Morbidity of children with diseases of the endocrine system, eating disorders and metabolic disorders in the Khabarovsk Krai: current situation and trends

2020 ◽  
Vol 1 ◽  
pp. 4-10
Author(s):  
L.K Prisyazhnyk ◽  
◽  
K.P. Topalov ◽  
Keyword(s):  
Eating Disorders ◽  
Metabolic Disorders ◽  
Endocrine System ◽  
Current Situation ◽  
Khabarovsk Krai

scholarly journals Features of metabolic disorders in chromium mine workers

2021 ◽  
Vol 100 (10) ◽  
pp. 1095-1102
Author(s):  
Nina V. Zaitseva ◽  
Vitalii G. Kostarev ◽  
Konstantin P. Luzhetskiy ◽  
Alexander E. Nosov ◽  
Olga Yu. Ustinova ◽  
...  
Keyword(s):  
Working Conditions ◽  
Metabolic Disorders ◽  
Comparison Group ◽  
Visceral Obesity ◽  
Endocrine System ◽  
Atherogenic Index ◽  
Observation Group ◽  
Accumulation Coefficient ◽  
Noise Vibration ◽  
Metabolic Indices

Introduction. Working conditions, clinical and laboratory status of 236 workers of a chromium mine were investigated. Materials and methods. The observation group included 162 underground employees working in conditions of the combined impact of negative occupational factors (dust, noise, vibration, tension and severity there, cooling microclimate) - class 3.3-3.4. The comparison group included 74 mine employees working in acceptable working conditions - class 2. Results. In the observation group, the pathology of the cardiovascular and endocrine system (ICD-10: I00-I99, E00-E07) was detected 2.8-3.3 times more often (p = 0.001-0.02), the relative risk of disease formation was 2.7-3.2 times higher than in the comparison group (RR = 2.7-3.2; DI = 1.44-9.2; p = 0.001-0.02). Under the conditions of the combined effect of negative production factors, as features of metabolic disorders, it was noted that the most unfavourable - abdominal form of obesity was diagnosed 1.4 times more often (42.0%, p = 0.013), the atherogenic index was 1.2 times higher, and the level HDL is 1.2 times lower than in the comparison group (p = 0.017-0.047); “Metabolic indices” - lipid accumulation coefficient (LAP) and visceral obesity index (VAI) were 1.2-1.4 times higher than the values in the comparison group (p = 0.001-0.048). Conclusions. To implement a complex of medical and preventive measures aimed at increasing life expectancy and working longevity, early prevention of CVD, including among those working in the extraction of chrome ore, it is advisable to consider the introduction of the calculation of early markers of metabolic disorders - VAI and LAP indices in the medical examination programs.

scholarly journals THE ENDOCRINE METABOLIC DISORDERS IN CHILDREN OF FEMALE WORKERS OF NUCLEAR ENERGETICS ENTERPRISE

2019 ◽  
Vol 62 (4) ◽  
pp. 211-219
Author(s):  
Svetlana F. Sosnina ◽  
P. V. Okatenko
Keyword(s):  
Gamma Radiation ◽  
Metabolic Disorders ◽  
Endocrine System ◽  
Absorbed Dose ◽  
Nuclear Industry ◽  
Factorial Analysis ◽  
Reproductive Age ◽  
Medical Documentation ◽  
Malignant Neoplasms ◽  
Female Workers

The article presents the results of evaluation of post-natal deviations in offspring of individuals underwent irradiation exposure at work that testify necessity of supporting radiation security of personnel of reproductive age. Purpose of study. To analyze endocrine metabolic disorders in children of female workers of nuclear industry having cumulated pre-conceptive doses of external gamma-radiation. Material and methods. The retrospective analysis was carried out concerning data of medical documentation of 1190 children prior to age of 15 years old. Out of them, 238 children were offspring of mothers underwent radiation exposure at work. The methods of non-parametric statistics were applied. The factorial analysis method of principal components was applied to establish latent factors. Results. The range of pre-conceptive doses of external gamma-radiation of gonads of mothers made up to 0,09-3523,7 mGy and average absorbed dose on gonads made up to 373,6 ± 34,2 mGy. In the groups, no significant differences in rate of endocrine metabolic pathology were established. In the structure of class "Diseases of endocrine system, nutrition disorders and metabolic imbalance" prevalence of rickets and malnutrition of children of early age were established. In the group of offspring of radiation exposed mothers, a statistically reliable exceeding of both thyroid pathology in general and iodine-deficiency conditions was established with main input of sub-group of girls. There was no evidence of autoimmune endocrine pathology and malignant neoplasms of thyroid gland in the examined groups. The factorial analysis in the group of offspring of female workers of nuclear industry marked out five factors characterizing feeding of infant of the first year of life (dispersion 25.5%), obstetrical anamnesis of mothers (dispersion 11.1%), harmful habits of mothers (dispersion 9.8%), anthropometric status of newborns (dispersion 7.3%) and pre-conceptive irradiation of mothers (dispersion 6.2%). The higher factorial load of variable "dose on gonads" (0.8) is demonstrated. Conclusion. The presented characteristics can be used for early detection of endocrine metabolic disorders in offspring of irradiation exposed mothers in case of dispensary observation.

