scholarly journals A study on comparison of serum creatinine, serum uric acid and serum zinc levels in hypothyroid and healthy controls-at a tertiary care hospital

2019 ◽  
Vol 3 (2) ◽  
pp. 18-20
Author(s):  
Dr. G Ravi Kumar ◽  
Dr. DVS Priyadarshini
Keyword(s):  
Uric Acid ◽  
Serum Creatinine ◽  
Serum Uric Acid ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Serum Zinc ◽  
Care Hospital ◽  
Healthy Controls ◽  
Zinc Levels ◽  
Serum Zinc Levels

scholarly journals Serum Zinc Status in Post Menopausal Women Attending in a Tertiary Care Hospital of Bangladesh

2019 ◽  
Vol 9 (2) ◽  
pp. 147-150
Author(s):  
Nadia Ferdous ◽  
Farzana Akonjee Mishu ◽  
Shamsunnahar ◽  
Fahmida Islam ◽  
Shabnam Sarwar Sejooti
Keyword(s):  
Clinical Symptoms ◽  
Tertiary Care ◽  
Serum Zinc ◽  
Premenopausal Women ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College ◽  
Significant Difference ◽  
Zinc Levels ◽  
Serum Zinc Levels

Background: Nutritional needs change throughout the various stages of life. While overall caloric needs tend to decrease with age, the requirements for individual micronutrients do not decrease. In fact, the needs for some micronutrients actually increase with age. The risk of nutritional disturbances mainly trace elements deficiencies is high during postmenopause causing or intensifying serious clinical symptoms. Methods: This cross-sectional study was carried out in the Department of Biochemistry, Mymensingh Medical College in collaboration with the Department of Obstetrics and Gynecology , Mymensingh Medical College Hospital during the period from July 2013 to June 2014. A total of 100 subjects were included in this study. Among them 50 apperantly healthy postmenopausal womenaged between 45-70 years were considered as case and another 50 regular menstruating premenopausal women aged between 30-40 years were selected as control. Results: The mean age of case and control groups was 50.5± 2.3 years and 36.5± 4.4 years respectively. In this study serum zinc levels in cases and controls were 71.54 ± 5.69 ìg /dl and 74.68 ± 5.453 ìg/dl respectively, and there was significant difference(p<0.01). Conclusion: Serum zinc level was significantly decreased in postmenopausal group in comparison to premenopausal women (p< 0.01). Estimation of serum zinc levels might be incorporated in every postmenopausal for possible prevention of complications. Birdem Med J 2019; 9(2): 147-150

scholarly journals Uric Acid Abnormalities and Its Correlation with Splenectomy in Adult Transfusion Dependent Thalassemia Subjects (TDT)

2021 ◽  
Vol 8 (5) ◽  
Author(s):  
Sahithi A ◽  
◽  
Aggarwal R ◽  
Prakash A ◽  
Jain SK ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Creatinine ◽  
Serum Uric Acid ◽  
Turnover Rate ◽  
Tertiary Care ◽  
Significant Risk ◽  
Tubular Dysfunction ◽  
Renal Tubules ◽  
Care Hospital ◽  
Cross Sectional

Background: In thalassemia patients erythrocyte turnover rate increases due to chronic hemolysis and ineffective erythropoiesis leading to increase in uric acid production. Hyperuricosuria is one of the marker of proximal tubular dysfunction. Splenectomy can increase the risk of hyperuricemia by increasing erythrocyte turnover rate in Transfusion Dependent Thalassemia (TDT). Deferasirox enhances uric acid excretion from renal tubules leading to low serum uric acid levels. Methods: An institution based cross-sectional study was conducted from November 2018-March 2020 which included 60 adult TDT patients (≥18 years) attending Adult Thalassemia Day Care Centre at tertiary care hospital. Serum uric acid (mg/dl), 24 hour urinary uric acid (mg/dl), serum ferritin (ng/ml) were done. Results: Hyperuricemia was present in 20%, hypouricemia in 3.33%. Hyperuricosuria was present in 80%. Mean SUA levels were higher in males than females which was statistically significant (5.77±1.66 vs 4.64±1.44, p=0.007). There was statistically significant positive correlation between serum uric acid and serum creatinine(p = 0.0036) and age (p=0.0129). Hyperuricemia was more in subjects with intact spleen but was not statistically significant(p=0.104). Hyperuricemia had negative association with deferasirox therapy [1 (3.03%) vs 11 (40.74%), p=0.0004] compared with normouricemia subjects. Conclusion: Uric acid abnormalities were seen in 23.3% of patients. Hyperuricemia was present in one fourth of the patients and significant risk factors were increasing age, male gender, rising serum creatinine. Deferasirox therapy was negatively associated with hyperuricemia. Tubular dysfunction is relatively common in TDT as more than three fourth patients had hyperuricosuria. Regular monitoring of serum uric acid and urinary uric acid is recommended.

