvinenko ◽  
E. Surova
Keyword(s):  
World Health Organization ◽  
Infectious Agent ◽  
International Committee ◽  
World Health ◽  
Vulnerable Communities ◽  
Regional Director ◽  
The World ◽  
Coronavirus Infection ◽  
Health Organization ◽  
The City

At the end of 2019, an outbreak of a new coronavirus infection occurred in the People's Re-public of China with an epicenter in the city of Wuhan (Hubei province). On February 11, 2020, the World Health Organization has assigned the official name of the infection caused by the new coronavirus - COVID-19 ("Coronavirus disease2019"). On February 11, 2020, the International Committee on Virus Taxonomy gave the official name to the infectious agent - SARS-CoV-2.Since the end of January 2020, cases of COVID-19 have begun to be registered in many coun-tries of the world, mainly associated with travel to the PRC. At the end of February 2020, the epidemiological situation with COVID-19 in South Korea, Iran and Italy sharply worsened, which subsequently led to a significant increase in the number of cases in other countries of the world associated with travel to these countries, incl. and in Russia. The World Health Organiza-tion announced the COVID-19 pandemic on 11 March 2020, and the pandemic's challenge to the world will remain so as long as people are not immune to it.The Regional Director of the World Health Organization Takeshi Kasai, on the basis of an epidemiological analysis, reports that the spread of coronavirus infection COVID-19 in July-August 2020 occurred mainly among people under 50 years old, and they often did not even know about it, because they had mild or no symptoms. In the future, these people then infect older people who are more difficult to tolerate COVID-19. And we need to redouble our efforts to prevent the spread of the virus in vulnerable communities.

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