FEATURES OF THE DEVELOPMENT OF METABOLIC VIOLATIONS IN CHILDREN POPULATION, RESIDING IN CONDITIONS OF CHRONIC PERORAL EXPOSURE OF CHLORORGANIC COMPOUNDS

2018 ◽  
pp. 40-44
Author(s):  
K.P. Luzhetsky ◽  
O.Yu. Ustinova ◽  
S.V. Kleyn ◽  
A.Yu. Vandysheva ◽  
S.A. Vekovshinina
Keyword(s):  
Drinking Water ◽  
Metabolic Disorders ◽  
Endocrine System ◽  
Resistance Index ◽  
Carcinogenic Risk ◽  
Oral Exposure ◽  
Excess Body Weight ◽  
Long Time ◽  
Group A ◽  
High Concentrations

Sanitary and hygienic analysis of drinking water quality was carried out and health risk assessment of the population living in the industrial areas of the Perm region and consuming drinking water with high content of organochlorine compounds (Tetrachloromethane to 3.7 MPC, chloroform to 2.8 MPC). In the conditions of oral exposure to COC in the population formed unacceptable non-carcinogenic risk of endocrine system pathology (HI = 1.72, due to the influence of chloroform (85.7 %). In exposed children with high concentrations of chloroform and Tetrachloromethane in the blood, endocrine system pathology was diagnosed 2,0–2,4 times more often, the relative risk of obesity (E66.0) and redundant power supply (E67.8) 2.4 times higher than the indicators of the comparison group. A reliable causeand– effect relationship between the development of metabolic disorders (obesity and overweight) and the consumption of drinking water with high content of chos (OR = 2,4; DI = 1,05–6,8) was established; the proportion of the explained variance was R2 = 0,3–0,34; 85,4 ≤ F ≥ 112,8; p < 0,001. As features of the development of metabolic disorders in the population for a long time consuming drinking water with high content of chos (Tetrachloromethane, chloroform) revealed a sharp disharmony of physical development, early formation of excess body weight and obesity, an increase of 1,4–1,6 times the level Of C-peptide and leptin in the blood, insulin resistance index HOMA-IR, (p < 0,05).

scholarly journals On the state of child health in Ekaterinburg based on results of prophylactic medical examinations

2020 ◽  
Vol 1 (2) ◽  
pp. 25-30
Author(s):  
L. V. Rozhkova ◽  
S. A. Tsarkova ◽  
E. V. Savelyeva ◽  
M. M. Arkhipova ◽  
O. U. Sevostianova ◽  
...  
Keyword(s):  
Digestive System ◽  
Metabolic Disorders ◽  
Population Distribution ◽  
Pediatric Population ◽  
Connective Tissue Diseases ◽  
Endocrine System ◽  
Fold Increase ◽  
Medical Rehabilitation ◽  
Healthy Children ◽  
Medical Examinations

Morbidity parameters in children aged 0–17 years have been analyzed based on results of prophylactic medical examinations conducted in Ekaterinburg between 2013 and 2019. The prophylactic medical examination coverage of pediatric population, distribution among the health status groups and frequency of regular medical check-ups have been studied. In 2019 versus 2013, children aged 0–17 years demonstrated a 1.6-fold increase in overall morbidity, and 2.3-fold increase in primary-care morbidity. In 2013–2017, a higher level of overall morbidity was found in children aged 15–17 years compared to children 0–4 years of age, owing to the emergence of newly diagnosed diseases. It was noted than the most frequently diagnosed diseases included diseases of the musculoskeletal system and connective tissue, diseases of the eye and eye appendages, diseases of nervous system, digestive system, endocrine system, nutritional disorders and metabolic disorders. Each year, based on results of prophylactic medical examinations, the proportion of children for whom the outpatient examination has been recommended amounts to 9.5%, outpatient treatment to 35.0%, and outpatient medical rehabilitation to 9.3%. The fraction of healthy children as of 2019 was 23.1% of all examined children. In 2019 the coverage for medical check-ups at the health facilities was 605.6 per 1000 children, that is 1.8 times higher than that in 2013 (334,0 per 1000 children).

