scholarly journals Thermography of periodontal tissues in patients with partial tooth loss before and after orthopedic treatment

2020 ◽  
pp. 22-24
Author(s):  
E. N. Zhulev ◽  
E. P. Arkhangelskaya

The article is devoted to the study of the condition of periodontal tissues in patients with diagnoses of ‘defect of hard tissue of teeth’ and ‘partial loss of teeth’ before and after orthopedic treatment using the method of thermography. The method of infrared thermography has such qualities as high information content, non-invasive research, ease of use, objectivity and complete safety. 50 patients were examined before and after prosthetics with fixed prostheses and 30 subjects of the control group with an intact periodontium. As a result of the study, data were obtained that led to the conclusion that orthopedic treatment of patients with periodontal diseases favorably affects the state of periodontal tissues, reducing inflammation, as evidenced by a decrease in thermography values after treatment.

2021 ◽  
pp. 59-63
Author(s):  
О.V. Bida ◽  
О.V. Bida

Resume. According to epidemiological studies, there is still an increased prevalence of periodontal disease among the population of different regions of the world, with increasing intensity and aggressiveness. Long-term chronic generalized lesions of recurrent and progressive inflammatory-dystrophic process lead to the destruction of alveolar processes, pathological mobility of teeth, tooth loss and dentofacial dysfunctions. One of the most characteristic symptoms of generalized periodontitis is the presence of traumatic occlusion. Depending on the degree of pathological changes in periodontal tissues, the size and topography of dentition defects, the replacement of dentition pathologies should be planned by splint-type orthopedic structures and computerized analysis of occlusal relationships with T-Scan III system. The aim of the study is to improve the effectiveness of orthopedic treatment of periodontal diseases complicated by defects of the dentition with the control of occlusal relationships with a computerized T-Scan III system. Materials and methods. We have examined 87 persons aged between 30 and 69 years with generalized periodontitis of I – III severity, complicated by partial loss of teeth of different sizes and topography, and a control group of the same age in 10 patients with intact dentition and physiological forms of occlusion without clinically diagnosed periodontal diseases. Computerized analysis of occlusion indices was performed by the T-Scan III system. We have investigated the stereotype of functional loads according to the following quantitative and qualitative indicators: the index of asymmetry of force between the parts (%); time of occurrence of the maximum amount of dental contacts (sec); time of disclusion (sec); the presence of premature occlusal contacts on the natural teeth and orthopedic constructions, and the presence of changes in the direction of the trajectory of the total vector of occlusal load.  Orthopedic rehabilitation of patients in the case of periodontal diseases of the I-II degree of severity and the presence of small defects of the dentition, we conducted by splint-type orthopedic structures, dental implants, and artificial crowns of our own design with discrete occlusal loading (Licence for Effective Model No 143278, Ukraine, MPK А61С 13/007, u 2019 11487: Artificial Crown with Support on a Dental Implant). Patients with periodontal diseases of the II – III severity, complicated by defects of dentitions with different size and topography, the dental prosthetics has been performed by traditional removable and combined orthopedic splint-type constructions, and removable splint-type dentures of their own design: "Removable Prosthesis of Splint Type" (Licence for Effective Model No 130980 Ukraine, IPC (2006.01) А61С 13/007, u 2018 03039, 10.01.2019).  Computerized analysis of occlusion indicators for the patients of I and II clinical groups and the III control group has been performed before and after orthopedic treatment by T-Scan III system. Results of the research. The results of investigation for functional occlusion have demonstrated that the index of relative strength asymmetry between the sides of the dentition in patients with generalized periodontitis complicated by dentition defects increased significantly and led to nonphysiological redistribution of loads compared with indices obtained in patients from control group due to the lack of correspondence for occlusal contacts. These indices are equal to 16.7 ± 3.8% in patients of I group and 18.9 ± 4.8% in group II compared to the similar control indicators – 4.7 ± 1.01%, respectively (p≤0.01). It should be noted that these indicators have differed from the control group indicators according to the severity of the pathological process. Rational prosthetics with removable and non-removable orthopedic structures, including on the base of dental implants, helps to optimize occlusal relations. Conclusions. Occlusographic studies performed in patients with generalized periodontitis having different severity and complicated by partial tooth loss have showed increased index of relative strength asymmetry between the sides of chewing, the presence of premature contacts and incorrect location of the trajectory of the total occlusal load vector. The dynamics of pathological changes in occlusion indices corresponds to the degree of generalized periodontitis, which indicates the necessity of opportune replacement of dentition defects, taking into account the occlusal relations. Rational prosthetics helps to optimize occlusal relations.


