scholarly journals Non-thermal Plasma Treatment of ESKAPE Pathogens: A Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Vladimír Scholtz ◽  
Eva Vaňková ◽  
Petra Kašparová ◽  
Ramya Premanath ◽  
Iddya Karunasagar ◽  
...  

The acronym ESKAPE refers to a group of bacteria consisting of Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. They are important in human medicine as pathogens that show increasing resistance to commonly used antibiotics; thus, the search for new effective bactericidal agents is still topical. One of the possible alternatives is the use of non-thermal plasma (NTP), a partially ionized gas with the energy stored particularly in the free electrons, which has antimicrobial and anti-biofilm effects. Its mechanism of action includes the formation of pores in the bacterial membranes; therefore, resistance toward it is not developed. This paper focuses on the current overview of literature describing the use of NTP as a new promising tool against ESKAPE bacteria, both in planktonic and biofilm forms. Thus, it points to the fact that NTP treatment can be used for the decontamination of different types of liquids, medical materials, and devices or even surfaces used in various industries. In summary, the use of diverse experimental setups leads to very different efficiencies in inactivation. However, Gram-positive bacteria appear less susceptible compared to Gram-negative ones, in general.

Nanomaterials ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 98 ◽  
Author(s):  
Nagendra Kaushik ◽  
Neha Kaushik ◽  
Nguyen Linh ◽  
Bhagirath Ghimire ◽  
Anchalee Pengkit ◽  
...  

Application of plasma medicine has been actively explored during last several years. Treating every type of cancer remains a difficult task for medical personnel due to the wide variety of cancer cell selectivity. Research in advanced plasma physics has led to the development of different types of non-thermal plasma devices, such as plasma jets, and dielectric barrier discharges. Non-thermal plasma generates many charged particles and reactive species when brought into contact with biological samples. The main constituents include reactive nitrogen species, reactive oxygen species, and plasma ultra-violets. These species can be applied to synthesize biologically important nanomaterials or can be used with nanomaterials for various kinds of biomedical applications to improve human health. This review reports recent updates on plasma-based synthesis of biologically important nanomaterials and synergy of plasma with nanomaterials for various kind of biological applications.


Molecules ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 238
Author(s):  
Josef Khun ◽  
Anna Machková ◽  
Petra Kašparová ◽  
Myron Klenivskyi ◽  
Eva Vaňková ◽  
...  

A non-thermal plasma (NTP) is a promising tool against the development of bacterial, viral, and fungal diseases. The recently revealed development of microbial resistance to traditional drugs has increased interest in the use of NTPs. We have studied and compared the physical and microbicidal properties of two types of NTP sources based on a cometary discharge in the point-to-point electrode configuration and a corona discharge in the point-to-ring electrode configuration. The electrical and emission properties of both discharges are reported. The microbicidal effect of NTP sources was tested on three strains of the bacterium Staphylococcus aureus (including the methicillin-resistant strain), the bacterium Pseudomonas aeruginosa, the yeast Candida albicans, and the micromycete Trichophyton interdigitale. In general, the cometary discharge is a less stable source of NTP and mostly forms smaller but more rapidly emerging inhibition zones on agar plates. Due to the point-to-ring electrode configuration, the second type of discharge has higher stability and provides larger affected but often not completely inhibited zones. However, after 60 min of exposure, the NTP sources based on the cometary and point-to-ring discharges showed a similar microbicidal effect for bacteria and an individual effect for microscopic fungi.


1996 ◽  
Vol 1 (1) ◽  
Author(s):  
Mark C. Hsiao ◽  
Bernard T. Merritt ◽  
Bernie M. Penetrante ◽  
George E. Vogtlin ◽  
P. Henrik Wallman ◽  
...  

AbstractNon-thermal plasma processing is an innovative technique for pollutant abatement. This approach involves the use of electrical energy for the production of free radicals which then react with the pollutant molecules. We have studied the oxidation of propene as a prototype hydrocarbon using a packed bed dielectric-barrier discharge reactor to generate the non-thermal plasma. We report the effect of three different types of material filling the reactor: glass, zirconia, and titania. The titania filled reactor shows the greatest selectivity for producing CO


2015 ◽  
Vol 46 (1) ◽  
pp. 101-107 ◽  
Author(s):  
Padrig B. Flynn ◽  
Sarah Higginbotham ◽  
Nid’a H. Alshraiedeh ◽  
Sean P. Gorman ◽  
William G. Graham ◽  
...  

Foods ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 2927
Author(s):  
Vladimír Scholtz ◽  
Jana Jirešová ◽  
Božena Šerá ◽  
Jaroslav Julák

Cereals, an important food for humans and animals, may carry microbial contamination undesirable to the consumer or to the next generation of plants. Currently, non-thermal plasma (NTP) is often considered a new and safe microbicidal agent without or with very low adverse side effects. NTP is a partially or fully ionized gas at room temperature, typically generated by various electric discharges and rich in reactive particles. This review summarizes the effects of NTP on various types of cereals and products. NTP has undisputed beneficial effects with high potential for future practical use in decontamination and disinfection.


2021 ◽  
Vol 109 ◽  
pp. 365-373
Author(s):  
Gabriela N. Pereira ◽  
Karina Cesca ◽  
Anelise Leal Vieira Cubas ◽  
Débora de Oliveira

2021 ◽  
Author(s):  
Pavel Galář ◽  
Josef Khun ◽  
Anna Fučíková ◽  
Kateřina Dohnalová ◽  
Tomáš Popelář ◽  
...  

Non-thermal plasma activated water can be used for cheap, easy and chemicals-free surface modification of nanoparticles, with all the reactive species originating solely in air and water.


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