scholarly journals Antibiotic residues in honey: a public health issue

2020 ◽  
Vol 9 (11) ◽  
pp. e1739119604
Author(s):  
Clara Mariana Gonçalves Lima ◽  
Flávia Michelon Dalla Nora ◽  
Siluana Katia Tischer Seraglio ◽  
Jiuliane Martins da Silva ◽  
Hercules José Marzoque ◽  
...  

Honey has numerous uses and composes formulations of many food, pharmaceutical, and cosmetic products due to its chemical, biological, and sensorial characteristics. In recent years, several reports and scientific articles claim the contamination of honey by antibiotics, a fact that is a public health problem since the ingestion of them can cause several side effects. In this sense, the purpose of this work was to carry out a literature review in international circulation databases about the contamination of honey by antibiotics in the last 10 years. It is observed in the literature that several quality control methods for evaluating this product have been developed, with the main objective of detecting trace concentrations of these compounds. In this context, the chromatographic techniques, rapid tests, immunoassays, and the use of emerging technologies that are considered sustainable for sample preparation stand out. When these methods are applied to honey samples, it is clear that the contamination of honeys by antibiotic residues has been growing every year, making it evident that programs for continuous monitoring of these residues in honeys are conducted. Also, not only has the amount of antibiotics increased, but also the diversity of assets being used. Regarding the residues present, the main antibiotics found in the evaluated samples belong to the class of tetracyclines, sulfonamides, aminoglycosides, macrolides, and amphenicols. However, few countries report maximum residue limits (MRL) allowed for these substances in honey, and in Brazil, as well as in the European Union, no MRL has been established for antibiotics in this product so far, which indicates that it is extremely important that MRL be adopted to ensure food safety for consumers.

2020 ◽  
Vol 11 (1) ◽  
pp. 54-58
Author(s):  
AKM Farhad Hossain ◽  
Md Mahmudur Rahman Siddiqui ◽  
Sayada Fatema Khatun

Background: Thyroid cancer is the most common malignant disease in endocrine system. It is an emerging public health issue associated with burden on the family, community and the nation. The aim of this study is to determine the socio-demographic and clinical characteristics of patient with thyroid cancer attending in tertiary hospital. Methods: This cross sectional study was conducted among 246 thyroid cancer patients in two tertiary hospitals of Dhaka city from 01 July 2018 to 30 June 2019. The subjects were selected purposively following specific selection criteria and maintaining ethical issues. Data were collected by face to face interview using a semi-structured questionnaire and checklist. Data were analyzed by the statistical package for the social science (SPSS) version 23. Results: This study revealed that majority (74.4%) of respondents was female, married (72%), housewife (61.4%), rural respondent (41.1%) and had primary education (69%). Mean (± SD) age of the respondent was 37.85(±12.20) years (Range 14-70 years) and mean (± SD) monthly family income was Tk. 17681(±10602). Out of 246 cases, 204 (82.9%) was papillary and 42 (17.1%) was follicular carcinoma. Various clinical presentations included visible neck swelling in 225 (91.5%), swollen lymph node in 103 (41.9%), pain 90 (36.6%), Difficulties in swallowing 87 (35.4%), Hoarseness of voice in 141 (57.3%), cough along with swelling 47(19.1%), Difficulties in breathing due to swelling in 13(5.3%) of the patients. Conclusion: Incidence of thyroid cancer has increased worldwide specially in female patients in 3rd and 4th decades of life. As thyroid cancer is a growing public health problem in Bangladesh, proper screening and early diagnostic facilities at all level should be available to measure its actual burden in the country. Anwer Khan Modern Medical College Journal Vol. 11, No. 1: Jan 2020, P 54-58