Pteridines ◽  
2003 ◽  
Vol 14 (3) ◽  
pp. 77-81 ◽  
Author(s):  
Aysen Bodur ◽  
Terken Baydar ◽  
Nurdan Ozmeric ◽  
Ayse Basak Engin ◽  
Ahu Uraz ◽  
...  

Abstract Periodontal disease results from the interaction of the host defence mechanisms with the microbial dental plaque. Analysis of gingival crevicular Huid (GCF) provides a non-invasive means of evaluating the role of the host response in periodontal disease. Based on our previous study, demonstrating increased levels of neopterin in GCF and saliva from patients with aggressive periodontitis (AgP), the aim of this study was to evaluate the effect of periodontal treatment on the levels of neopterin in GCF, saliva and urine of patients with AgP.Pre-treatment values of neopterin in GCF were 4.04 ± 0.86 nmol/ml for the AgP group (n=8) and 2.68 ± 0.90 nmol/ml fyr the control group (n=8; difference not significant). After periodontal treatment, the level of ncoptei in was found 2.38 ± 0.72 nmol/ml in the patient group which did not differ f r om pre-treatment levels. The salivary neopterin concentration was higher in both AgP groups (14.14 ± 2.85 nmol/1 and 8.02 ± 3.12 nmol/1, before and after periodontal treatment) than in controls (2.58 ± 0.3 nmol/1; both p<0.05). No significant difference in salivary neopterin level was observed in patients before and after periodontal treatment.Concentrations of urine neopterin in patients before treatment were 188.5 ± 30.98 μηιοί neopterin/mol creatinine and 168.1 + 20.21 μηιοί in controls (difference not significant). Following periodontal treatment, the urinary neopterin levels (310.1 ± 39.82 μηιοί neopterin/mol creatinine) were higher when compared to the baseline levels and to controls (p<0.05).Our results suggest that neopterin in saliva and GCF might be associated with the periodontal diseases process.


Author(s):  
Iskander I. Zaidullin ◽  
Denis O. Karimov ◽  
Lilija K. Karimova ◽  
Milyausha F. Kabirova ◽  
Rasima R. Galimova ◽  
...  

The susceptibility to the development and progression of inflammatory periodontal diseases, which depends on genetic and external factors (smoking, stress, oral hygiene), varies widely. In the development of these diseases, an important role is played not only by the presence of periodontal pathogenic microorganisms, but also by the presence of congenital or acquired immunodeficiency, immunoregulatory defects. The immune system plays a key role in the physiological and pathological processes of periodontal tissues. In this regard, IL17, produced by CD4+ Th cells, which has both Pro-inflammatory and protective activity, is of particular interest in the pathogenesis of periodontitis. The aim of study was to identify the relationship between polymorphic loci of the IL-17A (rs2275913) and MMP-1 (rs1799750) genes and clinical manifestations of chronic periodontitis in petrochemical workers. Dental examination was performed in 92 ethylene oxide production workers with chronic periodontitis and 74 patients with chronic periodontitis who did not come into contact with chemical factors (control group). Genotyping of polymorphisms rs2275913 of the IL17A gene and rs1799750 of the MMP1 gene was performed by allele-specific real-time polymerase chain reaction (PCR). Hygienic assessment of the degree of air pollution of the working area with harmful substances was carried out by gas chromatography according to the guidelines for the determination of harmful substances in the air № 5098-89, № 3119-84. When comparing the results of studies of both groups, there were no statistically significant differences in the frequency distributions of allelic variants and genotypes of the IL-17A and MMP-1 genes. The AA/AG genotypes of the IL-17A gene were associated with an increased risk of severe disease compared to the GG genotype in workers in the main group (OR=6.1; 95% CI 1.33-28.5; p=0.021) and in the control group (OR=7.26; 95% CI 1.34-39.25; p=0.016). Carriers of the A allele in the control group increased the risk of severe chronic periodontitis by 2.4 times compared to carriers of the G allele (OR=2.41; 95% CI 1.19-4.87; p=0.014). During the dental examination of employees of the ethylene oxide plant, the clinical course of periodontal diseases was more severe in comparison with the control group, and the number of patients with severe periodontitis was twice as high. It was found that the AA/AG genotypes of the IL-17A gene and the carrier of the A allele are associated with increased susceptibility to the development of severe chronic periodontitis. The association between the MMP-1 gene polymorphism and the risk of severe forms of chronic periodontitis has not been established. A risk factor for the development of inflammatory periodontal diseases in employees of the petrochemical complex is a complex of harmful production factors.