EVALUATION OF SERUM URIC ACID AND ITS CORRELATION IN YOUNG NEWLY DIAGNOSED ESSENTIAL HYPERTENSIVES

2021 ◽  
pp. 65-66
Author(s):  
Atindra Narayan ◽  
Kuber Sharma ◽  
D.K. Sharma
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Newly Diagnosed ◽  
Blood Pressures ◽  
Public Health Challenge ◽  
Prognostic Importance ◽  
Control Study

Background: Hypertension is a major public health challenge and is the third leading killer in the World. The serum uric acid has shown some prognostic importance in essential hypertension Methodology: Acase control study was undertaken in a tertiary care hospital in Gurugram. Seventy ve cases of hypertension and equal number of controls were studied for the hypertension and serum uric acid levels. Results:This study had shown that, majority of the cases and controls were aged 31 – 40 years and females. The blood pressures were signicantly more in the cases than controls. Serum uric acid levels were also signicantly higher in cases than controls. There was no statistically signicant difference in serum uric acid levels between different stages of hypertension. Conclusion:The serum uric acid levels were signicantly higher in cases of hypertension than controls.

scholarly journals FEBRILE SEIZURES

2018 ◽  
Vol 25 (03) ◽  
pp. 461-465
Author(s):  
Nathumal Maheshwari ◽  
Om Perkash ◽  
Mehmood Shaikh ◽  
Bilawal Hingorjo ◽  
Yasmeen Kazi ◽  
...  
Keyword(s):  
Venous Blood ◽  
Tertiary Care ◽  
Serum Zinc ◽  
Febrile Seizures ◽  
P Value ◽  
Care Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Zinc Levels ◽  
Serum Zinc Levels

Objectives: To determine the serum zinc levels in children with simple febrileseizures reporting at a tertiary care hospital of Sindh. Study Design: Cross sectional study.Place and Duration: Department of Paediatrics, Layari General Hospital Shaheed MuhtramaBenazir Bhutto Medical College from January 2015 to February 2016. Methodology: A sampleof 120 children (60 cases and 60 controls) was selected through non- probability (purposivesampling) by pre defined inclusion and exclusion criteria. 3 ml venous blood was taken from aperipheral vein. Blood was process, centrifuged and sera were used for the analysis of serumzinc. Data of cases and controls was analyzed on Statistix 10.0 software (USA). P-value of≤0.05 was considered statistically significant. Results: Age of controls and cases was notedas 13.68±8.74 and 15.75±9.11 months respectively and most common age group was 12 - 24months in the cases. Male children predominated. Means± SD serum zinc was 79.03±24.17and 62.82±14.66 in controls and cases respectively (P=0.0001). Low serum zinc was noted in66.6% of cases compared to 40% in controls (P=0.0001). Conclusion: We noted low serumzinc levels in children with febrile seizures which may provoke febrile seizures. Children with lowserum zinc levels are prone to febrile seizures. 

scholarly journals A study of serum zinc levels in children admitted with pneumonia in a tertiary care hospital in India

2022 ◽  
Vol 8 (12) ◽  
pp. 426-429
Author(s):  
Ashrin A Naushad ◽  
Ashrin A Naushad ◽  
Lalitha Kailas ◽  
Sreekanth K Sivaraman
Keyword(s):  
Risk Factors ◽  
Tertiary Care ◽  
Serum Zinc ◽  
Nutritional Risk ◽  
World Health ◽  
Control Group ◽  
Care Hospital ◽  
Age Group ◽  
Zinc Levels ◽  
Serum Zinc Levels

Background: Worldwide, pneumonia is a leading cause of morbidity and mortality in children under 5 years of age; especially, in developing countries. Objectives: The objective of the study is to investigate whether zinc deficiency and other nutritional factors are related to pneumonia in children between 6 months and 5 years old. Methodology: In this casecontrol study, a valid written consent was obtained from mothers of enrolled children. The cases included 75 children fulfilling the World Health Organization criteria for pneumonia, between the age group of 6 months and 5 years. They were interrogated for potential nutritional risk factors as per a predesigned proforma followed by a measurement of serum zinc levels. In the control group, 75 children of the same age group who were siblings of admitted children were included along with other children of the same age group admitted for non-respiratory complaints. A detailed case history was obtained and physical examination was done according to a predesigned proforma to elicit various potential risk factors. A semi-auto analyzer was used to measure the serum zinc levels through colorimetric methods using 5-bromo-PAS. Results: Significant nutritional risk factors identified were low serum zinc level, malnutrition, and anemia. Conclusion: The present study has identified various nutritional risk factors for pneumonia which can be tackled through effective education of the community and appropriate initiatives.

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