scholarly journals On the state of child health in Ekaterinburg based on results of prophylactic medical examinations

2020 ◽  
Vol 1 (2) ◽  
pp. 25-30
Author(s):  
L. V. Rozhkova ◽  
S. A. Tsarkova ◽  
E. V. Savelyeva ◽  
M. M. Arkhipova ◽  
O. U. Sevostianova ◽  
...  
Keyword(s):  
Digestive System ◽  
Metabolic Disorders ◽  
Population Distribution ◽  
Pediatric Population ◽  
Connective Tissue Diseases ◽  
Endocrine System ◽  
Fold Increase ◽  
Medical Rehabilitation ◽  
Healthy Children ◽  
Medical Examinations

Morbidity parameters in children aged 0–17 years have been analyzed based on results of prophylactic medical examinations conducted in Ekaterinburg between 2013 and 2019. The prophylactic medical examination coverage of pediatric population, distribution among the health status groups and frequency of regular medical check-ups have been studied. In 2019 versus 2013, children aged 0–17 years demonstrated a 1.6-fold increase in overall morbidity, and 2.3-fold increase in primary-care morbidity. In 2013–2017, a higher level of overall morbidity was found in children aged 15–17 years compared to children 0–4 years of age, owing to the emergence of newly diagnosed diseases. It was noted than the most frequently diagnosed diseases included diseases of the musculoskeletal system and connective tissue, diseases of the eye and eye appendages, diseases of nervous system, digestive system, endocrine system, nutritional disorders and metabolic disorders. Each year, based on results of prophylactic medical examinations, the proportion of children for whom the outpatient examination has been recommended amounts to 9.5%, outpatient treatment to 35.0%, and outpatient medical rehabilitation to 9.3%. The fraction of healthy children as of 2019 was 23.1% of all examined children. In 2019 the coverage for medical check-ups at the health facilities was 605.6 per 1000 children, that is 1.8 times higher than that in 2013 (334,0 per 1000 children).

scholarly journals Endocrine and metabolic consequences of surgical interventions in uterine myoma: pathogenetic characteristic

2019 ◽  
Vol 10 (2) ◽  
pp. 75-82
Author(s):  
Lali. I. Chaava ◽  
Ekaterina I. Kakhiani ◽  
Vasiliy N. Tsygan ◽  
Alexey N. Drygin ◽  
Maria A. Pakhomova
Keyword(s):  
Metabolic Disorders ◽  
Endocrine System ◽  
The Body ◽  
Uterine Myoma ◽  
Psychological Status ◽  
Endocrine Disorders ◽  
Surgical Interventions ◽  
Uterine Myomas ◽  
Female Sex Hormones ◽  
Organ Systems

This paper presents analysis results of the research on endocrine and metabolic disorders in women who underwent surgery interventions for uterine myomas. Uterine myoma is one of the most common gynecological diseases. Main types of surgical interventions to treat uterine myomas are: hysterectomy, which is an organ-removing operation with various volume of surgical intervention: supravaginal amputation or extirpation of the uterus. Another type is myomectomy — an organ-preserving operation — when myoma nodes are removed, but the uterus and ovaries are preserved if they have no pathology. Removal of the uterus with appendages or without ovaries results in a decreasing production of estrogens, which play a key role in regulation of metabolism and various functions of the body systems. Estrogen deficiency, occurring after hysterectomy, deprives patients of a comprehensive protective effect of female sex hormones in all types of metabolism and normal functioning of organ systems. Hypoestrogenemia leads to development of a post-hysterectomy syndrome that comes out in early development of atherosclerosis, circulatory diseases, osteoporosis, psychological status disorders and urogenital disorders. Hypoestrogenemia is a key link in the pathogenesis of endocrine and metabolic disorders after hysterectomy. Endocrine disorders can be found at almost all levels of the regulatory and executive axis of the endocrine system. So far, hormonal function of the peripheral endocrine glands after myomectomy has been poorly studied. Currently available publications give no data on endocrine and metabolic disorders in patients after the myomectomy.