2021 ◽  
Vol 27 (1-2) ◽  
pp. 46-62
Author(s):  
A.G. Oliynyk ◽  

Aim. The study aims at enhancing the therapeutic effect and reducing the duration of treatment by using a solution of titanium dioxide in ozonated distilled water for antiseptic treatment of periodontal tissues. Material and Methods. Treatment results of local inflammatory changes of periodontal tissues in 128 patients (73 female, 55 male aged 21-65 years) were analyzed and classified by the severity of periodontal disease as: gingivitis, primary and moderate periodontitis. Schemes of medical actions differed in pharmacotherapy. In order to ascertain the most effective approach, the results of conventional and developed treatment complexes were compared. Results and Discussion. Digital indicators of the periodontal tissues condition following treatment presented common positive dynamic in all patients. However, significantly better results were obtained by using the developed method. According to the dynamics of bleeding index values, the proposed treatment regimens allow achieving more effective control over the inflammatory process. Digital indicators of hygiene showed that a better effect was reached after the suggested method - the dynamics of reducing the depth of periodontal pockets demonstrated clearer and statistically better results. Changes in the pH of the gingival fluid in a severe inflammatory condition indicated a considerable improvement after using the suggested treating method. X-ray data demonstrated the stability of digital values in the observation groups before and after treatment, which was interpreted as a sufficient control of destructive processes. Conclusion. Mathematical analysis of the presented data demonstrates the benefits of the developed method for the treatment of periodontal diseases, especially in non-surgical treatment regimens. The performed research confirms greater effectiveness of the therapeutic method in initial lesions, and thus it proves the efficiency of complex control for preventive purposes


Author(s):  
Ramida Vaqif qizi Shadlinskaya ◽  
E. K Gasimov ◽  
S. A Israfilova

Introduction: β-thalassemia major is a hereditary blood disease, a main pathogenetic factor of which is the disruption of the synthesis of β-chains of hemoglobin. Inevitable metabolic disorders that occur during regular blood transfusion form an additional risk of damage and cellular modification of organs and tissues, including the oral cavity. Aim: determination of the pathogenetic role of iron metabolism disorder in the development of chronic inflammatory periodontal diseases in patients with β-thalassemia. Material and methods: 12 patients with β - thalassemia major who had periodontal diseases were examined in the Republican Center of Thalassemia in Baku (average age is 18 ± 1.3 years). The control group consisted of 16 somatically healthy individuals with intact gingiva tissues (the average age is 18.0 ± 0.7 years). Serum Iron, ferritin, hepcidin, total iron-binding capacity (TIBC), level of Il2, Il6, Il10, TNFα were measured from peripheral blood samples. To determine the ultra-structural study of the periodontal tissues in patients with β-thalassemia major, the method of electron microscopy studies of gingiva biopsies was used. Results of the study: The study revealed an increase in the level of serum iron and ferritin against the background of a progressively decreasing TIBC in patients with β-thalassemia major. Also activation of pro-inflammatory cytokines - TNFα, Il6, Il10 was observed in homozygous patients. Metabolic indicators are compared with ultrastructural features of cellular elements of a gum. Signs of accumulation of iron in cellular elements both of its own plate and of the epithelial cover were compared. The presence of iron was recorded in immunocompetent cells - macrophages and lymphocytes. Conclusion: Summarizing the data obtained, we can conclude that deproteinization of ferritin cores and their detection both in the cytoplasm and in the nucleoplasm of immunocompotent cells leads to irreversible degenerative changes in cellular elements of the gingiva. The authors link the development of the generalized inflammatory - degenerative process in the periodontium with revealed exchange -structural violations.


