Active Whale Avoidance by Large Ships: Components and Constraints of a Complementary Approach to Reducing Ship Strike Risk

This article presents a description of Art of Invitation as a complementary approach to traditional addiction treatment through the alignment of Art of Invitation (AOI) with Substance Abuse and Mental Health Services Administration (SAMHSA) Ten Guiding Principles for Recovery. AOI is a faith based relationship building approach that combines key Judeo/Christian teachings with relationship building tools, skills, and concepts for those seeking to build and restore relationships. SAMHSA, as the leading agency within the U.S. Department of Health and Human Services, spearheads public health efforts to advance behavioral health within the United States. Each Guiding Principle is presented along with a description of how AOI is shared with incarcerated women, an often neglected population, participating in an inpatient treatment program housed in a community corrections facility.

Download Full-text

Preparing for War

10.1093/oso/9780198805199.003.0005 ◽

2017 ◽

Author(s):

David G. Morgan-Owen

Keyword(s):

Grand Strategy ◽

Military Policy ◽

Complementary Approach ◽

Regular Army ◽

Political Intervention ◽

The Government

The period 1904–6 proved to be a fateful one for the CID. The government successfully divorced the Regular Army from its defensive duties and re-orientated it towards operations overseas—the necessary first step to producing a more coherent, complementary approach to imperial defence. Yet despite this change in military policy, the CID failed to become a forum in which the two services could debate and co-operate in the interests of producing a cohesive grand strategy. Political intervention thus merely changed the parameters within which quasi-independent naval and military strategies continued to compete, intersect, and diverge—to the detriment of overall British readiness for war.

Download Full-text

Sarcopenia and Malnutrition Screening in Female Osteoporosis Patients—A Cross-Sectional Study

Journal of Clinical Medicine ◽

10.3390/jcm10112344 ◽

2021 ◽

Vol 10 (11) ◽

pp. 2344

Author(s):

Franca Genest ◽

Dominik Rak ◽

Elisa Bätz ◽

Kerstin Ott ◽

Lothar Seefried

Keyword(s):

At Risk ◽

Risk Groups ◽

Cross Sectional Study ◽

Mineral Density ◽

Cross Sectional ◽

Functional Deficits ◽

Complementary Approach ◽

Study Results ◽

Patients At Risk ◽

Not At Risk

Sarcopenia and malnutrition are important determinants of increased fracture risk in osteoporosis. SARC-F and MNA-SF are well-established questionnaires for identifying patients at risk for these conditions. We sought to evaluate the feasibility and potential added benefit of such assessments as well as the actual prevalence of these conditions in osteoporosis patients. We conducted a cross-sectional, single-center study in female osteoporosis patients ≥ 65 years (SaNSiBaR-study). Results of the sarcopenia (SARC-F) and malnutrition (MNA-SF) screening questionnaires were matched with a functional assessment for sarcopenia and data from patients’ medical records. Out of 107 patients included in the analysis, a risk for sarcopenia (SARC-F ≥ 4 points) and a risk for malnutrition (MNA-SF ≤ 11 points) was found in 33 (30.8%) and 38 (35.5%) patients, respectively. Diagnostic overlap with coincident indicative findings in both questionnaires was observed in 17 patients (16%). As compared to the respective not-at-risk groups, the mean short physical performance battery (SPPB) score was significantly reduced in both patients at risk for sarcopenia (7.0 vs. 10.9 points, p < 0.001) and patients at risk for malnutrition (8.7 vs. 10.5 points, p = 0.005). Still, confirmed sarcopenia according to EWGSOP2 criteria was present in only 6 (6%) of all 107 patients, with only 3 of them having an indicative SARC-F score. Bone mineral density was not significantly different in any of the at-risk groups at any site. In summary, applying SARC-F and MNA-SF in osteoporosis patients appears to be a complementary approach to identify individuals with functional deficits.

Download Full-text

Endovascular embolization versus surgical clipping in a single surgeon series of basilar artery aneurysms: a complementary approach in the endovascular era

Acta Neurochirurgica ◽

10.1007/s00701-021-04803-5 ◽

2021 ◽

Vol 163 (5) ◽

pp. 1527-1540

Author(s):

Ethan A. Winkler ◽

Anthony Lee ◽

John K. Yue ◽

Kunal P. Raygor ◽

W. Caleb Rutledge ◽

...