scholarly journals On the state of child health in Ekaterinburg based on results of prophylactic medical examinations

2020 ◽  
Vol 1 (2) ◽  
pp. 25-30
Author(s):  
L. V. Rozhkova ◽  
S. A. Tsarkova ◽  
E. V. Savelyeva ◽  
M. M. Arkhipova ◽  
O. U. Sevostianova ◽  
...  
Keyword(s):  
Digestive System ◽  
Metabolic Disorders ◽  
Population Distribution ◽  
Pediatric Population ◽  
Connective Tissue Diseases ◽  
Endocrine System ◽  
Fold Increase ◽  
Medical Rehabilitation ◽  
Healthy Children ◽  
Medical Examinations

Morbidity parameters in children aged 0–17 years have been analyzed based on results of prophylactic medical examinations conducted in Ekaterinburg between 2013 and 2019. The prophylactic medical examination coverage of pediatric population, distribution among the health status groups and frequency of regular medical check-ups have been studied. In 2019 versus 2013, children aged 0–17 years demonstrated a 1.6-fold increase in overall morbidity, and 2.3-fold increase in primary-care morbidity. In 2013–2017, a higher level of overall morbidity was found in children aged 15–17 years compared to children 0–4 years of age, owing to the emergence of newly diagnosed diseases. It was noted than the most frequently diagnosed diseases included diseases of the musculoskeletal system and connective tissue, diseases of the eye and eye appendages, diseases of nervous system, digestive system, endocrine system, nutritional disorders and metabolic disorders. Each year, based on results of prophylactic medical examinations, the proportion of children for whom the outpatient examination has been recommended amounts to 9.5%, outpatient treatment to 35.0%, and outpatient medical rehabilitation to 9.3%. The fraction of healthy children as of 2019 was 23.1% of all examined children. In 2019 the coverage for medical check-ups at the health facilities was 605.6 per 1000 children, that is 1.8 times higher than that in 2013 (334,0 per 1000 children).

To the question about the prevalence of prenosological forms of eating disorders among students of a medical university

2020 ◽  
pp. 47-53
Author(s):  
Anna Aleksandrovna Voitovich ◽  
Taisiya Valerievna Milashevskaya ◽  
Aleksandra Olegovna Moskvina
Keyword(s):  
Eating Disorders ◽  
Food Frequency Questionnaire ◽  
Metabolic Disorders ◽  
Risk Group ◽  
Orthorexia Nervosa ◽  
Food Frequency ◽  
Significance Level ◽  
Average Value ◽  
High Prevalence ◽  
Medical University

Today eating disorders and metabolic disorders are increasingly observed among the adult and children’s population. One of the ways to prevent these pathologies is the timely detection and correction of prenosological forms, one of them is orthorexia neurosa. The aim of our study was to identify the prevalence and characteristics of the manifestation of orthorexia nervosa (ON) among students. A survey was conducted among 60 students of a medical university with the «ORTO-15» and the «Food Frequency Questionnaire questionnaires» to obtain the necessary data. We took into account the height and weight of students and calculated body mass index (BMI) according to the Kettle’s formula. The results were statistically processed and calculated the average value (M), the deviation from the average (m). The correlation dependence between the values was estimated by the nonparametric Spearman’s coefficient (p). The data were considered statistically significant at p < 0.05 and a significance level of at least 95 %. The study showed a high prevalence of orthorexia nervosa among the examined individuals (in 80 % of cases, signs of ON were determined). The average BMI was 24.35 ± 5.3 among men and 20.9 ± 4.7 among girls. The normal BMI values among men were determined reliably more often than among girls (p˂0.05). In this case, a correlation between the values of BMI and the severity of signs of orthorexia nervosa was not found among students. According to the results of the «Food Frequency Questionnaire», a significant concern was identified with nutrition issues, both among girls and men. The above allowed us to conclude that the subjects examined constituted a risk group for the formation of mental disorders and eating disorders.

Endocrine and metabolic disorders

2010 ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Disorders ◽  
Endocrine System ◽  
Childhood And Adolescence ◽  
Tall Stature ◽  
Maturity Onset Diabetes ◽  
Anatomy And Physiology ◽  
P Type

The endocrine system: related anatomy and physiology 632Type 1 diabetes mellitus in childhood and adolescence 634Diabetic ketoacidosis (DKA) 636Management of DKA 638Type 2 diabetes mellitus 640Maturity-onset diabetes mellitus of the young (MODY) 642Hypothyroidism 644Short stature 646Tall stature ...

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