2021 ◽  
Vol 4 (2) ◽  
pp. 01-04
Author(s):  
Deac Monica

Infec­tious etiology in acute diarrhea, referred several gastrointestinal diseases, Most are gastroenteri­tis associated with clinical signs and symptoms including: nausea, vomiting, abdomi­nal pain and cramps, bloating, flatulence, fever, passage of bloody stools, tenesmus, and fecal ur­gency disorders. Diarrheal illness is a large worldwide public health problem, with substantial regional variation, in the prevalence of medical signs by being caused by specific pathogens. Infectious diarrheal diseases, are the second leading cause of morbidity and mortality worldwide and can cause real public health concerns. Such diarrhea was studied as a medical disorder, in a 3 years period, 2017 to 2020, in Transylvania a large region in Romania. It was found there, 3577 number of diarrheal diseases cases, appeared almost during July to August. The case incidence for the disease arrived at 65%, in the entire summer season. The cases data were transmitted by 12 district Sanitary Polices, to the Public Health Center Cluj. Cases were almost diagnosed by the family doctors of the region, in more then 50%. Few of this have need some days of hospitalization, because of several disease disorders, in which case it was used a specific adequate fluid and electrolyte replacement as key of the treatment, for managing diarrheal illnesses. Even so, 3 children under 5 years age died, because of severe complications. It was remarked so, organic failed who was estimate to be the cause of their deaths. Clinical and epidemiological evaluations were done and even defined the severity and type of this mentioned illnesses. The detected infectious etiology for the acute diarrheas, where determined in authorized Microbiology laboratories, where were identified: Shigella spp, Salmonella spp, Campylobacter spp, Yersinia spp, Rotavirus, Giardia. Most number of cases appeared in children, being suggestive in 63%, followed by elderly or adult people in 17% each. Acute diarrheal illness had to be considered a major public health issue, against which some determined control efforts are needed. Public health surveillance of infectious acute diarrhea, includes obligatory done strategies for a correct infection control.


Author(s):  
Butool Hisam ◽  
Mohammad Nadir Haider ◽  
Ghazala Saleem ◽  
Admin

We are observing with great concern the global spread of the COVID19 Pandemic. What is equally alarming is a less visible, albeit serious Public health issue; one that the United Nations has dubbed as the ‘Shadow Pandemic’ [1]. This is none other than the globally prevalent issue of violence against women, particularly Intimate Partner Violence. Intimate Partner Violence (IPV) is a serious, possibly preventable public health problem globally. Pakistan ranks among the countries with the highest IPV rates [2]. On 11th March 2020, the World Health Organization declared the highly infectious and lethal Severe Acute Respiratory Syndrome Coronavirus 2 (COVID-19) to be a pandemic [3]. Drastic measures were enforced universally to curb the spread of COVID-19. Countries issued strict nationwide lockdowns to isolate the population and implemented social distancing. The economy was impacted tremendously, and many people experienced financial and emotional hardship during this mandatory confinement. While everyone was affected, one population was in a far worse situation than others. Survivors of IPV were trapped alongside their perpetrators and faced difficulty/less freedom to escape threatening situations compared to the past. It is not surprising given that historical periods of uncertainty such as war or economic crisis have resulted in increased interpersonal violence, including violence against women [4].  The Hubei province of China, the first region to undergo a lockdown, saw nearly a doubling of their rates of IPV with the start of COVID19 Pandemic.  Similarly, tragic stories gained nationwide coverage in the United States. IPV may also have risen in Pakistan, even if it is not being covered as extensively. During pandemics, fear causes us to minimize our personal needs and make sacrifices we would not normally make. This could be a reasonable approach for most but should not be for survivors of IPV. IPV survivors live in constant fear for themselves and their children; they are now devoid of their only means of mitigation; avoidance. Local woman’s support groups in Pakistan should act and spread awareness about this grim reality hiding underneath the Pandemic. Resources/funding should be made available for survivors to be able to reach out for support without having to leave the watchful eyes of their perpetrators. Public health officials ought to investigate and document the rise in IPV to help identify the leading causes of the increase. These steps will assist in developing crisis-specific guidelines to provide adequate resources for the future. Continuous....


2019 ◽  
Vol 6 ◽  
pp. 233339281987655 ◽  
Author(s):  
Moriam Khanam ◽  
Shafiun N. Shimul ◽  
Abdur Razzaque Sarker