Keyword(s):

Basilar Artery ◽

Open Surgery ◽

Endovascular Embolization ◽

Neurologic Outcome ◽

Endovascular Coiling ◽

Surgical Clip ◽

Complementary Approach ◽

Complete Obliteration ◽

Good Neurologic Outcome ◽

Appropriate Therapy

Abstract Background Currently, most basilar artery aneurysms (BAAs) are treated endovascularly. Surgery remains an appropriate therapy for a subset of all intracranial aneurysms. Whether open microsurgery would be required or utilized, and to what extent, for BAAs treated by a surgeon who performs both endovascular and open procedures has not been reported. Methods Retrospective analysis of prospectively maintained, single-surgeon series of BAAs treated with endovascular or open surgery from the first 5 years of practice. Results Forty-two procedures were performed in 34 patients to treat BAAs—including aneurysms arising from basilar artery apex, trunk, and perforators. Unruptured BAAs accounted for 35/42 cases (83.3%), and the mean aneurysm diameter was 8.4 ± 5.4 mm. Endovascular coiling—including stent-assisted coiling—accounted for 26/42 (61.9%) treatments and led to complete obliteration in 76.9% of cases. Four patients in the endovascular cohort required re-treatment. Surgical clip reconstruction accounted for 16/42 (38.1%) treatments and led to complete obliteration in 88.5% of cases. Good neurologic outcome (mRS ≤ 2) was achieved in 88.5% and 75.0% of patients in endovascular and open surgical cohorts, respectively (p = 0.40). Univariate logistic regression analysis demonstrated that advanced age (OR 1.11[95% CI 1.01–1.23]) or peri-procedural adverse event (OR 85.0 [95% CI 6.5–118.9]), but not treatment modality (OR 0.39[95% CI 0.08–2.04]), was the predictor of poor neurologic outcome. Conclusions Complementary implementation of both endovascular and open surgery facilitates individualized treatment planning of BAAs. By leveraging strengths of both techniques, equivalent clinical outcomes and technical proficiency may be achieved with both modalities.

Download Full-text

Mendelian randomisation for psychiatry: how does it work, and what can it tell us?

Molecular Psychiatry ◽

10.1038/s41380-021-01173-3 ◽

2021 ◽

Author(s):

Robyn E. Wootton ◽

Hannah J. Jones ◽

Hannah M. Sallis

Keyword(s):

Risk Factors ◽

Mental Illness ◽

Risk Factor ◽

Low Cost ◽

Sensitivity Analyses ◽

Mendelian Randomisation ◽

Naturally Occurring ◽

Complementary Approach ◽

Randomised Control Trials ◽

Successful Prevention

AbstractThe successful prevention of mental illness relies upon the identification of causal, modifiable risk factors. However, observational evidence exploring such risk factors often produces contradictory results and randomised control trials are often expensive, time-consuming or unethical to conduct. Mendelian randomisation (MR) is a complementary approach that uses naturally occurring genetic variation to identify possible causal effects between a risk factor and an outcome in a time-efficient and low-cost manner. MR utilises genetic variants as instrumental variables for the risk factor of interest. MR studies are becoming more frequent in the field of psychiatry, warranting a reflection upon both the possibilities and the pitfalls. In this Perspective, we consider several limitations of the MR method that are of particular relevance to psychiatry. We also present new MR methods that have exciting applications to questions of mental illness. While we believe that MR can make an important contribution to the field of psychiatry, we also wish to emphasise the importance of clear causal questions, thorough sensitivity analyses, and triangulation with other forms of evidence.

Download Full-text

Scene Wireframes Sketching for Drones

Proceedings ◽

10.3390/proceedings2181193 ◽

2018 ◽

Vol 2 (18) ◽

pp. 1193

Author(s):

Roi Santos ◽

Xose Pardo ◽

Xose Fdez-Vidal

Keyword(s):

State Of The Art ◽

Point Clouds ◽

Outdoor Environment ◽

Point Matching ◽

3D Point Clouds ◽

Complementary Approach ◽

Straight Line ◽

Scene Representation ◽

Feature Point Matching ◽

3D Scene

The increasing use of autonomous UAVs inside buildings and around human-made structures demands new accurate and comprehensive representation of their operation environments. Most of the 3D scene abstraction methods use invariant feature point matching, nevertheless some sparse 3D point clouds do not concisely represent the structure of the environment. Likewise, line clouds constructed by short and redundant segments with inaccurate directions limit the understanding of scenes as those that include environments with poor texture, or whose texture resembles a repetitive pattern. The presented approach is based on observation and representation models using the straight line segments, whose resemble the limits of an urban indoor or outdoor environment. The goal of the work is to get a full method based on the matching of lines that provides a complementary approach to state-of-the-art methods when facing 3D scene representation of poor texture environments for future autonomous UAV.

Download Full-text

LOWER BOUNDS OF CHARACTERISTIC SCALE OF TOPOLOGICAL MODIFICATION OF THE NEWTONIAN GRAVITATION

International Journal of Modern Physics D ◽

10.1142/s0218271812500484 ◽

2012 ◽

Vol 21 (05) ◽

pp. 1250048

Author(s):

L. IORIO

Keyword(s):

Semimajor Axis ◽

Data Sets ◽

Orbital Elements ◽

Dynamical Models ◽

Spatial Direction ◽

Newtonian Gravitation ◽

Complementary Approach ◽

Local Modification

We analytically work out the long-term orbital perturbations induced by the leading order of perturbing potential arising from the local modification of the Newton's inverse square law due to a topology ℝ2 × 𝕊1 with a compactified dimension of radius R recently proposed by Floratos and Leontaris. We neither restrict to any specific spatial direction [Formula: see text] for the asymmetry axis nor to particular orbital configurations of the test particle. Thus, our results are quite general. Nonvanishing long-term variations occur for all the usual osculating Keplerian orbital elements, apart from the semimajor axis which is left unaffected. By using recent improvements in the determination of the orbital motion of Saturn from Cassini data, we preliminarily inferred R ≳ 4-6 kau . As a complementary approach, the putative topological effects should be explicitly modeled and solved-for with a modified version of the ephemerides dynamical models with which the same data sets should be reprocessed.