2019 ◽  
Vol 70 (11) ◽  
pp. 4068-4072
Author(s):  
Andra Aungurencei ◽  
Ionut Luchian ◽  
Ancuta Goriuc ◽  
Dana Constantinescu ◽  
Ioana Martu ◽  
...  

Periodontal diseases ranges from simple gum inflammation to serious disease that consists in major damage to the soft tissue and bone teeth support. Periodontal diseases affects the marginal and apical periodontium and results from the interaction between bacterial biofilm and the host response. To determine the concentrations of MMP-8, as a disease marker, in saliva in prosthetic and nonprosthetic, aggressive (AP) and chronic (CP) periodontitis, doxycycline treated patients. 40 patients were distributed into 3 groups: 12 diagnosed with aggressive (AgP), 18 with chronic (CP) periodontitis. Each of these groups was subdivided into 2 subgroups with and without fixed prosthesis. 10 patients were in the normal group. Matrix metalloproteinase 8 (MMP-8) was evaluated before and after systemic doxycycline (Dox) treatment. mean MMP-8 value into the control group was 0.57 ng/mL with a standard deviation (STD) of 0,094 ng/mL. Highest MMP-8 value was established for the nonprosthesis AgP subgroup, before Dox treatment. The highest reduction in MMP-8 levels (40.8%) was between nonprosthesis AgP before Dox treatment and the same group after Doxycycline treamtent. MMP-8 saliva levels are lower than GCF levels, mostly through a dilution mechanism as previous studies had shown. Our study revealed that saliva MMP-8 level is relible marker for AgP but not for CP. Doxycycline treatment, in terms of lowering MMP-8 levels is most effective in patients that have AP and are also wearing fixed.


2020 ◽  
Vol 9 (1) ◽  
pp. 784-788

Periodontitis is a chronic inflammatory disease of the vascularized supporting tissues of the teeth. Angiogenesis (neovascularization) is the budding of new capillaries and is thought to be an essential process in the development of chronic inflammatory diseases. Inflamed tissues (such as gingiva coincident in periodontal disease) have evidence of enhanced expression of inflammatory mediators, many of which can promote angiogenesis. Of the various cytokines and growth factors that are involved in angiogenesis, the most potent agent that acts specifically on vascular epithelium is Vascular Endothelial Growth Factor. Even though angiogenesis is a prominent feature of both inflammation and healing, information about its role in periodontal lesions is limited. Hence the aim of the present study was the immunohistochemical evaluation of the expression of VEGF in the gingival tissues of chronic and aggressive periodontitis patients compared to the healthy controls. The present study was carried out in a total of 45 subjects with age range of 18-55 years, reporting to the Department of Periodontology, Rajarajeswari Dental College and Hospital, Bangalore. Gingival tissue samples were collected from all the 45 subjects and categorized into three groups based on their clinical findings as follows: Group 1 (Healthy), Group II (Chronic Periodontitis), Group III (Aggressive Periodontitis). Following sample collection, immunohistochemical staining of tissues was carried out and evaluation was done to compare the grades of expression of VEGF in the three groups. The expression of VEGF in blood vessels was also quantitatively evaluated. The results were statistically analyzed using Kruskal Wallis ANOVA and Mann Whitney test. There was a statistically significant higher expression of VEGF in both chronic periodontitis and aggressive periodontitis group as compared to the control group. Aggressive periodontitis cases showed higher grades of expression of VEGF compared to the chronic periodontitis cases and healthy controls. However, the difference in expression of VEGF was not statistically significant between the two forms of periodontitis. The presence of VEGF in both chronic and aggressive periodontitis clearly indicates the potent role played by VEGF as an inflammatory agent in the initiation and progression of periodontal diseases. Thus, VEGF might be used as a potential vascular marker for the assessment of severity and inflammatory status in periodontal disease.


Author(s):  
Shole Vatanparasti ◽  
◽  
Anoshirvan Kazemnejad ◽  
Shahram Oveisgharan ◽  
◽  
...  