Introduction: Childhood undernutrition is a crucial public health problem globally. The objective of this study is to measure the prevalence of childhood undernutrition and assess the distinct role of various factors on childhood undernutrition in Bangladesh. Methods: This study utilized the latest cross-sectional data from Bangladesh Demographic and Health Survey 2014. A total of 7256 data on children younger than 5 years old were analyzed. The undernutrition status of children was assessed by stunting (height-for-age), wasting (weight-for-height), and underweight (weight-for-age), while bivariate and multivariate analyses were performed to identify various individual-, household-, and community-level factors of childhood undernutrition. Results: The prevalence of stunting, wasting, and underweight were 36.5%, 14.6%, and 32.5%, respectively. Along with various individual- and household-level factors (eg, age, recent diarrheal disease, fever, number of under-5 children in the household, mother’s education and nutritional status, and wealth status), community index, particularly regional and geographic variation of community, had significant role for childhood undernutrition in Bangladesh. Conclusion: Childhood undernutrition is an overwhelming public health issue in Bangladesh. In order to improve the nutritional status of under-5 children, interventions should take into account the various predictors discussed in this study. Indeed, a joint effort by the government, nongovernmental organizations, and the community is necessary to improve the childhood nutritional status in Bangladesh.


2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
Y El Harrak ◽  
N Boutimzine ◽  
L O Cherkaoui

Abstract Occupational eye trauma is a global cause of visual morbidity. According to the WHO, 55 million ocular lesions occur each year, and 1.6 million cases of total blindness caused by trauma. Although common in Morocco, these traumas have not been the subject of recent and targeted investigations. The objective of our work is to evaluate the frequency of occupational eye trauma per projectile, and to encourage the reinforcement of safety measures. This is a cross-sectional descriptive study, carried out in the Ophthalmic Emergency Department, at the University Hospital of Rabat, Morocco, and including all patients who presented to the same doctor’s consultation, between December 2016 and December 2018. The study involved 914 patients, 406 women and 508 men, with an average age of 36. The average consultation time is 35 days after the onset of symptomatology. In 2 years, and out of 914 people, 382 (42%) are victims of ocular trauma; and 167 are victims of projectile eye trauma during professional practice, an overall prevalence of 18%, or 51% of all trauma. The average age was 32 years, 92% of males. The average consultation time was 2 days after the accident. In addition, 75% of consultants for occupational eye trauma have a similar history of trauma, 3 out of 4 people. As a consequence, the study shows that 85% of these patients had a superficial corneal foreign body; 11% presented with a corneal ulcer without individualization of a foreign body; while 4% of these had a corneal wound, an intraocular foreign body and posttraumatic retinal detachment. Therefore, eye trauma is a real public health problem. They account for 42% of consultations, half of which are associated with professional activities, mainly affecting young and active men. If they are benign in most cases, these traumas can nevertheless cause blindness in 4%. The high number of recidivism (75%) highlights the lack of awareness of the target population for better prevention. Key messages The results of this work prove that occupational ocular trauma, avoidable circumstances, are however frequent in our context and can cause severe lesions, with a reserved prognosis. Workplaces with a high risk of eye trauma should strengthen their protective measures and training programs should be put in place for both workers and occupational physicians.


Author(s):  
David Clarke

There has been slow progress with finding practical solutions to health systems corruption, a topic that has long languished in policy-makers "too difficult tray." Efforts to achieve universal health coverage (UHC) provide a new imperative for addressing the long-standing problem of corruption in health systems making fighting corruption at all levels and in all its forms a priority. In response, health system corruption should be classified as a risk to public health and addressed by adopting a public health approach. Taking a public health approach to health systems corruption could promote a new paradigm for working on health system anti-corruption efforts. A public health approach could increase the space for policy dialogue about corruption, focus work to address corruption on prevention, help generate and disseminate evidence about effective interventions strategies, and because of its focus on multisectoral action would provide new opportunities for promoting cooperation on anti-corruption work across multiple agencies and sectors. Using a public health approach to tackle health system corruption could help address the current inertia around the topic and create a new positive mindset among policy-makers who would come to see corruption as a manageable public health problem rather than an intractable one.


2021 ◽  
Vol 9 (12) ◽  
pp. 2436
Author(s):  
Nattamol Phetburom ◽  
Parichart Boueroy ◽  
Peechanika Chopjitt ◽  
Rujirat Hatrongjit ◽  
Yukihiro Akeda ◽  
...  