Download Full-text

Threefold complementary approach to holographic QCD

Physics Letters B ◽

10.1016/j.physletb.2013.12.044 ◽

2014 ◽

Vol 729 ◽

pp. 3-8 ◽

Cited By ~ 65

Author(s):

Stanley J. Brodsky ◽

Guy F. de Téramond ◽

Hans Günter Dosch

Keyword(s):

Complementary Approach ◽

Holographic Qcd

Download Full-text

Effect of Rothia mucilaginosa enzymes on gliadin (gluten) structure, deamidation, and immunogenic epitopes relevant to celiac disease

AJP Gastrointestinal and Liver Physiology ◽

10.1152/ajpgi.00144.2014 ◽

2014 ◽

Vol 307 (8) ◽

pp. G769-G776 ◽

Cited By ~ 14

Author(s):

Na Tian ◽

Guoxian Wei ◽

Detlef Schuppan ◽

Eva J. Helmerhorst

Keyword(s):

Celiac Disease ◽

Tissue Transglutaminase ◽

Mass Difference ◽

Cross Linking ◽

Esi Ms ◽

Rp Hplc ◽

Complementary Approach ◽

Sds Page ◽

Rothia Mucilaginosa ◽

Immunogenic Properties

Rothia mucilaginosa, a natural microbial inhabitant of the oral cavity, cleaves gluten (gliadin) proteins at regions that are resistant to degradation by mammalian enzymes. The aim of this study was to investigate to what extent the R. mucilaginosa cell-associated enzymes abolish gliadin immunogenic properties. Degradation of total gliadins and highly immunogenic gliadin 33-mer or 26-mer peptides was monitored by SDS-PAGE and RP-HPLC, and fragments were sequenced by liquid chromatography and electrospray ionization tandem mass spectrometer (LC-ESI-MS/MS). Peptide deamidation by tissue transglutaminase (TG2), a critical step in rendering the fragments more immunogenic, was assessed by TG2-mediated cross-linking to monodansyl cadaverine (MDC), and by a +1-Da mass difference by LC-ESI-MS. Survival of potential immunogenic gliadin epitopes was determined by use of the R5 antibody-based ELISA. R. mucilaginosa-associated enzymes cleaved gliadins, 33-mer and 26-mer peptides into smaller fragments. TG2-mediated cross-linking showed a perfect inverse relationship with intact 33-mer and 26-mer peptide levels, and major degradation fragments showed a slow rate of MDC cross-linking of 6.18 ± 2.20 AU/min compared with 97.75 ± 10.72 and 84.17 ± 3.25 AU/min for the intact 33-mer and 26-mer, respectively, which was confirmed by reduced TG2-mediated deamidation of the fragments in mass spectrometry. Incubation of gliadins with Rothia cells reduced R5 antibody binding by 20, 82, and 97% after 30 min, 2 h, and 5 h, respectively, which was paralleled by reduced reactivity of enzyme-treated 33-mer and 26-mer peptides in the R5 competitive ELISA. Our broad complementary approach to validate gluten degrading activities qualifies R. mucilaginosa-associated enzymes as promising tools to neutralize T cell immunogenic properties for treatment of celiac disease.

Download Full-text

EIGENVECTOR LOCALIZATION AS A TOOL TO STUDY SMALL COMMUNITIES IN ONLINE SOCIAL NETWORKS

Advances in Complex Systems ◽

10.1142/s0219525910002840 ◽

2010 ◽

Vol 13 (06) ◽

pp. 699-723 ◽

Cited By ~ 6

Author(s):

FRANTIŠEK SLANINA ◽

ZDENĚK KONOPÁSEK

Keyword(s):

Online Social Networks ◽

Large Network ◽

Bipartite Networks ◽

Small Communities ◽

Complementary Approach ◽

Matrix Encoding ◽

The Matrix ◽

Network Modules ◽

Principal Tool ◽

Eigenvector Localization

We present and discuss a mathematical procedure for identification of small "communities" or segments within large bipartite networks. The procedure is based on spectral analysis of the matrix encoding network structure. The principal tool here is localization of eigenvectors of the matrix, by means of which the relevant network segments become visible. We exemplified our approach by analyzing the data related to product reviewing on Amazon.com. We found several segments, a kind of hybrid communities of densely interlinked reviewers and products, which we were able to meaningfully interpret in terms of the type and thematic categorization of reviewed items. The method provides a complementary approach to other ways of community detection, typically aiming at identification of large network modules.

Download Full-text