Introduction: This study aimed to investigate the influence of neglect and the effect of Prism Adaptation (PA) combined with continuous Theta-Burst Transcranial Magnetic Stimulation (cTBS) on the art constructive errors of painting rehabilitation of stroke patients with neglect. Methods: Fourteen patients with neglect and art constructive errors of painting secondary to stroke were randomly assigned to the rehabilitation group and received PA combined with inhibitory protocol of cTBS over the intact parietal cortex; the control group received PA combined with sham cTBS for 2 weeks in 10 daily sessions. Patients have assessed for art constructive errors of painting in Figure Copying Test (FCT), and Coloring Test (CT) before and after the intervention. Art constructive errors of painting were classified into omission, deformation, size, neglect of warm colors, and perseveration of errors. Neglect was evaluated using the Line Bisection task (LBT), Figure Copying Test (FCT), and Coloring Test (CT). Results: All patients showed significant improvement in art constructive errors of painting (measured using pattern of painting’ errors in Figure Copying Test and Coloring Test), and neglect (measured using LBT, FCT, and CT) (p<0.05). Omission, neglect of warm colors, and deformation were the most frequent errors. Conclusion: Neglect and rehabilitation influences the painting system in stroke patients. Both approaches improved art constructive errors of painting and neglect symptoms.


2016 ◽  
Vol 12 (1) ◽  
pp. 85-89
Author(s):  
Ф. Маннанова ◽  
F. Mannanova ◽  
Т. Ганеев ◽  
T. Ganeev ◽  
И. Исхаков ◽  
...  

<p>The authors describe two clinical cases with sophisticated prosthetics defects dentition with allceramic. Of complications (increased abrasion, deformation of dentition, reduces occlusion) after tooth extraction complicated rational prosthesis. It took a phased prosthesis with a preparatory phase. Failure to do so can lead to complications and aesthetic dissatisfaction of patients from the orthopedic treatment results.</p><p>The deformations of dentition occur when the full or partial destruction of the crowns of teeth, dentition defect with partial loss, periodontal diseases, tumors and other pathological conditions that lead to a change in the position of teeth (sagittal, vertical and transversal) of the three mutually perpendicular planes.</p><p>The appearance of defects violates not only the morphological unity of the dentition, but also leads to its complex restructuring, first appearing near the defect, and then extended to the entire dentition and the entire dentition system. Outwardly, this restructuring is manifested teeth tilt toward the defect, the vertical movement of the teeth, deprived of antagonists, their inclination mainly in the lingual side, rotating around an axis.</p><p>Shifting teeth leads eventually to a more or less pronounced disturbance of the occlusal surface of the dentition, lower occlusal height complicating clinic partial loss of teeth, making it difficult to conduct a rational choice and orthopedic treatment.</p>


2019 ◽  
Vol 15 (3) ◽  
pp. 96-102
Author(s):  
Петрос Нерсесян ◽  
Petros Nersesyan ◽  
Сергей Жолудев ◽  
Sergey Zholudev ◽  
Владимир Базарный ◽  
...  

Subject. To improve the effectiveness of prosthetics for tooth loss, an abutment is proposed, which is used both as an artificial crown and a gum former, which is especially important for prosthetics in the frontal group of teeth. An analysis was made of the local content of matrix metalloproteinases (MMP) 8 and 9 and their tissue inhibitor (TIMP) and buccal cytology in patients before and after dental implantation surgery using the author's technique and the traditional protocol. Objective ― to evaluate the effectiveness and non-invasiveness of using the author’s abutment design under immediate loading by evaluating oral homeostasis and the level of cell proliferation. Methodology. Three groups of patients were examined: the main of 25 patients from 30 to 60 years old, who used the original technique, comparisons - 40 patients of the same age, where prosthetics and implantation were performed according to the traditional two-stage protocol and a control group of 40 somatically preserved patients of the same age, which do not require dental prosthetics. In all groups, MPP 8, 9, TIMP were studied, and the buccal cytology was also evaluated. Results. The pathogenetic role of disorders of the connective tissue matrix in the development of early complications of dental implantation was revealed. Findings: Laboratory studies and clinical observations of patients of the main group and the comparison group indicate the effectiveness and non-invasiveness of the original methods of prosthetics on implants using an individual abutment with a gingiva shaper.


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