scholarly journals A Review of Microbial Decontamination of Cereals by Non-Thermal Plasma

Foods ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 2927
Author(s):  
Vladimír Scholtz ◽  
Jana Jirešová ◽  
Božena Šerá ◽  
Jaroslav Julák

Cereals, an important food for humans and animals, may carry microbial contamination undesirable to the consumer or to the next generation of plants. Currently, non-thermal plasma (NTP) is often considered a new and safe microbicidal agent without or with very low adverse side effects. NTP is a partially or fully ionized gas at room temperature, typically generated by various electric discharges and rich in reactive particles. This review summarizes the effects of NTP on various types of cereals and products. NTP has undisputed beneficial effects with high potential for future practical use in decontamination and disinfection.

2021 ◽  
Vol 12 ◽  
Author(s):  
Vladimír Scholtz ◽  
Eva Vaňková ◽  
Petra Kašparová ◽  
Ramya Premanath ◽  
Iddya Karunasagar ◽  
...  

The acronym ESKAPE refers to a group of bacteria consisting of Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. They are important in human medicine as pathogens that show increasing resistance to commonly used antibiotics; thus, the search for new effective bactericidal agents is still topical. One of the possible alternatives is the use of non-thermal plasma (NTP), a partially ionized gas with the energy stored particularly in the free electrons, which has antimicrobial and anti-biofilm effects. Its mechanism of action includes the formation of pores in the bacterial membranes; therefore, resistance toward it is not developed. This paper focuses on the current overview of literature describing the use of NTP as a new promising tool against ESKAPE bacteria, both in planktonic and biofilm forms. Thus, it points to the fact that NTP treatment can be used for the decontamination of different types of liquids, medical materials, and devices or even surfaces used in various industries. In summary, the use of diverse experimental setups leads to very different efficiencies in inactivation. However, Gram-positive bacteria appear less susceptible compared to Gram-negative ones, in general.


2015 ◽  
Vol 293 ◽  
pp. 1-6 ◽  
Author(s):  
Feifei Han ◽  
Yuhan Yang ◽  
Jiaying Han ◽  
Jin Ouyang ◽  
Na Na

2020 ◽  
Vol 10 (18) ◽  
pp. 6257-6265
Author(s):  
Kai Li ◽  
Jian Ji ◽  
Miao He ◽  
Haibao Huang

Formaldehyde is a main indoor pollutant and its removal is essential to protect human health and meet strict environmental regulations.


2020 ◽  
Vol 22 (6) ◽  
pp. 2036-2048 ◽  
Author(s):  
Lusi A ◽  
Haiyang Hu ◽  
Xianglan Bai

Up to 78.6% of levoglucosan was obtainable from cellulose by combining non-thermal plasma pretreatment at room temperature and subsequent pyrolysis at 350–450 °C. The yield already reached 77.6% when the pretreated cellulose was pyrolyzed at 375 °C.


2015 ◽  
Vol 242 ◽  
pp. 274-286 ◽  
Author(s):  
Meijuan Lu ◽  
Rong Huang ◽  
Junliang Wu ◽  
Mingli Fu ◽  
Limin Chen ◽  
...  

2020 ◽  
Vol 6 (4) ◽  
pp. 214
Author(s):  
Jaroslav Lux ◽  
Radim Dobiáš ◽  
Ivana Kuklová ◽  
Radek Litvik ◽  
Vladimír Scholtz ◽  
...  

Onychomycosis is one of the most common nail disorders. Its current treatment is not satisfactorily effective and often causes adverse side effects. This study aims to determine the optimal conditions for non-thermal plasma (NTP) inactivation of the most common dermatophytes in vitro and to apply it in patient`s therapy. The in vitro exposure to NTP produced by negative DC corona discharge caused full inactivation of Trichophyton spp. if applied during the early growth phases. This effect decreased to negligible inactivation with the exposure applied six days after inoculation. In a group of 40 patients with onychomycosis, NTP therapy was combined with nail plate abrasion and refreshment (NPAR) or treatment with antimycotics. The cohort included 17 patients treated with NPAR combined with NTP, 11 patients treated with antimycotics and NTP, and 12 patients treated with NPAR alone. The combination of NPAR and NTP resulted in clinical cure in more than 70% of patients. The synergistic effect of NPAR and NTP caused 85.7% improvement of mycological cure confirmed by negative microscopy and culture of the affected nail plate. We conclude that NTP can significantly improve the treatment of onychomycosis.


Biomedicines ◽  
2020 ◽  
Vol 8 (9) ◽  
pp. 348
Author(s):  
Sarmistha Mitra ◽  
Neha Kaushik ◽  
Il Soo Moon ◽  
Eun Ha Choi ◽  
Nagendra Kumar Kaushik

Reactive oxygen species (ROS) are critical signaling molecules for neuronal physiology that stimulate growth and development and play vital roles in several pathways when in a balanced state, but they cause neurodegeneration when unbalanced. As ROS levels above a certain threshold cause the activation of the autophagy system, moderate levels of ROS can be used as treatment strategies. Currently, such treatments are used together with low-level laser or photodynamic therapies, photo-bio modulation, or infrared treatments, in different chronic diseases but not in the treatment of neurodegeneration. Recently, non-thermal plasma has been successfully used in biomedical applications and treatments, and beneficial effects such as differentiation, cell growth, and proliferation, stimulation of ROS based pathways have been observed. Besides the activation of a wide range of biological signaling pathways by generating ROS, plasma application can be an effective treatment in neuronal regeneration, as well as in neuronal diseases. In this review, we summarize the generation and role of ROS in neurons and provide critical insights into their potential benefits on neurons. We also discuss the underlying mechanisms of ROS on neuronal development. Regarding clinical applications, we focus on ROS-based neuronal growth and regeneration strategies and in the usage of non-thermal plasma in neuronal and CNS injury treatments.


Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1336
Author(s):  
Helena Motaln ◽  
Nina Recek ◽  
Boris Rogelj

Cold atmospheric plasma (CAP), an ionized gas operating at room temperature, has been increasingly studied with respect to its potential use in medicine, where its beneficial effects on tumor reduction in oncology have been demonstrated. This review discusses the cellular changes appearing in cell membranes, cytoplasm, various organelles, and DNA content upon cells’ direct or indirect exposure to CAP or CAP-activated media/solutions (PAM), respectively. In addition, the CAP/PAM impact on the main cellular processes of proliferation, migration, protein degradation and various forms of cell death is addressed, especially in light of CAP use in the oncology field of plasma medicine.


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