Dissemination of the mobile colistin resistance gene mcr in Enterobacterales among humans, animals, and the environment is a public health issue. We characterized mcr genes in the Klebsiella pneumoniae complex (KpnC) isolated from slaughtered pigs in Thailand. The 280 KpnCs consisted of K. pneumoniae (85%), Klebsiella quasipneumoniae (8.21%), and Klebsiella variicola (6.79%). mcr genes were detected in 6.79% (19/280) of KpnC isolates, consisting of mcr-8 (n = 9; 3.21%), mcr-7 (n = 7; 2.50%), mcr-7 + mcr-8 (n = 2; 0.71%), and mcr-1 + mcr-7 (n = 1; 0.36%). K. pneumoniae predominantly carried the mcr-7 and mcr-8 genes, while K. variicola and K. quasipneumoniae harbored mcr-7 and mcr-8, respectively. Six of the nineteen mcr-harboring KpnC isolates exhibited colistin resistance, and five had mcr-1 or mcr-8 transferable to an Escherichia coli recipient. Antimicrobial susceptibility analysis revealed that all mcr-carrying KpnC isolates were susceptible to carbapenems, cefotaxime, cefepime, amoxicillin/clavulanic acid, piperacillin/tazobactam, amikacin, and fosfomycin, and had high resistance to azithromycin. Multilocus sequence analysis demonstrated that the mcr-harboring KpnC isolates were genetically diverse. A ‘One-Health’ approach is useful to combat antimicrobial-resistant bacteria through coordinating the human, animal, and environmental sectors. Hence, continuous monitoring and surveillance of mcr-carrying KpnCs throughout the pork supply chain is crucial for ensuring public health.


2017 ◽  
Vol 4 (3) ◽  
pp. 1067
Author(s):  
Ranganatha A. Devaranavadagi ◽  
Srinivasa S.

Background: Typhoid fever is caused by Salmonella typhi. It is a major public health problem in India. Typhoid fever is endemic in many developing countries. Wide variations in the clinical manifestations of typhoid fever make its diagnosis a challenging task. This study was conducted to understand the wide range of clinical manifestations, complications and antibiotic sensitivity patterns of typhoid fever in children.Methods:Prospectively, 113 children admitted in pediatric unit with confirmed Typhoid fever from September 2015 to December 2016 at KIMS hospital, Bangalore were included. In each case, age, sex, presenting complaint, laboratory investigations and antibiotic sensitivity pattern are collected and analysed.Results: Out of 113 cases, 72 cases (63.8.1%) were males, 41 cases (36.2%) were females. The most common age group was 5-10 years. The most common symptom was fever, seen in 100% cases, followed by anorexia (61%), vomiting (44%) and abdominal pain (18%). The most common sign observed was toxic look in 68% of the cases, followed by coated tongue in 49% and hepatomegaly in 44%. Leucocytopenia was found in 34% of cases. Eosinopenia was found in 39% of cases. Anaemia was found in 16% of cases. Thrombocytopenia was found in 15% of cases. Blood culture was positive in 20% of cases. Use of municipal water for drinking was found in 65% of cases. Outside eating was found in 40% of cases. Unhygienic practices were found in 64% of cases. Duration of hospital stay varied from 3-10 days. No mortality reported.Conclusions:Typhoid fever is most commonly observed with unhygienic practices and eating of unhealthy outside food. This major public health issue can be tackled by bringing awareness among people regarding disease transmission and its various preventive measures. 


2021 ◽  
Vol 6 (3) ◽  

From medical point of view, “Diarrhea” is an alteration in a normal bowel movement characterized by an increase in the water content, volume, or frequency of stools. Acute diarrhea of infec¬tious etiology, often referred to as gastroenteri¬tis and is typically associated with clinical signs and symptoms including: nausea, vomiting, abdomi¬nal pain and cramps, bloating, flatulence, fever, passage of bloody stools, tenesmus, and fecal ur¬gency. Infectious diarrheal diseases are the second leading cause of morbidity and mortality worldwide. It is the diarrhea we have also found out, during a large 3 yeas study 2017-2020 in Transylvania – Romania. 3577 number of cases were transmitted during this time, to our Public Health Center, by 12 district Sanitary Polices. These were mostly diagnosed by the territorial family doctors and more then 50%, have need hospitalization, for several days because of the mentioned disease disorders. The detected infectious etiology, were determined in authorized laboratories in which it was identified: Shigella, Salmonella, Campylobacter, and Yersinia, Rotavirus, Giardia. Most number of cases appeared in children, followed by elderly or adult people, as quantified number of determination. In light of these data, acute diarrheal illness had to be considered a major public health issue against which control efforts are needed. Public health surveillance and response in the field of infectious acute diarrhea include obligatory strategies of infection control.


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